{"id":100,"date":"2023-01-01T10:54:43","date_gmt":"2023-01-01T10:54:43","guid":{"rendered":"https:\/\/pharmjournal.asscph.com\/?p=100"},"modified":"2024-07-19T14:21:39","modified_gmt":"2024-07-19T14:21:39","slug":"%d9%81%d8%b9%d9%91%d8%a7%d9%84%d9%8a%d8%a9-%d8%ac%d8%b1%d8%b9%d8%a9-%d8%b9%d8%a7%d9%84%d9%8a%d8%a9-%d9%85%d9%86-%d9%81%d9%8a%d8%aa%d8%a7%d9%85%d9%8a%d9%86-d3-%d8%a8%d8%a7%d9%84%d9%85%d8%b4%d8%a7%d8%b1","status":"publish","type":"post","link":"https:\/\/pharmjournal.asscph.com\/?p=100","title":{"rendered":"\u0641\u0639\u0651\u0627\u0644\u064a\u0629 \u062c\u0631\u0639\u0629 \u0639\u0627\u0644\u064a\u0629 \u0645\u0646 \u0641\u064a\u062a\u0627\u0645\u064a\u0646 D3 \u0628\u0627\u0644\u0645\u0634\u0627\u0631\u0643\u0629 \u0645\u0639 \u0627\u0644\u0643\u0627\u0644\u0633\u064a\u0648\u0645 \u0648\u0631\u064a\u0632\u064a\u062f\u0631\u0648\u0646\u0627\u062a \u0644\u062a\u062f\u0628\u064a\u0631 \u062e\u0633\u0627\u0631\u0629 \u0627\u0644\u0639\u0638\u0645 \u0627\u0644\u0645\u0635\u0627\u062d\u0628\u0629 \u0644\u0645\u062b\u0628\u0637\u0627\u062a \u0627\u0644\u0623\u0631\u0648\u0645\u0627\u062a\u0627\u0632 \u0644\u062f\u0649 \u0645\u0631\u064a\u0636\u0627\u062a \u0633\u0631\u0637\u0627\u0646 \u062b\u062f\u064a \u0628\u0627\u0643\u0631"},"content":{"rendered":"

\u0627\u0644\u0645\u0642\u062f\u0645\u0629 Introduction:<\/span><\/strong><\/p>\n

\u064a\u064f\u0639\u062f\u0651 \u0633\u0631\u0637\u0627\u0646 \u0627\u0644\u062b\u062f\u064a \u0623\u062d\u062f \u0623\u0647\u0645 \u0627\u0644\u0645\u0634\u0643\u0644\u0627\u062a \u0627\u0644\u0635\u062d\u064a\u0629 \u0627\u0644\u062a\u064a \u062a\u0648\u0627\u062c\u0647 \u0646\u0633\u0627\u0621 \u0627\u0644\u0639\u0627\u0644\u0645\u060c \u0646\u0638\u0631\u0627\u064b \u0644\u0643\u0648\u0646\u0647 \u0623\u0643\u062b\u0631 \u0627\u0644\u062e\u0628\u0627\u062b\u0627\u062a \u062a\u0634\u062e\u064a\u0635\u0627\u064b (11.7%)\u060c \u0648\u0627\u0644\u0645\u0633\u0628\u0651\u0628 \u0627\u0644\u0623\u0648\u0644 \u0644\u0644\u0648\u0641\u064a\u0627\u062a \u0627\u0644\u0646\u0627\u062c\u0645\u0629 \u0639\u0646 \u0627\u0644\u0633\u0651\u0631\u0637\u0627\u0646 \u0644\u062f\u064a\u0647\u0646\u060c \u0628\u0646\u0633\u0628\u0629 \u0642\u0627\u0631\u0628\u062a \u0627\u0644\u0640 15% (\u0645\u0646\u0638\u0645\u0629 \u0627\u0644\u0635\u0651\u062d\u0651\u0629 \u0627\u0644\u0639\u0627\u0644\u0645\u064a\u0651\u0629 World Health Organization WHO)) \u0639\u0627\u0645 2018). \u062a\u0642\u0651\u062f\u0631 \u0627\u0644\u0625\u062d\u0635\u0627\u0626\u064a\u0627\u062a \u0628\u0623\u0646\u0651 \u0646\u0633\u0628\u0629 \u062a\u0639\u0627\u062f\u0644 \u0627\u0644\u0640 75% \u0645\u0646 \u0633\u0631\u0637\u0627\u0646\u0627\u062a \u0627\u0644\u062b\u062f\u064a \u0625\u064a\u062c\u0627\u0628\u064a\u0651\u0629 \u0627\u0644\u0645\u0633\u062a\u0642\u0628\u0644\u0627\u062a \u0627\u0644\u0647\u0631\u0645\u0648\u0646\u064a\u0651\u0629\u061b \u0633\u0648\u0627\u0621 \u0645\u0633\u062a\u0642\u0628\u0644 \u0627\u0644\u0625\u0633\u062a\u0631\u0648\u062c\u064a\u0646 Estrogen Receptor (ER) \u0623\u0645 \u0645\u0633\u062a\u0642\u0628\u0644 \u0627\u0644\u0628\u0631\u0648\u062c\u064a\u0633\u062a\u0631\u0648\u0646 (PR) \u0623\u0645 \u0643\u0644\u064a\u0647\u0645\u0627 \u0645\u0639\u0627\u064b\u060c \u0648\u0647\u0630\u0627 \u0645\u0627 \u064a\u062f\u0644\u0651\u0644 \u0639\u0644\u0649 \u0623\u0647\u0645\u064a\u0629 \u0627\u0644\u062a\u0651\u062d\u0631\u064a\u0636 \u0627\u0644\u0647\u0631\u0645\u0648\u0646\u064a \u0641\u064a \u062a\u0637\u0648\u0631 \u0647\u0630\u0647 \u0627\u0644\u062e\u0628\u0627\u062b\u0627\u062a \u0648\u0646\u0645\u0648\u0647\u0627 2\u060c1 <\/sup><\/span>\u0634\u0643\u0651\u0644 \u0638\u0647\u0648\u0631 \u0627\u0644\u062c\u064a\u0644 \u0627\u0644\u062b\u0627\u0644\u062b \u0645\u0646 \u0645\u062b\u0628\u0637\u0627\u062a \u0627\u0644\u0623\u0631\u0648\u0645\u0627\u062a\u0627\u0632 Aromatase Inhibitors (AIs) \u0625\u0636\u0627\u0641\u0629 \u0645\u0647\u0645\u0629 \u0644\u062a\u0631\u0633\u0627\u0646\u0629 \u0627\u0644\u0639\u0644\u0627\u062c\u0627\u062a \u0627\u0644\u0645\u0639\u062a\u0645\u062f\u0629 \u0641\u064a \u062a\u062f\u0628\u064a\u0631 \u0633\u0631\u0637\u0627\u0646 \u0627\u0644\u062b\u062f\u064a \u0627\u064a\u062c\u0627\u0628\u064a \u0627\u0644\u0640 ER\u060c \u0633\u0648\u0627\u0621 \u0641\u064a \u0645\u0631\u0627\u062d\u0644\u0647 \u0627\u0644\u0645\u0628\u0643\u0631\u0629 \u0623\u0645 \u0641\u064a \u0627\u0644\u062f\u0627\u0621 \u0627\u0644\u0646\u0642\u064a\u0644\u064a\u060c \u0648\u0630\u0644\u0643 \u0644\u062f\u0649 \u0627\u0644\u0645\u0631\u064a\u0636\u0627\u062a \u0628\u0639\u062f \u0633\u0646 \u0627\u0644\u0625\u064a\u0627\u0633 \u0627\u0644\u0637\u0628\u064a\u0639\u064a \u0623\u0648 \u0627\u0644\u0645\u062d\u0631\u0651\u0636 \u062f\u0648\u0627\u0626\u064a\u0651\u0627\u064b \u0623\u0648 \u062c\u0631\u0627\u062d\u064a\u0651\u0627\u064b \u0623\u0648 \u0634\u0639\u0627\u0639\u064a\u0651\u0627\u064b. \u0648\u0642\u062f \u0623\u0633\u0647\u0645\u062a \u0647\u0630\u0647 \u0627\u0644\u062a\u0637\u0648\u0631\u0627\u062a \u0641\u064a \u0627\u0646\u062e\u0641\u0627\u0636 \u0645\u0639\u062f\u0644\u0627\u062a \u0627\u0644\u0646\u0643\u0633 \u0645\u0642\u0627\u0631\u0646\u0629 \u0628\u0623\u0646\u0638\u0645\u0629 \u0627\u0644\u0639\u0644\u0627\u062c \u0627\u0644\u0645\u0642\u062a\u0635\u0631\u0629 \u0639\u0644\u0649 \u0627\u0644\u062a\u0627\u0645\u0648\u0643\u0633\u064a\u0641\u064a\u0646 Tamoxifen (TAM)\u060c \u0627\u0644\u0623\u0645\u0631 \u0627\u0644\u0630\u064a \u0642\u0627\u062f \u0625\u0644\u0649 \u0627\u0639\u062a\u0645\u0627\u062f \u0645\u062b\u0628\u0637\u0627\u062a \u0627\u0644\u0623\u0631\u0648\u0645\u0627\u062a\u0627\u0632 \u0643\u0645\u0639\u0627\u0644\u062c\u0629 \u0645\u0641\u0631\u062f\u0629 monotherapy \u0623\u0648 \u062a\u0627\u0644\u064a\u0629 \u0644\u0644\u0639\u0644\u0627\u062c \u0628\u0627\u0644\u062a\u0627\u0645\u0648\u0643\u0633\u064a\u0641\u064a\u0646\u060c \u0648\u0644\u0645\u062f\u0629 \u062a\u062a\u0631\u0627\u0648\u062d \u0628\u064a\u0646 2 \u0625\u0644\u0649 3 \u0633\u0646\u0648\u0627\u062a. 3<\/sup>6<\/sup>–<\/sup> \u00a0<\/span>\u062a\u0634\u0645\u0644 \u0645\u062b\u0628\u0637\u0627\u062a \u0627\u0644\u062c\u064a\u0644 \u0627\u0644\u062b\u0627\u0644\u062b \u0644\u0644\u0623\u0631\u0648\u0645\u0627\u062a\u0627\u0632 \u0648\u0627\u0644\u062a\u064a \u062d\u0627\u0632\u062a \u0645\u0635\u0627\u062f\u0642\u0629 \u0625\u062f\u0627\u0631\u0629 \u0627\u0644\u0623\u063a\u0630\u064a\u0629 \u0648\u0627\u0644\u0623\u062f\u0648\u064a\u0629 \u0627\u0644\u0623\u0645\u0631\u064a\u0643\u064a\u0629 Food and Drugs Administration (FDA) \u062b\u0644\u0627\u062b\u0629 \u0645\u0631\u0643\u0628\u0627\u062a \u0639\u0627\u0644\u064a\u0629 \u0627\u0644\u0646\u0651\u0648\u0639\u064a\u0651\u0629 \u0647\u064a \u00a0Anastrozole\u0648Letrozole\u00a0 <\/strong>\u0648Exemestane. \u063a\u064a\u0631 \u0623\u0646\u0651 \u0645\u062b\u0628\u0637\u0627\u062a \u0627\u0644\u0623\u0631\u0648\u0645\u0627\u062a\u0627\u0632 \u062a\u062a\u0633\u0628\u0651\u0628 \u0628\u062d\u062f\u0648\u062b \u062a\u0623\u062b\u064a\u0631\u064d \u0636\u0627\u0626\u0631\u064d \u064a\u064f\u0639\u0631\u0641 \u0628\u0640 ” \u062e\u0633\u0627\u0631\u0629 \u0627\u0644\u0639\u0638\u0645 \u0627\u0644\u0645\u0635\u0627\u062d\u0628\u0629 \u0644\u0645\u062b\u0628\u0637\u0627\u062a \u0627\u0644\u0623\u0631\u0648\u0645\u0627\u062a\u0627\u0632 Aromatase Inhibitor-Associated Bone Loss (AIBL)”\u060c \u0648\u0627\u0644\u0630\u064a \u064a\u062a\u062c\u0644\u0649 \u0628\u062a\u062f\u0647\u0648\u0631 \u0645\u0644\u062d\u0648\u0638 \u0641\u064a \u0627\u0644\u0628\u0646\u064a\u0629 \u0627\u0644\u0645\u0639\u0645\u0627\u0631\u064a\u0629 \u0644\u0644\u0646\u0633\u064a\u062c \u0627\u0644\u0639\u0638\u0645\u064a.7<\/sup>\u060c<\/sup>8<\/sup> \u0648\u064a\u0639\u0632\u0649 \u0647\u0630\u0627 \u0627\u0644\u062a\u0623\u062b\u064a\u0631 \u0627\u0644\u0636\u0651\u0627\u0626\u0631 \u0627\u0644\u0630\u064a \u062a\u062d\u062f\u062b\u0647 \u0627\u0644\u0640 (AIs) \u0625\u0644\u0649 \u062a\u062b\u0628\u064a\u0637\u0647\u0627 \u062a\u062d\u0648\u0651\u0644 \u0627\u0644\u062a\u064a\u0633\u062a\u0648\u0633\u062a\u064a\u0631\u0648\u0646 \u0627\u0644\u0645\u062d\u064a\u0637\u064a \u0627\u0644\u0645\u062a\u0648\u0627\u0633\u0637 \u0628\u0625\u0646\u0632\u064a\u0645 \u0627\u0644\u0623\u0631\u0648\u0645\u0627\u062a\u0627\u0632 \u0625\u0644\u0649 \u0625\u0633\u062a\u0631\u0648\u062c\u064a\u0646\u060c \u0627\u0644\u0623\u0645\u0631 \u0627\u0644\u0630\u064a \u064a\u0641\u0636\u064a \u0628\u0627\u0644\u0645\u062d\u0635\u0644\u0629 \u0625\u0644\u0649 \u0646\u0641\u0627\u062f \u0634\u0628\u0647 \u062a\u0627\u0645 \u0644\u0644\u0625\u0633\u062a\u0631\u0648\u062c\u064a\u0646\u060c \u0648\u0645\u0627 \u064a\u062a\u0631\u062a\u0651\u0628 \u0639\u0644\u0649 \u0630\u0644\u0643 \u0645\u0646 \u0632\u064a\u0627\u062f\u0629\u064d \u0641\u064a \u062a\u0642\u0644\u0651\u0628 \u0627\u0644\u0639\u0638\u0645 \u0648\u062a\u0632\u0627\u064a\u062f\u064d \u0641\u064a \u0641\u0639\u0627\u0644\u064a\u0629 \u0646\u0627\u0642\u0636\u0627\u062a \u0627\u0644\u0639\u0638\u0645 Osteoclasts\u060c \u0648\u062a\u0646\u0627\u0642\u0635\u064d \u0641\u064a \u0627\u0644\u0643\u062b\u0627\u0641\u0629 \u0627\u0644\u0645\u0639\u062f\u0646\u064a\u0629 \u0644\u0644\u0639\u0638\u0645 Bone Mineral Density (BMD)\u060c \u0648\u062e\u0633\u0627\u0631\u0629 \u0645\u062a\u0633\u0627\u0631\u0639\u0629 \u0641\u064a \u0627\u0644\u0639\u0638\u0645 \u0623\u0639\u0644\u0649 \u0628\u0645\u0631\u062a\u064a\u0646 \u0645\u0646 \u062e\u0633\u0627\u0631\u0629 \u0627\u0644\u0639\u0638\u0645 \u0627\u0644\u0645\u062a\u0631\u0627\u0641\u0642\u0629 \u0645\u0639 \u0627\u0644\u0625\u064a\u0627\u0633 \u0627\u0644\u0637\u0628\u064a\u0639\u064a\u060c \u0648\u0628\u0627\u0644\u0645\u062d\u0635\u0644\u0629\u060c \u0627\u0631\u062a\u0641\u0627\u0639 \u0641\u064a \u0645\u0639\u062f\u0644\u0627\u062a \u0627\u0644\u0643\u0633\u0648\u0631 \u0628\u0646\u0633\u0628\u0629 \u062a\u062a\u0631\u0627\u0648\u062d \u0628\u064a\u0646 1-4%.<\/strong>6<\/sup>–<\/sup>12 <\/sup><\/span>\u0641\u064a \u0633\u064a\u0627\u0642 \u0645\u062a\u0635\u0644\u060c \u064a\u0634\u0643\u0651\u0644 \u0639\u0648\u0632 \u0641\u064a\u062a\u0627\u0645\u064a\u0646 D \u0623\u0648 \u0639\u062f\u0645 \u0643\u0641\u0627\u064a\u062a\u0647 Vitamin D deficiency\/insufficiency \u0648\u0628\u0627\u0621\u064b \u0635\u0627\u0645\u062a\u0627\u064b \u0648\u064a\u0639\u062f\u0651 \u0645\u0634\u0643\u0644\u0629\u064b \u0635\u0651\u062d\u064a\u0651\u0629\u064b \u0630\u0627\u062a \u0623\u0647\u0645\u064a\u0651\u0629 \u062e\u0627\u0635\u0651\u0629 \u0644\u062f\u0649 \u0627\u0644\u062c\u0645\u0647\u0631\u0627\u062a \u0639\u0627\u0644\u064a\u0629 \u0627\u0644\u062e\u0637\u0648\u0631\u0629 \u0645\u062b\u0644 \u0645\u0631\u064a\u0636\u0627\u062a \u0633\u0631\u0637\u0627\u0646 \u0627\u0644\u062b\u062f\u064a \u0648\u0639\u0644\u0649 \u0648\u062c\u0647 \u0627\u0644\u062e\u0635\u0648\u0635 \u0627\u0644\u0645\u0639\u0627\u0644\u062c\u0627\u062a \u0628\u0645\u062b\u0628\u0637\u0627\u062a \u0627\u0644\u0623\u0631\u0648\u0645\u0627\u062a\u0627\u0632. \u0648\u062a\u064f\u0639\u0631\u0651\u0641 \u0645\u0639\u0627\u0647\u062f \u0627\u0644\u0637\u0628 \u0627\u0644\u0623\u0645\u0631\u064a\u0643\u064a\u0651\u0629 US Institutes of Medicine (IOM) \u0639\u0648\u0632 \u0641\u064a\u062a\u0627\u0645\u064a\u0646 D3<\/sub> \u0628\u0643\u0648\u0646\u0647 \u062a\u062f\u0646\u064a\u0627\u064b \u0641\u064a \u062a\u0631\u0627\u0643\u064a\u0632 25 \u0647\u064a\u062f\u0631\u0648\u0643\u0633\u064a \u0643\u0627\u0644\u0633\u064a\u0641\u064a\u0631\u0648\u0644 25-hydroxycholecalciferol (\u0623\u064a 25(OH)D) \u0625\u0644\u0649 \u0645\u0627 \u062f\u0648\u0646 \u0627\u0644\u0640 12 \u0646\u063a\/\u0645\u0644\u060c \u0641\u064a \u062d\u064a\u0646 \u062a\u064f\u0639\u0631\u0651\u0641 \u0627\u0644\u0643\u0641\u0627\u064a\u0629 \u0645\u0646 \u0641\u064a\u062a\u0627\u0645\u064a\u0646 D3<\/sub> \u0628\u062a\u0631\u0627\u0643\u064a\u0632 25(OH)D \u062a\u0641\u0648\u0642 \u0627\u0644\u0640 20 \u0646\u063a\/\u0645\u0644. \u0648\u0627\u0644\u062c\u062f\u064a\u0631 \u0628\u0627\u0644\u0627\u0647\u062a\u0645\u0627\u0645 \u0623\u0646\u0651 \u0627\u0644\u062d\u062f \u0627\u0644\u0623\u0639\u0644\u0649 \u0627\u0644\u0645\u0648\u0635\u0649 \u0628\u0647 \u0645\u0646 \u0642\u0628\u0644 IOM \u0644\u062c\u0631\u0639\u0629 \u0641\u064a\u062a\u0627\u0645\u064a\u0646 D3<\/sub> \u0644\u062f\u0649 \u0627\u0644\u0628\u0627\u0644\u063a\u064a\u0646 \u0644\u0627 \u064a\u062a\u062c\u0627\u0648\u0632 \u0639\u062a\u0628\u0629 2000 \u0648\u062d\u062f\u0629 \u062f\u0648\u0644\u064a\u0651\u0629 (IU) \u064a\u0648\u0645\u064a\u0627\u064b\u060c \u0648\u0644\u0643\u0646 \u0647\u0630\u0647 \u0627\u0644\u062c\u0631\u0639\u0629 \u0648\u0641\u0642\u0627\u064b \u0644\u062f\u0631\u0627\u0633\u0629 Cannell \u00a0\u0648\u0632\u0645\u0644\u0627\u0626\u0647 (<\/em>2008) \u0648\u0625\u0646 \u0643\u0627\u0646\u062a \u0643\u0627\u0641\u064a\u0629\u064c \u0644\u0644\u0648\u0635\u0648\u0644 \u0628\u062a\u0631\u0643\u064a\u0632 25(OH)D \u0625\u0644\u0649 \u062d\u062f\u0648\u062f 30 \u0646\u063a\/\u0645\u0644 \u0641\u064a \u062d\u0627\u0644 \u0643\u0627\u0646 \u0627\u0644\u062a\u0631\u0643\u064a\u0632 \u0627\u0644\u0628\u062f\u0626\u064a 10 \u0646\u063a\/\u0645\u0644\u060c \u0625\u0644\u0651\u0627 \u0623\u0646\u0651\u0647\u0627 \u0648\u0628\u0627\u0644\u0645\u0642\u0627\u0628\u0644 \u062a\u062e\u0641\u0642 \u0641\u064a \u0632\u064a\u0627\u062f\u0629 \u0627\u0644\u0645\u0633\u062a\u0648\u064a\u0627\u062a \u0627\u0644\u0628\u0644\u0627\u0632\u0645\u064a\u0629 \u0627\u0644\u0628\u062f\u0626\u064a\u0629 \u0645\u0646 30 \u0646\u063a\/\u0645\u0644 \u0644\u062d\u062f\u0648\u062f 50 \u0646\u063a\/\u0645\u0644\u060c \u062d\u062a\u0649 \u0648\u0625\u0646 \u0627\u0633\u062a\u0639\u0645\u0644\u062a \u0644\u0645\u062f\u0629 \u0632\u0645\u0646\u064a\u0629 \u0637\u0648\u064a\u0644\u0629\u060c \u062d\u064a\u062b \u062a\u0635\u0628\u062d \u0627\u0644\u0639\u0644\u0627\u0642\u0629 \u0628\u064a\u0646 \u0627\u0644\u062a\u0631\u0643\u064a\u0632 \u0648\u0627\u0644\u0632\u0645\u0646 \u063a\u064a\u0631 \u062e\u0637\u064a\u0651\u0629 \u0628\u0639\u062f \u062a\u062e\u0637\u064a \u0627\u0644\u062a\u0651\u0631\u0627\u0643\u064a\u0632 \u0642\u064a\u0645\u0629 \u0627\u0644\u0640 30 \u0646\u063a\/\u0645\u0644. 12<\/sup>–<\/sup>14 <\/sup><\/span>\u0623\u0641\u0636\u062a \u0627\u0644\u0645\u0631\u0627\u062c\u0639\u0629 \u0627\u0644\u0645\u0646\u0647\u062c\u064a\u0629 \u0644\u0640 Bischoff \u0648\u0632\u0645\u0644\u0627\u0626\u0647 (2006) \u0625\u0644\u0649 \u0623\u0646\u0651 \u0627\u0644\u062a\u0631\u0643\u064a\u0632 \u0627\u0644\u0623\u062f\u0646\u0649 \u0645\u0646 25(OH) D \u0627\u0644\u0642\u0627\u062f\u0631 \u0639\u0644\u0649 \u062a\u062d\u0642\u064a\u0642 \u0645\u062c\u0645\u0644 \u0627\u0644\u0645\u062d\u0635\u0644\u0627\u062a \u0627\u0644\u0639\u0644\u0627\u062c\u064a\u0629 (\u0628\u0645\u0627 \u0641\u064a\u0647\u0627 \u062a\u062d\u0633\u0646 \u0642\u064a\u0645\u0629 \u0627\u0644\u0640 BMD) \u0644\u062f\u0649 \u0627\u0644\u0623\u0641\u0631\u0627\u062f \u0627\u0644\u0623\u0635\u062d\u0627\u0621 \u064a\u0628\u0644\u063a 30 \u0646\u063a\/\u0645\u0644\u060c \u0648\u0623\u0646\u0651 \u0627\u0644\u062a\u0631\u0643\u064a\u0632 \u0627\u0644\u0623\u0645\u062b\u0644 \u0644\u0640 25(OH) D \u0644\u062a\u062d\u0642\u064a\u0642 \u0647\u0630\u0647 \u0627\u0644\u0645\u062d\u0635\u0644\u0627\u062a \u064a\u062a\u0631\u0627\u0648\u062d \u0628\u064a\u0646 36-40 \u0646\u063a\/\u0645\u0644. \u0643\u0645\u0627 \u062e\u0644\u0635\u062a \u062f\u0631\u0627\u0633\u0629 Mohr \u0648\u0632\u0645\u0644\u0627\u0626\u0647 (2014) \u0648\u0627\u0644\u062a\u064a \u0627\u0639\u062a\u0645\u062f\u062a \u0645\u0646\u0647\u062c\u064a\u0629 \u0627\u0644\u062a\u062d\u0644\u064a\u0644 \u0627\u0644\u062a\u0651\u0644\u0648\u064a Meta-Analysis \u0644\u062e\u0645\u0633 \u062f\u0631\u0627\u0633\u0627\u062a \u0633\u0631\u064a\u0631\u064a\u0629 \u0625\u0644\u0649 \u062a\u062d\u0633\u0651\u0646 \u0628\u0642\u064a\u0627 \u0645\u0631\u064a\u0636\u0627\u062a \u0633\u0631\u0637\u0627\u0646 \u0627\u0644\u062b\u062f\u064a \u0644\u062f\u0649 \u062a\u062d\u0642\u064a\u0642 \u0645\u0633\u062a\u0648\u064a\u0627\u062a \u0645\u0635\u0644\u064a\u0629 \u0645\u0646 25(OH)D \u062a\u062a\u0631\u0627\u0648\u062d \u0628\u064a\u0646 30-70 \u0646\u063a\/\u0645\u0644\u060c \u0648\u0627\u0642\u062a\u0631\u0646\u062a \u0627\u0644\u0645\u0633\u062a\u0648\u064a\u0627\u062a \u0627\u0644\u0645\u0635\u0644\u064a\u0629 \u0627\u0644\u0623\u0639\u0644\u0649 \u0645\u0639 \u062a\u0631\u0627\u062c\u0639 \u0645\u0639\u062f\u0644\u0627\u062a \u0627\u0644\u0648\u0641\u064a\u0627\u062a \u0628\u0645\u0642\u062f\u0627\u0631 \u0627\u0644\u0646\u0635\u0641 \u062a\u0642\u0631\u064a\u0628\u0627\u064b.14<\/sup>\u060c<\/sup>15 <\/sup><\/span>\u064a\u062a\u0645\u0651 \u062a\u062f\u0628\u064a\u0631 \u0627\u0644\u0640 (AIBL) \u0648\u0641\u0642 \u062a\u0648\u0635\u064a\u0627\u062a \u0627\u0644\u062f\u0644\u064a\u0644 \u0627\u0644\u0625\u0631\u0634\u0627\u062f\u064a \u0644\u0644\u062c\u0645\u0639\u064a\u0629 \u0627\u0644\u0623\u0645\u0631\u064a\u0643\u064a\u0629 \u0644\u0637\u0628 \u0627\u0644\u0623\u0648\u0631\u0627\u0645 \u0627\u0644\u0633\u0631\u064a\u0631\u064a American Society of Clinical Oncology \u00a0<\/strong>(ASCO) \u0628\u0627\u0633\u062a\u062e\u062f\u0627\u0645 \u0645\u0636\u0627\u062f\u0627\u062a \u0627\u0631\u062a\u0634\u0627\u0641 \u0627\u0644\u0639\u0638\u0645 (\u0627\u0644\u0641\u0633\u0641\u0648\u0646\u0627\u062a \u0627\u0644\u062b\u0646\u0627\u0626\u064a\u0629 \u0645\u062b\u0644 \u0631\u064a\u0632\u064a\u062f\u0631\u0648\u0646\u0627\u062a \u0623\u0648 \u0628\u064a\u0645\u064a\u062f\u0631\u0648\u0646\u0627\u062a \u0623\u0648 \u0632\u0648\u0644\u064a\u0646\u062f\u0631\u064a\u0646\u064a\u0643 \u0627\u0633\u064a\u062f) \u0628\u0627\u0644\u0645\u0634\u0627\u0631\u0643\u0629 \u0645\u0639 \u0641\u064a\u062a\u0627\u0645\u064a\u0646 D3<\/sub> \u0628\u062c\u0631\u0639\u0629 \u0642\u062f\u0631\u0647\u0627 800 \u0648\u062d\u062f\u0629 \u062f\u0648\u0644\u064a\u0629 \u064a\u0648\u0645\u064a\u0627\u064b\u060c \u0648\u062c\u0631\u0639\u0629 \u0645\u0646 \u0627\u0644\u0643\u0627\u0644\u0633\u064a\u0648\u0645 \u0627\u0644\u0639\u0646\u0635\u0631\u064a \u062a\u0639\u0627\u062f\u0644 1000 \u0645\u0644\u063a \u064a\u0648\u0645\u064a\u0627\u064b.8<\/sup> \u063a\u064a\u0631 \u0623\u0646\u0651 \u062f\u0631\u0627\u0633\u0629 \u0645\u0631\u0627\u062c\u0639\u0629 \u0634\u0645\u0648\u0644\u064a\u0651\u0629 \u0644\u0640 16 \u062f\u0631\u0627\u0633\u0629 \u0633\u0631\u064a\u0631\u064a\u0651\u0629 \u0642\u062f \u062a\u0648\u0635\u0651\u0644\u062a \u0625\u0644\u0649 \u0641\u0634\u0644 \u062c\u0631\u0639\u0627\u062a \u0627\u0644\u0643\u0627\u0644\u0633\u064a\u0648\u0645 (500-1500 \u0645\u0644\u063a) \u0648\u0641\u064a\u062a\u0627\u0645\u064a\u0646 D (200 \u0625\u0644\u0649 1000 \u0648\u062d\u062f\u0629 \u062f\u0648\u0644\u064a\u0651\u0629) \u0648\u0627\u0644\u062a\u064a \u062a\u0645\u0651 \u062a\u0642\u064a\u064a\u0645\u0647\u0627 \u0641\u064a \u0645\u0646\u0639 \u0627\u0644\u062e\u0633\u0627\u0631\u0629 \u0627\u0644\u062d\u0627\u0635\u0644\u0629 \u0641\u064a \u0627\u0644\u0640 BMD \u0644\u062f\u0649 \u0646\u0651\u0633\u0627\u0621 \u062a\u0644\u0642\u064a\u0646 \u0639\u0644\u0627\u062c\u0627\u064b \u0628\u0640 AIs.16<\/sup> \u0648\u0641\u064a \u0627\u062a\u0633\u0627\u0642 \u0645\u0639 \u0647\u0630\u0647 \u0627\u0644\u0646\u062a\u0627\u0626\u062c\u060c \u0628\u0631\u0647\u0646\u062a \u062f\u0631\u0627\u0633\u0629 Prieto-Alhambra <\/a>\u00a0\u0648\u0632\u0645\u0644\u0627\u0626\u0647 (2011) \u0639\u0644\u0649 \u0623\u0646\u0651 \u062a\u062d\u0633\u0651\u0646 \u062a\u0631\u0627\u0643\u064a\u0632 \u0641\u064a\u062a\u0627\u0645\u064a\u0646 D \u0648\u0635\u0648\u0644\u0627\u064b \u0625\u0644\u0649 \u0642\u064a\u0645 \u2264 40 \u0646\u063a\/\u0645\u0644 \u0644\u062f\u0649 \u0625\u0639\u0637\u0627\u0621 \u0645\u062a\u0645\u0645\u0627\u062a \u062a\u0642\u062a\u0635\u0631 \u064a\u0648\u0645\u064a\u0651\u0627\u064b \u0639\u0644\u0649 \u062c\u0631\u0639\u0627\u062a \u0645\u0646 \u0627\u0644\u0643\u0627\u0644\u0633\u064a\u0648\u0645 (1 \u063a) \u0648\u0641\u064a\u062a\u0627\u0645\u064a\u0646 D3 (800 \u0648\u062d\u062f\u0629 \u062f\u0648\u0644\u064a\u0651\u0629) \u0625\u0636\u0627\u0641\u0629 \u0625\u0644\u0649 16 \u0623\u0644\u0641 \u0648\u062d\u062f\u0629 \u062f\u0648\u0644\u064a\u0651\u0629 \u0641\u0645\u0648\u064a\u0651\u0627\u064b \u0643\u0644\u0651 \u0623\u0633\u0628\u0648\u0639\u064a\u0646 (\u062f\u0648\u0646 \u0627\u0644\u0641\u0633\u0641\u0648\u0646\u0627\u062a \u0627\u0644\u062b\u0646\u0627\u0626\u064a\u0651\u0629) \u0644\u0645\u0631\u064a\u0636\u0627\u062a \u0633\u0631\u0637\u0627\u0646 \u062b\u062f\u064a \u0645\u0639\u0627\u0644\u062c\u0627\u062a \u0628\u0640 AI \u0642\u062f \u062a\u0631\u0627\u0641\u0642 \u0645\u0639 \u062a\u0631\u0627\u062c\u0639 \u0641\u064a \u062e\u0633\u0627\u0631\u0629 \u0627\u0644\u0639\u0638\u0645 \u0627\u0644\u0645\u0635\u0627\u062d\u0628 \u0644\u0640 AIs \u0628\u0627\u0644\u0645\u0642\u0627\u0631\u0646\u0629 \u0645\u0639 \u062e\u0633\u0627\u0631\u0629\u064d \u0623\u0643\u0628\u0631 \u0633\u062c\u0651\u0644\u062a \u0644\u062f\u0649 \u0627\u0644\u0645\u0631\u064a\u0636\u0627\u062a \u0628\u062a\u0631\u0627\u0643\u064a\u0632 \u2264 30 \u0646\u063a\/\u0645\u0644.17<\/sup> \u0648\u0628\u0627\u0644\u0646\u0638\u0631 \u0625\u0644\u0649 \u0645\u0627 \u0633\u0628\u0642\u060c \u0641\u0625\u0646\u0651 \u0645\u0646 \u0627\u0644\u0636\u0631\u0648\u0631\u0629 \u0628\u0645\u0643\u0627\u0646 \u0627\u0644\u0648\u0635\u0648\u0644 \u0628\u062a\u0631\u0627\u0643\u064a\u0632 \u0627\u0644\u0640 25(OH)D \u0625\u0644\u0649 \u0642\u064a\u0645\u064d \u062a\u0641\u0648\u0642 \u0627\u0644\u0642\u064a\u0645\u0629 \u0627\u0644\u062d\u062f\u0651\u064a\u0651\u0629 \u0644\u0644\u0643\u0641\u0627\u064a\u0629 \u0648\u0627\u0644\u0648\u0627\u0631\u062f\u0629 \u0641\u064a \u062a\u0648\u0635\u064a\u0627\u062a IOM \u0644\u062f\u0649 \u0645\u0631\u064a\u0636\u0627\u062a \u0633\u0631\u0637\u0627\u0646 \u0627\u0644\u062b\u062f\u064a \u0627\u0644\u0644\u0627 \u0646\u0642\u064a\u0644\u064a \u0627\u0644\u0645\u0639\u0627\u0644\u062c\u0627\u062a \u0628\u0645\u062b\u0628\u0637\u0627\u062a \u0627\u0644\u0623\u0631\u0648\u0645\u0627\u062a\u0627\u0632 \u0644\u064a\u0643\u0648\u0646 \u0628\u0627\u0644\u0625\u0645\u0643\u0627\u0646 \u062a\u062c\u0646\u064a\u0628\u0647\u0646\u0651 \u0627\u0644\u062a\u0623\u062b\u064a\u0631\u0627\u062a \u0627\u0644\u0636\u0627\u0631\u0651\u0629 \u0644\u0640 AIs \u0641\u064a \u0635\u062d\u0651\u0629 \u0627\u0644\u0639\u0638\u0627\u0645. \u0648\u0645\u0646 \u062c\u0627\u0646\u0628 \u0622\u062e\u0631\u060c \u0641\u0625\u0646\u0651 \u0627\u0644\u062c\u0631\u0639\u0627\u062a \u0627\u0644\u0644\u0627\u0632\u0645\u0629 \u0644\u0644\u0648\u0635\u0648\u0644 \u0625\u0644\u0649 \u0647\u0630\u0647 \u0627\u0644\u062a\u0651\u0631\u0627\u0643\u064a\u0632 \u0628\u063a\u064a\u0627\u0628 \u062a\u0639\u0631\u0651\u0636 \u0643\u0627\u0641\u064d \u0644\u0623\u0634\u0639\u0629 \u0627\u0644\u0634\u0645\u0633 \u062a\u0642\u062f\u0651\u0631 \u0648\u0641\u0642\u0627\u064b \u0644\u062f\u0631\u0627\u0633\u0629 Cannell \u0648\u0632\u0645\u0644\u0627\u0626\u0647 (2008) \u0628\u0642\u0631\u0627\u0628\u0629 1000 \u0648\u062d\u062f\u0629 \u062f\u0648\u0644\u064a\u0629 (IU) \u0644\u0643\u0644 15 \u0643\u063a (\u0623\u064a 67 IU \u0644\u0643\u0644 1 \u0643\u063a)\u060c \u0623\u064a \u0628\u062d\u062f\u0648\u062f 5000 IU \u064a\u0648\u0645\u064a\u0627\u064b \u0644\u0644\u0634\u062e\u0635 \u0627\u0644\u0628\u0627\u0644\u063a \u0628\u0648\u0632\u0646 70 \u0643\u063a\u060c \u0648\u062a\u0645\u062b\u0651\u0644 \u0647\u0630\u0647 \u0627\u0644\u062c\u0631\u0639\u0629 \u0633\u062a\u0629 \u0623\u0636\u0639\u0627\u0641 \u0627\u0644\u062c\u0631\u0639\u0629 \u0627\u0644\u0645\u0648\u0635\u0649 \u0628\u0647\u0627 \u0645\u0646 \u0642\u0628\u0644\u00a0 <\/strong>ASCO \u0644\u062a\u062f\u0628\u064a\u0631 \u0627\u0644\u0640 AIBL.<\/strong> \u0648\u0641\u064a \u0633\u064a\u0627\u0642 \u0645\u062a\u0635\u0644\u060c \u0628\u064a\u0646\u062a \u062a\u0648\u0635\u064a\u0627\u062a \u0627\u0644\u062f\u0644\u064a\u0644 \u0627\u0644\u0627\u0631\u0634\u0627\u062f\u064a \u0627\u0644\u0633\u0631\u064a\u0631\u064a \u0644\u0644\u062c\u0645\u0639\u064a\u0629 \u0627\u0644\u0623\u0645\u0631\u064a\u0643\u064a\u0651\u0629 \u0644\u0644\u063a\u062f\u062f \u0627\u0644\u0635\u0651\u0645 American Endocrine Society \u0644\u0639\u0627\u0645 2011 \u0639\u0644\u0649 \u0623\u0646\u0651 \u0645\u0639\u0627\u0644\u062c\u0629 \u062d\u0627\u0644\u0629 \u0627\u0644\u0639\u0648\u0632 \u0645\u0646 \u0641\u064a\u062a\u0627\u0645\u064a\u0646 D3<\/sub> \u064a\u062a\u0637\u0644\u0628 \u0627\u0633\u062a\u062e\u062f\u0627\u0645 \u062c\u0631\u0639\u0629 6000 IU \u064a\u0648\u0645\u064a\u0627\u064b (50000 IU \u00a0\u0623\u0633\u0628\u0648\u0639\u064a\u0627\u064b) \u0644\u0645\u062f\u0629 8 \u0623\u0633\u0627\u0628\u064a\u0639 \u0644\u062a\u062d\u0642\u064a\u0642 \u062a\u0631\u0643\u064a\u0632 \u0645\u0646 25(OH)D \u064a\u0641\u0648\u0642 30 \u0646\u063a \/\u0645\u0644\u060c \u0648\u0645\u0646 \u062b\u0645 \u062c\u0631\u0639\u0629 \u0635\u064a\u0627\u0646\u0629 \u062a\u062a\u0631\u0627\u0648\u062d \u0628\u064a\u0646 1500- 2000IU \/\u064a\u0648\u0645\u064a\u0627\u064b. 7<\/sup>\u060c<\/sup>12<\/sup>\u060c<\/sup>13<\/sup> \u0648\u0647\u0630\u0627 \u0645\u0627 \u064a\u0639\u0632\u0651\u0632 \u0627\u0644\u062d\u0627\u062c\u0629 \u0644\u0625\u062c\u0631\u0627\u0621 \u062f\u0631\u0627\u0633\u0629 \u0633\u0631\u064a\u0631\u064a\u0629 \u062a\u0633\u062a\u0647\u062f\u0641 \u062a\u0642\u064a\u064a\u0645 \u0641\u0639\u0627\u0644\u064a\u0629 \u0648\u0645\u0623\u0645\u0648\u0646\u064a\u0629 \u0625\u0636\u0627\u0641\u0629 \u062c\u0631\u0639\u0629 \u0639\u0627\u0644\u064a\u0629 \u0642\u062f\u0631\u0647\u0627 (5000 (IU \u0645\u0646 \u0641\u064a\u062a\u0627\u0645\u064a\u0646 D3<\/sub><\/strong> \u0627\u0644\u0649 \u0627\u0644\u0628\u0631\u0646\u0627\u0645\u062c \u0627\u0644\u0639\u0644\u0627\u062c\u064a \u0644\u0644\u0640 ASCO \u0628\u0647\u062f\u0641 \u0627\u0644\u0648\u0642\u0627\u064a\u0629 \u0645\u0646 \u062e\u0633\u0627\u0631\u0629 \u0627\u0644\u0639\u0638\u0645 \u0648\u0639\u0644\u0627\u062c \u0627\u0644\u062a\u062e\u0644\u062e\u0644 \u0627\u0644\u0639\u0638\u0645\u064a \u0627\u0644\u0645\u062d\u062f\u062b \u0628\u0640 AIs \u0644\u062f\u0649 \u0645\u0631\u064a\u0636\u0627\u062a \u0633\u0631\u0637\u0627\u0646 \u0627\u0644\u062b\u062f\u064a \u0627\u0644\u0644\u0627 \u0646\u0642\u064a\u0644\u064a.<\/span><\/p>\n

\u0627\u0644\u0637\u0631\u0642 <\/strong>Methods<\/strong><\/span><\/p>\n

\u0635\u064f\u0645\u0651\u0645\u062a \u0647\u0630\u0647 \u0627\u0644\u062f\u0631\u0627\u0633\u0629 \u0644\u062a\u0643\u0648\u0646 \u062f\u0631\u0627\u0633\u0629 \u0627\u0633\u062a\u0628\u0627\u0642\u064a\u0629 \u0645\u0639\u0634\u0648\u0623\u0629 randomized prospective study\u060c \u0648\u062d\u0638\u064a\u062a \u0628\u0645\u0648\u0627\u0641\u0642\u0629 \u0644\u062c\u0646\u0629 \u0627\u0644\u0645\u0631\u0627\u062c\u0639\u0629 \u0627\u0644\u0639\u0644\u0645\u064a\u0629 \u0627\u0644\u0623\u062e\u0644\u0627\u0642\u064a\u0651\u0629 \u0641\u064a \u0643\u0644\u064a\u0629 \u0627\u0644\u0635\u064a\u062f\u0644\u0629 \u0628\u062c\u0627\u0645\u0639\u0629 \u062f\u0645\u0634\u0642. \u0623\u062c\u0631\u064a\u062a \u0627\u0644\u062f\u0651\u0631\u0627\u0633\u0629 \u0641\u064a \u0645\u0633\u062a\u0634\u0641\u064a\u064a \u0627\u0644\u0628\u064a\u0631\u0648\u0646\u064a \u0627\u0644\u062c\u0627\u0645\u0639\u064a \u0648\u0627\u0644\u0647\u0644\u0627\u0644 \u0627\u0644\u0623\u062d\u0645\u0631 \u0628\u062f\u0645\u0634\u0642\u060c \u0648\u0630\u0644\u0643 \u0641\u064a \u0627\u0644\u0641\u062a\u0631\u0629 \u0627\u0644\u0645\u0645\u062a\u062f\u0629 \u0628\u064a\u0646 \u0634\u0647\u0631 \u062d\u0632\u064a\u0631\u0627\u0646 2012 \u0625\u0644\u0649 \u0634\u0647\u0631 \u0627\u064a\u0644\u0648\u0644 2014. \u0634\u0645\u0644\u062a \u0645\u0639\u0627\u064a\u064a\u0631 \u0627\u0644\u0627\u0634\u062a\u0645\u0627\u0644 inclusion criteria \u0645\u0631\u064a\u0636\u0627\u062a \u0645\u0634\u062e\u0651\u0635\u0627\u062a \u0628\u0633\u0631\u0637\u0627\u0646 \u062b\u062f\u064a \u0644\u0627 \u0646\u0642\u064a\u0644\u064a \u0625\u064a\u062c\u0627\u0628\u064a \u0627\u0644\u0645\u0633\u062a\u0642\u0628\u0644\u0627 \u0627\u0644\u0647\u0631\u0645\u0648\u0646\u064a\u0651\u0629 \u0645\u0645\u0646 \u064a\u062a\u0644\u0642\u064a\u0646 \u0645\u0639\u0627\u0644\u062c\u0629 \u0628\u0645\u062b\u0628\u0637\u0627\u062a \u0627\u0644\u0623\u0631\u0648\u0645\u0627\u062a\u0627\u0632\u060c \u0633\u0648\u0627\u0621 \u0643\u0627\u0646\u062a \u0645\u0633\u0628\u0648\u0642\u0629 \u0623\u0645 \u063a\u064a\u0631 \u0645\u0633\u0628\u0648\u0642\u0629 \u0628\u0634\u0648\u0637 \u0639\u0644\u0627\u062c\u064a \u0645\u0646 \u0627\u0644\u062a\u0627\u0645\u0648\u0643\u0633\u064a\u0641\u064a\u0646 \u0634\u0631\u064a\u0637\u0629 \u062b\u0628\u0627\u062a \u0642\u064a\u0645 \u0627\u0644\u0648\u0627\u0635\u0645\u0627\u062a \u0627\u0644\u0648\u0631\u0645\u064a\u0629 \u0636\u0645\u0646 \u0627\u0644\u0645\u062c\u0627\u0644 \u0627\u0644\u0637\u0628\u064a\u0639\u064a \u0623\u062b\u0646\u0627\u0621 \u0641\u062a\u0631\u0629 \u0627\u0644\u062f\u0631\u0627\u0633\u0629\u060c \u0648\u0639\u062f\u0645 \u062d\u062f\u0648\u062b \u0646\u0642\u0627\u0626\u0644 \u0648\u0631\u0645\u064a\u0629 \u0645\u062b\u0628\u062a\u0629 \u0628\u0627\u0644\u0635\u0648\u0631 \u0627\u0644\u0634\u0639\u0627\u0639\u064a\u0629 \u0648\u0628\u0646\u062a\u0627\u0626\u062c \u0627\u064a\u0643\u0648 \u0627\u0644\u0628\u0637\u0646 \u0648\u0627\u0644\u062d\u0648\u0636 \u0648\u062a\u0642\u0631\u064a\u0631 \u0648\u0645\u0636\u0627\u0646 \u0627\u0644\u0639\u0638\u0627\u0645 \u0637\u0648\u0627\u0644 \u0641\u062a\u0631\u0629 \u0627\u0644\u062f\u0631\u0627\u0633\u0629. \u0628\u0639\u062f \u0627\u0644\u062d\u0635\u0648\u0644 \u0639\u0644\u0649 \u0627\u0644\u0645\u0648\u0627\u0641\u0642\u0629 \u0627\u0644\u0645\u0633\u062a\u0646\u064a\u0631\u0629 \u0645\u0646 \u0643\u0644\u0651 \u0645\u0631\u064a\u0636\u0629\u060c \u0623\u062c\u0631\u064a\u062a \u0645\u0642\u0627\u0628\u0644\u0627\u062a \u0634\u062e\u0635\u064a\u0629 \u0645\u0639 \u0627\u0644\u0645\u0631\u064a\u0636\u0627\u062a \u0648\u0641\u0642 \u0627\u0633\u062a\u0645\u0627\u0631\u0629 \u0634\u0645\u0644\u062a \u0628\u0646\u0648\u062f\u0647\u0627 \u0628\u064a\u0627\u0646\u0627\u062a \u062f\u064a\u0645\u0648\u063a\u0631\u0627\u0641\u064a\u0629 \u062a\u0636\u0645\u0651\u0646\u062a \u0643\u0644\u0627\u064b \u0645\u0646 \u0627\u0644\u0639\u0645\u0631 \u0648\u0627\u0644\u0637\u0648\u0644 \u0648\u0627\u0644\u0648\u0632\u0646 (\u0644\u062d\u0633\u0627\u0628 \u0645\u0646\u0633\u0628 \u0643\u062a\u0644\u0629 \u0627\u0644\u062c\u0633\u0645 BMI (\u0643\u063a\/\u06452<\/sup>)) \u0648\u0637\u0628\u064a\u0639\u0629 \u0627\u0644\u0645\u0644\u0628\u0633 \u0648\u0644\u0648\u0646 \u0627\u0644\u0628\u0634\u0631\u0629 \u0648\u0627\u0644\u0639\u0627\u062f\u0627\u062a \u0627\u0644\u063a\u0630\u0627\u0626\u064a\u0629 \u0648\u0627\u0644\u0639\u0627\u0645\u0629 \u0645\u0646 \u062d\u064a\u062b \u062a\u0646\u0627\u0648\u0644 \u0645\u0634\u062a\u0642\u0627\u062a \u0627\u0644\u0623\u0644\u0628\u0627\u0646 \u0648\u0627\u0644\u0628\u064a\u0636 \u0648\u0627\u0644\u062a\u062f\u062e\u064a\u0646 \u0648\u0627\u0633\u062a\u062e\u062f\u0627\u0645 \u0627\u0644\u0648\u0627\u0642\u064a\u0627\u062a \u0627\u0644\u0634\u0645\u0633\u064a\u0629 \u0648\u0645\u062f\u0629 \u0627\u0644\u062a\u0639\u0631\u0651\u0636 \u0627\u0644\u0648\u0633\u0637\u064a \u0627\u0644\u064a\u0648\u0645\u064a \u0644\u0623\u0634\u0639\u0629 \u0627\u0644\u0634\u0645\u0633. \u0643\u0645\u0627 \u0627\u0634\u062a\u0645\u0644\u062a \u0627\u0644\u0627\u0633\u062a\u0645\u0627\u0631\u0629 \u0639\u0644\u0649 \u0645\u0639\u0644\u0648\u0645\u0627\u062a \u062a\u062a\u0639\u0644\u0642 \u0628\u0633\u0646\u0651 \u0627\u0646\u0642\u0637\u0627\u0639 \u0627\u0644\u0637\u0645\u062b \u0644\u062f\u0649 \u0627\u0644\u0633\u064a\u062f\u0629 \u0648\u062a\u062d\u062f\u064a\u062f \u0623\u0633\u0628\u0627\u0628\u0647 \u0645\u0646 \u062d\u064a\u062b \u0643\u0648\u0646\u0647 \u0636\u0647\u064a\u0627\u064b \u0637\u0628\u064a\u0639\u064a\u0651\u0627\u064b \u0623\u0645 \u062c\u0631\u0627\u062d\u064a\u0627\u064b \u0623\u0645 \u062f\u0648\u0627\u0626\u064a\u0651\u0627\u064b \u0623\u0645 \u0634\u0639\u0627\u0639\u064a\u0651\u0627\u064b \u0623\u0645 \u0645\u062d\u0631\u0651\u0636\u0627\u064b \u0628\u0627\u0644\u062c\u0631\u0639\u0627\u062a \u0627\u0644\u0643\u064a\u0645\u064a\u0627\u0626\u064a\u0629\u060c \u0648\u0648\u062c\u0648\u062f \u0642\u0635\u0629 \u0639\u0627\u0626\u0644\u064a\u0629 \u0644\u0644\u0625\u0635\u0627\u0628\u0629 \u0628\u0627\u0644\u0633\u0631\u0637\u0627\u0646. \u0642\u064f\u062f\u0651\u0645\u062a \u0644\u0644\u0645\u0631\u064a\u0636\u0627\u062a \u0634\u0631\u0648\u062d\u0627\u062a \u0643\u0627\u0641\u064a\u0629 \u0639\u0646 \u0637\u0628\u064a\u0639\u0629 \u0627\u0644\u062f\u0651\u0631\u0627\u0633\u0629 \u0648\u0623\u0647\u0645\u064a\u0629 \u0627\u0644\u0645\u0642\u0627\u064a\u0633\u0627\u062a \u0627\u0644\u0634\u0639\u0627\u0639\u064a\u0629 \u0648\u0627\u0644\u0645\u062e\u0628\u0631\u064a\u0629 \u00a0\u0644\u062a\u062d\u0631\u064a \u0646\u0642\u0635 \u0627\u0644\u0643\u062b\u0627\u0641\u0629 \u0627\u0644\u0639\u0638\u0645\u064a\u0629 \u0627\u0644\u0645\u0635\u0627\u062d\u0628\u0629 \u0628\u0640 AIs\u060c \u0648\u0636\u0631\u0648\u0631\u0629 \u062a\u0644\u0642\u064a \u0645\u0639\u0627\u0644\u062c\u0629 \u062f\u0648\u0627\u0626\u064a\u0629 \u0644\u062a\u062c\u0646\u0628 \u062a\u0631\u0642\u064a \u0642\u0644\u0651\u0629 \u0623\u0648 \u062a\u062e\u0644\u062e\u0644 \u0627\u0644\u0639\u0638\u0627\u0645. \u0648\u0632\u0639\u062a \u0627\u0644\u0645\u0631\u064a\u0636\u0627\u062a \u0627\u0644\u0645\u0633\u062a\u0648\u0641\u064a\u0627\u062a \u0644\u0645\u0639\u0627\u064a\u064a\u0631 \u0627\u0644\u062a\u0651\u0636\u0645\u064a\u0646 \u0648\u0627\u0644\u0644\u0627\u062a\u064a \u0623\u0639\u0637\u064a\u0646 \u0645\u0648\u0627\u0641\u0642\u0627\u062a\u0647\u0646 \u0627\u0644\u0645\u0633\u062a\u0646\u064a\u0631\u0629 \u0628\u0637\u0631\u064a\u0642\u0629 \u0645\u0639\u0634\u0651\u0648\u0623\u0629 \u0641\u064a \u0645\u062c\u0645\u0648\u0639\u062a\u064a\u0646 (\u0630\u0631\u0627\u0639\u064a \u0627\u0644\u062f\u0651\u0631\u0627\u0633\u0629) \u062d\u064a\u062b \u062a\u0644\u0642\u062a \u0625\u062d\u062f\u0627\u0647\u0645\u0627 ]\u0641\u064a\u062a\u0627\u0645\u064a\u0646 D3<\/sub> \u0628\u062c\u0631\u0639\u0629 800 \u0648\u062d\u062f\u0629 \u062f\u0648\u0644\u064a\u0629 \u064a\u0648\u0645\u064a\u0651\u0627\u064b + \u0643\u0627\u0644\u0633\u064a\u0648\u0645 \u0639\u0646\u0635\u0631\u064a \u0628\u062c\u0631\u0639\u0629 1000 \u0645\u0644\u063a \u064a\u0648\u0645\u064a\u0627\u064b + \u0631\u064a\u0632\u064a\u062f\u0631\u0648\u0646\u0627\u062a 75 \u0645\u0644\u063a \u0644\u064a\u0648\u0645\u064a\u0646 \u0641\u064a \u0643\u0644 \u0634\u0647\u0631[\u060c \u0641\u064a \u062d\u064a\u0646 \u062a\u0644\u0642\u062a \u0645\u0631\u064a\u0636\u0627\u062a \u0627\u0644\u0645\u062c\u0645\u0648\u0639\u0629 \u0627\u0644\u062b\u0627\u0646\u064a\u0629 ]\u0641\u064a\u062a\u0627\u0645\u064a\u0646 D3<\/sub> \u0628\u062c\u0631\u0639\u0629 5800 \u0648\u062d\u062f\u0629 \u062f\u0648\u0644\u064a\u0629\/\u0627\u0644\u064a\u0648\u0645 + \u0643\u0627\u0644\u0633\u064a\u0648\u0645 \u0639\u0646\u0635\u0631\u064a \u0628\u062c\u0631\u0639\u0629 1000 \u0645\u0644\u063a \u064a\u0648\u0645\u064a\u0627\u064b + \u0631\u064a\u0632\u064a\u062f\u0631\u0648\u0646\u0627\u062a 75 \u0645\u0644\u063a \u0645\u0631\u062a\u064a\u0646 \u0643\u0644 \u0634\u0647\u0631[. \u0648\u0628\u0647\u0630\u0627\u060c \u0641\u0642\u062f \u0627\u0642\u062a\u0635\u0631 \u0627\u0644\u0627\u062e\u062a\u0644\u0627\u0641 \u0628\u064a\u0646 \u0627\u0644\u062e\u0637\u0651\u064a\u0646 \u0627\u0644\u0639\u0644\u0627\u062c\u064a\u064a\u0646 \u0639\u0644\u0649 \u0625\u0636\u0627\u0641\u0629 \u062c\u0631\u0639\u0629 5000 \u0648\u062d\u062f\u0629 \u062f\u0648\u0644\u064a\u0629 \u0645\u0646 \u0641\u064a\u062a\u0627\u0645\u064a\u0646 D3<\/sub>.<\/span><\/p>\n

\u0642\u064a\u0627\u0633 \u0627\u0644\u0643\u062b\u0627\u0641\u0629 \u0627\u0644\u0645\u0639\u062f\u0646\u064a\u0651\u0629 \u0627\u0644\u0639\u0638\u0645\u064a\u0651\u0629<\/strong><\/span><\/p>\n

\u00a0\u0642\u064a\u0633\u062a \u0627\u0644\u0643\u062b\u0627\u0641\u0629 \u0627\u0644\u0645\u0639\u062f\u0646\u064a\u0629 \u0644\u0644\u0639\u0638\u0645 \u0628\u0637\u0631\u064a\u0642\u0629 \u0642\u064a\u0627\u0633 \u0627\u0645\u062a\u0635\u0627\u0635 \u0627\u0644\u0623\u0634\u0639\u0629 \u0627\u0644\u0633\u064a\u0646\u064a\u0629 \u062b\u0646\u0627\u0626\u064a \u0627\u0644\u0628\u0648\u0627\u0639\u062b Dual-energy X-ray absorptiometry (DXA) \u0641\u064a \u0627\u0644\u0641\u0642\u0631\u0627\u062a \u0627\u0644\u0642\u0637\u0646\u064a\u0651\u0629 Lumbar Spine \u00a0[L2-L4]\u0648\u0639\u0646\u0642 \u0627\u0644\u0641\u062e\u0630 Femoral Neck \u0648\u062a\u0645\u0651 \u062a\u0635\u0646\u0651\u0641 \u062f\u0631\u062c\u0629 \u0627\u0644\u0643\u062b\u0627\u0641\u0629 \u0627\u0644\u0639\u0638\u0645\u064a\u0629 \u062a\u0628\u0639\u0627\u064b \u0644\u0645\u0639\u0627\u064a\u064a\u0631 \u0645\u0646\u0638\u0645\u0629 \u0627\u0644\u0635\u062d\u0629 \u0627\u0644\u0639\u0627\u0644\u0645\u064a\u0629 (WHO) \u0625\u0644\u0649 \u0643\u062b\u0627\u0641\u0629 \u0639\u0638\u0645\u064a\u0629 \u0637\u0628\u064a\u0639\u064a\u0629 \u0648\u0642\u0644\u0651\u0629 \u0643\u062b\u0627\u0641\u0629 \u0639\u0638\u0645\u064a\u0629 \u0648\u062a\u062e\u0644\u062e\u0644 \u0639\u0638\u0645\u064a<\/span><\/p>\n

\u0627\u0644\u0627\u0639\u062a\u064a\u0627\u0646 <\/strong>Sampling<\/strong><\/span><\/p>\n

\u0628\u0632\u0644\u064f 10 \u0645\u0644 \u0645\u0646 \u0627\u0644\u062f\u0645 \u0627\u0644\u0648\u0631\u064a\u062f\u064a \u0644\u0643\u0644 \u0645\u0631\u064a\u0636\u0629 \u0645\u0634\u0627\u0631\u0643\u0629 \u0641\u064a \u0627\u0644\u062f\u0631\u0627\u0633\u0629 \u0625\u0644\u0649 \u0623\u0646\u0628\u0648\u0628 \u0632\u062c\u0627\u062c\u064a \u062c\u0627\u0641 \u0628\u0647\u062f\u0641 \u0625\u062c\u0631\u0627\u0621 \u0627\u0644\u0645\u0642\u0627\u064a\u0633\u0627\u062a \u0627\u0644\u0643\u064a\u0645\u064a\u0627\u0626\u064a\u0629 \u0627\u0644\u062d\u064a\u0648\u064a\u0629 \u0648\u0627\u0644\u0647\u0631\u0645\u0648\u0646\u064a\u0651\u0629\u060c \u0648\u0627\u0644\u062a\u064a \u0634\u0645\u0644\u062a \u0643\u0644\u0627\u064b \u0645\u0646 \u0627\u0644\u0641\u0648\u0633\u0641\u0648\u0631 \u0648\u0627\u0644\u0643\u0627\u0644\u0633\u064a\u0648\u0645 \u0648\u0627\u0644\u0628\u0648\u0644\u0629 \u0648\u0627\u0644\u0643\u0631\u064a\u0627\u062a\u064a\u0646\u064a\u0646 \u0648\u0627\u0644\u0641\u0648\u0633\u0641\u0627\u062a\u0627\u0632 \u0627\u0644\u0642\u0644\u0648\u064a\u0629 \u064825(OH)D \u0648\u062c\u0627\u0631\u0627\u062a \u0627\u0644\u062f\u0631\u0642 (PTH) \u0648\u0627\u0644\u0627\u0648\u0633\u062a\u064a\u0648\u0643\u0627\u0644\u0633\u064a\u0646 Osteocalcin (OC).<\/span><\/p>\n

\u0627\u0644\u0645\u0642\u0627\u064a\u0633\u0627\u062a \u0627\u0644\u0643\u064a\u0645\u064a\u0627\u0626\u064a\u0629 \u0627\u0644\u062d\u064a\u0648\u064a\u0629 \u0648\u0627\u0644\u0647\u0631\u0645\u0648\u0646\u064a\u0651\u0629<\/strong><\/span><\/p>\n

\u0623\u062c\u0631\u064a\u062a \u0645\u0642\u0627\u064a\u0633\u0629 (25(OH)D) \u0628\u0627\u0633\u062a\u0639\u0645\u0627\u0644 \u062c\u0647\u0627\u0632 (Elecsyse10\/20) \u0641\u064a \u0645\u0633\u062a\u0634\u0641\u0649 \u0627\u0644\u0623\u0633\u062f \u0627\u0644\u062c\u0627\u0645\u0639\u064a. \u0641\u064a \u062d\u064a\u0646 \u0623\u062c\u0631\u064a\u062a \u062c\u0645\u064a\u0639 \u0627\u0644\u0645\u0642\u0627\u064a\u0633\u0627\u062a \u0627\u0644\u0623\u062e\u0631\u0649 \u0641\u064a \u0645\u0633\u062a\u0634\u0641\u0649 \u0627\u0644\u0628\u064a\u0631\u0648\u0646\u064a \u0627\u0644\u062c\u0627\u0645\u0639\u064a\u060c \u062d\u064a\u062b \u0642\u064a\u0633\u062a \u062a\u0631\u0627\u0643\u064a\u0632 \u0643\u0644\u0651\u064d \u0645\u0646 \u0627\u0644\u0641\u0648\u0633\u0641\u0648\u0631 \u0648\u0627\u0644\u0643\u0627\u0644\u0633\u064a\u0648\u0645 \u0648\u0627\u0644\u0628\u0648\u0644\u0629 \u0648\u0627\u0644\u0643\u0631\u064a\u0627\u062a\u064a\u0646\u064a\u0646 \u0648\u0627\u0644\u0641\u0648\u0633\u0641\u0627\u062a\u0627\u0632 \u0627\u0644\u0642\u0644\u0648\u064a\u0629 \u0622\u0644\u064a\u0651\u0627\u064b \u0628\u0627\u0633\u062a\u0639\u0645\u0627\u0644 \u062c\u0647\u0627\u0632 (PS400)\u060c \u0623\u0645\u0651\u0627 \u0645\u0642\u0627\u064a\u0633\u0627\u062a \u0643\u0644\u0651\u064d \u0645\u0646 \u0627\u0644\u0640 PTH \u0648\u0627\u0644\u0627\u0648\u0633\u064a\u062a\u0648\u0643\u0627\u0644\u0633\u064a\u0646 \u0641\u0623\u062c\u0631\u064a\u062a \u0628\u0627\u0633\u062a\u0639\u0645\u0627\u0644 \u062c\u0647\u0627\u0632 (IMMULITE 2000).<\/span><\/p>\n

\u0627\u0644\u062a\u0651\u062d\u0644\u064a\u0644 \u0627\u0644\u0625\u062d\u0635\u0627\u0626\u064a\u0651<\/strong><\/span><\/p>\n

\u062d\u064f\u0644\u0651\u0644\u062a \u0627\u0644\u0628\u064a\u0627\u0646\u0627\u062a \u0625\u062d\u0635\u0627\u0626\u064a\u0651\u0627\u064b\u00a0 \u0628\u0627\u0633\u062a\u0639\u0645\u0627\u0644 \u0628\u0631\u0646\u0627\u0645\u062c IBM SPSS Statistics 20 \u0648\u062a\u0637\u0628\u064a\u0642 \u0627\u062e\u062a\u0628\u0627\u0631 Kolmogorov-Smirnova<\/sup> \/Shapiro-Wilk \u0644\u0644\u062a\u062d\u0642\u0651\u0642 \u0645\u0646 \u062a\u0648\u0632\u0651\u0639 \u0627\u0644\u0628\u064a\u0627\u0646\u0627\u062a \u062a\u0648\u0632\u0651\u0639\u0627\u064b \u0637\u0628\u064a\u0639\u064a\u0651\u0627\u064b \u0644\u0625\u062c\u0631\u0627\u0621 \u0627\u062e\u062a\u0628\u0627\u0631\u064a T-test\u00a0 \u0648\u0627\u062e\u062a\u0628\u0627\u0631 One Way ANOVA \u0644\u0644\u0645\u0645\u064a\u0632\u0627\u062a \u0627\u0644\u0639\u0627\u0645\u0629 \u0648\u0627\u0644\u062f\u064a\u0645\u0648\u063a\u0631\u0627\u0641\u064a\u0629 \u0648\u0644\u0644\u0645\u062a\u063a\u064a\u0631\u0627\u062a (T-Score, Z-Score, BMD) \u0644\u0644\u0641\u0642\u0631\u0627\u062a \u0627\u0644\u0642\u0637\u0646\u064a\u0629 \u0648\u0639\u0646\u0642 \u0627\u0644\u0641\u062e\u062f<\/span><\/p>\n

\u0627\u0644\u0646\u062a\u0627\u0626\u062c <\/strong>Results<\/strong><\/span><\/p>\n

\u0642\u0645\u0646\u0627 \u0628\u0625\u062c\u0631\u0627\u0621 \u0645\u0642\u0627\u0628\u0644\u0627\u062a \u0645\u0639 155 \u0645\u0631\u064a\u0636\u0629 \u0645\u0634\u062e\u0651\u0635\u0629 \u0628\u0633\u0631\u0637\u0627\u0646 \u062b\u062f\u064a \u0644\u0627 \u0646\u0642\u064a\u0644\u064a \u0644\u062a\u0642\u064a\u064a\u0645 \u062a\u062d\u0642\u064a\u0642\u0647\u0646\u0651 \u0644\u0645\u0639\u0627\u064a\u064a\u0631 \u0627\u0644\u062a\u0651\u0636\u0645\u064a\u0646 \u0648\u0627\u0644\u062d\u0635\u0648\u0644 \u0639\u0644\u0649 \u0645\u0648\u0627\u0641\u0642\u0627\u062a\u0647\u0646\u0651 \u0627\u0644\u0645\u0633\u062a\u0646\u064a\u0631\u0629. \u0631\u0641\u0636\u062a 33 \u0645\u0631\u064a\u0636\u0629 \u0627\u0644\u0645\u0634\u0627\u0631\u0643\u0629 \u0641\u064a \u0627\u0644\u062f\u0631\u0627\u0633\u0629 \u0644\u0623\u0633\u0628\u0627\u0628 \u062a\u062a\u0639\u0644\u0642 \u0628\u0639\u062f\u0645 \u0642\u0628\u0648\u0644 \u0627\u0644\u0632\u0648\u062c \u0623\u0648 \u0627\u0644\u0623\u0647\u0644 \u0623\u0648 \u0631\u0641\u0636\u0647\u0646\u0651 \u0627\u0639\u0637\u0627\u0621 \u0645\u0639\u0644\u0648\u0645\u0627\u062a \u0634\u062e\u0635\u064a\u0629\u060c \u0623\u0648 \u0644\u062a\u062e\u0648\u0641\u0647\u0646\u0651 \u0645\u0646 \u0627\u0644\u0627\u0646\u062e\u0631\u0627\u0637 \u0641\u064a \u0628\u062d\u062b \u0639\u0644\u0645\u064a \u0623\u0648 \u062f\u0631\u0627\u0633\u0629 \u0633\u0631\u064a\u0631\u064a\u0629 \u0623\u0648 \u0628\u0633\u0628\u0628 \u0627\u0644\u062e\u0648\u0641 \u0645\u0646 \u0628\u0632\u0644 \u0627\u0644\u062f\u0645 \u0623\u0648 \u0639\u062f\u0645 \u0642\u062f\u0631\u062a\u0647\u0646\u0651 \u0639\u0644\u0649 \u0627\u0644\u0627\u0644\u062a\u0632\u0627\u0645 \u0628\u0645\u062a\u0637\u0644\u0628\u0627\u062a \u0627\u0644\u062f\u0651\u0631\u0627\u0633\u0629. \u0643\u0645\u0627 \u0627\u0633\u062a\u0628\u0639\u062f\u062a 28 \u0645\u0631\u064a\u0636\u0629 \u0623\u062e\u0631\u0649 \u0644\u0639\u062f\u0645 \u062a\u0648\u0641\u0631 Exemesten \u0623\u0648 Anastrazole \u0623\u0648 letrozol \u062e\u0644\u0627\u0644 \u0627\u0644\u0641\u062a\u0631\u0629 \u0627\u0644\u0645\u0645\u062a\u062f\u0629 \u0628\u064a\u0646 \u0643\u0627\u0646\u0648\u0646 \u0627\u0644\u062b\u0627\u0646\u064a 2013 \u0625\u0644\u0649 \u062a\u0645\u0648\u0632 \u0645\u0646 \u0627\u0644\u0639\u0627\u0645 \u0630\u0627\u062a\u0647 \u0641\u064a \u0645\u0633\u062a\u0634\u0641\u0649 \u0627\u0644\u0628\u064a\u0631\u0648\u0646\u064a \u0627\u0644\u062c\u0627\u0645\u0639\u064a\u060c \u062d\u064a\u062b \u062d\u0648\u0651\u0644\u062a \u0627\u0644\u0633\u064a\u062f\u0627\u062a \u0625\u0644\u0649 \u0627\u0644\u0639\u0644\u0627\u062c \u0628\u0627\u0644\u062a\u0627\u0645\u0648\u0643\u0633\u064a\u0641\u064a\u0646 \u0628\u062f\u064a\u0644\u0627\u064b \u0639\u0646\u0647. \u062a\u0645 \u0627\u0633\u062a\u0628\u0639\u0627\u062f 17 \u0645\u0631\u064a\u0636\u0629 \u0628\u0633\u0628\u0628 \u062a\u0631\u0642\u064a \u0627\u0644\u0645\u0631\u0636 \u0648\u0638\u0647\u0648\u0631 \u0646\u0642\u0627\u0626\u0644 (\u0643\u0628\u062f\u064a\u0629 \u0648\/\u0623\u0648 \u0639\u0638\u0645\u064a\u0629 \u0648\/\u0623\u0648 \u062f\u0645\u0627\u063a\u064a\u0629 \u0648\/\u0623\u0648 \u0631\u0626\u0648\u064a\u0629) \u062e\u0644\u0627\u0644 \u0641\u062a\u0631\u0629 \u0627\u0644\u062f\u0631\u0627\u0633\u0629\u060c \u0643\u0645\u0627 \u0627\u0633\u062a\u0628\u0639\u062f\u062a 17 \u0645\u0631\u064a\u0636\u0629 \u0644\u0639\u062f\u0645 \u0627\u0644\u062a\u0632\u0627\u0645\u0647\u0646 \u0628\u0627\u0644\u062e\u0637 \u0627\u0644\u0639\u0644\u0627\u062c\u064a \u0623\u0648 \u0628\u0633\u0628\u0628 \u062a\u063a\u064a\u064a\u0631 \u0627\u0644\u062c\u0631\u0639\u0629 \u0628\u0634\u0643\u0644 \u0634\u062e\u0635\u064a \u0623\u0648 \u0645\u0646 \u0642\u0628\u0644 \u0637\u0628\u064a\u0628 \u0622\u062e\u0631 \u062e\u0627\u0631\u062c \u0645\u0633\u062a\u0634\u0641\u0649 \u0627\u0644\u0628\u064a\u0631\u0648\u0646\u064a \u0623\u0648 \u0645\u0633\u062a\u0634\u0641\u0649 \u0627\u0644\u0647\u0644\u0627\u0644 \u0627\u0644\u0623\u062d\u0645\u0631. \u062a\u0645 \u0627\u0633\u062a\u0628\u0639\u0627\u062f 12 \u0645\u0631\u064a\u0636\u0629 \u0644\u0641\u0642\u062f\u0627\u0646 \u0627\u0644\u062a\u0648\u0627\u0635\u0644 \u0628\u0633\u0628\u0628 \u0627\u0644\u0646\u0632\u0648\u062d \u0623\u0648 \u0627\u0644\u0648\u0641\u0627\u0629 <\/span>\u0623\u0648 \u0635\u0639\u0648\u0628\u0629 \u0627\u0644\u0648\u0635\u0648\u0644 \u0644\u0644\u0645\u0633\u062a\u0634\u0641\u0649\u060c \u0648\u0628\u0647\u0630\u0627 \u0628\u0644\u063a \u0639\u062f\u062f \u0627\u0644\u0645\u0631\u064a\u0636\u0627\u062a \u0627\u0644\u0645\u0633\u062a\u0628\u0639\u062f\u0627\u062a \u0645\u0646 \u0627\u0644\u062f\u0631\u0627\u0633\u0629 \u0644\u062c\u0645\u064a\u0639 \u0627\u0644\u0623\u0633\u0628\u0627\u0628 \u0627\u0644\u0622\u0646\u0641 \u0630\u0643\u0631\u0647\u0627 107 \u0645\u0631\u064a\u0636\u0629. \u0628\u0644\u063a \u0639\u062f\u062f \u0627\u0644\u0645\u0631\u064a\u0636\u0627\u062a \u0627\u0644\u0645\u0634\u0645\u0648\u0644\u0627\u062a \u0641\u064a \u0627\u0644\u062f\u0631\u0627\u0633\u0629 \u0648\u0627\u0644\u0644\u0627\u062a\u064a <\/span>\u0623\u062c\u0631\u064a\u062a \u0644\u0647\u0646 \u0627\u0644\u0645\u0642\u0627\u064a\u0633\u0627\u062a \u0627\u0644\u0643\u064a\u0645\u064a\u0627\u0626\u064a\u0629 \u0627\u0644\u062d\u064a\u0648\u064a\u0629 \u0648\u0627\u0644\u0647\u0631\u0645\u0648\u0646\u064a\u0629 \u0648\u0627\u0644\u0634\u0639\u0627\u0639\u064a\u0629 \u0648\u0627\u0644\u062a\u0632\u0645\u0646 \u0628\u0627\u0644\u062e\u0637 \u0627\u0644\u0639\u0644\u0627\u062c\u064a 48 \u0645\u0631\u064a\u0636\u0629\u060c \u062d\u064a\u062b \u0628\u0644\u063a \u0639\u062f\u062f \u0627\u0644\u0645\u0631\u064a\u0636\u0627\u062a \u0627\u0644\u0644\u0648\u0627\u062a\u064a \u0627\u0644\u062a\u0632\u0645\u0646 \u0628\u0627\u0644\u062e\u0637 \u0627\u0644\u0639\u0644\u0627\u062c\u064a \u0627\u0644\u0623\u0648\u0644 (D800<\/sub>) 23 \u0645\u0631\u064a\u0636\u0629\u060c \u0641\u064a \u062d\u064a\u0646 \u0628\u0644\u063a \u0639\u062f\u062f \u0627\u0644\u0645\u0631\u064a\u0636\u0627\u062a \u0627\u0644\u0644\u0648\u0627\u062a\u064a \u0627\u0644\u062a\u0632\u0645\u0646 \u0628\u0627\u0644\u062e\u0637 \u0627\u0644\u0639\u0644\u0627\u062c\u064a \u0627\u0644\u062b\u0627\u0646\u064a (D5800<\/sub>) 25 \u0645\u0631\u064a\u0636\u0629. \u062a\u0641\u0627\u0648\u062a\u062a \u0645\u062f\u0651\u0629 \u0627\u0644\u062a\u0632\u0627\u0645 \u0627\u0644\u0645\u0631\u064a\u0636\u0627\u062a \u0628\u0627\u0644\u0625\u0637\u0627\u0631 \u0627\u0644\u0632\u0645\u0646\u064a \u0644\u0644\u062e\u0637 \u0627\u0644\u0639\u0644\u0627\u062c\u064a \u0627\u0644\u0645\u0639\u0637\u0649 \u0645\u0646 3 \u0625\u0644\u0649 11 \u0634\u0647\u0631\u0627\u064b\u060c \u062d\u064a\u062b \u0628\u0644\u063a \u0639\u062f\u062f \u0627\u0644\u0645\u0631\u064a\u0636\u0627\u062a \u0627\u0644\u0644\u0648\u0627\u062a\u064a \u0627\u0644\u062a\u0632\u0645\u0646 \u0645\u062f\u0629 \u2264 6 \u0623\u0634\u0647\u0631 \u0641\u064a \u0627\u0644\u062e\u0637 \u0627\u0644\u0639\u0644\u0627\u062c\u064a \u0627\u0644\u0623\u0648\u0644 (6\u2265D800<\/sub>) 10 \u0645\u0631\u064a\u0636\u0627\u062a \u0645\u0646 \u0623\u0635\u0644 23 \u0645\u0631\u064a\u0636\u0629 (43.5%) \u0645\u0642\u0627\u0628\u0644 13 \u0645\u0631\u064a\u0636\u0629 \u0627\u0644\u062a\u0632\u0645\u0646 \u0645\u062f\u0629 < 6 \u0623\u0634\u0647\u0631 (D800<\/sub>>6)<\/strong>. \u0648\u0628\u0627\u0644\u0645\u0642\u0627\u0628\u0644\u060c \u0627\u0644\u062a\u0632\u0645\u062a 10 \u0645\u0631\u064a\u0636\u0627\u062a \u0645\u0646 \u0623\u0635\u0644 25 \u0645\u0631\u064a\u0636\u0629 (40%) \u0628\u0627\u0644\u062e\u0637 \u0627\u0644\u0639\u0644\u0627\u062c\u064a \u0627\u0644\u062b\u0627\u0646\u064a \u0645\u062f\u0629 \u2264 6 \u0623\u0634\u0647\u0631 (6\u2265D5800<\/sub>)\u060c \u0641\u064a \u062d\u064a\u0646 \u0627\u0644\u062a\u0632\u0645\u062a 15 ((60% \u0645\u0631\u064a\u0636\u0629 \u0645\u062f\u0629 < 6 \u0623\u0634\u0647\u0631 (D5800<\/sub>>6).<\/span><\/p>\n

\u0627\u0644\u062e\u0635\u0627\u0626\u0635 \u0627\u0644\u0639\u0627\u0645\u0629 \u0648\u0627\u0644\u062f\u064a\u0645\u0648\u063a\u0631\u0627\u0641\u064a\u0629 \u0644\u0644\u0645\u0631\u064a\u0636\u0627\u062a \u0627\u0644\u0645\u0634\u0627\u0631\u0643\u0627\u062a \u0641\u064a \u0627\u0644\u062f\u0651\u0631\u0627\u0633\u0629<\/strong><\/span><\/p>\n

\u064a\u0644\u062e\u0651\u0635 \u0627\u0644\u062c\u062f\u0648\u0644 (1) \u0627\u0644\u062e\u0635\u0627\u0626\u0635 \u0627\u0644\u0639\u0627\u0645\u0629 \u0648\u0627\u0644\u062f\u064a\u0645\u0648\u063a\u0631\u0627\u0641\u064a\u0629 \u0644\u0644\u0645\u0634\u0627\u0631\u0643\u0627\u062a \u0628\u0627\u0644\u062f\u0631\u0627\u0633\u0629\u060c \u062d\u064a\u062b \u064a\u062a\u0636\u062d \u0639\u062f\u0645 \u0648\u062c\u0648\u062f \u0641\u0648\u0627\u0631\u0642 \u0630\u0627\u062a \u062f\u0644\u0627\u0644\u0629 \u0625\u062d\u0635\u0627\u0626\u064a\u0651\u0629 (P>0.05) \u0628\u064a\u0646 \u0630\u0631\u0627\u0639\u064a\u0651 \u0627\u0644\u062f\u0651\u0631\u0627\u0633\u0629 \u0641\u064a \u062c\u0645\u064a\u0639 \u0627\u0644\u0645\u0642\u0627\u0631\u0646\u0627\u062a \u0627\u0644\u062a\u064a \u0639\u064f\u0642\u062f\u062a\u061b \u0648\u0630\u0644\u0643 \u0645\u0646 \u062d\u064a\u062b \u0627\u0644\u0639\u0645\u0631 \u0648\u0627\u0644\u0640 BMI \u0648\u0627\u0644\u062a\u062f\u062e\u064a\u0646 \u0648\u0644\u0648\u0646 \u0627\u0644\u0628\u0634\u0631\u0629 \u0648\u0637\u0628\u064a\u0639\u0629 \u0627\u0644\u0645\u0644\u0628\u0633 \u0648\u0645\u062f\u0629 \u0627\u0644\u062a\u0639\u0631\u0636 \u0644\u0623\u0634\u0639\u0629 \u0627\u0644\u0634\u0645\u0633 \u0648\u062a\u0646\u0627\u0648\u0644 \u0645\u0634\u062a\u0642\u0627\u062a \u0627\u0644\u0623\u0644\u0628\u0627\u0646 \u0648\u0627\u0644\u0628\u064a\u0636 \u0648\u0627\u0644\u0645\u062a\u0645\u0645\u0651\u0627\u062a (\u0627\u0644\u0643\u0627\u0644\u0633\u064a\u0648\u0645 \u0648\u0641\u064a\u062a\u0627\u0645\u064a\u0646 (D3 <\/sub>\u0648\u0627\u0642\u062a\u0635\u0631 \u0627\u0644\u0641\u0627\u0631\u0642 \u0627\u0644\u0625\u062d\u0635\u0627\u0626\u064a \u0627\u0644\u0645\u0639\u062a\u062f \u0628\u0647 (0.03P=) \u0628\u064a\u0646 \u0627\u0644\u0645\u062c\u0645\u0648\u0639\u062a\u064a\u0646 \u0639\u0644\u0649 \u0645\u062a\u0648\u0633\u0637 \u0642\u064a\u0645 \u0627\u0644\u0640 ((BMI (\u0643\u063a\/\u06452) (\u0627\u0644\u062c\u062f\u0648\u0644 1).<\/span><\/p>\n

\u062f\u0631\u0627\u0633\u0629 \u0627\u0646\u062a\u0634\u0627\u0631 \u0642\u0644\u0629 \u0627\u0644\u0639\u0638\u0645 \u0623\u0648 \u0647\u0634\u0627\u0634\u062a\u0647 \u0644\u062f\u0649 \u0627\u0644\u0645\u0634\u0627\u0631\u0643\u0627\u062a \u0641\u064a \u0627\u0644\u062f\u0631\u0627\u0633\u0629<\/strong><\/span><\/p>\n

\u0628\u0644\u063a \u0639\u062f\u062f \u0627\u0644\u0645\u0631\u064a\u0636\u0627\u062a \u0637\u0628\u064a\u0639\u064a\u0627\u062a \u0627\u0644\u0643\u062b\u0627\u0641\u0629 \u0627\u0644\u0639\u0638\u0645\u064a\u0629 \u0623\u0631\u0628\u0639 \u0645\u0631\u064a\u0636\u0627\u062a \u0641\u0642\u0637 \u0648\u0628\u0646\u0633\u0628\u0629 \u0648\u0642\u062f\u0631\u0647\u0627 8.3% <\/strong>\u0645\u0646 \u0625\u062c\u0645\u0627\u0644\u064a \u0627\u0644\u0645\u0631\u064a\u0636\u0627\u062a\u060c \u0641\u064a \u062d\u064a\u0646 \u0643\u0627\u0646\u062a \u063a\u0627\u0644\u0628\u064a\u0651\u0629 \u0627\u0644\u0645\u0631\u064a\u0636\u0627\u062a (<\/strong>n=44\u060c 91.7%) <\/strong>\u064a\u0639\u0627\u0646\u064a\u0646 \u0645\u0646 \u062a\u062e\u0644\u062e\u0644 \u0627\u0644\u0639\u0638\u0627\u0645 \u0623\u0648 \u0642\u0644\u0651\u062a\u0647\u060c \u062a\u0648\u0632\u0639\u0646 \u0628\u064a\u0646 \u062a\u062e\u0644\u062e\u0644 \u0639\u0638\u0645 (n=10\u060c 20.9%)<\/strong> \u00a0\u0623\u0648 \u0642\u0644\u0651\u062a\u0647 (n=34\u060c 70.8%)<\/strong>.<\/span><\/p>\n

\"\"<\/span><\/p>\n

\u062f\u0631\u0627\u0633\u0629<\/strong> \u0627\u0646\u062a\u0634\u0627\u0631<\/strong> \u062f\u0631\u062c\u0629<\/strong> \u0646\u0642\u0635<\/strong> \u0641\u064a\u062a\u0627\u0645\u064a\u0646<\/strong> D3<\/sub><\/strong> \u0623\u0648<\/strong> \u0639\u0648\u0632\u0647<\/strong><\/span><\/p>\n

\u0644\u062f\u0649 \u062a\u0635\u0646\u064a\u0641 \u0645\u0631\u064a\u0636\u0627\u062a \u0627\u0644\u062f\u0651\u0631\u0627\u0633\u0629 \u0627\u0644\u0645\u0639\u0627\u0644\u062c\u0627\u062a \u0628\u0640 AIs \u062d\u0633\u0628 \u0645\u0639\u0627\u064a\u064a\u0631 IOM\u060c \u0627\u0642\u062a\u0635\u0631\u062a \u062d\u0627\u0644\u0629 \u0643\u0641\u0627\u064a\u0629 \u0627\u0644\u0641\u064a\u062a\u0627\u0645\u064a\u0646 D3<\/sub> (\u2265 20 \u0646\u063a\/\u0645\u0644) \u0639\u0644\u0649 \u062b\u0645\u0627\u0646\u064a \u0645\u0631\u064a\u0636\u0627\u062a \u0641\u062d\u0633\u0628\u060c \u0648\u0628\u0646\u0633\u0628\u0629\u064d \u0642\u062f\u0631\u0647\u0627 16.6%\u060c \u0641\u064a \u062d\u064a\u0646 \u0628\u0644\u063a \u0639\u062f\u062f \u0627\u0644\u0645\u0631\u064a\u0636\u0627\u062a \u0627\u0644\u0644\u0648\u0627\u062a\u064a \u0634\u062e\u0635\u0646 \u0628\u0639\u062f\u0645 \u0643\u0641\u0627\u064a\u0629 \u0641\u064a\u062a\u0627\u0645\u064a\u0646 D3<\/sub> 40 \u0645\u0631\u064a\u0636\u0629 \u062a\u0648\u0632\u0639\u0646 \u0628\u064a\u0646 \u0642\u0644\u0651\u0629 VitD3<\/sub> (n=14) \u0623\u0648 \u0639\u0648\u0632\u0647 (n=26) \u0645\u0631\u064a\u0636\u0629\u060c \u0648\u0628\u0646\u0633\u0628\u0629 \u0643\u0644\u064a\u0651\u0629\u064d \u0648\u0635\u0644\u062a \u0625\u0644\u0649 83.4% \u0645\u0646 \u0645\u062c\u0645\u0644 \u0627\u0644\u0645\u0631\u064a\u0636\u0627\u062a. \u00a0<\/strong>\u0648\u0628\u0627\u0633\u062a\u062b\u0646\u0627\u0621 \u0645\u0631\u064a\u0636\u0629 \u0648\u0627\u062d\u062f\u0629 \u0641\u0642\u0637\u060c \u0641\u0642\u062f \u0643\u0627\u0646\u062a \u0627\u0644\u063a\u0627\u0644\u0628\u064a\u0651\u0629 \u0627\u0644\u0639\u0638\u0645\u0649 \u0645\u0646 \u0627\u0644\u0645\u0631\u064a\u0636\u0627\u062a (<\/strong>n=47<\/strong>\u060c <\/strong>97.9%<\/strong>)<\/strong> \u062f\u0648\u0646 \u0627\u0644\u0642\u064a\u0645 \u0627\u0644\u0645\u0648\u0635\u0649 \u0628\u062a\u062d\u0642\u064a\u0642\u0647\u0627 (30-40<\/strong> \u0646\u063a\/\u0645\u0644) \u0645\u0646 \u062a\u0631\u0627\u0643\u064a\u0632 25(OH)D \u0644\u0644\u0648\u0642\u0627\u064a\u0629 \u0645\u0646 \u062e\u0633\u0627\u0631\u0629 \u0627\u0644\u0639\u0638\u0645 \u0627\u0644\u0645\u0635\u0627\u062d\u0628\u0629 \u0644\u0640 AIs.<\/span><\/p>\n

\u062a\u0623\u062b\u064a\u0631 \u0627\u0633\u062a\u0639\u0645\u0627\u0644 <\/strong>AIs<\/strong> \u0641\u064a \u0642\u064a\u0645<\/strong> (<\/strong>Z-Score<\/strong>\u060c <\/strong>T-Score<\/strong>\u060c <\/strong>BMD<\/strong>) \u0642\u0628\u0644 \u0627\u0644\u0645\u0628\u0627\u0634\u0631\u0629 \u0628\u0627\u0644\u0639\u0644\u0627\u062c <\/strong><\/span><\/p>\n

\u0643\u0627\u0646 \u0627\u0644\u0645\u062a\u0648\u0633\u0637 \u0627\u0644\u062d\u0633\u0627\u0628\u064a \u0644\u0642\u064a\u0645 T-Score \u0644\u0644\u0641\u0642\u0631\u0627\u062a \u0627\u0644\u0642\u0637\u0646\u064a\u0629 \u0644\u0644\u0645\u0631\u064a\u0636\u0627\u062a \u0642\u0628\u064a\u0644 \u0627\u0644\u0628\u062f\u0621 \u0628\u0627\u0644\u0645\u0639\u0627\u0644\u062c\u0629 \u0628\u0640 AIs [1.45- \u00b1 0.63]\u060c \u0648\u062a\u0646\u0627\u0642\u0635\u062a \u0642\u064a\u0645 \u0627\u0644\u0640 T-Score \u0647\u0630\u0647 \u0645\u0639\u0628\u0651\u0631\u0627\u064b \u0639\u0646\u0647\u0627 \u0628\u0627\u0644\u0645\u062a\u0648\u0633\u0637 \u0627\u0644\u062d\u0633\u0627\u0628\u064a \u0644\u0644\u0645\u0631\u064a\u0636\u0627\u062a \u0639\u0642\u0628 \u0627\u0633\u062a\u062e\u062f\u0645\u0647\u0646 \u0644\u0640 AIs (40 \u0645\u0631\u064a\u0636\u0629) \u0644\u062a\u0635\u0644 \u0625\u0644\u0649 [1.94- \u00b1 0.73]\u060c \u0648\u0628\u0641\u0627\u0631\u0642 \u0630\u064a \u062f\u0644\u0627\u0644\u0629\u064d \u0625\u062d\u0635\u0627\u0626\u064a\u0651\u0629 (P<\/em><\/strong>= 0.048). \u063a\u064a\u0631 \u0623\u0646\u0651 \u0627\u0644\u0641\u0627\u0631\u0642 \u0644\u0645 \u064a\u0643\u0646 \u0630\u0627 \u062f\u0644\u0627\u0644\u0629\u064d \u0625\u062d\u0635\u0627\u0626\u064a\u0651\u0629 \u0628\u0627\u0644\u0646\u0651\u0633\u0628\u0629 \u0644\u0640 Z-Score \u0648BMD (P<\/em><\/strong>= 0.321\u00a0 \u0648 P<\/em><\/strong>= 0.083\u060c \u0639\u0644\u0649 \u0627\u0644\u062a\u0651\u0631\u062a\u064a\u0628).<\/span><\/p>\n

\u0645\u0642\u0627\u0631\u0646\u0629 \u0627\u0644\u0645\u062a\u0648\u0633\u0637\u0627\u062a \u0627\u0644\u062d\u0633\u0627\u0628\u064a\u0629 \u0644\u0642\u064a\u0645\u0629<\/strong> 25(OH)D<\/strong> \u062a\u0628\u0639\u0627\u064b<\/strong> \u0644\u0645\u062f\u0629 \u0627\u0633\u062a\u062e\u062f\u0627\u0645 <\/strong>AIs<\/strong><\/span><\/p>\n

\u0643\u0627\u0646 \u0627\u0644\u0645\u062a\u0648\u0633\u0637 \u0627\u0644\u062d\u0633\u0627\u0628\u064a \u0644\u0642\u064a\u0645 25(OH)D<\/strong> \u0644\u0644\u0645\u0631\u064a\u0636\u0627\u062a \u0642\u0628\u064a\u0644 \u0627\u0644\u0628\u062f\u0621 \u0628\u0627\u0633\u062a\u062e\u062f\u0627\u0645 AIs [13.5<\/strong> \u00b1<\/strong>7.47<\/strong> \u0646\u063a\/\u0645\u0644]\u060c \u0641\u064a \u062d\u064a\u0646 \u0628\u0644\u063a \u0627\u0644\u0645\u062a\u0648\u0633\u0637 \u0627\u0644\u062d\u0633\u0627\u0628\u064a \u0644\u0644\u0645\u0631\u064a\u0636\u0627\u062a \u0627\u0644\u0644\u0627\u062a\u064a \u062a\u0644\u0642\u064a\u0646 \u0645\u0639\u0627\u0644\u062c\u0629 \u0628\u0640 AIs [9.99<\/strong> \u00b1<\/strong>5.95<\/strong> \u0646\u063a\/\u0645\u0644]\u060c \u0648\u0628\u0641\u0627\u0631\u0642 \u0627\u062d\u0635\u0627\u0626\u064a p=0.027.<\/span><\/p>\n

\u0645\u0642\u0627\u0631\u0646\u0629<\/strong> \u0627\u0644\u0645\u062a\u062b\u0627\u0628\u062a\u0627\u062a<\/strong> \u0627\u0644\u0634\u0639\u0627\u0639\u064a\u0629<\/strong> \u0648\u0627\u0644\u0643\u064a\u0645\u064a\u0627\u0626\u064a\u0629<\/strong> \u0627\u0644\u062d\u064a\u0648\u064a\u0629<\/strong> \u0648\u0627\u0644\u0647\u0631\u0645\u0648\u0646\u064a\u0629<\/strong> \u0627\u0644\u0628\u062f\u0626\u064a\u0651\u0629<\/strong> \u0628\u064a\u0646 \u0630\u0631\u0627\u0639\u064a \u0627\u0644\u062f\u0651\u0631\u0627\u0633\u0629<\/strong><\/span><\/p>\n

\u0644\u0645 \u062a\u0628\u062f\u0650 \u0627\u0644\u0645\u0631\u064a\u0636\u0627\u062a \u0641\u064a \u0630\u0631\u0627\u0639\u064a \u0627\u0644\u062f\u0651\u0631\u0627\u0633\u0629 \u0623\u064a\u0651\u0629 \u0641\u0631\u0648\u0642\u0627\u062a \u0630\u0627\u062a \u062f\u0644\u0627\u0644\u0629 \u0625\u062d\u0635\u0627\u0626\u064a\u0629 \u0644\u062f\u0649 \u0639\u0642\u062f \u0627\u0644\u0645\u0642\u0627\u0631\u0646\u0629 \u0628\u064a\u0646 \u0645\u0631\u064a\u0636\u0627\u062a \u0627\u0644\u062e\u0637\u064a\u0646 \u0627\u0644\u0639\u0644\u0627\u062c\u064a\u064a\u0646 \u0645\u0646 \u062d\u064a\u062b \u0642\u064a\u0645 \u062c\u0645\u064a\u0639 \u0627\u0644\u0645\u062a\u062b\u0627\u0628\u062a\u0627\u062a \u0627\u0644\u0634\u0639\u0627\u0639\u064a\u0629 \u0648\u0627\u0644\u0643\u064a\u0645\u064a\u0627\u0626\u064a\u0629 \u0627\u0644\u062d\u064a\u0648\u064a\u0629 \u0648\u0627\u0644\u0647\u0631\u0645\u0648\u0646\u064a\u0629 \u0627\u0644\u0628\u062f\u0626\u064a\u0651\u0629 (<\/strong>P<\/em><\/strong>>>0.05<\/strong>)<\/strong>. \u0648\u0643\u0630\u0644\u0643 \u0644\u0645 \u062a\u0638\u0647\u0631 \u0623\u064a\u0651\u0629 \u0641\u0648\u0627\u0631\u0642 \u0630\u0627\u062a \u062f\u0644\u0627\u0644\u0629 \u0627\u062d\u0635\u0627\u0626\u064a\u0629 \u0645\u0646 \u062d\u064a\u062b \u062d\u0627\u0644\u0629 \u0641\u064a\u062a\u0627\u0645\u064a\u0646 D \u0648\u0641\u0642\u0627\u064b \u0644\u062a\u0635\u0646\u064a\u0641 IOM<\/strong> (81.<\/strong>P<\/em><\/strong>=0<\/strong>)<\/strong>\u060c<\/strong> \u0623\u0648 \u0627\u0644\u062a\u0651\u0635\u0646\u064a\u0641 \u0627\u0644\u0645\u0628\u0646\u064a \u0639\u0644\u0649 \u0627\u0644\u062a\u0631\u0627\u0643\u064a\u0632 \u0627\u0644\u0645\u0648\u0635\u0649 \u0628\u0647\u0627 \u0644\u0647\u0630\u0647 \u0627\u0644\u062c\u0645\u0647\u0631\u0629 \u0639\u0627\u0644\u064a\u0629 \u0627\u0644\u062e\u0637\u0648\u0631\u0629 \u0645\u0646 \u0627\u0644\u0645\u0631\u064a\u0636\u0627\u062a (P<\/em><\/strong>=0.93<\/strong>) (\u0627\u0644\u062c\u062f\u0648\u0644 2<\/strong>). <\/strong>\u00a0<\/span><\/p>\n

\u0627\u0644\u0639\u0644\u0627\u0642\u0629 \u0628\u064a\u0646 \u0645\u0646\u0633\u0628 \u0643\u062a\u0644\u0629 \u0627\u0644\u062c\u0633\u0645 <\/strong>BMI<\/strong> \u0648\u062a\u0631\u0627\u0643\u064a\u0632<\/strong>25(OH)D <\/strong><\/span><\/p>\n

\u0643\u0627\u0646 \u0627\u0644\u0645\u062a\u0648\u0633\u0637 \u0627\u0644\u062d\u0633\u0627\u0628\u064a \u0644\u062a\u0631\u0627\u0643\u064a\u0632 25(OH)D \u0627\u0644\u0628\u062f\u0626\u064a\u0651\u0629 \u0644\u062f\u0649 \u0634\u0631\u064a\u062d\u0629 \u0627\u0644\u0645\u0631\u064a\u0636\u0627\u062a \u0627\u0644\u0628\u062f\u064a\u0646\u0627\u062a (BMI \u226530 \u0643\u063a\/\u06452<\/sup>) \u0623\u062e\u0641\u0636 [9.65 \u00b15.66] (\u0646\u063a\/\u0645\u0644) \u0648\u0628\u0641\u0627\u0631\u0642\u064d \u0630\u064a \u062f\u0644\u0627\u0644\u0629\u064d \u0625\u062d\u0635\u0627\u0626\u064a\u0651\u0629 (0.048=P<\/em>) \u0645\u0642\u0627\u0631\u0646\u0629\u064b \u0628\u0645\u062a\u0648\u0633\u0637 \u0627\u0644\u062a\u0651\u0631\u0627\u0643\u064a\u0632 [14.07 \u00b17.7] (\u0646\u063a\/\u0645\u0644) \u0644\u062f\u0649 \u0627\u0644\u0645\u0631\u064a\u0636\u0627\u062a \u0637\u0628\u064a\u0639\u064a\u0651\u0627\u062a \u0645\u0646\u0633\u0628 \u0643\u062a\u0644\u0629 \u0627\u0644\u062c\u0633\u0645 \u0623\u0648 \u0632\u0627\u0626\u062f\u0627\u062a \u0627\u0644\u0648\u0632\u0646 (\u0623\u064a <\/strong>\u0627\u0644\u0644\u0648\u0627\u062a\u064a \u0643\u0627\u0646\u062a \u0642\u064a\u0645 BMI \u0644\u062f\u064a\u0647\u0646\u0651 <30 \u0643\u063a\/\u06452<\/sup>).<\/span><\/p>\n

\u062a\u0623\u062b\u064a\u0631<\/strong> \u062c\u0631\u0639\u062a\u064a \u0641\u064a\u062a\u0627\u0645\u064a\u0646<\/strong> D3<\/sub><\/strong> (<\/strong>D800<\/sub> \u0628\u0627\u0644\u0645\u0642\u0627\u0631\u0646\u0629 \u0645\u0639 <\/strong>D5800<\/sub>) \u0639\u0644\u0649<\/strong> \u062a\u0631\u0627\u0643\u064a\u0632<\/strong> 25(OH)D<\/strong> \u0641\u064a \u062e\u062a\u0627\u0645 \u0627\u0644\u0634\u0651\u0648\u0637 \u0627\u0644\u0639\u0644\u0627\u062c\u064a<\/strong><\/span><\/p>\n

\u0623\u0628\u062f\u062a \u062c\u0645\u064a\u0639 \u0627\u0644\u0645\u0631\u064a\u0636\u0627\u062a \u0641\u064a \u0643\u0644\u062a\u0627 \u0630\u0631\u0627\u0639\u064a \u0627\u0644\u062f\u0651\u0631\u0627\u0633\u0629 \u0632\u064a\u0627\u062f\u0629\u064b \u0641\u064a \u0642\u064a\u0645 \u062a\u0631\u0627\u0643\u064a\u063225(OH)D \u0627\u0633\u062a\u062c\u0627\u0628\u0629\u064b \u0644\u0644\u0628\u0631\u0646\u0627\u0645\u062c \u0627\u0644\u0639\u0644\u0627\u062c\u064a \u0645\u0639 \u0623\u0641\u0636\u0644\u064a\u0651\u0629 \u0644\u0644\u062e\u0637\u0651 \u0627\u0644\u0639\u0644\u0627\u062c\u064a \u0628\u0627\u0644\u062c\u0631\u0639\u0629 \u0627\u0644\u0623\u0639\u0644\u0649 \u0645\u0646 \u0641\u064a\u062a\u0627\u0645\u064a\u0646 D3<\/sub>\u060c \u062d\u064a\u062b \u0627\u0632\u062f\u0627\u062f\u062a \u0642\u064a\u0645 \u062a\u0631\u0627\u0643\u064a\u0632 25(OH)D \u0641\u064a \u062e\u062a\u0627\u0645 \u0627\u0644\u0634\u0648\u0637 \u0627\u0644\u0639\u0644\u0627\u062c\u064a \u0628\u0645\u0642\u062f\u0627\u0631 [15.04 \u00b110.3] \u0644\u062f\u0649 \u0645\u0631\u064a\u0636\u0627\u062a \u0627\u0644\u062e\u0637 \u0627\u0644\u0639\u0644\u0627\u062c\u064a (D800<\/sub>)\u060c \u0645\u0642\u0627\u0628\u0644 \u0632\u064a\u0627\u062f\u0629 \u0623\u0643\u0628\u0631 (x1.5) \u0648\u0642\u062f\u0631\u0647\u0627 [22.46 \u00b112.88] \u0641\u064a \u0645\u0631\u064a\u0636\u0627\u062a \u0627\u0644\u062e\u0637\u0651 \u0627\u0644\u0639\u0644\u0627\u062c\u064a (D5800<\/sub>)\u060c \u0648\u0643\u0627\u0646 \u0627\u0644\u0641\u0627\u0631\u0642 \u0628\u064a\u0646 \u0627\u0644\u0645\u062a\u0648\u0633\u0637\u064a\u0646 \u0627\u0644\u062d\u0633\u0627\u0628\u064a\u064a\u0646 \u0644\u0642\u064a\u0645 \u0627\u0644\u0632\u064a\u0627\u062f\u0627\u062a \u0641\u064a \u0627\u0644\u062e\u0637\u0651\u064a\u0646 \u0627\u0644\u0639\u0644\u0627\u062c\u064a\u064a\u0646 \u0630\u0627 \u062f\u0644\u0627\u0644\u0629\u064d \u0625\u062d\u0635\u0627\u0626\u064a\u0651\u0629 (P=0.034)\u060c \u0643\u0645\u0627 \u064a\u0648\u0636\u0651\u062d \u0627\u0644\u062c\u062f\u0648\u0644 (3).<\/strong><\/span><\/p>\n

\"\"<\/span><\/p>\n

\"\"<\/span><\/p>\n

\u062a\u0623\u062b\u064a\u0631<\/strong> \u0645\u062f\u0629<\/strong> \u0627\u0644\u0627\u0644\u062a\u0632\u0627\u0645<\/strong> \u0628\u0627\u0644\u062e\u0637<\/strong> \u0627\u0644\u0639\u0644\u0627\u062c\u064a<\/strong> \u0639\u0644\u0649<\/strong> \u062a\u0631\u0627\u0643\u064a\u0632<\/strong> 25(OH)D<\/strong> \u0641\u064a \u062e\u062a\u0627\u0645 \u0627\u0644\u0634\u0651\u0648\u0637 \u0627\u0644\u0639\u0644\u0627\u062c\u064a<\/strong><\/span><\/p>\n

\u062a\u0646\u0627\u0633\u0628\u062a \u0627\u0644\u0632\u0651\u064a\u0627\u062f\u0629 \u0627\u0644\u0645\u062d\u0642\u0651\u0642\u0629 \u0641\u064a \u062a\u0631\u0627\u0643\u064a\u0632 25(OH)D \u0628\u0645\u062f\u0629 \u0627\u0644\u0627\u0644\u062a\u0632\u0627\u0645 \u0628\u0627\u0644\u062e\u0637 \u0627\u0644\u0639\u0644\u0627\u062c\u064a \u0627\u0644\u0623\u0648\u0644 \u0641\u062d\u0633\u0628\u060c \u062d\u064a\u062b \u0628\u0644\u063a\u062a \u0627\u0644\u0632\u064a\u0627\u062f\u0629 \u0641\u064a \u062a\u0631\u0627\u0643\u064a\u0632 25(OH)D [8.41 \u00b16.7] \u0641\u064a \u0627\u0644\u0645\u062c\u0645\u0648\u0639\u0629 \u0627\u0644\u0641\u0631\u0639\u064a\u0651\u0629 \u0627\u0644\u062a\u064a \u0627\u0644\u062a\u0632\u0645\u062a \u0645\u0631\u064a\u0636\u0627\u062a\u0647\u0627 \u0628\u0627\u0644\u062e\u0637 \u0627\u0644\u0639\u0644\u0627\u062c\u064a\u0651 \u0627\u0644\u0645\u062a\u0636\u0645\u0651\u0646 \u0627\u0644\u062c\u0631\u0639\u0629 \u0627\u0644\u062f\u0651\u0646\u064a\u0627 \u0645\u0646 VitD3<\/sub> \u0645\u062f\u0651\u0629 \u062a\u0642\u0644 \u0639\u0646 \u0633\u062a\u0651\u0629 \u0623\u0634\u0647\u0631 (6\u2265D800)\u060c <\/strong>\u0641\u064a \u062d\u064a\u0646 \u0648\u0635\u0644\u062a \u0647\u0630\u0647 \u0627\u0644\u0632\u064a\u0627\u062f\u0629 \u0625\u0644\u0649 [20.15\u00b19.75] \u0646\u063a\/\u0645\u0644 \u0641\u064a \u0627\u0644\u0645\u062c\u0645\u0648\u0639\u0629 \u0627\u0644\u062a\u064a \u0627\u0644\u062a\u0632\u0645\u062a \u0645\u0631\u064a\u0636\u0627\u062a\u0647\u0627 \u0628\u0627\u0644\u062c\u0631\u0639\u0629 \u0630\u0627\u062a\u0647\u0627 \u0644\u0643\u0646 \u0644\u0645\u062f\u0651\u0629\u064d \u0641\u0627\u0642\u062a \u0627\u0644\u0633\u062a\u0651\u0629 \u0623\u0634\u0647\u0631 (6<D800)\u060c \u0648\u0643\u0627\u0646 \u0627\u0644\u0641\u0627\u0631\u0642 \u0628\u064a\u0646 \u0627\u0644\u0645\u062c\u0645\u0648\u0639\u062a\u064a\u0646 \u0630\u0627 \u062f\u0644\u0627\u0644\u0629\u064d \u0625\u062d\u0635\u0627\u0626\u064a\u0651\u0629 (P<\/em><\/strong>1,2<\/sub><\/strong>=<\/strong>0.017<\/strong>). \u0648\u0628\u0627\u0644\u0645\u0642\u0627\u0628\u0644 \u062a\u0642\u0627\u0631\u0628\u062a \u0627\u0644\u0632\u064a\u0627\u062f\u0629 \u0627\u0644\u0645\u062a\u062d\u0642\u0651\u0642\u0629 \u0641\u064a \u0642\u064a\u0645 \u062a\u0631\u0627\u0643\u064a\u0632 25(OH)D \u0628\u064a\u0646 \u0627\u0644\u0645\u062c\u0645\u0648\u0639\u062a\u064a\u0646 \u0627\u0644\u0641\u0631\u0639\u064a\u062a\u064a\u0646 \u0644\u0644\u062e\u0637 \u0627\u0644\u0639\u0644\u0627\u062c\u064a \u0627\u0644\u062b\u0627\u0646\u064a \u0627\u0644\u0630\u064a \u0627\u0634\u062a\u0645\u0644\u062c\u0631\u0639\u0629 \u0623\u0639\u0644\u0649 \u0645\u0646 VitD3<\/sub> (D5800<\/sub><\/strong>)\u061b \u062d\u064a\u062b \u0643\u0627\u0646\u062a \u0627\u0644\u0632\u064a\u0627\u062f\u0629 [22.19 \u00b114.6] \u0641\u064a \u0645\u062c\u0645\u0648\u0639\u0629 (6\u2265D5800<\/sub>) \u0648\u0628\u0644\u063a\u062a [22.86 \u00b110.6] \u0641\u064a \u0645\u062c\u0645\u0648\u0639\u0629 (<\/strong>6<\/strong><<\/strong>D5800<\/sub><\/strong>)<\/strong>\u060c \u0648\u062f\u0639\u0645\u062a \u0642\u064a\u0645\u0629 p<\/em> (P<\/em>3,4<\/sub>=0.89) \u0639\u062f\u0645 \u0648\u062c\u0648\u062f \u0641\u0627\u0631\u0642\u064d \u0630\u064a \u062f\u0644\u0627\u0644\u0629\u064d \u0625\u062d\u0635\u0627\u0626\u064a\u0651\u0629 \u0628\u064a\u0646 \u0645\u062c\u0645\u0648\u0639\u062a\u064a \u0627\u0644\u062e\u0637 \u0627\u0644\u0639\u0644\u0627\u062c\u064a \u0627\u0644\u062b\u0627\u0646\u064a (<\/strong>6<\/strong>\u2265<\/strong>D5800<\/sub><\/strong>)<\/strong> \u0648 (<\/strong>6<\/strong><<\/strong>D5800<\/sub><\/strong>)<\/strong>. <\/span>\u062d\u0642\u0651\u0642\u062a \u0645\u0631\u064a\u0636\u0627\u062a \u0627\u0644\u0645\u062c\u0645\u0648\u0639\u0629 \u0627\u0644\u0641\u0631\u0639\u064a\u0651\u0629 \u0644\u0644\u062e\u0637\u0651 \u0627\u0644\u0639\u0644\u0627\u062c\u064a\u0651 \u0639\u0627\u0644\u064a \u0627\u0644\u062c\u0631\u0639\u0629 \u0645\u0646 VitD3<\/sub> (6<\/strong><<\/strong>D5800<\/sub><\/strong>) \u0632\u064a\u0627\u062f\u0629\u064b \u0641\u064a \u062a\u0631\u0627\u0643\u064a\u0632 25(OH)D \u062a\u0641\u0648\u0642 \u0645\u0631\u064a\u0636\u0627\u062a \u0627\u0644\u0645\u062c\u0645\u0648\u0639\u0629 \u0627\u0644\u0641\u0631\u0639\u064a\u0651\u0629 \u0644\u0644\u062e\u0637\u0651 \u0627\u0644\u0639\u0644\u0627\u062c\u064a \u0627\u0644\u0623\u0648\u0644 \u0645\u0646\u062e\u0641\u0636 \u0627\u0644\u062c\u0631\u0639\u0629 (6<\/strong><<\/strong>D800<\/sub><\/strong>)\u060c \u0648\u0628\u0641\u0627\u0631\u0642 \u0630\u064a \u062f\u0644\u0627\u0644\u0629\u064d \u0625\u062d\u0635\u0627\u0626\u064a\u0651\u0629 (P<\/em>2<\/sub>,4= <\/sub>0.003). \u0643\u0645\u0627 \u0641\u0627\u0642 \u0627\u0644\u0625\u0631\u062a\u0641\u0627\u0639 \u0627\u0644\u0645\u062d\u0642\u0651\u0642 \u0641\u064a \u062a\u0631\u0627\u0643\u064a\u0632 25(OH)D \u0641\u064a \u0643\u0644\u062a\u0627 \u0645\u062c\u0645\u0648\u0639\u062a\u064a \u0627\u0644\u062e\u0637 \u0627\u0644\u0639\u0644\u0627\u062c\u064a \u0627\u0644\u062b\u0627\u0646\u064a (6\u2265D5800<\/sub>) \u0648(6<D5800<\/sub>) \u0627\u0644\u0632\u064a\u0627\u062f\u0629 \u0627\u0644\u062d\u0627\u0635\u0644\u0629 \u0641\u064a \u0627\u0644\u0645\u062c\u0645\u0648\u0639\u0629 \u0627\u0644\u0641\u0631\u0639\u064a\u0629 (6\u2265(D800<\/sub> \u0628\u0645\u0642\u062f\u0627\u0631 x2.5\u060c \u0648\u0628\u0641\u0627\u0631\u0642 \u0630\u064a \u062f\u0644\u0627\u0644\u0629\u064d \u0625\u062d\u0635\u0627\u0626\u064a\u0651\u0629 (P<\/em>1<\/sub>,3<\/sub>= 0.004 \u060c<\/sub>P1,<\/sub>4<\/sub>= 0.006 )\u060c \u0643\u0645\u0627 \u0647\u0648 \u0645\u0648\u0636\u062d \u0641\u064a \u0627\u0644\u0645\u062e\u0637\u0637 \u0627\u0644\u0628\u064a\u0627\u0646\u064a\u06511 .<\/span><\/p>\n

\u0645\u0642\u0627\u0631\u0646\u0629<\/strong> \u0627\u0644\u0645\u062a\u0648\u0633\u0637\u0627\u062a<\/strong> \u0627\u0644\u062d\u0633\u0627\u0628\u064a\u0629<\/strong> \u0644\u0641\u0648\u0627\u0631\u0642<\/strong> \u0642\u064a\u0627\u0633\u0627\u062a<\/strong> \u0627\u0644\u0643\u062b\u0627\u0641\u0629<\/strong> \u0627\u0644\u0645\u0639\u062f\u0646\u064a\u0651\u0629<\/strong> \u0627\u0644\u0639\u0638\u0645\u064a\u0629 <\/strong>BMD<\/strong>\u060c T-Score<\/strong>\u060c <\/strong>z<\/strong>-Score<\/strong> \u0641\u064a <\/strong>\u0627\u0644\u0641\u0642\u0631\u0627\u062a <\/strong><\/span>\u0627\u0644\u0642\u0637\u0646\u064a\u0629<\/strong><\/span><\/p>\n

\u0628\u064a\u0651\u0646\u062a \u0646\u062a\u0627\u0626\u062c \u0647\u0630\u0647 \u0627\u0644\u062f\u0651\u0631\u0627\u0633\u0629 \u062a\u062d\u0633\u0646\u0627\u064b \u0645\u0644\u062d\u0648\u0638\u0627\u064b \u0641\u064a \u0642\u064a\u0645 \u0627\u0644\u0645\u062a\u0648\u0633\u0637\u0627\u062a \u0627\u0644\u062d\u0633\u0627\u0628\u064a\u0629 \u0644\u0641\u0648\u0627\u0631\u0642 \u0642\u064a\u0627\u0633\u0627\u062a \u0627\u0644\u0643\u062b\u0627\u0641\u0629 \u0627\u0644\u0645\u0639\u062f\u0646\u064a\u0651\u0629 \u0627\u0644\u0639\u0638\u0645\u064a\u0629 BMD \u0648(T-Score) \u0648(z-Score) \u0644\u0644\u0641\u0642\u0631\u0627\u062a \u0627\u0644\u0642\u0637\u0646\u064a\u0629 \u0644\u062f\u0649 \u0627\u0644\u0645\u0631\u064a\u0636\u0627\u062a \u0641\u064a \u0643\u0644\u0627 \u0627\u0644\u062e\u0637\u064a\u0646 \u0627\u0644\u0639\u0644\u0627\u062c\u064a\u064a\u0646\u060c \u0643\u0645\u0627 \u0647\u0648 \u0645\u0648\u0636\u062d \u0641\u064a \u0627\u0644\u062c\u062f\u0648\u0644 3. \u00a0\u0648\u0628\u0627\u0644\u0645\u0642\u0627\u0631\u0646\u0629\u060c\u00a0 \u062a\u062a\u0636\u062d \u0623\u0641\u0636\u0644\u064a\u0629 \u0627\u0644\u062e\u0637 \u0627\u0644\u0639\u0644\u0627\u062c\u064a (D5800<\/sub>) \u0645\u0646 \u062d\u064a\u062b \u0627\u0644\u0632\u064a\u0627\u062f\u0629 \u0627\u0644\u062d\u0627\u0635\u0644\u0629 \u0644\u062f\u0649 \u0645\u0631\u064a\u0636\u0627\u062a\u0647 \u0641\u064a \u0641\u0648\u0627\u0631\u0642 \u0642\u064a\u0645 \u0643\u0644\u0651\u064d \u0645\u0646 \u0627\u0644\u0640 BMD \u0648 T-Score \u0648\u0627\u0644\u062a\u064a \u0642\u0627\u0631\u0628\u062a \u062b\u0644\u0627\u062b\u0629 \u0623\u0636\u0639\u0627\u0641 \u0627\u0644\u0632\u064a\u0627\u062f\u0629 \u0627\u0644\u062d\u0627\u0635\u0644\u0629 \u0641\u064a \u0627\u0644\u062e\u0637 \u0627\u0644\u0639\u0644\u0627\u062c\u064a (D800<\/sub>)\u060c \u0648\u0628\u0641\u0627\u0631\u0642 \u0630\u064a \u062f\u0644\u0627\u0644\u0629\u064d \u0625\u062d\u0635\u0627\u0626\u064a\u0651\u0629 (p<\/em>=0.002). \u0643\u0645\u0627 \u0628\u0631\u0647\u0646 \u0627\u0644\u062a\u0651\u062d\u0633\u0651\u0646 \u0627\u0644\u0645\u0644\u062d\u0648\u0638 \u0641\u064a \u0642\u064a\u0645 (z-Score) \u0641\u0639\u0651\u0627\u0644\u064a\u0629 \u0643\u0644\u0627 \u0627\u0644\u062e\u0637\u064a\u0646 \u0627\u0644\u0639\u0644\u0627\u062c\u064a\u064a\u0646 \u0641\u064a \u062a\u062d\u0642\u064a\u0642 \u0627\u0644\u0645\u062d\u0635\u0644\u0627\u062a \u0627\u0644\u0639\u0644\u0627\u062c\u064a\u0651\u0629\u060c \u0645\u0639 \u0623\u0641\u0636\u0644\u064a\u0651\u0629\u064d \u0644\u0644\u062e\u0637 \u0627\u0644\u0639\u0644\u0627\u062c\u064a (D5800<\/sub>) \u0627\u0644\u0630\u064a \u0641\u0627\u0642\u062a \u0627\u0644\u0632\u064a\u0627\u062f\u0629 \u0627\u0644\u0645\u062a\u062d\u0642\u0651\u0642\u0629 \u0644\u062f\u0649 \u0645\u0631\u064a\u0636\u0627\u062a\u0647 \u0636\u0639\u0641\u064a \u0627\u0644\u0632\u064a\u0627\u062f\u0629 \u0641\u064a \u0645\u0631\u064a\u0636\u0627\u062a \u0627\u0644\u062e\u0637 \u0627\u0644\u0639\u0644\u0627\u062c\u064a (D800<\/sub>)\u060c \u0648\u0628\u0641\u0627\u0631\u0642 \u0627\u062d\u0635\u0627\u0626\u064a (p<\/em>=0.015) (\u0627\u0644\u062c\u062f\u0648\u0644 3). \u0648\u062a\u0646\u0627\u0633\u0628 \u0627\u0644\u062a\u0651\u062d\u0633\u0646 \u0641\u064a \u0642\u064a\u0645 \u0643\u0644\u0651\u064d \u0645\u0646 BMD \u0648T-Score \u0648Z-Score \u0645\u0639 \u0645\u062f\u0651\u0629 \u0627\u0644\u062a\u0632\u0627\u0645 \u0627\u0644\u0645\u0631\u064a\u0636\u0627\u062a \u0628\u0627\u0644\u062e\u0637\u0651 \u0627\u0644\u0639\u0644\u0627\u062c\u064a \u0633\u0648\u0627\u0621 \u0645\u0646\u062e\u0641\u0636 \u062c\u0631\u0639\u0629 \u0641\u064a\u062a\u0627\u0645\u064a\u0646 D3<\/sub> (D800<\/sub>) \u0623\u0645 \u0645\u0631\u062a\u0641\u0639 \u0627\u0644\u062c\u0631\u0639\u0629 \u0645\u0646\u0647 (D5800<\/sub>)\u060c \u0643\u0645\u0627 \u0647\u0648 \u0645\u0628\u064a\u0651\u0646 \u0641\u064a \u0627\u0644\u062c\u062f\u0648\u0644 4\u060c \u063a\u064a\u0631 \u0623\u0646\u0651 \u0647\u0630\u0627 \u0627\u0644\u062a\u0651\u062d\u0633\u0651\u0646 \u0627\u0644\u0645\u0631\u062a\u0628\u0637 \u0628\u0645\u062f\u0651\u0629 \u062a\u0646\u0627\u0648\u0644 \u0641\u064a\u062a\u0627\u0645\u064a\u0646 D3<\/sub> \u0643\u0627\u0646 \u0630\u0627 \u062f\u0644\u0627\u0644\u0629\u064d \u0625\u062d\u0635\u0627\u0626\u064a\u0651\u0629 \u0641\u064a \u0645\u0631\u064a\u0636\u0627\u062a \u0627\u0644\u062e\u0637 \u0627\u0644\u0639\u0644\u0627\u062c\u064a \u0627\u0644\u062b\u0627\u0646\u064a \u0641\u062d\u0633\u0628 (P=<\/strong>0.039<\/strong>).<\/span><\/p>\n

\"\u0627\u0644\u0634\u0643\u0644
\u0627\u0644\u0634\u0643\u0644 (1): \u062a\u0623\u062b\u064a\u0631 \u0645\u062f\u0629 \u0627\u0644\u0627\u0644\u062a\u0632\u0627\u0645 \u0628\u0627\u0644\u062e\u0637 \u0627\u0644\u0639\u0644\u0627\u062c\u064a (D800 \u0645\u0642\u0627\u0628\u0644 D5800) \u0641\u064a \u062a\u0631\u0627\u0643\u064a\u0632 25 (OH)D \u0641\u064a \u062e\u062a\u0627\u0645 \u0627\u0644\u0634\u0648\u0637 \u0627\u0644\u0639\u0644\u0627\u062c\u064a<\/span><\/strong><\/figcaption><\/figure>\n

\u0648\u0644\u062f\u0649 \u0639\u0642\u062f \u0645\u0642\u0627\u0631\u0646\u0627\u062a \u0644\u0641\u0631\u0648\u0642\u0627\u062a \u0642\u064a\u0645 \u0627\u0644\u0640 T-Score \u0628\u064a\u0646 \u0627\u0644\u0645\u062c\u0645\u0648\u0639\u0627\u062a \u0627\u0644\u0641\u0631\u0639\u064a\u0629 \u0644\u062e\u0637\u064a \u0627\u0644\u0639\u0644\u0627\u062c\u060c \u0641\u0627\u0642\u062a \u0627\u0644\u0632\u064a\u0627\u062f\u0629 \u0627\u0644\u062a\u064a \u062a\u062d\u0642\u0651\u0642\u062a \u0644\u062f\u0649 \u0645\u0631\u064a\u0636\u0627\u062a \u0627\u0644\u0645\u062c\u0645\u0648\u0639\u0629 \u0627\u0644\u0641\u0631\u0639\u064a\u0629 (6\u2265D5800<\/sub>) 4.5 \u0636\u0639\u0641\u0627\u064b \u0627\u0644\u0632\u064a\u0627\u062f\u0629 \u0644\u062f\u0649 \u0645\u0631\u064a\u0636\u0627\u062a \u0627\u0644\u0645\u062c\u0645\u0648\u0639\u0629 \u0627\u0644\u0641\u0631\u0639\u064a\u0629 (6\u2265D800<\/sub>)\u060c<\/strong> \u0648\u0628\u0641\u0627\u0631\u0642\u064d \u0630\u064a \u062f\u0644\u0627\u0644\u0629 \u0625\u062d\u0635\u0627\u0626\u064a\u0629 P1,<\/sub><\/strong>3<\/sub><\/strong>=0.04)<\/strong>)<\/strong>. \u0643\u0645\u0627 \u0641\u0627\u0642\u062a \u0627\u0644\u0632\u064a\u0627\u062f\u0629 \u0644\u062f\u0649 \u0645\u0631\u064a\u0636\u0627\u062a \u0627\u0644\u0645\u062c\u0645\u0648\u0639\u0629 \u0627\u0644\u0641\u0631\u0639\u064a\u0629 (<\/strong>6<\/strong><<\/strong>D5800<\/sub><\/strong>)<\/strong> \u0628\u0640\u062b\u0645\u0627\u0646\u064a\u0629 \u0623\u0636\u0639\u0627\u0641 \u0627\u0644\u0632\u064a\u0627\u062f\u0629 \u0641\u064a \u0627\u0644\u0645\u062c\u0645\u0648\u0639\u0629 \u0627\u0644\u0641\u0631\u0639\u064a\u0629 (<\/strong>6<\/strong>\u2265<\/strong>D800<\/sub><\/strong>)<\/strong>\u060c \u0648\u0628\u0641\u0627\u0631\u0642\u064d \u0630\u064a \u062f\u0644\u0627\u0644\u0629 \u0625\u062d\u0635\u0627\u0626\u064a\u0651\u0629P<\/em><\/strong><<\/strong>0.001) <\/strong>). \u0643\u0630\u0644\u0643 \u062d\u0642\u0651\u0642\u062a \u0645\u0631\u064a\u0636\u0627\u062a \u0627\u0644\u0645\u062c\u0645\u0648\u0639\u0629 \u0627\u0644\u0641\u0631\u0639\u064a\u0629 (<\/strong>6<\/strong><<\/strong>D5800<\/sub><\/strong>)<\/strong> \u062a\u062d\u0633\u0651\u0646\u0627\u064b \u0641\u0627\u0642 \u0627\u0644\u0645\u062c\u0645\u0648\u0639\u0629 \u0627\u0644\u0641\u0631\u0639\u064a\u0629 (<\/strong>6<\/strong><<\/strong>D800<\/sub><\/strong>)<\/strong> \u0628\u0640 \u062b\u0644\u0627\u062b\u0629 \u0623\u0636\u0639\u0627\u0641 (<\/strong>p<\/em><\/strong>=<\/strong>0.004<\/strong>). <\/strong><\/span>\u0643\u0645\u0627 \u062c\u0627\u0621\u062a \u0646\u062a\u0627\u0626\u062c \u0627\u0644\u062a\u062d\u0633\u0651\u0646 \u0641\u064a \u0642\u064a\u0645 \u0627\u0644\u0640 Z-Score \u0644\u062a\u0624\u0643\u0651\u062f \u0623\u0641\u0636\u0644\u064a\u0651\u0629\u064b \u0645\u062f\u0639\u0648\u0645\u0629\u064b \u0628\u0641\u0648\u0627\u0631\u0642 \u0630\u0627\u062a \u062f\u0644\u0627\u0644\u0627\u062a \u0625\u062d\u0635\u0627\u0626\u064a\u0651\u0629 \u0644\u0644\u062e\u0637 \u0627\u0644\u0639\u0644\u0627\u062c\u064a \u0627\u0644\u062b\u0627\u0646\u064a (D5800<\/sub>) \u0641\u064a \u0645\u062c\u0645\u0648\u0639\u062a\u064a\u0647 \u0627\u0644\u0641\u0631\u0639\u064a\u062a\u064a\u0646 \u0627\u0644\u0645\u0639\u0631\u0651\u0641\u062a\u064a\u0646 \u0628\u0646\u0627\u0621\u064b \u0639\u0644\u0649 \u0645\u062f\u0651\u0629 \u0627\u0644\u0627\u0644\u062a\u0632\u0627\u0645 \u0648\u0630\u0644\u0643 \u0628\u0627\u0644\u0645\u0642\u0627\u0631\u0646\u0629 \u0645\u0639 \u0627\u0644\u062e\u0637\u0651 \u0627\u0644\u0639\u0644\u0627\u062c\u064a \u0627\u0644\u0623\u0648\u0651\u0644. \u0643\u0645\u0627 \u062d\u0633\u0651\u0646\u062a \u0645\u062f\u0629 \u0627\u0644\u062a\u0632\u0627\u0645\u064d \u0623\u0637\u0648\u0644 (6< \u0623\u0634\u0647\u0631) \u0645\u0646 \u0627\u0644\u0632\u064a\u0627\u062f\u0629 \u0641\u064a \u0642\u064a\u0645 \u0627\u0644\u0640 Z-Score\u00a0 \u0644\u062f\u0649 \u0645\u0631\u064a\u0636\u0627\u062a \u0627\u0644\u062e\u0637 \u0627\u0644\u0639\u0644\u0627\u062c\u064a \u0627\u0644\u0623\u0648\u0644.\u00a0<\/span><\/p>\n

\u0645\u0642\u0627\u0631\u0646\u0629<\/strong> \u0641\u0639\u0651\u0627\u0644\u064a\u0629 \u0627\u0644\u062e\u0637\u064a\u0646 \u0627\u0644\u0639\u0644\u0627\u062c\u064a\u064a\u0646 \u0641\u064a \u062a\u062d\u0642\u064a\u0642 \u0627\u0644\u0643\u0641\u0627\u064a\u0629 \u0645\u0646<\/strong> \u0641\u064a\u062a\u0627\u0645\u064a\u0646<\/strong> D<\/strong> (<\/strong>\u062a\u0631\u0643\u064a\u0632<\/strong> 25(OH)D<\/strong> \u226530 <\/strong>\u0646\u063a\/\u0645\u0644<\/strong>) <\/strong><\/span><\/p>\n

\u0628\u0644\u063a \u0639\u062f\u062f \u0627\u0644\u0645\u0631\u064a\u0636\u0627\u062a \u0627\u0644\u0644\u0648\u0627\u062a\u064a \u062d\u0642\u0642\u0646 \u062a\u0631\u0627\u0643\u064a\u0632 \u0645\u0635\u0644\u064a\u0651\u0629 \u0645\u0646 25(OH)D \u226530 \u0646\u063a\/\u0645\u0644 \u0641\u064a \u0643\u0644\u0627 \u0627\u0644\u062e\u0637\u064a\u0646 \u0627\u0644\u0639\u0644\u0627\u062c\u064a\u064a\u0646 31 \u0645\u0631\u064a\u0636\u0629 \u0628\u0646\u0633\u0628\u0629 \u0642\u062f\u0631\u0647\u0627 64.5%\u060c \u062a\u0648\u0632\u0639\u0646 \u0628\u064a\u0646 \/1223 \u0645\u0631\u064a\u0636\u0629 \u0641\u064a \u0627\u0644\u062e\u0637 \u0627\u0644\u0639\u0644\u0627\u062c\u064a \u0627\u0644\u0623\u0648\u0644 (52.2%)\u060c \u0645\u0642\u0627\u0628\u0644 19\/25 \u0645\u0631\u064a\u0636\u0629 (76%) \u0641\u064a \u0627\u0644\u062e\u0637 \u0627\u0644\u0639\u0644\u0627\u062c\u064a \u0627\u0644\u062b\u0627\u0646\u064a\u060c \u0645\u0639 \u0623\u0641\u0636\u0644\u064a\u0629\u064d \u062c\u0644\u064a\u0651\u0629 \u0644\u0644\u062e\u0637 \u0627\u0644\u0639\u0644\u0627\u062c\u064a \u0627\u0644\u062b\u0627\u0646\u064a \u0648\u0628\u0641\u0627\u0631\u0642 \u0630\u064a \u062f\u0644\u0627\u0644\u0629\u064d \u0625\u062d\u0635\u0627\u0626\u064a\u0651\u0629 (P<\/em>=0.037). <\/span>\u0643\u0627\u0646 \u0644\u0645\u062f\u0629 \u0627\u0644\u0627\u0644\u062a\u0632\u0627\u0645 \u0636\u0645\u0646 \u0643\u0644\u0651 \u062e\u0637\u0651\u064d \u0639\u0644\u0627\u062c\u064a \u062a\u0623\u062b\u064a\u0631 \u0645\u0628\u0627\u0634\u0631 \u0641\u064a \u0646\u0633\u0628\u0629 \u0627\u0644\u0645\u0631\u064a\u0636\u0627\u062a \u0627\u0644\u0644\u0627\u062a\u064a \u062d\u0642\u0642\u0646 \u062d\u062f \u0627\u0644\u0643\u0641\u0627\u064a\u0629 \u0627\u0644\u0645\u0642\u062a\u0631\u062d\u060c \u062d\u064a\u062b \u0627\u0642\u062a\u0635\u0631 \u0627\u0644\u0639\u062f\u062f \u0639\u0644\u0649 \u0645\u0631\u064a\u0636\u062a\u064a\u0646 \u0641\u0642\u0637 10\/2 (20%) \u0641\u064a \u0645\u062c\u0645\u0648\u0639\u0629 (6\u2265D800<\/sub>)\u060c \u0641\u064a \u062d\u064a\u0646 \u0648\u0635\u0644\u062a \u0627\u0644\u0646\u0633\u0628\u0629 \u0625\u0644\u0649 ) 13\/1076.9(% \u0641\u064a \u0627\u0644\u0645\u062c\u0645\u0648\u0639\u0629 \u0627\u0644\u0641\u0631\u0639\u064a\u0629 (6<D800<\/sub>). \u0628\u0627\u0644\u0645\u0642\u0627\u0628\u0644\u060c \u0628\u0644\u063a\u062a \u0646\u0633\u0628\u0629 \u0627\u0644\u0645\u0631\u064a\u0636\u0627\u062a \u0627\u0644\u0644\u0627\u062a\u064a \u062d\u0642\u0642\u0646 \u0627\u0644\u0645\u062d\u0635\u0644\u0629 \u0627\u0644\u0639\u0644\u0627\u062c\u064a\u0651\u0629 \u0627\u0644\u0645\u0631\u062c\u0648\u0651\u0629 66.6% (10\/15) \u0641\u064a \u0627\u0644\u0645\u062c\u0645\u0648\u0639\u0629 \u0627\u0644\u0641\u0631\u0639\u064a\u0629 (6\u2265D5800<\/sub>)\u060c \u0641\u064a \u062d\u064a\u0646 \u0648\u0635\u0644\u062a \u0647\u0630\u0647 \u0627\u0644\u0646\u0633\u0628\u0629 \u0644\u062d\u062f\u0648\u062f 90% (9\/10) \u0641\u064a \u0627\u0644\u0645\u062c\u0645\u0648\u0639\u0629 \u0627\u0644\u0641\u0631\u0639\u064a\u0629 (6<D5800<\/sub>)\u060c \u0648\u0628\u0641\u0627\u0631\u0642 \u0630\u064a \u062f\u0644\u0627\u0644\u0629\u064b \u0625\u062d\u0635\u0627\u0626\u064a\u0651\u0629 (P=0.005) \u0628\u064a\u0646 \u062c\u0645\u064a\u0639 \u0627\u0644\u0645\u062c\u0645\u0648\u0639\u0627\u062a \u0627\u0644\u0641\u0631\u0639\u064a\u0629 \u0627\u0644\u0633\u0627\u0628\u0642\u0629 \u0643\u0645\u0627 \u0647\u0648 \u0645\u0628\u064a\u0651\u0646 \u0628\u0627\u0644\u062c\u062f\u0648\u0644 5.<\/span><\/p>\n

\u062f\u0631\u0627\u0633\u0629 \u0627\u0644\u0639\u0644\u0627\u0642\u0629 \u0628\u064a\u0646 \u0627\u0644\u062a\u062d\u0633\u0646<\/strong> \u0641\u064a \u0642\u064a\u0645<\/strong> \u0627\u0644\u0645\u062a\u0648\u0633\u0637\u0627\u062a<\/strong> \u0627\u0644\u062d\u0633\u0627\u0628\u064a\u0629<\/strong> \u0644\u0641\u0648\u0627\u0631\u0642<\/strong> \u0642\u064a\u0627\u0633\u0627\u062a<\/strong> (<\/strong>T-Score<\/strong>) <\/strong>\u0644\u0644\u0641\u0642\u0631\u0627\u062a<\/strong> \u0627\u0644\u0642\u0637\u0646\u064a\u0629<\/strong> \u0648\u062a\u062d\u0642\u064a\u0642<\/strong> \u0627\u0644\u0645\u062d\u0635\u0644\u0629 \u0627\u0644\u0639\u0644\u0627\u062c\u064a\u0651\u0629 \u0627\u0644\u0645\u0633\u062a\u0647\u062f\u0641\u0629 \u0645\u0646 \u062a\u0631\u0627\u0643\u064a\u0632<\/strong> 25(OH)D<\/strong> (\u226530 <\/strong>\u0646\u063a\/\u0645\u0644<\/strong>) <\/strong><\/span><\/p>\n

\u0628\u064a\u0651\u0646 \u0627\u0644\u062a\u062d\u0644\u064a\u0644 \u0627\u0644\u0627\u062d\u0635\u0627\u0626\u064a \u0644\u0628\u064a\u0627\u0646\u0627\u062a \u0627\u0644\u062f\u0631\u0627\u0633\u0629 \u0645\u0646 \u062d\u064a\u062b \u0627\u0644\u062a\u062d\u0633\u0651\u0646 \u0641\u064a \u0642\u064a\u0645 \u0627\u0644\u0645\u062a\u0648\u0633\u0637\u0627\u062a \u0627\u0644\u062d\u0633\u0627\u0628\u064a\u0629 \u0644\u0641\u0648\u0627\u0631\u0642 \u0642\u064a\u0627\u0633\u0627\u062a (T-Score) \u0644\u0644\u0641\u0642\u0631\u0627\u062a \u0627\u0644\u0642\u0637\u0646\u064a\u0629 \u0623\u0641\u0636\u0644\u064a\u0629 \u0644\u0635\u0627\u0644\u062d \u0627\u0644\u0645\u0631\u064a\u0636\u0627\u062a \u0627\u0644\u0644\u0648\u0627\u062a\u064a \u062d\u0642\u0642\u0646 \u062a\u0631\u0627\u0643\u064a\u0632 25(OH)D \u226530 \u0646\u063a\/\u0645\u0644\u060c \u0648\u0628\u0632\u064a\u0627\u062f\u0629 \u0641\u0627\u0642\u062a \u0627\u0644\u0636\u0639\u0641\u060c \u0645\u0642\u0627\u0631\u0646\u0629 \u0645\u0639 \u0627\u0644\u062a\u062d\u0633\u0651\u0646 \u0627\u0644\u062d\u0627\u0635\u0644 \u0644\u062f\u0649 \u0627\u0644\u0645\u0631\u064a\u0636\u0627\u062a \u0627\u0644\u0644\u0648\u0627\u062a\u064a \u0644\u0645 \u064a\u0628\u0644\u063a\u0646 \u062d\u062f \u0627\u0644\u0643\u0641\u0627\u064a\u0629 \u0627\u0644\u0645\u0642\u062a\u0631\u062d \u0645\u0646 \u0641\u064a\u062a\u0627\u0645\u064a\u0646 D\u060c \u0648\u0628\u0641\u0627\u0631\u0642\u064d \u0630\u064a \u062f\u0644\u0627\u0644\u0629\u064d \u0627\u062d\u0635\u0627\u0626\u064a\u0651\u0629 (p<\/em>=0.033). <\/span>\u0643\u0645\u0627 \u0641\u0627\u0642\u062a \u0627\u0644\u0632\u064a\u0627\u062f\u0629 \u0627\u0644\u062d\u0627\u0635\u0644\u0629 \u0641\u064a \u0642\u064a\u0645 \u0627\u0644\u0640 BMD<\/strong> \u0644\u0644\u0641\u0642\u0631\u0627\u062a \u0627\u0644\u0642\u0637\u0646\u064a\u0629 \u0641\u064a \u0634\u0631\u064a\u062d\u0629 \u0627\u0644\u0645\u0631\u064a\u0636\u0627\u062a \u0627\u0644\u0644\u0648\u0627\u062a\u064a \u0628\u0644\u063a\u0646 \u062d\u062f \u0627\u0644\u0643\u0641\u0627\u064a\u0629 \u0645\u0646 \u0641\u064a\u062a\u0627\u0645\u064a\u0646 D \u0627\u0644\u0636\u0639\u0641\u060c \u0648\u0630\u0644\u0643 \u0645\u0642\u0627\u0631\u0646\u0629 \u0645\u0639 \u0627\u0644\u0632\u064a\u0627\u062f\u0629 \u0627\u0644\u062d\u0627\u0635\u0644\u0629 \u0644\u062f\u0649 \u0627\u0644\u0645\u0631\u064a\u0636\u0627\u062a \u0627\u0644\u0644\u0627\u062a\u064a \u0644\u0645 \u064a\u0628\u0644\u063a\u0646 \u062d\u062f \u0627\u0644\u0643\u0641\u0627\u064a\u0629 \u0627\u0644\u0645\u0642\u062a\u0631\u062d\u060c \u0648\u0628\u0641\u0627\u0631\u0642\u064d \u0630\u064a \u062f\u0644\u0627\u0644\u0629\u064d \u0625\u062d\u0635\u0627\u0626\u064a\u0651\u0629 (0.025=p<\/em>).<\/span><\/p>\n

\u0646\u0633\u0628\u0629 \u062a\u062d\u0642\u064a\u0642 \u0627\u0644\u0645\u0631\u064a\u0636\u0627\u062a \u0644\u062a\u0631\u0643\u064a\u0632 <\/strong>(<\/strong> (OH)D3<\/sub><\/strong>25\u226530) <\/strong>\u0641\u064a \u062e\u062a\u0627\u0645 \u062e\u0637\u064a \u0627\u0644\u0645\u0639\u0627\u0644\u062c\u0629<\/strong><\/span><\/p>\n

\u0628\u0644\u063a \u0639\u062f\u062f \u0627\u0644\u0645\u0631\u064a\u0636\u0627\u062a \u0627\u0644\u0644\u0648\u0627\u062a\u064a \u062d\u0642\u0642\u0646 \u0627\u0644\u062a\u0631\u0643\u064a\u0632 \u0627\u0644\u0645\u0642\u062a\u0631\u062d (<\/strong>(OH)D<\/strong>25\u226530)<\/strong> \u0641\u064a \u062e\u062a\u0627\u0645 \u0627\u0644\u0645\u0639\u0627\u0644\u062c\u0629 \u0628\u0627\u0644\u062e\u0637 \u0627\u0644\u0639\u0644\u0627\u062c\u064a \u0627\u0644\u0623\u0648\u0644 12<\/strong> \u0645\u0631\u064a\u0636\u0629 (52%)<\/strong>\u060c \u0641\u064a \u062d\u064a\u0646 \u0641\u0627\u0642\u062a \u0627\u0644\u0646\u0633\u0628\u0629 75% <\/strong>(19<\/strong> \u0645\u0631\u064a\u0636\u0629) \u0641\u064a \u0627\u0644\u062e\u0637 \u0627\u0644\u0639\u0644\u0627\u062c\u064a \u0627\u0644\u062b\u0627\u0646\u064a\u060c \u0648\u0628\u0641\u0627\u0631\u0642 \u0630\u064a \u062f\u0644\u0627\u0644\u0629\u064d \u0625\u062d\u0635\u0627\u0626\u064a\u0651\u0629 (<\/strong>P<\/em><\/strong>=0.017<\/strong>)<\/strong>.<\/span><\/p>\n

\u0627\u0644\u0645\u0646\u0627\u0642\u0634\u0629<\/strong> Discussion<\/strong><\/span><\/p>\n

\u00a0\u062a\u0634\u0645\u0644 \u0639\u0648\u0627\u0642\u0628 \u0627\u0633\u062a\u062e\u062f\u0627\u0645 \u0645\u062b\u0628\u0637\u0627\u062a \u0627\u0644\u0623\u0631\u0648\u0645\u0627\u062a\u0627\u0632 (<\/strong>AIs<\/strong>)<\/strong> \u062a\u062f\u0647\u0648\u0631\u0627\u064b \u0645\u062a\u0631\u0642\u064a\u0627\u064b \u0641\u064a \u0628\u0646\u064a\u0629 \u0627\u0644\u0639\u0638\u0627\u0645 \u0644\u062f\u0649 \u0645\u0631\u064a\u0636\u0627\u062a \u0633\u0631\u0637\u0627\u0646 \u0627\u0644\u062b\u062f\u064a \u0648\u0632\u064a\u0627\u062f\u0629\u064b \u0641\u064a \u0645\u0639\u062f\u0644\u0627\u062a \u0643\u0633\u0648\u0631 \u0627\u0644\u062a\u062e\u0644\u062e\u0644 \u0627\u0644\u0639\u0638\u0645\u064a\u060c \u0645\u0645\u0627 \u064a\u0624\u062f\u064a \u0625\u0644\u0649 \u062c\u0645\u0644\u0629\u064d \u0645\u0646 \u0627\u0644\u0639\u0642\u0627\u0628\u064a\u0644 \u062a\u0634\u0645\u0644 \u0627\u0644\u0623\u0644\u0645 \u0627\u0644\u0645\u0632\u0645\u0646 \u0648\u062a\u0631\u062f\u064a \u062c\u0648\u062f\u0629 \u0627\u0644\u062d\u064a\u0627\u0629 \u0648\u0632\u064a\u0627\u062f\u0629 \u0627\u062e\u062a\u0637\u0627\u0631 \u0627\u0644\u0648\u0641\u0627\u0629. 5-10 <\/sup><\/span>\u00a0\u0646\u0635\u0651\u062a \u0627\u0644\u062f\u0644\u0627\u0626\u0644 \u0627\u0644\u0625\u0631\u0634\u0627\u062f\u064a\u0629 \u0639\u0644\u0649 \u0636\u0631\u0648\u0631\u0629 \u0627\u0644\u0648\u0642\u0627\u064a\u0629 \u0645\u0646 \u0627\u0644\u062a\u062e\u0644\u062e\u0644 \u0627\u0644\u0639\u0638\u0645\u064a \u0627\u0644\u0645\u062d\u0631\u0651\u0636 \u0628\u0645\u062b\u0628\u0637\u0627\u062a \u0627\u0644\u0623\u0631\u0648\u0645\u0627\u062a\u0627\u0632 \u0648\u0639\u0644\u0627\u062c\u0647\u0627 \u0625\u0646 \u062d\u062f\u062b\u062a\u060c \u062d\u064a\u062b \u064a\u0634\u062f\u0651\u062f \u0627\u0644\u062f\u0644\u064a\u0644 \u0627\u0644\u0625\u0631\u0634\u0627\u062f\u064a \u0644\u0645\u0646\u0638\u0645\u0629 \u0627\u0644\u0635\u062d\u0629 \u0627\u0644\u0639\u0627\u0644\u0645\u064a\u0629 (<\/strong>(WHO<\/strong> \u0648\u0627\u0644\u0645\u0624\u0633\u0633\u0629 \u0627\u0644\u0648\u0637\u0646\u064a\u0651\u0629 \u0644\u062a\u062e\u0644\u062e\u0644 \u0627\u0644\u0639\u0638\u0627\u0645 National Osteoporosis Foundation<\/strong> (<\/strong>(NOF<\/strong> \u0639\u0644\u0649 \u0625\u064a\u062a\u0627\u0621 \u0627\u0644\u0645\u0631\u0636\u0649 \u0645\u0636\u0627\u062f\u0627\u062a \u0627\u0631\u062a\u0634\u0627\u0641 \u0627\u0644\u0639\u0638\u0645 (\u0627\u0644\u0641\u0648\u0633\u0641\u0648\u0646\u0627\u062a \u0627\u0644\u062b\u0646\u0627\u0626\u064a\u0629) \u0648\u0627\u0644\u0643\u0627\u0644\u0633\u064a\u0648\u0645 \u0627\u0644\u0639\u0646\u0635\u0631\u064a \u0628\u062c\u0631\u0639\u0629 (800<\/strong>–1200<\/strong> \u0645\u0644\u063a) \u0648\u0641\u064a\u062a\u0627\u0645\u064a\u0646D3<\/sub><\/strong> \u00a0\u0628\u062c\u0631\u0639\u0629 (1000<\/strong> \u2013 2000<\/strong> (IU<\/strong>. 18<\/sup>\u060c<\/sup>19<\/sup><\/span><\/p>\n

\"\"<\/span><\/p>\n

\"\"<\/span><\/p>\n

\u0627\u0646\u0635\u0628\u062a \u0627\u0644\u062c\u0647\u0648\u062f \u0641\u064a \u0647\u0630\u0627 \u0627\u0644\u0628\u062d\u062b \u0639\u0644\u0649 \u0627\u062e\u062a\u0628\u0627\u0631 \u0641\u0631\u0636\u064a\u0651\u0629 \u0625\u0645\u0643\u0627\u0646\u064a\u0651\u0629 \u062a\u0623\u0645\u064a\u0646 \u0632\u064a\u0627\u062f\u0629 \u0641\u064a \u0627\u0644\u0641\u0639\u0651\u0627\u0644\u064a\u0651\u0629 \u0627\u0644\u0648\u0642\u0627\u0626\u064a\u0651\u0629 \u0648\u0627\u0644\u0639\u0644\u0627\u062c\u064a\u0651\u0629 \u0644\u0644\u0628\u0631\u0646\u0627\u0645\u062c \u0627\u0644\u0639\u0644\u0627\u062c\u064a \u0627\u0644\u0645\u0648\u0635\u0649 \u0628\u0647 \u0645\u0646 \u0642\u0628\u0644 WHO \u0648 NOF\u0644\u062a\u062f\u0628\u064a\u0631 \u062a\u062e\u0644\u062e\u0644 \u0627\u0644\u0639\u0638\u0627\u0645 \u0627\u0644\u0645\u062d\u062f\u062b \u0623\u0648 \u0627\u0644\u0645\u0635\u0627\u062d\u0628 \u0644\u0640 AIs \u0641\u064a 48 \u0645\u0646 \u0645\u0631\u064a\u0636\u0627\u062a \u0633\u0631\u0637\u0627\u0646 \u0627\u0644\u062b\u062f\u064a \u0627\u0644\u0644\u0627 \u0646\u0642\u064a\u0644\u064a\u060c \u0648\u0630\u0644\u0643 \u0628\u0625\u0636\u0627\u0641\u0629 \u062c\u0631\u0639\u0629 \u0645\u0631\u062a\u0641\u0639\u0629 \u0645\u0646 \u0641\u064a\u062a\u0627\u0645\u064a\u0646 D3<\/sub> (5000 \u0648\u062d\u062f\u0629 \u062f\u0648\u0644\u064a\u0651\u0629). <\/span>\u0642\u0645\u0646\u0627 \u0628\u0639\u0634\u0648\u0623\u0629 \u0627\u0644\u0645\u0631\u064a\u0636\u0627\u062a \u0627\u0644\u0644\u0627\u062a\u064a \u062d\u0642\u0642\u0646 \u0645\u0639\u0627\u064a\u064a\u0631 \u0627\u0644\u0627\u0634\u062a\u0645\u0627\u0644 \u0641\u064a \u0630\u0631\u0627\u0639\u064a \u0627\u0644\u062f\u0651\u0631\u0627\u0633\u0629\u060c \u0645\u0645\u0627 \u0636\u0645\u0646 \u0639\u062f\u0645 \u0648\u062c\u0648\u062f \u0641\u0648\u0627\u0631\u0642 \u0630\u0627\u062a \u062f\u0644\u0627\u0644\u0629 \u0625\u062d\u0635\u0627\u0626\u064a\u0651\u0629 \u0628\u064a\u0646 \u0627\u0644\u0645\u0631\u064a\u0636\u0627\u062a \u0641\u064a \u0627\u0644\u062e\u0637\u064a\u0646 \u0627\u0644\u0639\u0644\u0627\u062c\u064a\u064a\u0646 \u0633\u0648\u0627\u0621 \u0645\u0646 \u062d\u064a\u062b \u0627\u0644\u0645\u062a\u062b\u0627\u0628\u062a\u0627\u062a \u0627\u0644\u0643\u064a\u0645\u064a\u0627\u0626\u064a\u0629 \u0627\u0644\u062d\u064a\u0648\u064a\u0629 \u0644\u0644\u062f\u0651\u0631\u0627\u0633\u0629 \u0623\u0645 \u0627\u0644\u0645\u0648\u0627\u0635\u0641\u0627\u062a \u0627\u0644\u0628\u062f\u0626\u064a\u0651\u0629 \u0627\u0644\u062f\u064a\u0645\u0648\u063a\u0631\u0627\u0641\u064a\u0629 \u0648\u0627\u0644\u0639\u0627\u0645\u0629\u060c \u0628\u0627\u0633\u062a\u062b\u0646\u0627\u0621 \u0648\u062c\u0648\u062f \u0641\u0627\u0631\u0642 \u0627\u062d\u0635\u0627\u0626\u064a (<\/strong>p<\/em><\/strong>=0.03<\/strong>)<\/strong> \u0645\u0646 \u062d\u064a\u062b \u062a\u0648\u0632\u0651\u0639 \u0627\u0644\u0645\u0631\u064a\u0636\u0627\u062a \u0648\u0641\u0642 \u062a\u0635\u0646\u064a\u0641\u0627\u062a \u0627\u0644\u0628\u062f\u0627\u0646\u0629 \u0627\u0644\u0645\u0639\u062a\u0645\u062f\u0629 \u0639\u0644\u0649 \u0627\u0644\u0640 BMI. <\/span>\u0628\u064a\u0651\u0646\u062a \u0646\u062a\u0627\u0626\u062c \u062f\u0631\u0627\u0633\u062a\u0646\u0627 \u0627\u0631\u062a\u0641\u0627\u0639 \u0646\u0633\u0628 \u0627\u0646\u062a\u0634\u0627\u0631 \u0642\u0644\u0651\u0629 \u0627\u0644\u0639\u0638\u0645 \u0623\u0648 \u062a\u062e\u0644\u062e\u0644\u0647 (91.7%) <\/strong>\u0644\u062f\u0649 \u0627\u0644\u0639\u064a\u0651\u0646\u0629 \u0627\u0644\u0645\u062f\u0631\u0648\u0633\u0629 \u0645\u0646 \u0645\u0631\u064a\u0636\u0627\u062a \u0633\u0631\u0637\u0627\u0646 \u0627\u0644\u062b\u062f\u064a \u0627\u0644\u0644\u0627 \u0646\u0642\u064a\u0644\u064a \u0627\u0644\u0645\u0639\u0627\u0644\u062c\u0627\u062a \u0628\u0640 AIs \u0641\u064a \u0643\u0644\u0627 \u0627\u0644\u0645\u0633\u062a\u0634\u0641\u064a\u064a\u0646 \u0627\u0644\u0644\u0630\u064a\u0646 \u0623\u062c\u0631\u064a\u062a \u0641\u064a\u0647\u0645\u0627 \u0627\u0644\u062f\u0651\u0631\u0627\u0633\u0629 (\u0645\u0633\u062a\u0634\u0641\u0649 \u0627\u0644\u0628\u064a\u0631\u0648\u0646\u064a \u0627\u0644\u062c\u0627\u0645\u0639\u064a \u0648\u0645\u0633\u062a\u0634\u0641\u0649 \u0627\u0644\u0647\u0644\u0627\u0644 \u0627\u0644\u0623\u062d\u0645\u0631)\u060c \u0648\u0641\u0627\u0642\u062a \u0647\u0630\u0647 \u0627\u0644\u0646\u0651\u0633\u0628\u0629 \u0641\u064a \u0627\u0644\u0645\u0631\u064a\u0636\u0627\u062a \u0627\u0644\u0633\u0648\u0631\u064a\u0651\u0627\u062a \u0646\u0633\u0628\u0629 \u0627\u0644\u0627\u0646\u062a\u0634\u0627\u0631 \u0627\u0644\u062a\u064a \u0648\u0631\u062f\u062a \u0641\u064a \u062f\u0631\u0627\u0633\u0629 Lomax, A. \u00a0\u00a0\u0648\u0632\u0645\u0644\u0627\u0626\u0647 (<\/strong>2013<\/strong>) \u0644\u0645\u0631\u064a\u0636\u0627\u062a \u0627\u0633\u062a\u0631\u0627\u0644\u064a\u0627\u062a, <\/strong>\u062d\u064a\u062b \u0628\u0644\u063a\u062a \u0646\u0633\u0628\u0629 \u0627\u0646\u062a\u0634\u0627\u0631 \u0642\u0644\u0629\/ \u062a\u062e\u0644\u062e\u0644 \u0627\u0644\u0639\u0638\u0627\u0645 \u0644\u062f\u0649 \u0645\u0631\u064a\u0636\u0627\u062a \u0633\u0631\u0637\u0627\u0646 \u062b\u062f\u064a \u062d\u062f\u064a\u062b \u0627\u0644\u0643\u0634\u0641 \u0627\u0644\u0644\u0627\u062a\u064a \u062a\u062c\u0627\u0648\u0632\u0646 \u0633\u0646 \u0627\u0644\u0627\u064a\u0627\u0633 57.8% \u060c \u0645\u0645\u0651\u0627 \u064a\u0628\u0631\u0647\u0646 \u0639\u0644\u0649 \u0627\u0644\u062d\u0627\u062c\u0629 \u0627\u0644\u0645\u0627\u0633\u0651\u0629 \u0644\u0625\u064a\u0644\u0627\u0621 \u0645\u0631\u064a\u0636\u0627\u062a\u0646\u0627 \u0627\u0647\u062a\u0645\u0627\u0645\u0627\u064b \u0643\u0628\u064a\u0631\u0627\u064b \u0644\u0645\u0627 \u064a\u0645\u062b\u0644\u0646\u0647 \u0645\u0646 \u062c\u0645\u0647\u0631\u0629 \u0639\u0627\u0644\u064a\u0629 \u0627\u0644\u0627\u062e\u062a\u0637\u0627\u0631.20 <\/sup><\/span>\u0648\u0645\u0646 \u062c\u0647\u0629 \u062b\u0627\u0646\u064a\u0629, \u0623\u0638\u0647\u0631\u062a \u062f\u0631\u0627\u0633\u062a\u0646\u0627 \u0628\u0634\u0643\u0644\u0650 \u062c\u0644\u064a\u0651\u0650 \u0648\u0648\u0627\u0636\u062d \u0627\u0644\u0627\u0633\u062a\u062e\u062f\u0627\u0645 \u0627\u0644\u0645\u062a\u0648\u0627\u0636\u0639 \u0648\u0627\u0644\u062e\u062c\u0648\u0644 \u0644\u0644\u0645\u062a\u0645\u0645\u0627\u062a \u0627\u0644\u063a\u0630\u0627\u0626\u064a\u0629 (\u0627\u0644\u062d\u0627\u0648\u064a\u0629 \u0639\u0644\u0649 \u0627\u0644\u0641\u064a\u062a\u0627\u0645\u064a\u0646 D3<\/sub> \u0648\u0627\u0644\u0643\u0627\u0644\u0633\u064a\u0648\u0645) \u0648\u0645\u0636\u0627\u062f\u0627\u062a \u0627\u0631\u062a\u0634\u0627\u0641 \u0627\u0644\u0639\u0638\u0645 \u0627\u0644\u0630\u064a \u0644\u0645 \u064a\u062a\u062c\u0627\u0648\u0632 11% \u0644\u062f\u0649 \u0647\u0630\u0647 \u0627\u0644\u062c\u0645\u0647\u0631\u0629, \u0645\u0627 \u064a\u062d\u062b\u0651\u0646\u0627 \u0639\u0644\u0649 \u0627\u064a\u0644\u0627\u0621 \u0627\u0644\u0623\u0647\u0645\u064a\u0629 \u0641\u064a \u062a\u062f\u0628\u064a\u0631 \u0647\u0630\u0647 \u0627\u0644\u062d\u0627\u0644\u0627\u062a \u0628\u0627\u0644\u0635\u0648\u0631\u0629 \u0627\u0644\u0623\u0641\u0636\u0644 \u0645\u0646 \u0642\u0628\u0644 \u0641\u0631\u064a\u0642 \u0645\u062a\u0639\u062f\u062f \u0627\u0644\u0627\u062e\u062a\u0635\u0627\u0635\u0627\u062a \u0644\u062a\u062d\u0631\u0651\u064a \u0641\u0639\u0651\u0627\u0644\u064a\u0629 \u0627\u0644\u0645\u0642\u0627\u0631\u0628\u0629 \u0627\u0644\u0639\u0644\u0627\u062c\u064a\u0651\u0629 \u0627\u0644\u0645\u0642\u062a\u0631\u062d\u0629 \u0628\u062f\u0631\u0627\u0633\u062a\u0646\u0627, \u0648\u0625\u064a\u0644\u0627\u0621 \u0645\u0632\u064a\u062f \u0645\u0646 \u0627\u0644\u0627\u0647\u062a\u0645\u0627\u0645 \u0628\u0627\u0644\u0645\u0631\u064a\u0636\u0627\u062a \u0645\u0646 \u062d\u064a\u062b \u0646\u0634\u0631 \u0627\u0644\u0648\u0639\u064a \u0627\u0644\u0635\u0651\u062d\u064a \u0644\u0644\u0648\u0642\u0627\u064a\u0629 \u0645\u0646 \u062a\u062e\u0644\u062e\u0644 \u0627\u0644\u0639\u0638\u0627\u0645 \u0627\u0644\u0645\u062d\u0651\u062f\u062b\u0629 \u0628\u0645\u062b\u0628\u0637\u0627\u062a \u0627\u0644\u0623\u0631\u0648\u0645\u0627\u062a\u0627\u0632 AIs. <\/span>\u0643\u0645\u0627 \u0633\u0644\u0651\u0637\u062a \u062f\u0631\u0627\u0633\u062a\u0646\u0627 \u0627\u0644\u0636\u0648\u0621 \u0639\u0644\u0649 \u0646\u0633\u0628 \u0627\u0644\u0627\u0646\u062a\u0634\u0627\u0631 \u0627\u0644\u0645\u0631\u062a\u0641\u0639\u0629 (83.4%) \u0644\u0646\u0642\u0635 \u0641\u064a\u062a\u0627\u0645\u064a\u0646 D3<\/sub> \u0648\u0639\u0648\u0632\u0647 \u0644\u062f\u0649 \u0627\u0644\u0645\u0631\u064a\u0636\u0627\u062a \u0627\u0644\u0645\u0634\u0627\u0631\u0643\u0627\u062a \u0641\u064a \u0627\u0644\u062f\u0631\u0627\u0633\u0629 \u0648\u0630\u0644\u0643 \u0627\u0639\u062a\u0645\u0627\u062f\u0627\u064b \u0639\u0644\u0649 \u062a\u0635\u0646\u064a\u0641 \u0627\u0644\u0640 IOM\u060c \u062d\u064a\u062b \u0641\u0627\u0642\u062a \u0646\u0633\u0628\u0629 \u0639\u0648\u0632 \u0641\u064a\u062a\u0627\u0645\u064a\u0646 D \u0627\u0644\u0640 97%\u060c \u0648\u0630\u0644\u0643 \u0644\u062f\u0649 \u0627\u0639\u062a\u0645\u0627\u062f \u0627\u0644\u0642\u064a\u0645\u0629 \u0627\u0644\u062d\u062f\u064a\u0651\u0629 \u0627\u0644\u0623\u0639\u0644\u0649 \u0645\u0646 \u062a\u0631\u0627\u0643\u064a\u0632 \u0641\u064a\u062a\u0627\u0645\u064a\u0646 D (25(OH)D \u226530 \u0646\u063a\/\u0645\u0644)\u060c \u0644\u062a\u0639\u0631\u064a\u0641 \u062d\u062f\u0651 \u0627\u0644\u0643\u0641\u0627\u064a\u0629 \u0644\u062f\u0649 \u0634\u0631\u064a\u062d\u0629 \u0645\u0631\u064a\u0636\u0627\u062a \u0633\u0631\u0637\u0627\u0646 \u0627\u0644\u062b\u062f\u064a \u0627\u0644\u0644\u0627\u0646\u0642\u064a\u0644\u064a \u0627\u0644\u0645\u0639\u0627\u0644\u062c\u0627\u062a \u0628\u0640 AIs\u060c \u0648\u0647\u0648 \u0645\u0627 \u0627\u062a\u0641\u0642 \u0645\u0639 \u0627\u0644\u0646\u062a\u064a\u062c\u0629 \u0627\u0644\u062a\u064a \u062e\u0644\u0635\u062a \u0644\u0647\u0627 \u062f\u0631\u0627\u0633\u0629 Imtaiz \u00a0\u0648\u0632\u0645\u0644\u0627\u0626\u0647 2012\u060c \u062d\u064a\u062b \u0628\u0644\u063a\u062a \u0646\u0633\u0628\u0629 \u0627\u0644\u0639\u0648\u0632 <\/strong>95.6% \u0644\u062f\u0649 \u0645\u0631\u064a\u0636\u0627\u062a\u064d \u0628\u0627\u0643\u0633\u062a\u0627\u0646\u064a\u0627\u062a \u0645\u0634\u062e\u0651\u0635\u0627\u062a \u062d\u062f\u064a\u062b\u0627\u064b \u0628\u0633\u0631\u0637\u0627\u0646 \u062b\u062f\u064a\u060c \u0641\u064a \u062d\u064a\u0646 \u0643\u0627\u0646\u062a \u0646\u0633\u0628\u0629 \u0627\u0644\u0639\u0648\u0632 \u0644\u062f\u0649 \u0645\u062c\u0645\u0648\u0639\u0629 \u0627\u0644\u0634\u0627\u0647\u062f \u0644\u0646\u0633\u0627\u0621 \u0633\u0644\u064a\u0645\u0627\u062a 77% (69 \u0633\u064a\u062f\u0629) \u0648\u0628\u0641\u0627\u0631\u0642 \u0627\u062d\u0635\u0627\u0626\u064a p<0.001\u060c \u0645\u0627 \u064a\u062f\u0644 \u0639\u0644\u0649 \u0623\u0647\u0645\u064a\u0629 \u062a\u0642\u064a\u064a\u0645 \u0648\u062a\u062f\u0628\u064a\u0631 \u0639\u0648\u0632 \u0641\u064a\u062a\u0627\u0645\u064a\u0646 D \u0644\u062f\u0649 \u0645\u0631\u064a\u0636\u0627\u062a \u0633\u0631\u0637\u0627\u0646 \u0627\u0644\u062b\u062f\u064a \u0627\u0644\u0644\u0627\u0646\u0642\u064a\u0644\u064a \u0627\u0644\u0645\u0639\u0627\u0644\u062c\u0627\u062a \u0628\u0645\u062b\u0628\u0637\u0627\u062a \u0627\u0644\u0623\u0631\u0648\u0645\u0627\u062a\u0627\u0632 AIs.21 <\/sup><\/span>\u0648\u0627\u0644\u062c\u062f\u064a\u0631 \u0628\u0627\u0644\u0627\u0647\u062a\u0645\u0627\u0645 \u0627\u0644\u0639\u0644\u0627\u0642\u0629 \u0627\u0644\u0639\u0643\u0633\u064a\u0629 \u0627\u0644\u0645\u0644\u0627\u062d\u0638\u0629 \u0628\u064a\u0646 \u0627\u0646\u062e\u0641\u0627\u0636 \u0645\u062a\u0648\u0633\u0637 \u0642\u064a\u0645 25(OH)D \u0648\u0627\u0631\u062a\u0641\u0627\u0639 \u0642\u064a\u0645 \u0645\u0634\u0639\u0631 \u0643\u062a\u0644\u0629 \u0627\u0644\u062c\u0633\u0645 BMI \u0644\u062f\u0649 \u0628\u062f\u0621 \u0627\u0644\u062f\u0631\u0627\u0633\u0629 \u0641\u0643\u0627\u0646 \u0645\u062a\u0648\u0633\u0637 \u0642\u064a\u0645 25(OH)D \u0644\u062f\u0649 \u0627\u0644\u0645\u0631\u064a\u0636\u0627\u062a \u0627\u0644\u0628\u062f\u064a\u0646\u0627\u062a (BMI\u226530) 9.65<\/u> \u0646\u063a\/\u0645\u0644\u060c \u0645\u0642\u0627\u0631\u0646\u0629 \u0628\u0645\u0633\u062a\u0648\u064a\u0627\u062a \u00a014.07<\/u> \u0646\u063a\/\u0645\u0644 \u0644\u0644\u0645\u0631\u064a\u0636\u0627\u062a \u0627\u0644\u0623\u0642\u0644 \u0648\u0632\u0646\u0627\u064b (BMI <30)\u060c \u0648\u0647\u0648\u00a0 \u0645\u0627 \u0627\u062a\u0633\u0642 \u0645\u0639 \u0646\u062a\u0627\u0626\u062c \u062f\u0631\u0627\u0633\u0629 Vashi \u00a0\u0648\u0632\u0648\u0645\u0644\u0627\u0626\u0647 (2011)\u060c \u062d\u064a\u062b \u0643\u0627\u0646 \u0645\u062a\u0648\u0633\u0637 \u0642\u064a\u0645 25(OH)D \u0644\u062f\u0649 \u0627\u0644\u0645\u0631\u064a\u0636\u0627\u062a \u0637\u0628\u064a\u0639\u064a\u0627\u062a \u0627\u0644\u0648\u0632\u0646 24.6<\/u> \u0646\u063a\/\u0645\u0644\u060c \u0628\u0627\u0644\u0645\u0642\u0627\u0628\u0644 \u0627\u0646\u062e\u0641\u0636\u062a \u0645\u0633\u062a\u0648\u064a\u0627\u062a 25(OH)D \u0644\u062f\u0649 \u0627\u0644\u0645\u0631\u064a\u0636\u0627\u062a \u0627\u0644\u0628\u062f\u064a\u0646\u0627\u062a (BMI\u226530) \u0644\u062d\u062f\u0648\u062f 17.9<\/u> \u0646\u063a\/\u0645\u0644\u060c \u0648\u0642\u062f \u062e\u0644\u0635\u062a \u062a\u0644\u0643 \u0627\u0644\u062f\u0631\u0627\u0633\u0629 \u0625\u0644\u0649 \u0623\u0646\u0651 \u0643\u0644 \u0627\u0631\u062a\u0641\u0627\u0639 \u0628\u0642\u064a\u0645\u0629 \u0627\u0644\u0640 (BMI) \u0628\u0645\u0642\u062f\u0627\u0631 1 \u0643\u063a\/\u06452 <\/sup>\u064a\u062a\u0631\u0627\u0641\u0642 \u0645\u0639 \u0627\u0646\u062e\u0641\u0627\u0636 \u0628\u0642\u064a\u0645\u0629 25(OH)D \u0628\u0645\u0642\u062f\u0627\u0631 0.42 \u0646\u063a\/\u0645\u0644\u060c \u0645\u0645\u0651\u0627 \u064a\u0633\u062a\u062f\u0639\u064a \u0627\u0647\u062a\u0645\u0627\u0645\u0627\u064b \u0623\u0643\u0628\u0631 \u0628\u062d\u0627\u0644\u0629 \u0641\u064a\u062a\u0627\u0645\u064a\u0646 D \u0644\u062f\u0649 \u0634\u0631\u064a\u062d\u0629 \u0627\u0644\u0645\u0631\u064a\u0636\u0627\u062a \u0627\u0644\u0628\u062f\u064a\u0646\u0627\u062a (BMI\u226530). 22 <\/sup><\/span>\u0648\u0628\u064a\u0651\u0646\u062a \u0646\u062a\u0627\u0626\u062c \u0627\u0644\u062a\u0651\u062d\u0644\u064a\u0644 \u0627\u0644\u0627\u062d\u0635\u0627\u0626\u064a\u0651 \u0644\u0644\u0628\u064a\u0627\u0646\u0627\u062a \u0628\u0639\u062f \u0627\u0646\u062a\u0647\u0627\u0621 \u0627\u0644\u062f\u0631\u0627\u0633\u0629 \u0625\u0644\u0649 \u0648\u062c\u0648\u062f \u0627\u0632\u062f\u064a\u0627\u062f \u0641\u064a \u0627\u0644\u0643\u062b\u0627\u0641\u0629 \u0627\u0644\u0645\u0639\u062f\u0646\u064a\u0629 \u0644\u0644\u0639\u0638\u0645 (BMD) \u0628\u0627\u0644\u0641\u0642\u0631\u0627\u062a \u0627\u0644\u0642\u0637\u0646\u064a\u0629 \u0628\u0646\u0633\u0628\u0629 (1.96%) \u0628\u0627\u0644\u062e\u0637 \u0627\u0644\u0639\u0644\u0627\u062c\u064a \u0627\u0644\u0623\u0648\u0644 \u0645\u0642\u0627\u0631\u0646\u0629 \u0645\u0639 (5.88%) \u0628\u0627\u0644\u062e\u0637 \u0627\u0644\u0639\u0644\u0627\u062c\u064a \u0627\u0644\u062b\u0627\u0646\u064a \u0645\u0627 \u064a\u0634\u064a\u0631 \u0625\u0644\u0649 \u0641\u0639\u0627\u0644\u064a\u0629 \u062a\u0622\u0632\u0631\u064a\u0629 \u0644\u0644\u0641\u064a\u062a\u0627\u0645\u064a\u0646 D3<\/sub> \u0628\u062c\u0631\u0639\u0629 (IU5800) \u0645\u0639 \u0627\u0644\u0643\u0627\u0644\u0633\u064a\u0648\u0645 \u0648\u0627\u0644\u0641\u0633\u0641\u0648\u0646\u0627\u062a \u0627\u0644\u062b\u0646\u0627\u0626\u064a\u0629 (\u0631\u064a\u0632\u062f\u0631\u0648\u0646\u0627\u062a) \u0641\u064a \u0625\u062d\u062f\u0627\u062b \u062a\u062d\u0633\u0651\u0646 \u0645\u0644\u0645\u0648\u0633\u064d \u0648\u062e\u0644\u0627\u0644 \u0645\u062f\u0629 \u0632\u0645\u0646\u064a\u0651\u0629 \u0642\u0635\u064a\u0631\u0629 \u0641\u064a \u0627\u0644\u0643\u062b\u0627\u0641\u0629 \u0627\u0644\u0645\u0639\u062f\u0646\u064a\u0651\u0629 \u0644\u0644\u0639\u0638\u0645 \u0648\u0628\u0634\u0643\u0644 \u064a\u0639\u0627\u0643\u0633 \u0627\u0644\u062a\u0623\u062b\u064a\u0631\u0627\u062a \u0627\u0644\u0633\u0644\u0628\u064a\u0629 \u0644\u0645\u062b\u0628\u0637\u0627\u062a \u0627\u0644\u0623\u0631\u0648\u0645\u0627\u062a\u0627\u0632 (AIs). <\/span>\u0648\u0645\u0646 \u0627\u0644\u0644\u0627\u0641\u062a \u0644\u0644\u0646\u0638\u0631 \u0623\u0646\u0651 \u0627\u0632\u062f\u064a\u0627\u062f \u0645\u062a\u0648\u0633\u0637 \u0642\u064a\u0645 \u0627\u0644\u0641\u0631\u0648\u0642\u0627\u062a \u0641\u064a \u0627\u0644\u0645\u0633\u062a\u0648\u064a\u0627\u062a \u0627\u0644\u0645\u0635\u0644\u064a\u0651\u0629 \u0644\u0640 25(OH)D \u0628\u064a\u0646 \u0628\u062f\u0621 \u0627\u0644\u0634\u0651\u0648\u0637 \u0627\u0644\u0639\u0644\u0627\u062c\u064a \u0648\u062e\u062a\u0627\u0645\u0647 \u0643\u0627\u0646 \u0645\u062e\u062a\u0644\u0641\u0627\u064b \u0628\u064a\u0646 \u0627\u0644\u062e\u0637\u064a\u0646 \u0627\u0644\u0639\u0644\u0627\u062c\u064a\u0646 \u0644\u062f\u0649 \u0627\u0644\u0627\u0644\u062a\u0632\u0627\u0645 \u0644\u0645\u062f\u0629 \u0642\u0635\u064a\u0631\u0629 \u0648\u0645\u062a\u0634\u0627\u0628\u0647\u0627\u064b \u062a\u0642\u0631\u064a\u0628\u0627\u064b \u0644\u062f\u0649 \u0627\u0644\u0627\u0644\u062a\u0632\u0627\u0645 \u0644\u0645\u062f\u0629 \u0637\u0648\u064a\u0644\u0629\u060c \u0623\u064a \u0623\u0646 \u0627\u0644\u062c\u0631\u0639\u0629 \u0627\u0644\u0639\u0627\u0644\u064a\u0629 (5800IU) \u0643\u0627\u0646\u062a \u0623\u0633\u0631\u0639 \u0645\u0646 \u0627\u0644\u062c\u0631\u0639\u0629 \u0627\u0644\u0645\u0646\u062e\u0641\u0636\u0629 (800 IU) \u0641\u064a \u0631\u0641\u0639 \u0645\u0633\u062a\u0648\u064a\u0627\u062a 25(OH)D \u0641\u064a \u0627\u0644\u0645\u0635\u0644 \u0639\u0644\u0649 \u0627\u0644\u0645\u062f\u0649 \u0627\u0644\u0642\u0635\u064a\u0631\u060c \u0644\u0643\u0646 \u0627\u0644\u0645\u062b\u064a\u0631 \u0644\u0644\u0627\u0647\u062a\u0645\u0627\u0645 \u062b\u0628\u0627\u062a \u0645\u062a\u0648\u0633\u0637 \u0642\u064a\u0645 \u0627\u0644\u0641\u0631\u0648\u0642\u0627\u062a (\u0627\u0644\u062a\u0631\u0627\u0643\u064a\u0632 \u0628\u0639\u062f \u062a\u0644\u0642\u064a \u0627\u0644\u0639\u0644\u0627\u062c-\u0627\u0644\u062a\u0631\u0627\u0643\u064a\u0632 \u0627\u0644\u0628\u062f\u0626\u064a\u0651\u0629) \u0628\u064a\u0646 \u0627\u0644\u0645\u0633\u062a\u0648\u064a\u0627\u062a \u0627\u0644\u0628\u0644\u0627\u0632\u0645\u064a\u0629 \u0644\u0640\u00a0 25(OH)D \u0639\u0644\u0649 23 \u0646\u063a\/\u0645\u0644 \u062d\u062a\u0649 \u0628\u0639\u062f \u0627\u0644\u0627\u0644\u062a\u0632\u0627\u0645 \u0628\u0627\u0644\u0639\u0644\u0627\u062c \u0644\u0645\u062f\u0629 \u0637\u0648\u064a\u0644\u0629\u060c \u0645\u0627 \u062c\u0639\u0644\u0646\u0627 \u0646\u0633\u062a\u0646\u062a\u062c \u0623\u0646\u0651 \u0627\u0644\u062c\u0631\u0639\u0629 \u0627\u0644\u0639\u0627\u0644\u064a\u0629 \u0645\u0646 \u0641\u064a\u062a\u0627\u0645\u064a\u0646 D3<\/sub> (5800 IU) \u0633\u0627\u0639\u062f\u062a \u0639\u0644\u0649 \u0625\u062d\u062f\u0627\u062b \u062a\u062d\u0633\u0646 \u0633\u0631\u064a\u0639 \u0644\u062a\u0631\u0643\u064a\u0632\u00a0 25(OH)D \u062e\u0644\u0627\u0644 \u0641\u062a\u0631\u0629 \u0642\u0635\u064a\u0631\u0629\u060c \u062b\u0645 \u0627\u064f\u062a\u0628\u0639\u062a \u0647\u0630\u0647 \u0627\u0644\u0645\u0631\u062d\u0644\u0629 \u0628\u0645\u0631\u062d\u0644\u0629 \u062b\u0628\u0627\u062a \u0641\u064a \u0627\u0644\u062a\u0631\u0627\u0643\u064a\u0632, \u0623\u064a \u0623\u0646 \u0627\u0644\u0639\u0644\u0627\u0642\u0629 (\u0628\u064a\u0646 \u0627\u0644\u062a\u0631\u0643\u064a\u0632 \u0648\u0627\u0644\u0632\u0645\u0646) \u062a\u0635\u0628\u062d \u063a\u064a\u0631 \u062e\u0637\u064a\u0629 \u0639\u0646\u062f \u062a\u062c\u0627\u0648\u0632 \u062a\u0631\u0627\u0643\u064a\u0632 25(OH)D \u0644\u0639\u062a\u0628\u0629 30 \u0646\u063a\/\u0645\u0644, \u0648\u0647\u0648 \u0645\u0627 \u0627\u062a\u0641\u0642 \u0645\u0639 \u062f\u0631\u0627\u0633\u0629 \u00a0Cannell \u00a0\u0648\u0632\u0645\u0644\u0627\u0626\u0647<\/em> (<\/em>2008) \u062d\u064a\u062b \u0643\u0627\u0646\u062a \u062c\u0631\u0639\u0629 2000 \u00a0\u0648\u062d\u062f\u0629 \u062f\u0648\u0644\u064a\u0651\u0629 (IU) \u064a\u0648\u0645\u064a\u0627\u064b \u0643\u0627\u0641\u064a\u0629\u064c \u0644\u0644\u0648\u0635\u0648\u0644 \u0628\u062a\u0631\u0643\u064a\u0632 25(OH)D \u0625\u0644\u0649 \u062d\u062f\u0648\u062f 30 \u0646\u063a\/\u0645\u0644 \u0641\u064a \u062d\u0627\u0644 \u0643\u0627\u0646 \u0627\u0644\u062a\u0631\u0643\u064a\u0632 \u0627\u0644\u0628\u062f\u0626\u064a 10 \u0646\u063a\/\u0645\u0644\u060c \u0625\u0644\u0651\u0627 \u0623\u0646\u0651\u0647\u0627 \u0648\u0628\u0627\u0644\u0645\u0642\u0627\u0628\u0644 \u062a\u062e\u0641\u0642 \u0641\u064a \u0632\u064a\u0627\u062f\u0629 \u0627\u0644\u0645\u0633\u062a\u0648\u064a\u0627\u062a \u0627\u0644\u0628\u0644\u0627\u0632\u0645\u064a\u0629 \u0627\u0644\u0628\u062f\u0626\u064a\u0629 \u0645\u0646 30 \u0646\u063a\/\u0645\u0644 \u0644\u062d\u062f\u0648\u062f 50 \u0646\u063a\/\u0645\u0644\u060c \u062d\u062a\u0649 \u0648\u0625\u0646 \u0627\u0633\u062a\u0639\u0645\u0644\u062a \u0644\u0645\u062f\u0629 \u0632\u0645\u0646\u064a\u0629 \u0637\u0648\u064a\u0644\u0629 . 13 <\/sup><\/span>\u0648\u0641\u064a \u0633\u064a\u0627\u0642 \u0645\u062a\u0635\u0644 \u0623\u0641\u0636\u0649 \u0627\u0644\u062e\u0637 \u0627\u0644\u0639\u0644\u0627\u062c\u064a \u0627\u0644\u062b\u0627\u0646\u064a \u0644\u0632\u064a\u0627\u062f\u0629 \u0646\u0633\u0628\u0629 \u0627\u0644\u0645\u0631\u064a\u0636\u0627\u062a \u0627\u0644\u0644\u0648\u0627\u062a\u064a \u062d\u0642\u0642\u0646 \u0627\u0644\u062a\u0631\u0643\u064a\u0632 \u0627\u0644\u0645\u062b\u0627\u0644\u064a \u0627\u0644\u0645\u0646\u0634\u0648\u062f (OH)D25 \u226530 \u0646\u063a\/\u0645\u0644 \u0628\u0646\u0633\u0628\u0629 \u0641\u0627\u0642\u062a \u0627\u0644\u0640 75% (19 \u0645\u0631\u064a\u0636\u0629)\u060c \u0641\u064a \u062d\u064a\u0646 \u0644\u0645 \u062a\u062a\u062c\u0627\u0648\u0632 \u0646\u0633\u0628\u0629 \u0627\u0644\u0645\u0631\u064a\u0636\u0627\u062a \u0627\u0644\u0644\u0648\u0627\u062a\u064a \u0648\u0635\u0644\u0646 \u0627\u0644\u0649 \u0627\u0644\u062a\u0631\u0643\u064a\u0632 \u0627\u0644\u0645\u062b\u0627\u0644\u064a 52% (12 \u0645\u0631\u064a\u0636\u0629) \u0641\u064a \u0627\u0644\u062e\u0637 \u0627\u0644\u0639\u0644\u0627\u062c\u064a \u0627\u0644\u0623\u0648\u0644\u060c \u0627\u0644\u0623\u0645\u0631 \u0627\u0644\u0630\u064a \u064a\u0628\u0631\u0647\u0646 \u0639\u0644\u0649 \u0623\u0647\u0645\u064a\u0629 \u0627\u0644\u062c\u0631\u0639\u0629 \u0627\u0644\u0639\u0627\u0644\u064a\u0629 \u0645\u0646 \u0641\u064a\u062a\u0627\u0645\u064a\u0646 D3<\/sub> (5000 IU) \u0644\u0645\u062f\u0629 \u062a\u062a\u0631\u0627\u0648\u062d \u0628\u064a\u0646 2-12 \u0634\u0647\u0631\u0627\u064b \u0641\u064a \u0625\u0639\u0627\u062f\u0629 \u0645\u0644\u0621 \u0645\u062e\u0627\u0632\u0646 \u0627\u0644\u062c\u0633\u0645 \u0645\u0646 \u0641\u064a\u062a\u0627\u0645\u064a\u0646 D3<\/sub> \u0648\u062a\u062d\u0642\u064a\u0642 \u0627\u0644\u062a\u0631\u0643\u064a\u0632 \u0627\u0644\u0645\u062b\u0627\u0644\u064a (OH)D25 \u226530 \u0646\u063a\/\u0645\u0644 \u0644\u0646\u0633\u0628\u0629 \u0645\u0631\u064a\u0636\u0627\u062a \u0633\u0631\u0637\u0627\u0646 \u062b\u062f\u064a \u0644\u0627\u0646\u0642\u064a\u0644\u064a \u0645\u0639\u0627\u0644\u062c\u0627\u062a \u0628\u0640 AIs\u060c \u0648\u0647\u0648 \u0645\u0627 \u0627\u062a\u0641\u0642 \u0645\u0639 \u062a\u0648\u0635\u064a\u0627\u062a \u0645\u062c\u0645\u0648\u0639\u0629 \u0627\u0644\u0639\u0645\u0644 \u0627\u0644\u0645\u0634\u062a\u0631\u0643\u0629 \u0644\u062c\u0645\u0639\u064a\u062a\u064a \u0627\u0644\u0645\u0639\u0627\u062f\u0646 \u0648\u0627\u0644\u0639\u0638\u0645 \u0627\u0644\u0627\u0633\u062a\u0631\u0627\u0644\u064a\u0629 \u0648\u0627\u0644\u0646\u064a\u0648\u0632\u064a\u0644\u0627\u0646\u062f\u064a\u0629Australian and New Zealand Bone and Mineral Society \u0648\u062c\u0645\u0639\u064a\u0629 \u0627\u0644\u063a\u062f\u062f \u0627\u0644\u0635\u0651\u0645 \u0627\u0644\u0627\u0633\u062a\u0631\u0627\u0644\u064a\u0629 Endocrine Society of Australia \u00a0\u0644\u0639\u0627\u0645 2012 \u0641\u064a \u062a\u062f\u0628\u064a\u0631 \u0639\u0648\u0632 \u0641\u064a\u062a\u0627\u0645\u064a\u0646 \u00a0D3\u0648\u0627\u0644\u062a\u064a \u0623\u0643\u0651\u062f\u062a \u0639\u0644\u0649 \u0636\u0631\u0648\u0631\u0629 \u0625\u064a\u062a\u0627\u0621 \u062c\u0631\u0639\u0627\u062a \u0639\u0627\u0644\u064a\u0629 \u0645\u0646 \u0641\u064a\u062a\u0627\u0645\u064a\u0646 D3<\/sub> (3000-5000) IU \u0644\u0641\u062a\u0631\u0627\u062a \u062a\u062a\u0631\u0627\u0648\u062d \u0628\u064a\u0646 6-12 \u0623\u0633\u0628\u0648\u0639 \u0644\u0625\u0639\u0627\u062f\u0629 \u0645\u0644\u0621 \u0645\u062e\u0627\u0632\u0646 \u0627\u0644\u062c\u0633\u0645 \u0645\u0646 \u0641\u064a\u062a\u0627\u0645\u064a\u0646 D3<\/sub>. 23 <\/sup><\/span>\u062a\u062f\u0639\u0645 \u0646\u062a\u0627\u0626\u062c \u062f\u0631\u0627\u0633\u062a\u0646\u0627 \u0627\u0644\u062d\u0627\u0644\u064a\u0651\u0629 \u062a\u062d\u0633\u0651\u0646 \u0642\u064a\u0645 \u0627\u0644\u0643\u062b\u0627\u0641\u0629 \u0627\u0644\u0639\u0638\u0645\u064a\u0629 \u0628\u0645\u0642\u062f\u0627\u0631 \u0641\u0627\u0642 \u0627\u0644\u0636\u0639\u0641 \u0644\u062f\u0649 \u0634\u0631\u064a\u062d\u0629 \u0627\u0644\u0645\u0631\u064a\u0636\u0627\u062a \u0627\u0644\u0644\u0648\u0627\u062a\u064a \u0628\u0644\u063a\u0646 \u0627\u0644\u062a\u0631\u0643\u064a\u0632 \u0627\u0644\u0645\u062b\u0627\u0644\u064a (OH)D25 \u226530 \u0646\u063a\/\u0645\u0644 \u0645\u0642\u0627\u0631\u0646\u0629 \u0645\u0639 \u0634\u0631\u064a\u062d\u0629 \u0627\u0644\u0645\u0631\u064a\u0636\u0627\u062a \u0627\u0644\u0644\u0648\u0627\u062a\u064a \u0644\u0645 \u064a\u0628\u0644\u063a\u0646 \u0627\u0644\u062a\u0631\u0643\u064a\u0632 \u0627\u0644\u0645\u0646\u0634\u0648\u062f\u060c \u0645\u0627 \u064a\u0624\u0643\u062f \u0623\u0647\u0645\u064a\u0629 \u0627\u0633\u062a\u062e\u062f\u0627\u0645 \u0627\u0644\u062c\u0631\u0639\u0627\u062a \u0627\u0644\u0639\u0627\u0644\u064a\u0629 \u0645\u0646 \u0641\u064a\u062a\u0627\u0645\u064a\u0646 D3<\/sub> \u0641\u064a \u0645\u0639\u0627\u0644\u062c\u0629 \u062a\u062e\u0644\u062e\u0644 \u0627\u0644\u0639\u0638\u0627\u0645 \u0627\u0644\u0645\u062d\u062f\u062b\u0629 \u0628\u0645\u062b\u0628\u0637\u0627\u062a \u0627\u0644\u0623\u0631\u0648\u0645\u0627\u062a\u0627\u0632 \u0648\u0627\u0644\u0648\u0642\u0627\u064a\u0629 \u0645\u0646\u0647.<\/span><\/p>\n

\u0627\u0644\u0627\u0633\u062a\u0646\u062a\u0627\u062c\u0627\u062a <\/strong>Conclusions<\/strong><\/span><\/p>\n

\u0628\u064a\u0651\u0646\u062a \u0646\u062a\u0627\u0626\u062c \u062f\u0631\u0627\u0633\u062a\u0646\u0627 \u0627\u0631\u062a\u0641\u0627\u0639 \u0646\u0633\u0628 \u0627\u0646\u062a\u0634\u0627\u0631 \u0642\u0644\u0651\u0629 \u0627\u0644\u0639\u0638\u0645\u00a0 \u0623\u0648 \u062a\u062e\u0644\u062e\u0644\u0647 \u0648\u0639\u062f\u0645 \u0643\u0641\u0627\u064a\u0629 \u0641\u064a\u062a\u0627\u0645\u064a\u0646 D3<\/sub> \u0623\u0648 \u0639\u0648\u0632\u0647 \u0644\u062f\u0649 \u062c\u0645\u0647\u0631\u0629 \u0645\u0631\u064a\u0636\u0627\u062a \u0633\u0631\u0637\u0627\u0646 \u0627\u0644\u062b\u062f\u064a \u0627\u0644\u0644\u0627\u0646\u0642\u064a\u0644\u064a \u0627\u0644\u0645\u0639\u0627\u0644\u062c\u0627\u062a \u0628\u0645\u062b\u0628\u0651\u0637\u0627\u062a \u0627\u0644\u0623\u0631\u0648\u0645\u0627\u062a\u0627\u0632 \u0641\u064a \u0645\u0633\u062a\u0634\u0641\u064a\u0627\u062a\u0646\u0627\u060c \u0645\u0645\u0651\u0627 \u064a\u062f\u0651\u0644\u0644 \u0639\u0644\u0649 \u0623\u0647\u0645\u064a\u0629 \u0625\u064a\u0644\u0627\u0621 \u062c\u0645\u0647\u0631\u0629 \u0645\u0631\u064a\u0636\u0627\u062a \u0633\u0631\u0637\u0627\u0646 \u0627\u0644\u062b\u062f\u064a \u0627\u0644\u0644\u0627\u0646\u0642\u0627\u0626\u0644\u064a \u0627\u0644\u0645\u0639\u0627\u0644\u062c\u0627\u062a \u0628\u0645\u062b\u0628\u0637\u0627\u062a \u0627\u0644\u0623\u0631\u0648\u0645\u0627\u062a\u0627\u0632 \u0645\u0632\u064a\u062f\u0627\u064b \u0645\u0646 \u0627\u0644\u062f\u0631\u0627\u0633\u0627\u062a \u0627\u0644\u0633\u0631\u064a\u0631\u064a\u0629 \u0648\u0627\u0644\u0631\u0639\u0627\u064a\u0629 \u0627\u0644\u0635\u062d\u064a\u0629 \u0648\u0627\u0644\u062d\u0631\u0635 \u0639\u0644\u0649 \u0627\u0633\u062a\u062e\u062f\u0627\u0645 \u0645\u062a\u0645\u0645\u0627\u062a \u0627\u0644\u0643\u0627\u0644\u0633\u064a\u0648\u0645 \u0648\u0627\u0644\u0641\u064a\u062a\u0627\u0645\u064a\u0646 D3<\/sub> \u0644\u062a\u062d\u0633\u064a\u0646 \u062c\u0648\u062f\u0629 \u0627\u0644\u062d\u064a\u0627\u0629 \u0648\u0645\u0646\u0639 \u0643\u0633\u0648\u0631 \u0627\u0644\u062a\u062e\u0644\u062e\u0644 \u0627\u0644\u0639\u0638\u0645\u064a \u0648\u0632\u064a\u0627\u062f\u0629 \u0645\u0637\u0627\u0648\u0639\u0629 \u0627\u0644\u0645\u0631\u064a\u0636 \u0644\u0645\u062a\u0627\u0628\u0639\u0629 \u0627\u0644\u0639\u0644\u0627\u062c \u0628\u0645\u062b\u0628\u0637\u0627\u062a \u0627\u0644\u0623\u0631\u0648\u0645\u0627\u062a\u0627\u0632. <\/span>\u0643\u0645\u0627 \u0648\u0636\u0651\u062d\u062a \u0627\u0644\u062f\u0631\u0627\u0633\u0629 \u0641\u0639\u0627\u0644\u064a\u0629 \u0625\u0636\u0627\u0641\u0629 \u062c\u0631\u0639\u0629 \u0639\u0627\u0644\u064a\u0629 \u0645\u0646 \u0641\u064a\u062a\u0627\u0645\u064a\u0646 D3<\/sub> \u0644\u0644\u062e\u0637 \u0627\u0644\u0639\u0644\u0627\u062c\u064a \u0627\u0644\u0645\u062a\u0628\u0639 \u0628\u062a\u062f\u0628\u064a\u0631 \u062a\u062e\u0644\u062e\u0644 \u0627\u0644\u0639\u0638\u0627\u0645 \u0627\u0644\u0645\u0635\u0627\u062d\u0628 \u0644\u0644\u0639\u0644\u0627\u062c \u0628\u0645\u062b\u0628\u0637\u0627\u062a \u0627\u0644\u0623\u0631\u0648\u0645\u0627\u062a\u0627\u0632 \u0645\u0646 \u062d\u064a\u062b \u062a\u062d\u0633\u064a\u0646 \u0642\u064a\u0645 \u0645\u062a\u062b\u0627\u0628\u062a\u0627\u062a \u0627\u0644\u0643\u062b\u0627\u0641\u0629 \u0627\u0644\u0639\u0638\u0645\u064a\u0629 (T-Score\u060c Z-Score\u060cBMD) \u0628\u0627\u0644\u0641\u0642\u0631\u0627\u062a \u0627\u0644\u0642\u0637\u0646\u064a\u0629 \u0648\u0639\u0646\u0642 \u0627\u0644\u0641\u062e\u062f \u0648\u062a\u0635\u062d\u064a\u062d \u0645\u0633\u062a\u0648\u064a\u0627\u062a (OH)D25 \u0627\u0644\u0645\u0635\u0644\u064a\u0629. <\/span>\u0628\u0631\u0647\u0646\u062a \u0627\u0644\u062f\u0631\u0627\u0633\u0629 \u0627\u0644\u062d\u0627\u0644\u064a\u0651\u0629 \u0639\u0644\u0649 \u0641\u0639\u0627\u0644\u064a\u0629 \u0623\u0639\u0644\u0649 \u0644\u0644\u062c\u0631\u0639\u0629 \u0627\u0644\u0639\u0627\u0644\u064a\u0629 \u0628\u0627\u0644\u0645\u0642\u0627\u0631\u0646\u0629 \u0645\u0639 \u0627\u0644\u062c\u0631\u0639\u0629 \u0627\u0644\u0645\u0646\u062e\u0641\u0636\u0629 \u0645\u0646 \u0641\u064a\u062a\u0627\u0645\u064a\u0646 D3<\/sub> \u0644\u062f\u0649 \u0627\u0644\u0627\u0644\u062a\u0632\u0627\u0645 \u0628\u0647\u0627 \u0644\u0641\u062a\u0631\u0629 \u0632\u0645\u0646\u064a\u0629 \u0623\u0637\u0648\u0644 (\u062a\u062a\u062c\u0627\u0648\u0632 \u0627\u0644\u0640 6 \u0623\u0634\u0647\u0631) \u0645\u0646 \u062d\u064a\u062b \u062a\u062d\u0633\u0651\u0646 \u0642\u064a\u0645 \u0645\u062a\u062b\u0627\u0628\u062a\u0627\u062a \u0627\u0644\u0643\u062b\u0627\u0641\u0629 \u0627\u0644\u0639\u0638\u0645\u064a\u0629 (T-Score\u060c Z-Score\u060cBMD)\u060c \u0644\u0643\u0646 \u062f\u0648\u0646 \u0623\u0646 \u064a\u0631\u0627\u0641\u0642 \u0630\u0644\u0643 \u0632\u064a\u0627\u062f\u0629 \u0645\u0648\u0627\u0632\u064a\u0629 \u0641\u064a \u0627\u0644\u0645\u0633\u062a\u0648\u064a\u0627\u062a \u0627\u0644\u0645\u0635\u0644\u064a\u0651\u0629 \u0644\u0640 (OH)D25 \u0648\u0627\u0644\u062a\u064a \u062d\u0627\u0641\u0638\u062a \u0639\u0644\u0649 \u062b\u0628\u0627\u062a\u0647\u0627 \u0644\u062f\u0649 \u0627\u0644\u0627\u0633\u062a\u062e\u062f\u0627\u0645 \u0627\u0644\u0645\u0637\u0648\u0651\u0644.<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"

\u0627\u0644\u0645\u0642\u062f\u0645\u0629 Introduction: \u064a\u064f\u0639\u062f\u0651 \u0633\u0631\u0637\u0627\u0646 \u0627\u0644\u062b\u062f\u064a \u0623\u062d\u062f \u0623\u0647\u0645 \u0627\u0644\u0645\u0634\u0643\u0644\u0627\u062a \u0627\u0644\u0635\u062d\u064a\u0629 \u0627\u0644\u062a\u064a \u062a\u0648\u0627\u062c\u0647 \u0646\u0633\u0627\u0621 \u0627\u0644\u0639\u0627\u0644\u0645\u060c \u0646\u0638\u0631\u0627\u064b \u0644\u0643\u0648\u0646\u0647 \u0623\u0643\u062b\u0631 \u0627\u0644\u062e\u0628\u0627\u062b\u0627\u062a \u062a\u0634\u062e\u064a\u0635\u0627\u064b (11.7%)\u060c \u0648\u0627\u0644\u0645\u0633\u0628\u0651\u0628 \u0627\u0644\u0623\u0648\u0644 \u0644\u0644\u0648\u0641\u064a\u0627\u062a…
\u0627\u0642\u0631\u0623 \u0627\u0644\u0645\u0632\u064a\u062f<\/a><\/p>\n","protected":false},"author":1,"featured_media":448,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[136],"tags":[],"class_list":["post-100","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-136","issue-134","volume-9"],"acf":[],"_links":{"self":[{"href":"https:\/\/pharmjournal.asscph.com\/index.php?rest_route=\/wp\/v2\/posts\/100","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/pharmjournal.asscph.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/pharmjournal.asscph.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/pharmjournal.asscph.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/pharmjournal.asscph.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=100"}],"version-history":[{"count":0,"href":"https:\/\/pharmjournal.asscph.com\/index.php?rest_route=\/wp\/v2\/posts\/100\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/pharmjournal.asscph.com\/index.php?rest_route=\/wp\/v2\/media\/448"}],"wp:attachment":[{"href":"https:\/\/pharmjournal.asscph.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=100"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/pharmjournal.asscph.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=100"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/pharmjournal.asscph.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=100"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}