{"id":1607,"date":"2024-09-01T18:04:06","date_gmt":"2024-09-01T18:04:06","guid":{"rendered":"https:\/\/pharmjournal.asscph.com\/?p=1607"},"modified":"2025-01-06T10:01:43","modified_gmt":"2025-01-06T10:01:43","slug":"%d8%aa%d9%82%d9%8a%d9%8a%d9%85-%d9%85%d8%b3%d8%aa%d9%88%d9%8a%d8%a7%d8%aa-%d8%a7%d9%84%d9%83%d9%8a%d9%85%d9%8a%d8%b1%d9%8a%d9%86-%d8%a7%d9%84%d9%85%d8%b5%d9%84%d9%8a%d8%a9-%d9%84%d8%af%d9%89-%d8%b3","status":"publish","type":"post","link":"https:\/\/pharmjournal.asscph.com\/?p=1607","title":{"rendered":"\u062a\u0642\u064a\u064a\u0645 \u0645\u0633\u062a\u0648\u064a\u0627\u062a \u0627\u0644\u0643\u064a\u0645\u064a\u0631\u064a\u0646 \u0627\u0644\u0645\u0635\u0644\u064a\u0629 \u0644\u062f\u0649 \u0633\u0648\u0631\u064a\u064a\u0646 \u0633\u0643\u0631\u064a\u064a\u0646 \u0645\u0646 \u0627\u0644\u0646\u0645\u0637 2 \u0648\u0639\u0644\u0627\u0642\u062a\u0647\u0627 \u0645\u0639 \u0627\u0644\u0633\u0645\u0646\u0629 \u0627\u0644\u062d\u0634\u0648\u064a\u0629"},"content":{"rendered":"

\u0627\u0644\u0645\u0642\u062f\u0645\u0629<\/strong><\/span><\/p>\n

\u064a\u064f\u0639\u0651\u062f\u064f \u0627\u0644\u0633\u0643\u0631\u064a \u0645\u0646 \u0627\u0644\u0646\u0645\u0637 2 (Type 2 Diabetes Mellitus T2DM) \u0623\u064e\u062d\u062f \u0627\u0644\u0623\u0645\u0631\u0627\u0636 \u0627\u0644\u0627\u0633\u062a\u0642\u0644\u0627\u0628\u064a\u0629 \u0627\u0644\u0645\u064f\u0632\u0645\u0646\u0629 \u0627\u0644\u0645\u062a\u0632\u0627\u064a\u062f\u0629 \u0639\u0627\u0644\u0645\u064a\u0627\u064b\u060c \u0648\u0627\u0644\u062a\u064a \u062a\u064e\u062a\u0635\u0641 \u0628\u0627\u0631\u062a\u0641\u0627\u0639 \u0645\u0633\u062a\u0648\u064a\u0627\u062a \u063a\u0644\u0648\u0643\u0648\u0632 \u0627\u0644\u062f\u0645 \u0627\u0644\u0646\u0627\u062c\u0645 \u0639\u0646 \u0646\u0650\u0642\u0635 \u0625\u0650\u0641\u0631\u0627\u0632 \u0627\u0644\u0623\u0646\u0633\u0648\u0644\u064a\u0646 \u0623\u0648 \u0645\u0642\u0627\u0648\u0645\u0629 \u0627\u0644\u0623\u0646\u0633\u0648\u0644\u064a\u0646. \u064a\u062a\u0633\u0628\u0628 \u0627\u0644\u0633\u0643\u0631\u064a \u0628\u0645\u062c\u0645\u0648\u0639\u0629 \u0645\u062a\u0646\u0648\u0639\u0629 \u0645\u0646 \u0627\u0644\u0645\u064f\u0636\u0627\u0639\u0641\u0627\u062a \u0628\u0645\u0627 \u0641\u064a\u0647\u0627 \u0627\u0644\u0623\u0645\u0631\u0627\u0636 \u0627\u0644\u0642\u0644\u0628\u064a\u0629 \u0627\u0644\u0648\u0639\u0627\u0626\u064a\u0629 \u0648\u0627\u0644\u0633\u0643\u062a\u0629 \u0627\u0644\u062f\u0645\u0627\u063a\u064a\u0629 \u0648\u0627\u0644\u0627\u0639\u062a\u0644\u0627\u0644 \u0627\u0644\u0643\u0644\u0648\u064a \u0648\u0627\u0644\u0628\u0635\u0631\u064a \u0627\u0644\u0633\u0643\u0631\u064a \u0648\u063a\u064a\u0631\u0647\u0627(1).\u062a\u064f\u0639\u0631\u0651\u064e\u0641 \u0627\u0644\u0633\u0645\u0646\u0629 \u0628\u0643\u0648\u0646\u0647\u0627 \u062a\u0631\u0627\u0643\u0645 \u0645\u0641\u0631\u0637 \u0623\u0648 \u063a\u064a\u0631 \u0637\u0628\u064a\u0639\u064a \u0644\u0644\u0623\u0646\u0633\u062c\u0629 \u0627\u0644\u0634\u062d\u0645\u064a\u0629 (2) \u0648\u062a\u064f\u0645\u062b\u0644 \u0623\u062d\u062f \u0639\u0648\u0627\u0645\u0644 \u0627\u0644\u0627\u062e\u062a\u0637\u0627\u0631 \u0627\u0644\u0623\u0633\u0627\u0633\u064a\u0629 \u0644\u0644\u0639\u062f\u064a\u062f \u0645\u0646 \u0627\u0644\u0623\u0645\u0631\u0627\u0636 \u0627\u0644\u0627\u0633\u062a\u0642\u0644\u0627\u0628\u064a\u0629 \u0645\u062b\u0644 (T2DM) [4]. \u064a\u0645\u0643\u0646 \u0627\u0633\u062a\u062e\u062f\u0627\u0645 \u0628\u0639\u0636 \u0627\u0644\u0645\u0646\u0627\u0633\u0628 \u0644\u062a\u0634\u062e\u064a\u0635 \u0627\u0644\u0633\u0645\u0646\u0629 \u0628\u0645\u0627 \u0641\u064a\u0647\u0627 \u0645\u0646\u0633\u0628 \u0643\u062a\u0644\u0629 \u0627\u0644\u062c\u0633\u0645 (Body Mass Index BMI) (3, 4) \u0648\u0645\u062d\u064a\u0637 \u0627\u0644\u062e\u0635\u0631 Waist Circumference WC)) (5). \u062a\u064f\u062d\u0633\u0628\u064f \u0642\u064a\u0645\u0629 (BMI) \u0639\u0628\u0631 \u0627\u0644\u0645\u0639\u0627\u062f\u0644\u0629 \u0627\u0644\u062a\u0627\u0644\u064a\u0629:<\/span><\/p>\n

BMI (kg\/m2<\/sup>) = weight (kg)\/height (m2<\/sup>)\u00a0 \u00a0 \u00a0(6)<\/span><\/p>\n

\u064a\u064f\u0639\u062f\u0651\u064f \u0645\u062d\u064a\u0637 \u0627\u0644\u062e\u0635\u0631 \u0623\u062d\u062f \u0627\u0644\u0645\u0646\u0627\u0633\u0628 \u0627\u0644\u0628\u0633\u064a\u0637\u0629 \u0648\u0627\u0644\u0645\u0645\u062b\u0644\u0629 \u0644\u0644\u062f\u0647\u0648\u0646 \u0627\u0644\u062d\u0634\u0648\u064a\u0629 Visceral Adipose Tissue (VAT) (5)\u060c \u0648\u0642\u062f \u0623\u0648\u0635\u062a \u0645\u0646\u0638\u0645\u0629 \u0627\u0644\u0635\u062d\u0629 \u0627\u0644\u0639\u0627\u0644\u0645\u064a\u0629 (World Health Organization WHO) \u0628\u0627\u0633\u062a\u062e\u062f\u0627\u0645 \u0627\u0644\u0642\u064a\u0645 \u0627\u0644\u062d\u062f\u0650\u0651\u064a\u0629 \u0648\u0647\u064a cm \u00a0102< \u0644\u062f\u0649 \u0627\u0644\u0631\u062c\u0627\u0644 \u0648 cm88< \u0644\u062f\u0649 \u0627\u0644\u0646\u0633\u0627\u0621 (6). \u062a\u0643\u0645\u0646 \u0623\u0647\u0645\u064a\u0651\u064e\u0629 \u0627\u0644\u0623\u0646\u0633\u062c\u0629 \u0627\u0644\u0634\u062d\u0645\u064a\u0629 \u0627\u0644\u062d\u0634\u0648\u064a\u0629 \u0628\u062f\u0648\u0631\u0647\u0627 \u0641\u064a \u0627\u0644\u062d\u0645\u0627\u064a\u0629 \u0644\u0644\u0623\u0639\u0636\u0627\u0621 \u0627\u0644\u062f\u0627\u062e\u0644\u064a\u0629 (7)\u060c \u0644\u0643\u0646\u0651\u064e \u0627\u0650\u062d\u062a\u0648\u0627\u0621\u0647\u0627 \u0639\u0644\u0649 \u0639\u062f\u062f \u0645\u0631\u062a\u0641\u0639 \u0645\u0646 \u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u0634\u062d\u0645\u064a\u0629 \u0627\u0644\u0645\u0642\u0627\u0648\u0645\u0629 \u0644\u0644\u0623\u0646\u0633\u0648\u0644\u064a\u0646 \u0648\u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u0645\u0646\u0627\u0639\u064a\u0629 \u0627\u0644\u0627\u0644\u062a\u0647\u0627\u0628\u064a\u0629 (2) \u0648\u0627\u0650\u0645\u062a\u0644\u0627\u0643\u0647\u0627 \u0644\u0646\u0634\u0627\u0637 \u0627\u0633\u062a\u0642\u0644\u0627\u0628\u064a \u0645\u064f\u0631\u062a\u0641\u0639 \u0648\u0641\u0639\u0627\u0644\u064a\u0629 \u0634\u062f\u064a\u062f\u0629 \u0641\u064a \u062d\u064e\u0644\u0651\u0650 \u0627\u0644\u062f\u0651\u064f\u0647\u0648\u0646 (8) \u064a\u064e\u062c\u0639\u0644\u0647\u0627 \u0645\u0635\u062f\u0631\u0627\u064b \u0645\u0647\u0645\u0627\u064b \u0644\u0644\u0639\u062f\u064a\u062f \u0645\u0646 \u0627\u0644\u0628\u0631\u0648\u062a\u064a\u0646\u0627\u062a \u0627\u0644\u0627\u0644\u062a\u0647\u0627\u0628\u064a\u0629 \u0643\u0627\u0644\u0623\u062f\u064a\u0628\u0648\u0643\u064a\u0646\u0627\u062a \u0627\u0644\u0645\u0646\u0634\u0637\u0629 \u0644\u0644\u0627\u0644\u062a\u0647\u0627\u0628 (9). \u0644\u0630\u0644\u0643 \u064a\u0631\u062a\u0628\u0637 \u062a\u0631\u0627\u0643\u0645 (VAT) \u0627\u0644\u062d\u0627\u0635\u0644 \u0641\u064a \u062d\u0627\u0644\u0629 \u0627\u0644\u0633\u0645\u0646\u0629 \u0645\u0639 \u062a\u0637\u0648\u0631 \u0645\u064f\u062e\u062a\u0644\u0641 \u0627\u0644\u0645\u0636\u0627\u0639\u0641\u0627\u062a \u0627\u0644\u0627\u0633\u062a\u0642\u0644\u0627\u0628\u064a\u0629 \u0628\u0645\u0627 \u0641\u064a\u0647\u0627 (T2DM)\u060c \u0645\u0645\u0627 \u064a\u064f\u0641\u064e\u0633\u0651\u0650\u0631\u064f \u0627\u0631\u062a\u0641\u0627\u0639 \u0627\u0644\u0625\u0635\u0627\u0628\u0629 \u0628\u0627\u0644\u0633\u0643\u0631\u064a \u0644\u062f\u0649 \u0627\u0644\u0623\u0641\u0631\u0627\u062f \u0627\u0644\u0628\u062f\u064a\u0646\u064a\u0646 (8, 10). \u0625\u0644\u0649 \u062c\u0627\u0646\u0628 \u0630\u0644\u0643\u060c \u0623\u064e\u0634\u0627\u0631\u062a \u0627\u0644\u062f\u0631\u0627\u0633\u0627\u062a \u0627\u0644\u062d\u062f\u064a\u062b\u0629 \u0625\u0644\u0649 \u0627\u0650\u0632\u062f\u064a\u0627\u062f \u0645\u064f\u0639\u062f\u0651\u064e\u0644 \u0627\u0650\u0646\u062a\u0634\u0627\u0631 \u0627\u0644\u0633\u0643\u0631\u064a \u0644\u062f\u0649 \u0627\u0644\u0623\u0641\u0631\u0627\u062f \u0623\u0633\u0648\u064a\u0627\u0621 \u0627\u0644\u0648\u0632\u0646(11). \u0646\u0638\u0631\u0627\u064b \u0644\u0630\u0644\u0643\u060c \u0642\u064e\u0627\u0645\u062a \u062f\u0631\u0627\u0633\u0627\u062a \u0643\u062b\u064a\u0631\u0629 \u0628\u0645\u064f\u062d\u0627\u0648\u0644\u0629 \u0627\u0644\u0643\u0634\u0641 \u0639\u0646 \u0627\u0644\u0623\u0633\u0628\u0627\u0628 \u0627\u0644\u0645\u0633\u0627\u0647\u0645\u0629 \u0641\u064a \u062a\u0637\u0651\u064f\u0648\u0631 (T2DM) \u0644\u062f\u0649 \u0627\u0644\u0623\u0641\u0631\u0627\u062f \u0627\u0644\u0628\u062f\u064a\u0646\u064a\u0646 \u0648\u0623\u0633\u0648\u064a\u0627\u0621 \u0627\u0644\u0648\u0632\u0646. \u0648\u0642\u062f \u062d\u064f\u062f\u0651\u0650\u062f\u064e \u0627\u0644\u0625\u0650\u0641\u0631\u0627\u0632 \u0627\u0644\u0645\u064f\u062a\u063a\u064a\u0631 \u0644\u0644\u0623\u062f\u064a\u0628\u0648\u0643\u064a\u0646\u0627\u062a \u0644\u062f\u0649 \u0627\u0644\u0623\u0646\u0633\u062c\u0629 \u0627\u0644\u0634\u062d\u0645\u064a\u0629 \u0643\u0623\u064e\u062d\u062f \u0627\u0644\u0639\u064e\u0648\u0627\u0645\u0644 \u0627\u0644\u0645\u064f\u0633\u0627\u0647\u0645\u0629 \u0641\u064a \u0630\u0644\u0643 (11, 12). \u062a\u064f\u0639\u0631\u0641 \u0627\u0644\u0623\u062f\u064a\u0628\u0648\u0643\u064a\u0646\u0627\u062a \u0628\u0643\u0648\u0646\u0647\u0627 \u0628\u0650\u0628\u062a\u064a\u062f\u0627\u062a \u0646\u064e\u0634\u0637\u0629 \u062d\u064a\u0648\u064a\u0627\u064b \u062a\u0624\u062b\u0631 \u0641\u064a \u0627\u0644\u0623\u0639\u0636\u0627\u0621 \u0627\u0644\u0646\u0634\u0637\u0629 \u0627\u0633\u062a\u0642\u0644\u0627\u0628\u064a\u0627\u064b \u0645\u0634\u0627\u0631\u0643\u0629\u064b \u0628\u0630\u0644\u0643 \u0641\u064a \u0645\u062e\u062a\u0644\u0641 \u0627\u0644\u0639\u0645\u0644\u064a\u0627\u062a \u0627\u0644\u062d\u064a\u0648\u064a\u0629 \u0627\u0644\u0623\u0633\u0627\u0633\u064a\u0629 (10)\u060c \u0644\u0630\u0644\u0643 \u0641\u0625\u0646\u0651\u064e \u0627\u0644\u0625\u0641\u0631\u0627\u0632 \u0627\u0644\u0645\u064f\u062a\u063a\u064a\u0631 \u0644\u0647\u0630\u0647 \u0627\u0644\u0628\u0631\u0648\u062a\u064a\u0646\u0627\u062a \u064a\u064f\u0633\u0627\u0647\u0645 \u0628\u0634\u0643\u0644 \u0631\u0626\u064a\u0633\u064a \u0641\u064a \u0632\u064a\u0627\u062f\u0629 \u0627\u062e\u062a\u0637\u0627\u0631 \u0627\u0644\u0625\u0635\u0627\u0628\u0629 \u0628\u0645\u062c\u0645\u0648\u0639\u0629 \u0645\u062a\u0646\u0648\u0639\u0629 \u0645\u0646 \u0627\u0644\u0623\u0645\u0631\u0627\u0636 \u0627\u0644\u0627\u0633\u062a\u0642\u0644\u0627\u0628\u064a\u0629 \u0627\u0644\u0645\u0631\u062a\u0628\u0637\u0629 \u0628\u0627\u0644\u0633\u0645\u0646\u0629 \u0645\u062b\u0644 (T2DM) (12, 13). \u0625\u0630 \u0627\u062e\u062a\u0644\u0641\u062a \u0627\u0644\u0645\u0633\u062a\u0648\u064a\u0627\u062a \u0627\u0644\u0645\u0635\u0644\u064a\u064e\u0651\u0629 \u0644\u0644\u0623\u062f\u064a\u0628\u0648\u0643\u064a\u0646\u0627\u062a \u0644\u062f\u0649 \u0627\u0644\u0633\u0643\u0631\u064a\u064a\u0646 \u0645\u0646 \u0627\u0644\u0646\u0645\u0637 2 \u0645\u0642\u0627\u0631\u0646\u0629 \u0645\u0639 \u0627\u0644\u0623\u0641\u0631\u0627\u062f \u0627\u0644\u0623\u0635\u062d\u0627\u0621 \u0645\u0639 \u0648\u062c\u0648\u062f \u062a\u064e\u0628\u062f\u0644\u0627\u062a \u0623\u064e\u0643\u062b\u0631 \u0648\u0636\u0648\u062d\u0627\u064b \u0644\u062f\u0649 \u0627\u0644\u0633\u0643\u0631\u064a\u064a\u0646 \u0627\u0644\u0628\u062f\u064a\u0646\u064a\u0646(11). \u064a\u064f\u0639\u062f\u0651\u064f \u0627\u0644\u0643\u064a\u0645\u064a\u0631\u064a\u0646 \u0623\u064e\u062d\u062f \u0623\u0647\u0645 \u0627\u0644\u0623\u062f\u064a\u0628\u0648\u0643\u064a\u0646\u0627\u062a \u062d\u062f\u064a\u062b\u0629 \u0627\u0644\u062f\u0650\u0651\u0631\u0627\u0633\u0629\u060c \u064a\u064f\u0646\u062a\u062c \u0628\u0645\u0633\u062a\u0648\u064a\u0627\u062a \u0645\u0631\u062a\u0641\u0639\u0629 \u0645\u0646 \u0642\u0628\u0644 (VAT) \u0648\u064a\u064f\u0634\u0627\u0631\u0643 \u0641\u064a \u0645\u064f\u062e\u062a\u0644\u0641 \u0627\u0644\u0639\u0645\u0644\u064a\u0627\u062a \u0627\u0644\u062d\u064a\u0648\u064a\u0629 \u0628\u0645\u0627 \u0641\u064a\u0647\u0627 \u062a\u064e\u0643\u0651\u064f\u0648\u0646 \u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u0634\u062d\u0645\u064a\u0629 \u0648\u0647\u0650\u062c\u0631\u0629 \u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u0645\u0646\u0627\u0639\u064a\u0629 \u0648\u062a\u064e\u0634\u0643\u0651\u064f\u0644 \u0627\u0644\u0623\u0648\u0639\u064a\u0629 \u0627\u0644\u062f\u0645\u0648\u064a\u0629 \u0648\u0627\u0633\u062a\u0642\u0644\u0627\u0628 \u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u0634\u062d\u0645\u064a\u0629 \u0639\u0628\u0631 \u062a\u062d\u0641\u064a\u0632\u0647 \u0644\u062a\u062d\u0644\u0651\u0650\u0644 \u0627\u0644\u062f\u064f\u0651\u0647\u0648\u0646 (14) \u0648\u0644\u0627\u0644\u062a\u0647\u0627\u0628 \u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u0634\u062d\u0645\u064a\u0629 \u0648\u0645\u0642\u0627\u0648\u0645\u0629 \u0627\u0644\u0623\u0646\u0633\u0648\u0644\u064a\u0646 (15-17). \u0644\u0630\u0644\u0643 \u0642\u062f \u064a\u064e\u0643\u0648\u0646 \u0627\u0644\u0643\u064a\u0645\u064a\u0631\u064a\u0646 \u062d\u0644\u0642\u0629 \u0648\u0635\u0644 \u0628\u064a\u0646 \u0627\u0644\u0633\u0645\u0646\u0629 \u0648\u0627\u0644\u0633\u0643\u0631\u064a \u0645\u0646 \u0627\u0644\u0646\u0645\u0637 2\u060c \u0648\u0642\u062f \u062f\u064f\u0639\u0645 \u0630\u0644\u0643 \u0628\u0627\u0644\u0639\u062f\u064a\u062f \u0645\u0646 \u0627\u0644\u062f\u0631\u0627\u0633\u0627\u062a \u0627\u0644\u0633\u0631\u064a\u0631\u064a\u0629 \u0648\u0627\u0644\u0645\u062e\u062a\u0628\u0631\u064a\u0629 (17). \u0625\u0630 \u0628\u064e\u064a\u0651\u064e\u0646\u062a \u0627\u0644\u062f\u0631\u0627\u0633\u0627\u062a \u0632\u064a\u0627\u062f\u0629 \u0627\u0644\u062a\u0639\u0628\u064a\u0631 \u0639\u0646 \u0627\u0644\u0643\u064a\u0645\u064a\u0631\u064a\u0646 \u0644\u062f\u0649 \u0625\u0650\u062d\u062f\u0649 \u0627\u0644\u0646\u0645\u0627\u0630\u062c \u0627\u0644\u0641\u0623\u0631\u064a\u0629 Psammomys Obesus\u060c \u0648\u0647\u064a \u0641\u0626\u0631\u0627\u0646 \u0645\u064f\u0635\u0627\u0628\u0629 \u0628\u0627\u0644\u0633\u0645\u0646\u0629 \u0648(T2DM)\u060c \u0648\u0630\u0644\u0643 \u0628\u0627\u0644\u0645\u0642\u0627\u0631\u0646\u0629 \u0645\u0639 \u0641\u0650\u0626\u0631\u0627\u0646 \u0646\u062d\u064a\u0644\u0629 \u063a\u064a\u0631 \u0633\u0643\u0631\u064a\u0651\u064e\u0629 Normoglycemic lean model (18). \u0643\u0645\u0627 \u0644\u064f\u0648\u062d\u0638 \u0627\u0631\u062a\u0641\u0627\u0639 \u0645\u064f\u0633\u062a\u0648\u064a\u0627\u062a \u0627\u0644\u0643\u064a\u0645\u064a\u0631\u064a\u0646 \u0627\u0644\u062f\u0645\u0648\u064a\u0629 \u0644\u062f\u0649 \u0627\u0644\u0641\u0626\u0631\u0627\u0646 \u0627\u0644\u0628\u062f\u064a\u0646\u0629-\u0627\u0644\u0633\u0643\u0631\u064a\u0629 \u0628\u0645\u0642\u062f\u0627\u0631 \u0636\u0639\u0641\u064a\u0646 \u062a\u0642\u0631\u064a\u0628\u0627\u064b \u0645\u0642\u0627\u0631\u0646\u0629\u064b \u0645\u0639 \u062a\u064e\u0631\u0643\u064a\u0632\u0647 \u0644\u062f\u0649 \u0627\u0644\u0641\u0650\u0626\u0631\u0627\u0646 \u0627\u0644\u0639\u0627\u062f\u064a\u0629 (19). \u0648\u0648\u064f\u062c\u062f \u062a\u064e\u0639\u0628\u064a\u0631 \u0645\u0631\u062a\u0641\u0639 \u0639\u0646 \u0627\u0644\u0643\u064a\u0645\u064a\u0631\u064a\u0646 \u0641\u064a \u0627\u0644\u0623\u0646\u0633\u062c\u0629 \u0627\u0644\u0634\u062d\u0645\u064a\u0629 \u0627\u0644\u062d\u0634\u0648\u064a\u0629 \u0644\u062f\u0649 \u0641\u0626\u0631\u0627\u0646 (Male OLETF rats)\u060c \u0648\u0647\u064a \u0623\u062d\u062f \u0627\u0644\u0646\u0645\u0627\u0630\u062c \u0627\u0644\u0645\u062b\u0627\u0644\u064a\u0629 \u0644\u0645\u0642\u0627\u0648\u0645\u0629 \u0627\u0644\u0623\u0646\u0633\u0648\u0644\u064a\u0646 \u0648(T2DM) (20). \u0639\u0644\u0627\u0648\u0629\u064b \u0639\u0644\u0649 \u0630\u0644\u0643\u060c \u0641\u064e\u0627\u0642\u0645 \u0627\u0644\u0643\u064a\u0645\u064a\u0631\u064a\u0646 \u0627\u0644\u0645\u064f\u0631\u062a\u0641\u0639 \u0645\u0646 \u062d\u0627\u0644\u0629 \u0639\u062f\u0645 \u062a\u062d\u0645\u0651\u0644 \u0627\u0644\u063a\u0644\u0648\u0643\u0648\u0632 \u0644\u062f\u0649 \u0627\u0644\u0641\u0626\u0631\u0627\u0646 \u0627\u0644\u0628\u062f\u064a\u0646\u0629-\u0627\u0644\u0633\u0643\u0631\u064a\u0629 \u0639\u0628\u0631 \u062a\u062b\u0628\u064a\u0637\u0647 \u0644\u0642\u0628\u0651\u0637 \u0627\u0644\u063a\u0644\u0648\u0643\u0648\u0632 \u0645\u0646 \u0627\u0644\u0623\u0646\u0633\u062c\u0629 \u0627\u0644\u0634\u062d\u0645\u064a\u0629 \u0648\u0627\u0644\u0639\u0636\u0644\u0627\u062a \u0627\u0644\u0647\u064a\u0643\u0644\u064a\u0629\u060c \u0645\u0645\u0627 \u064a\u064f\u0624\u0643\u0650\u0651\u062f\u064f \u0643\u064e\u0648\u0646 \u0627\u0644\u0643\u064a\u0645\u064a\u0631\u064a\u0646 \u0636\u0627\u0631\u0627\u064b \u0627\u0633\u062a\u0642\u0644\u0627\u0628\u064a\u0627\u064b \u0648\u0645\u064f\u0639\u0632\u0632\u0627\u064b \u0644\u0645\u0642\u0627\u0648\u0645\u0629 \u0627\u0644\u0623\u0646\u0633\u0648\u0644\u064a\u0646 (21). \u0648\u0645\u0646 \u0627\u0644\u0645\u064f\u062b\u064a\u0631 \u0644\u0644\u0627\u0647\u062a\u0645\u0627\u0645\u060c \u062a\u064e\u0641\u0627\u0648\u062a \u0627\u0644\u0645\u0633\u062a\u0648\u064a\u0627\u062a \u0627\u0644\u0645\u0635\u0644\u064a\u0651\u064e\u0629 \u0644\u0644\u0643\u064a\u0645\u064a\u0631\u064a\u0646 \u0644\u062f\u0649 \u0627\u0644\u0628\u0634\u0631 \u0645\u0627 \u0628\u064a\u0646 \u0643\u062a\u0644\u0629 \u0627\u0644\u062c\u0633\u0645 \u0633\u0648\u064a \u0627\u0644\u0648\u0632\u0646 \u0648\u0627\u0644\u0628\u062f\u064a\u0646 (14, 16, 22). \u0625\u0644\u0627\u0651\u064e \u0623\u0646\u0647 \u0644\u0645 \u062a\u062a\u0648\u0641\u0631 \u0625\u0644\u0649 \u0627\u0644\u0622\u0646 \u062f\u0631\u0627\u0633\u0627\u062a \u062d\u0627\u0633\u0645\u0629 \u062d\u0648\u0644 \u0647\u0630\u0647 \u0627\u0644\u0645\u0633\u062a\u0648\u064a\u0627\u062a \u0644\u062f\u0649 \u0627\u0644\u0633\u0643\u0631\u064a\u064a\u0646 \u0645\u0646 \u0627\u0644\u0646\u0645\u0637 2 \u0633\u0648\u0627\u0621 \u0644\u062f\u0649 \u0627\u0644\u0628\u062f\u064a\u0646\u064a\u0646 \u0623\u0648 \u0623\u0633\u0648\u064a\u0627\u0621 \u0627\u0644\u0648\u0632\u0646. \u062d\u064a\u062b \u0625\u0650\u0646\u0651\u064e \u0627\u0644\u0639\u0644\u0627\u0642\u0629 \u0628\u064a\u0646 \u0627\u0644\u0643\u064a\u0645\u064a\u0631\u064a\u0646 \u0648\u0627\u0644\u0633\u0643\u0631\u064a \u0645\u062a\u0646\u0627\u0642\u0636\u0629 \u0648\u0645\u062b\u064a\u0631\u0629 \u0644\u0644\u062c\u062f\u0644\u060c \u0625\u0630 \u0623\u064e\u0634\u0627\u0631\u062a \u0628\u0639\u0636 \u0627\u0644\u062f\u0631\u0627\u0633\u0627\u062a \u0625\u0644\u0649 \u0632\u064a\u0627\u062f\u0629 \u0645\u0633\u062a\u0648\u064a\u0627\u062a\u0647 \u0627\u0644\u0645\u0635\u0644\u064a\u0651\u064e\u0629 \u0644\u062f\u0649 \u0645\u062c\u0645\u0648\u0639\u062a\u064a \u0627\u0644\u0633\u0643\u0631\u064a\u064a\u0646 \u0627\u0644\u0628\u062f\u064a\u0646\u064a\u0646 \u0648\u0627\u0644\u0633\u0643\u0631\u064a\u064a\u0646 \u0623\u0633\u0648\u064a\u0627\u0621 \u0627\u0644\u0648\u0632\u0646 (23) \u0628\u064a\u0646\u0645\u0627 \u0630\u0643\u0631\u062a \u062f\u0631\u0627\u0633\u0627\u062a \u0623\u064f\u062e\u0631\u0649 \u0639\u062f\u0645 \u0648\u062c\u0648\u062f \u0627\u062e\u062a\u0644\u0627\u0641 \u0641\u064a \u0645\u064f\u0633\u062a\u0648\u064a\u0627\u062a\u0647 \u0627\u0644\u0645\u0635\u0644\u064a\u0651\u064e\u0629 \u0644\u062f\u0649 \u0645\u062c\u0645\u0648\u0639\u0629 \u0627\u0644\u0633\u0643\u0631\u064a\u064a\u0646(12). \u0643\u0627\u0646 \u0647\u0630\u0627 \u062d\u064e\u0627\u0641\u0632\u0627\u064b \u0644\u062a\u0642\u064a\u064a\u0645 \u0645\u0633\u062a\u0648\u064a\u0627\u062a \u0627\u0644\u0643\u064a\u0645\u064a\u0631\u064a\u0646 \u0627\u0644\u0645\u0635\u0644\u064a\u0651\u064e\u0629 \u0644\u062f\u0649 \u0627\u0644\u0628\u062f\u064a\u0646\u064a\u0646 \u0648\u0623\u0633\u0648\u064a\u0627\u0621 \u0627\u0644\u0648\u0632\u0646 \u0645\u0646 \u0627\u0644\u0633\u0643\u0631\u064a\u064a\u0646 \u0645\u0646 \u0627\u0644\u0646\u0645\u0637 2 \u0648\u062f\u0631\u0627\u0633\u0629 \u0639\u0644\u0627\u0642\u062a\u0647 \u0645\u0639 \u0645\u062d\u064a\u0637 \u0627\u0644\u062e\u0635\u0631.<\/span><\/p>\n

\u0627\u0644\u0645\u0648\u0627\u062f \u0648\u0627\u0644\u0637\u0631\u0627\u0626\u0642\u00a0<\/strong><\/span><\/p>\n

\u0643\u0627\u0646\u062a \u0627\u0644\u062f\u0631\u0627\u0633\u0629 Cross-Sectional Study: Case-Control. \u0634\u064e\u0645\u0644\u062a \u0627\u0644\u062f\u0631\u0627\u0633\u0629 88 \u0641\u0631\u062f\u0627\u064b\u060c \u0648\u062c\u0631\u0649 \u062a\u0642\u0633\u064a\u0645\u0647\u0645 \u0627\u0639\u062a\u0645\u0627\u062f\u0627\u064b \u0639\u0644\u0649 \u0627\u0644\u0625\u0635\u0627\u0628\u0629 (T2DM) \u0648\u0645\u0646\u0633\u0628 BMI \u0625\u0644\u0649 \u0623\u0631\u0628\u0639\u0629 \u0645\u062c\u0645\u0648\u0639\u0627\u062a:<\/span><\/p>\n

\u0627\u0644\u0645\u062c\u0645\u0648\u0639\u0629 \u0627\u0644\u0623\u0648\u0644\u0649: \u0645\u062c\u0645\u0648\u0639\u0629 \u0627\u0644\u0628\u062f\u064a\u0646\u064a\u0646 \u0627\u0644\u0633\u0643\u0631\u064a\u064a\u0646 \u0645\u0646 \u0627\u0644\u0646\u0645\u0637 2.<\/span><\/p>\n

\u0627\u0644\u0645\u062c\u0645\u0648\u0639\u0629 \u0627\u0644\u062b\u0627\u0646\u064a\u0629: \u0645\u062c\u0645\u0648\u0639\u0629 \u0627\u0644\u0633\u0643\u0631\u064a\u064a\u0646 \u0645\u0646 \u0627\u0644\u0646\u0645\u0637 2 \u0623\u0633\u0648\u064a\u0627\u0621 \u0627\u0644\u0648\u0632\u0646.<\/span><\/p>\n

\u0627\u0644\u0645\u062c\u0645\u0648\u0639\u0629 \u0627\u0644\u062b\u0627\u0644\u062b\u0629: \u0645\u062c\u0645\u0648\u0639\u0629 \u0627\u0644\u0628\u062f\u064a\u0646\u064a\u0646.<\/span><\/p>\n

\u0627\u0644\u0645\u062c\u0645\u0648\u0639\u0629 \u0627\u0644\u0631\u0627\u0628\u0639\u0629: \u0645\u062c\u0645\u0648\u0639\u0629 \u0623\u0633\u0648\u064a\u0627\u0621 \u0627\u0644\u0648\u0632\u0646.<\/span><\/p>\n

\u0634\u064f\u062e\u0651\u0650\u0635\u062a \u0627\u0644\u0633\u0645\u0646\u0629 \u0627\u0639\u062a\u0645\u0627\u062f\u0627\u064b \u0639\u0644\u0649 \u062a\u0635\u0646\u064a\u0641 \u0645\u0646\u0638\u0645\u0629 \u0627\u0644\u0635\u062d\u0629 \u0627\u0644\u0639\u0627\u0644\u0645\u064a\u0629 (WHO) \u0644\u0645\u0646\u0633\u0628 \u0643\u062a\u0644\u0629 \u0627\u0644\u062c\u0633\u0645 (BMI)\u060c \u0625\u0630 \u064a\u064f\u0639\u062f\u0651\u064f \u0627\u0644\u0648\u0632\u0646 \u0637\u0628\u064a\u0639\u064a\u0627\u064b (\u0633\u0648\u064a\u0651 \u0627\u0644\u0648\u0632\u0646) \u0639\u0646\u062f\u0645\u0627 \u064a\u062a\u0631\u0627\u0648\u062d \u0645\u0646\u0633\u0628 BMI \u0644\u062f\u064a\u0647 \u0645\u0646 18.5 \u0625\u0644\u0649 24.9 \u0643\u063a\/\u06452<\/sup>\u060c \u0628\u064a\u0646\u0645\u0627 \u064a\u0639\u0627\u0646\u064a \u0627\u0644\u0641\u0631\u062f \u0645\u0646 \u0627\u0644\u0633\u0645\u0646\u0629 \u0639\u0646\u062f\u0645\u0627 \u064a\u064e\u0628\u0644\u063a \u0645\u0646\u0633\u0628 BMI\u226530 \u0643\u063a\/\u06452<\/sup>(6) . \u0634\u0645\u0644\u062a \u0645\u0639\u0627\u064a\u064a\u0631 \u0627\u0644\u062a\u0636\u0645\u064a\u0646 Inclusion criteria \u0645\u0627 \u064a\u0644\u064a: \u0644\u062f\u0649 \u0645\u062c\u0645\u0648\u0639\u0629 \u0627\u0644\u0633\u0643\u0631\u064a\u064a\u0646: \u0623\u064a \u0645\u0631\u064a\u0636 \u0633\u0643\u0631\u064a \u0645\u0646 \u0627\u0644\u0646\u0645\u0637 2\u060c \u064a\u062a\u0646\u0627\u0648\u0644\u0648\u0646 \u062e\u0627\u0641\u0636\u0627\u062a \u0627\u0644\u063a\u0644\u0648\u0643\u0648\u0632 \u0627\u0644\u0641\u0645\u0648\u064a\u0629\u060c \u0630\u0648\u064a \u0623\u0639\u0645\u0627\u0631 \u0628\u064a\u0646 30-65 \u0639\u0627\u0645\u0627\u064b\u060c \u0648\u0645\u0646 \u0643\u0644\u0627 \u0627\u0644\u062c\u0646\u0633\u064a\u0646. \u0623\u0645\u0651\u064e\u0627 \u0628\u0627\u0644\u0646\u0633\u0628\u0629 \u0644\u0645\u062c\u0645\u0648\u0639\u0629 \u0627\u0644\u0628\u062f\u064a\u0646\u064a\u0646 \u0641\u0642\u062f \u0643\u0627\u0646\u062a \u0645\u0639\u0627\u064a\u064a\u0631 \u0627\u0644\u062a\u0636\u0645\u064a\u0646: \u0623\u0641\u0631\u0627\u062f \u0644\u0627 \u064a\u0639\u0627\u0646\u0648\u0646 \u0645\u0646 \u0623\u064a\u0629 \u0623\u0645\u0631\u0627\u0636 \u0648\u0644\u0627 \u064a\u062a\u0646\u0627\u0648\u0644\u0648\u0646 \u0623\u064a\u0629 \u0623\u062f\u0648\u064a\u0629\u060c \u0645\u062a\u0637\u0627\u0628\u0642\u064a\u0646 \u0645\u0646 \u062d\u064a\u062b \u0627\u0644\u0639\u0645\u0631 \u0648\u0627\u0644\u062c\u0646\u0633 \u0648BMI \u0645\u0639 \u0645\u062c\u0645\u0648\u0639\u0629 \u0627\u0644\u0633\u0643\u0631\u064a\u064a\u0646 \u0627\u0644\u0628\u062f\u064a\u0646\u064a\u0646. \u0628\u064a\u0646\u0645\u0627 \u0643\u0627\u0646\u062a \u0645\u0639\u0627\u064a\u064a\u0631 \u0627\u0644\u062a\u0636\u0645\u064a\u0646 \u0628\u0627\u0644\u0646\u0633\u0628\u0629 \u0644\u0644\u0645\u062c\u0645\u0648\u0639\u0629 \u0623\u0633\u0648\u064a\u0627\u0621 \u0627\u0644\u0648\u0632\u0646\u060c \u0623\u0641\u0631\u0627\u062f \u0623\u0633\u0648\u064a\u0627\u0621 \u0627\u0644\u0648\u0632\u0646 \u0633\u0644\u064a\u0645\u064a\u0646 \u0638\u0627\u0647\u0631\u064a\u0627\u064b \u0644\u0627 \u064a\u0639\u0627\u0646\u0648\u0646 \u0645\u0646 \u0623\u064a\u0629 \u0623\u0645\u0631\u0627\u0636 \u0648\u0644\u0627 \u064a\u062a\u0646\u0627\u0648\u0644\u0648\u0646 \u0623\u064a\u0629 \u0623\u062f\u0648\u064a\u0629\u060c \u0645\u062a\u0637\u0627\u0628\u0642\u064a\u0646 \u0645\u0646 \u062d\u064a\u062b \u0627\u0644\u0639\u0645\u0631 \u0648\u0627\u0644\u062c\u0646\u0633 \u0648BMI \u0645\u0639 \u0645\u062c\u0645\u0648\u0639\u0629 \u0627\u0644\u0633\u0643\u0631\u064a\u064a\u0646 \u0623\u0633\u0648\u064a\u0627\u0621 \u0627\u0644\u0648\u0632\u0646. \u0623\u0645\u0651\u064e\u0627 \u0628\u0627\u0644\u0646\u0633\u0628\u0629 \u0644\u0645\u0639\u0627\u064a\u064a\u0631 \u0627\u0644\u0627\u0633\u062a\u0628\u0639\u0627\u062f Exclusion criteria \u0641\u0634\u0645\u0644\u062a \u0623\u064a \u0645\u0631\u064a\u0636 \u0644\u062f\u064a\u0647 \u0648\u0627\u062d\u062f \u0623\u0648 \u0623\u0643\u062b\u0631 \u0645\u0645\u0627 \u064a\u0644\u064a: \u0627\u0644\u0633\u0643\u0631\u064a \u0645\u0646 \u0627\u0644\u0646\u0645\u0637 1\u060c \u0648\u0627\u0644\u0645\u0635\u0627\u0628\u064a\u0646 \u0628\u0627\u0644\u062d\u0645\u0627\u0636 \u0627\u0644\u0643\u064a\u062a\u0648\u0646\u064a\u060c \u0648\u0627\u0644\u062d\u0648\u0627\u0645\u0644\u060c \u0648\u0627\u0644\u0623\u0641\u0631\u0627\u062f \u0627\u0644\u0630\u064a\u0646 \u064a\u0639\u0627\u0646\u0648\u0646 \u0645\u0646 \u0627\u0644\u0627\u0644\u062a\u0647\u0627\u0628\u0627\u062a \u0627\u0644\u0645\u0632\u0645\u0646\u0629 \u0648\u0627\u0644\u0623\u0645\u0631\u0627\u0636 \u0627\u0644\u0643\u0628\u062f\u064a\u0629\u060c \u0648\u0627\u0644\u0643\u0644\u0648\u064a\u0629\u060c \u0648\u0627\u0644\u0642\u0644\u0628\u064a\u0629\u060c \u0648\u0627\u0644\u0623\u0648\u0631\u0627\u0645 \u0627\u0644\u0645\u0628\u0644\u063a \u0639\u0646\u0647\u0627 \u0630\u0627\u062a\u064a\u0627\u064b\u060c \u0625\u0636\u0627\u0641\u0629 \u0625\u0644\u0649 \u0627\u0644\u0623\u0641\u0631\u0627\u062f \u0642\u064a\u062f \u0627\u0644\u0645\u0639\u0627\u0644\u062c\u0629 \u0628\u0627\u0644\u0623\u0646\u0633\u0648\u0644\u064a\u0646 \u0623\u0648 \u0646\u0627\u0647\u0636\u0627\u062a \u0645\u0633\u062a\u0642\u0628\u0644 (PPAR\u2010\u03b3) \u0623\u0648 \u0628\u0645\u0636\u0627\u062f\u0627\u062a \u0627\u0644\u0627\u0644\u062a\u0647\u0627\u0628 \u0623\u0648 \u0627\u0644\u0645\u0646\u062d\u0641\u0627\u062a \u0623\u0648 \u0623\u062f\u0648\u064a\u0629 \u0627\u0644\u0636\u063a\u0637 \u0623\u0648 \u062e\u0627\u0641\u0636\u0627\u062a \u0627\u0644\u0643\u0648\u0644\u064a\u0633\u062a\u064a\u0631\u0648\u0644 \u0623\u0648 \u062b\u0644\u0627\u062b\u064a\u0627\u062a \u0627\u0644\u063a\u0644\u064a\u0633\u064a\u0631\u064a\u062f. \u062d\u064e\u0635\u0644\u062a \u0647\u0630\u0647 \u0627\u0644\u062f\u0631\u0627\u0633\u0629 \u0639\u0644\u0649 \u0627\u0644\u0645\u0648\u0627\u0641\u0642\u0629 \u0627\u0644\u0623\u062e\u0644\u0627\u0642\u064a\u0629 \u0644\u0644\u0623\u0628\u062d\u0627\u062b \u0627\u0644\u0637\u0628\u064a\u0629 \u0627\u0644\u062d\u064a\u0648\u064a\u0629 \u0641\u064a \u062c\u0627\u0645\u0639\u0629 \u062f\u0645\u0634\u0642 \u0628\u062a\u0627\u0631\u064a\u062e 2022\/1\/29 \u0648\u0628\u0631\u0642\u0645 37-290122-PH\u060c \u0648\u0623\u064f\u062e\u0630\u062a \u0627\u0644\u0645\u0648\u0627\u0641\u0642\u0629 \u0627\u0644\u0645\u0633\u062a\u0646\u064a\u0631\u0629 \u0644\u062c\u0645\u064a\u0639 \u0627\u0644\u0645\u0634\u0627\u0631\u0643\u064a\u0646 \u0648\u062c\u064f\u0645\u0639\u062a \u0639\u064a\u0646\u0627\u062a \u0627\u0644\u062f\u0631\u0627\u0633\u0629 \u0645\u0646 \u0627\u0644\u0639\u064a\u0627\u062f\u0627\u062a \u0627\u0644\u0634\u0627\u0645\u0644\u0629 \u0641\u064a \u062f\u0645\u0634\u0642 \u0641\u064a \u0627\u0644\u0641\u062a\u0631\u0629 \u0627\u0644\u0645\u0645\u062a\u062f\u0629 \u0645\u0627 \u0628\u064a\u0646 \u062d\u0632\u064a\u0631\u0627\u0646 2022 \u0634\u0628\u0627\u0637 2023. \u0623\u064f\u062e\u0630\u062a \u0628\u0639\u0636 \u0627\u0644\u0628\u064a\u0627\u0646\u0627\u062a \u0643\u0627\u0644\u0639\u0645\u0631 \u0648\u0627\u0644\u062c\u0646\u0633 \u0648\u0645\u062f\u0629 \u0627\u0644\u0625\u0635\u0627\u0628\u0629 \u0628\u0627\u0644\u0633\u0643\u0631\u064a (\u0627\u0628\u062a\u062f\u0627\u0621\u064b \u0645\u0646 \u062a\u0634\u062e\u064a\u0635 \u0627\u0644\u0625\u0635\u0627\u0628\u0629) \u0648\u0627\u0644\u0648\u0632\u0646 \u0648\u0627\u0644\u0637\u0648\u0644 \u0648\u0645\u062d\u064a\u0637 \u0627\u0644\u062e\u0635\u0631 \u0645\u0646 \u0643\u0644 \u0645\u0634\u0627\u0631\u0643. \u0642\u0650\u064a\u0633\u062a \u0645\u062d\u064a\u0637 \u0627\u0644\u062e\u0635\u0631 \u0644\u0643\u0644 \u0645\u0634\u0627\u0631\u0643 \u0639\u0628\u0631 \u062a\u062d\u062f\u064a\u062f \u0645\u0646\u062a\u0635\u0641 \u0627\u0644\u0645\u0633\u0627\u0641\u0629 \u0627\u0644\u0623\u0641\u0642\u064a\u0629 \u0628\u064a\u0646 \u0627\u0644\u062d\u0651\u0650\u062f \u0627\u0644\u0623\u062f\u0646\u0649 \u0644\u0644\u0636\u0644\u0639 Costa \u0648\u0642\u0645\u0629 \u0627\u0644\u062d\u0631\u0642\u0641\u064a\u0629 Iliac Crest \u0628\u0627\u0633\u062a\u062e\u062f\u0627\u0645 \u0634\u0631\u064a\u0637 \u063a\u064a\u0631 \u0645\u0631\u0646 (6). \u062b\u0645 \u062d\u064f\u062f\u0651\u0650\u062f\u064e \u0645\u0646\u0633\u0628 BMI \u0644\u0643\u0644 \u0645\u0634\u0627\u0631\u0643. \u0628\u064f\u0632\u0644 5 \u0645\u0644 \u0645\u0646 \u0627\u0644\u062f\u0645 \u0627\u0644\u0648\u0631\u064a\u062f\u064a \u0645\u0646 \u0643\u0644\u0651\u0650 \u0645\u0634\u0627\u0631\u0643 \u0641\u064a \u0647\u0630\u0647 \u0627\u0644\u062f\u0631\u0627\u0633\u0629 \u0628\u0639\u062f \u0635\u064a\u0627\u0645 10-12 \u0633\u0627\u0639\u0629 \u0648\u062c\u064f\u0645\u0639\u062a \u0639\u064a\u0646\u0629 \u0627\u0644\u062f\u0645 \u0639\u0644\u0649 \u0623\u0646\u0628\u0648\u0628 \u062c\u0627\u0641 \u0648\u062a\u064f\u0631\u0643 \u0641\u064a \u062f\u0631\u062c\u0629 \u062d\u0631\u0627\u0631\u0629 \u0627\u0644\u063a\u0631\u0641\u0629 \u062d\u062a\u0649 \u062a\u0645\u0627\u0645 \u0627\u0644\u062a\u062e\u062b\u0631\u060c \u062b\u0645 \u0646\u0628\u0630\u062a \u0627\u0644\u0639\u064a\u0646\u0627\u062a \u0628\u0639\u062f \u062a\u062d\u0631\u064a\u0631 \u0627\u0644\u0639\u0644\u0642\u0629 \u0644\u0645\u062f\u0629 15 \u062f\u0642\u064a\u0642\u0629 \u0628\u0633\u0631\u0639\u0629 1000g\u060c \u0648\u062d\u064f\u0641\u0638\u062a \u0639\u064a\u0646\u0629 \u0627\u0644\u0645\u0635\u0644 \u0628\u0627\u0644\u062a\u062c\u0645\u064a\u062f \u0639\u0646\u062f \u062f\u0631\u062c\u0629 -80C\u00ba \u0625\u0644\u0649 \u062d\u064a\u0646 \u0625\u062c\u0631\u0627\u0621 \u0627\u0644\u0645\u0642\u0627\u064a\u0633\u0629. \u0642\u0650\u064a\u0633\u062a \u0627\u0644\u062a\u0631\u0627\u0643\u064a\u0632 \u0627\u0644\u0645\u0635\u0644\u064a\u0651\u064e\u0629 \u0644\u0644\u0643\u064a\u0645\u064a\u0631\u064a\u0646 \u0628\u0637\u0631\u064a\u0642\u0629 \u0627\u0644\u0627\u0645\u062a\u0632\u0627\u0632 \u0627\u0644\u0645\u0646\u0627\u0639\u064a \u0627\u0644\u0645\u0631\u062a\u0628\u0637 \u0628\u0627\u0644\u0625\u0646\u0632\u064a\u0645 Enzyme-Linked Immunosorbent Assay (ELISA)\u060c \u0648\u0630\u0644\u0643 \u0628\u0627\u0633\u062a\u062e\u062f\u0627\u0645 \u0639\u062a\u064a\u062f\u0629 Quantikine\u00ae ELISA Human Chemerin Immunoassay \u0645\u0646 \u0642\u0628\u0644 \u0634\u0631\u0643\u0629 R&D System \u0648\u0627\u0644\u062a\u064a \u0627\u0639\u062a\u0645\u062f\u062a \u0645\u0628\u062f\u0623 \u0627\u0644\u0634\u0637\u064a\u0631\u0629 \u00a0(ELISA-Sandwich).<\/span><\/p>\n

\u0627\u0644\u062f\u0631\u0627\u0633\u0629 \u0627\u0644\u0625\u062d\u0635\u0627\u0626\u064a\u0629<\/strong><\/span><\/p>\n

\u0627\u0633\u062a\u062e\u062f\u0645 \u0628\u0631\u0646\u0627\u0645\u062c SPSS \u0625\u0635\u062f\u0627\u0631 26 \u0644\u062a\u062d\u0644\u064a\u0644 \u0627\u0644\u0628\u064a\u0627\u0646\u0627\u062a. \u062c\u0631\u0649 \u0627\u0644\u062a\u0639\u0628\u064a\u0631 \u0639\u0646 \u0627\u0644\u0645\u062a\u063a\u064a\u0631\u0627\u062a \u0627\u0644\u0643\u0645\u064a\u0629 \u0627\u0644\u062f\u0627\u062e\u0644\u0629 \u0641\u064a \u0627\u0644\u062f\u0631\u0627\u0633\u0629 \u0628\u0627\u0644\u0645\u062a\u0648\u0633\u0637 \u0627\u0644\u062d\u0633\u0627\u0628\u064a \u00b1 \u0627\u0644\u0627\u0646\u062d\u0631\u0627\u0641 \u0627\u0644\u0645\u0639\u064a\u0627\u0631\u064a. \u0648\u0627\u0633\u062a\u062e\u062f\u0627\u0645 \u0627\u062e\u062a\u0628\u0627\u0631 One-way \u00a0\u00a0ANOVA \u0645\u062a\u0628\u0648\u0639\u0627\u064b \u0628\u0627\u062e\u062a\u0628\u0627\u0631 \u00a0Scheffe \u0645\u0646 \u0623\u062c\u0644 \u062f\u0631\u0627\u0633\u0629 \u0627\u0644\u0641\u0631\u0648\u0642 \u0644\u0644\u0645\u062a\u063a\u064a\u0631\u0627\u062a \u0627\u0644\u0645\u062a\u0648\u0632\u0639\u0629 \u0637\u0628\u064a\u0639\u064a\u0627\u064b \u0644\u062f\u0649 \u0645\u062c\u0645\u0648\u0639\u0627\u062a \u0627\u0644\u062f\u0631\u0627\u0633\u0629\u060c \u0623\u0645\u0651\u064e\u0627 \u0628\u0627\u0644\u0646\u0633\u0628\u0629 \u0644\u0644\u0645\u062a\u063a\u064a\u0631\u0627\u062a \u063a\u064a\u0631 \u0627\u0644\u0645\u062a\u0648\u0632\u0639\u0629 \u0637\u0628\u064a\u0639\u064a\u0627\u064b \u0641\u0642\u062f \u0637\u064f\u0628\u0651\u0650\u0642\u064e \u0627\u062e\u062a\u0628\u0627\u0631 Kruskal-Wallis \u0645\u062a\u0628\u0648\u0639\u0627\u064b \u0628\u0627\u062e\u062a\u0628\u0627\u0631 Mann-Whitney\u060c \u0648\u0627\u0639\u062a\u0645\u062f\u062a \u0642\u064a\u0645\u0629 P<0.05 \u0643\u0642\u064a\u0645\u0629 \u064a\u064f\u0639\u062a\u062f\u0651\u064f \u0628\u0647\u0627 \u0625\u062d\u0635\u0627\u0626\u064a\u0627\u064b.<\/span><\/p>\n

\u0627\u0644\u0646\u062a\u0627\u0626\u062c<\/strong><\/span><\/p>\n

\u0627\u0644\u062e\u0635\u0627\u0626\u0635 \u0627\u0644\u0639\u0627\u0645\u0629 \u0648\u0627\u0644\u062f\u064a\u0645\u0648\u063a\u0631\u0627\u0641\u064a\u0629 \u0644\u0623\u0641\u0631\u0627\u062f \u0627\u0644\u062f\u0631\u0627\u0633\u0629<\/strong><\/span><\/p>\n

\u0634\u0645\u0644\u062a \u0639\u064a\u0646\u0629 \u0627\u0644\u062f\u0631\u0627\u0633\u0629 88 \u0641\u0631\u062f\u0627\u064b\u060c \u062c\u0631\u0649 \u062a\u0642\u0633\u064a\u0645\u0647\u0645 \u0648\u0641\u0642 4 \u0645\u062c\u0645\u0648\u0639\u0627\u062a. \u064a\u0638\u0647\u0631 )\u0627\u0644\u062c\u062f\u0648\u0644 1) \u0627\u0644\u0645\u062a\u0648\u0633\u0637 \u0627\u0644\u062d\u0633\u0627\u0628\u064a \u0648\u0627\u0644\u0627\u0646\u062d\u0631\u0627\u0641 \u0627\u0644\u0645\u0639\u064a\u0627\u0631\u064a \u0648\u0627\u0644\u0641\u0631\u0648\u0642 \u0627\u0644\u0625\u062d\u0635\u0627\u0626\u064a\u0629 \u0644\u0645\u062a\u063a\u064a\u0631\u0627\u062a \u0627\u0644\u062f\u064a\u0645\u0648\u063a\u0631\u0627\u0641\u064a\u0629 \u0648\u0627\u0644\u0643\u064a\u0645\u064a\u0627\u0626\u064a\u0629 \u0627\u0644\u062d\u064a\u0648\u064a\u0629 \u0644\u062f\u0649 \u0645\u062c\u0645\u0648\u0639\u0627\u062a \u0627\u0644\u062f\u0631\u0627\u0633\u0629. \u0628\u0644\u063a \u0627\u0644\u0645\u062a\u0648\u0633\u0637 \u0627\u0644\u062d\u0633\u0627\u0628\u064a \u00b1 \u0627\u0644\u0627\u0646\u062d\u0631\u0627\u0641 \u0627\u0644\u0645\u0639\u064a\u0627\u0631\u064a \u0644\u0644\u0639\u0645\u0631 \u0648\u0645\u062f\u0629 \u0627\u0644\u0625\u0635\u0627\u0628\u0629 \u0628\u0627\u0644\u0633\u0643\u0631\u064a \u0644\u062f\u0649 \u0645\u062c\u0645\u0648\u0639\u0629 \u0627\u0644\u0633\u0643\u0631\u064a\u064a\u0646 \u0627\u0644\u0628\u062f\u064a\u0646\u064a\u0646 (48.27\u00b17.82 \u0639\u0627\u0645\u0627\u064b) 2.92\u00b13.29) \u0639\u0627\u0645\u0627\u064b) \u0639\u0644\u0649 \u0627\u0644\u062a\u0648\u0627\u0644\u064a\u060c \u0648\u0644\u062f\u0649 \u0645\u062c\u0645\u0648\u0639\u0629 \u0627\u0644\u0633\u0643\u0631\u064a\u064a\u0646 \u0623\u0633\u0648\u064a\u0627\u0621 \u0627\u0644\u0648\u0632\u0646 (\u00b151.73 8.82 \u0639\u0627\u0645\u0627\u064b) 4.17\u00b15.48) \u0639\u0627\u0645\u0627\u064b) \u0639\u0644\u0649 \u0627\u0644\u062a\u0648\u0627\u0644\u064a. \u0628\u064a\u0646\u0645\u0627 \u0628\u0644\u063a \u0627\u0644\u0645\u062a\u0648\u0633\u0637 \u0627\u0644\u062d\u0633\u0627\u0628\u064a \u00b1 \u0627\u0644\u0627\u0646\u062d\u0631\u0627\u0641 \u0627\u0644\u0645\u0639\u064a\u0627\u0631\u064a \u0644\u0644\u0639\u0645\u0631 \u0644\u062f\u0649 \u0645\u062c\u0645\u0648\u0639\u0629 \u0627\u0644\u0628\u062f\u064a\u0646\u064a\u0646 (49.88\u00b17.62 \u0639\u0627\u0645\u0627\u064b) \u0648\u0644\u062f\u0649 \u0645\u062c\u0645\u0648\u0639\u0629 \u0623\u0633\u0648\u064a\u0627\u0621 \u0627\u0644\u0648\u0632\u0646 7.61\u00b146.20) \u0639\u0627\u0645\u0627\u064b) (\u0627\u0644\u062c\u062f\u0648\u0644 1)<\/strong>.<\/strong> \u0644\u0645 \u064a\u0643\u0646 \u0647\u0646\u0627\u0644\u0643 \u0641\u0631\u0642 \u062f\u0627\u0644\u0651\u064c \u0625\u062d\u0635\u0627\u0626\u064a\u0627\u064b \u0628\u0627\u0644\u0646\u0633\u0628\u0629 \u0644\u0644\u0639\u0645\u0631 \u0628\u064a\u0646 \u0645\u062c\u0645\u0648\u0639\u0627\u062a \u0627\u0644\u062f\u0631\u0627\u0633\u0629 \u0627\u0644\u0623\u0631\u0628\u0639\u0629 (P=0.153)\u060c \u0628\u064a\u0646\u0645\u0627 \u0644\u0648\u062d\u0638 \u0648\u062c\u0648\u062f \u0641\u0631\u0642 \u064a\u064f\u0639\u062a\u062f\u0651\u064f \u0628\u0647 \u0625\u062d\u0635\u0627\u0626\u064a\u0627\u064b \u0628\u0627\u0644\u0646\u0633\u0628\u0629 \u0644\u0645\u062f\u0629 \u0627\u0644\u0625\u0635\u0627\u0628\u0629 \u0628\u0627\u0644\u0633\u0643\u0631\u064a \u0628\u064a\u0646 \u0627\u0644\u0645\u062c\u0645\u0648\u0639\u062a\u064a\u0646 \u0627\u0644\u0645\u0631\u0636\u064a\u062a\u064a\u0646 (0.025P=). \u064a\u064f\u0648\u0636\u0651\u0650\u062d\u064f (\u0627\u0644\u0634\u0643\u0644 1) <\/strong>\u062a\u0648\u0632\u0651\u064f\u0639 \u0627\u0644\u0630\u0643\u0648\u0631 \u0648\u0627\u0644\u0625\u0646\u0627\u062b \u0644\u062f\u0649 \u0645\u062c\u0645\u0648\u0639\u0627\u062a \u0627\u0644\u062f\u0631\u0627\u0633\u0629.<\/span><\/p>\n

\u00a0 \u00a0 \u00a0 \u0627\u0644\u062c\u062f\u0648\u0644 (1): \u0627\u0644\u0645\u062a\u0648\u0633\u0637 \u0627\u0644\u062d\u0633\u0627\u0628\u064a \u0648\u0627\u0644\u0627\u0646\u062d\u0631\u0627\u0641 \u0627\u0644\u0645\u0639\u064a\u0627\u0631\u064a \u0648\u0627\u0644\u0641\u0631\u0648\u0642 \u0627\u0644\u0625\u062d\u0635\u0627\u0626\u064a\u0629 \u0644\u0645\u062a\u063a\u064a\u0631\u0627\u062a \u0627\u0644\u062f\u064a\u0645\u0648\u063a\u0631\u0627\u0641\u064a\u0629 \u0648\u0627\u0644\u0643\u064a\u0645\u064a\u0627\u0626\u064a\u0629 \u0627\u0644\u062d\u064a\u0648\u064a\u0629 \u0644\u062f\u0649 \u0645\u062c\u0645\u0648\u0639\u0627\u062a \u0627\u0644\u062f\u0631\u0627\u0633\u0629.<\/strong><\/span><\/p>\n\n\n\n\n\n\n\n\n\n\n
Variable<\/strong><\/span><\/td>\n\u0645\u062c\u0645\u0648\u0639\u0629 \u0627\u0644\u0633\u0643\u0631\u064a\u064a\u0646 \u0627\u0644\u0628\u062f\u064a\u0646\u064a\u0646<\/strong><\/span><\/p>\n

N=37 (42%)<\/strong><\/span><\/td>\n

\u0645\u062c\u0645\u0648\u0639\u0629 \u0627\u0644\u0633\u0643\u0631\u064a\u064a\u0646 \u0623\u0633\u0648\u064a\u0627\u0621 \u0627\u0644\u0648\u0632\u0646<\/strong><\/span><\/p>\n

N=33 (38%)<\/strong><\/span><\/td>\n

\u0645\u062c\u0645\u0648\u0639\u0629 \u0627\u0644\u0628\u062f\u064a\u0646\u064a\u0646<\/strong> N=8 (9%)<\/strong><\/span><\/td>\n\u0645\u062c\u0645\u0648\u0639\u0629 \u0623\u0633\u0648\u064a\u0627\u0621 \u0627\u0644\u0648\u0632\u0646 <\/strong>N=10 (11%)<\/strong><\/span><\/td>\nP-value<\/strong><\/span><\/td>\n<\/tr>\n
Mean\u00b1 Standard Deviation (SD)<\/strong> \u00a0<\/strong><\/span><\/td>\n<\/tr>\n
BMI<\/strong><\/span><\/p>\n

(kg\/m2<\/sup>)<\/strong><\/span><\/td>\n

33\u00b1<\/span><\/p>\n

2.52<\/span><\/td>\n

24.02\u00b1<\/span><\/p>\n

0.71<\/span><\/td>\n

33.33\u00b1<\/span><\/p>\n

1.70<\/span><\/td>\n

24.18\u00b1<\/span><\/p>\n

0.54<\/span><\/td>\n

<0.0001b<\/sup><\/span><\/td>\n<\/tr>\n
WC<\/strong><\/span><\/p>\n

(cm)<\/strong><\/span><\/td>\n

109.16\u00b1<\/span><\/p>\n

7.10<\/span><\/td>\n

94.15\u00b1<\/span><\/p>\n

6.70<\/span><\/td>\n

105.25\u00b1<\/span><\/p>\n

6.16<\/span><\/td>\n

88.3\u00b1<\/span><\/p>\n

3.34<\/span><\/td>\n

<0.0001b<\/sup><\/span><\/td>\n<\/tr>\n
Age <\/strong><\/span><\/p>\n

(year)<\/strong><\/span><\/td>\n

48.27\u00b1<\/span><\/p>\n

7.82<\/span><\/td>\n

51.73\u00b1<\/span><\/p>\n

8.82<\/span><\/td>\n

49.88\u00b1<\/span><\/p>\n

7.62<\/span><\/td>\n

46.20\u00b1<\/span><\/p>\n

7.61<\/span><\/td>\n

0.153b<\/sup><\/span><\/td>\n<\/tr>\n
Duration of T2DM (year) <\/strong><\/span><\/td>\n3.29\u00b1<\/span><\/p>\n

2.92<\/span><\/td>\n

5.48\u00b1<\/span><\/p>\n

4.17<\/span><\/td>\n

–<\/span><\/td>\n–<\/span><\/td>\n0.025c<\/sup><\/span><\/td>\n<\/tr>\n
Chemerin<\/strong><\/span><\/p>\n

(ng\/ml)<\/strong><\/span><\/td>\n

182.27\u00b1<\/span><\/p>\n

39.73<\/span><\/td>\n

156.81\u00b1<\/span><\/p>\n

28.23<\/span><\/td>\n

141.59\u00b1<\/span><\/p>\n

24.51<\/span><\/td>\n

95.87\u00b1<\/span><\/p>\n

27.28<\/span><\/td>\n

<0.0001a<\/sup><\/span><\/td>\n<\/tr>\n
*: P<0.05, a: One-Way ANOVA Test, b: Kruskal-Wallis Test, c: Mann-Whitney Test.<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n
\"\u0627\u0644\u0634\u0643\u0644
\u0627\u0644\u0634\u0643\u0644 (1): \u062a\u0648\u0632\u0651\u064f\u0639 \u0627\u0644\u0630\u0643\u0648\u0631 \u0648\u0627\u0644\u0625\u0646\u0627\u062b \u0644\u062f\u0649 \u0645\u062c\u0645\u0648\u0639\u0627\u062a \u0627\u0644\u062f\u0631\u0627\u0633\u0629<\/figcaption><\/figure>\n

\u0646\u062a\u0627\u0626\u062c \u0645\u0639\u0627\u064a\u0631\u0629 \u0627\u0644\u0643\u064a\u0645\u064a\u0631\u064a\u0646 \u0627\u0644\u0645\u0635\u0644\u064a \u0644\u062f\u0649 \u0643\u0627\u0645\u0644 \u0639\u064a\u0646\u0629 \u0627\u0644\u062f\u0631\u0627\u0633\u0629. <\/strong><\/span><\/p>\n

\u0643\u0627\u0646 \u0627\u0644\u0645\u062a\u0648\u0633\u0637 \u0627\u0644\u062d\u0633\u0627\u0628\u064a \u00b1 \u0627\u0644\u0627\u0646\u062d\u0631\u0627\u0641 \u0627\u0644\u0645\u0639\u064a\u0627\u0631\u064a \u0644\u0644\u0643\u064a\u0645\u064a\u0631\u064a\u0646 \u0627\u0644\u0645\u0635\u0644\u064a \u0644\u062f\u0649 \u0645\u062c\u0645\u0648\u0639\u0629 \u0627\u0644\u0633\u0643\u0631\u064a\u064a\u0646 \u0627\u0644\u0628\u062f\u064a\u0646\u064a\u0646 )182.27\u00b139.73(ng\/ml \u00a0\u0648\u0644\u062f\u0649 \u0645\u062c\u0645\u0648\u0639\u0629 \u0627\u0644\u0633\u0643\u0631\u064a\u064a\u0646 \u0623\u0633\u0648\u064a\u0627\u0621 \u0627\u0644\u0648\u0632\u0646 )156.81\u00b128.23ng\/ml )\u060c \u0628\u064a\u0646\u0645\u0627 \u0643\u0627\u0646 \u0644\u062f\u0649 \u0645\u062c\u0645\u0648\u0639\u0629 \u0627\u0644\u0628\u062f\u064a\u0646\u064a\u0646 )141.59\u00b124.51 (ng\/ml \u0648\u0644\u062f\u0649 \u0645\u062c\u0645\u0648\u0639\u0629 \u0623\u0633\u0648\u064a\u0627\u0621 \u0627\u0644\u0648\u0632\u0646 )95.87\u00b127.28 (ng\/ml \u00a0(\u0627\u0644\u062c\u062f\u0648\u0644 1)<\/strong>.<\/strong><\/span><\/p>\n

\u0645\u0642\u0627\u0631\u0646\u0629 \u0645\u0633\u062a\u0648\u064a\u0627\u062a \u0627\u0644\u0643\u064a\u0645\u064a\u0631\u064a\u0646 \u0627\u0644\u0645\u0635\u0644\u064a\u0651\u064e\u0629 \u0628\u064a\u0646 \u0627\u0644\u0645\u062c\u0645\u0648\u0639\u0627\u062a \u0627\u0644\u0645\u062f\u0631\u0648\u0633\u0629.<\/strong><\/span><\/p>\n

\u0643\u0627\u0646 \u0647\u0646\u0627\u0644\u0643 \u0641\u0631\u0642 \u064a\u064f\u0639\u062a\u062f\u0651\u064f \u0628\u0647 \u0625\u062d\u0635\u0627\u0626\u064a\u0627\u064b \u0641\u064a \u0645\u0633\u062a\u0648\u064a\u0627\u062a \u0627\u0644\u0643\u064a\u0645\u064a\u0631\u064a\u0646 \u0627\u0644\u0645\u0635\u0644\u064a\u0651\u064e\u0629 \u0628\u064a\u0646 \u0645\u062c\u0645\u0648\u0639\u0627\u062a \u0627\u0644\u062f\u0631\u0627\u0633\u0629 \u0627\u0644\u0623\u0631\u0628\u0639\u0629 (0.0001>P) (\u0627\u0644\u062c\u062f\u0648\u0644 1)<\/strong>. \u0644\u0648\u062d\u0638 \u0627\u0631\u062a\u0641\u0627\u0639 \u0645\u0639\u062a\u062f\u0651\u064c \u0628\u0647 \u0625\u062d\u0635\u0627\u0626\u064a\u0627\u064b \u0641\u064a \u0645\u0633\u062a\u0648\u064a\u0627\u062a \u0627\u0644\u0643\u064a\u0645\u064a\u0631\u064a\u0646 \u0627\u0644\u0645\u0635\u0644\u064a\u0651\u064e\u0629 \u0644\u062f\u0649 \u0645\u062c\u0645\u0648\u0639\u0629 \u0627\u0644\u0633\u0643\u0631\u064a\u064a\u0646 \u0627\u0644\u0628\u062f\u064a\u0646\u064a\u0646 \u0645\u0642\u0627\u0631\u0646\u0629\u064b \u0645\u0639 \u0645\u0633\u062a\u0648\u064a\u0627\u062a\u0647 \u0644\u062f\u0649 \u0645\u062c\u0645\u0648\u0639\u0629 \u0627\u0644\u0633\u0643\u0631\u064a\u064a\u0646 \u0623\u0633\u0648\u064a\u0627\u0621 \u0627\u0644\u0648\u0632\u0646 (P=0.022) \u0648\u0644\u062f\u0649 \u0645\u062c\u0645\u0648\u0639\u0629 \u0627\u0644\u0628\u062f\u064a\u0646\u064a\u0646 (P=0.025) \u0648\u0644\u062f\u0649 \u0645\u062c\u0645\u0648\u0639\u0629 \u0623\u0633\u0648\u064a\u0627\u0621 \u0627\u0644\u0648\u0632\u0646 P<0.0001)). \u0648\u062c\u062f \u0627\u0631\u062a\u0641\u0627\u0639 \u0645\u0639\u062a\u062f\u0651\u064c \u0628\u0647 \u0625\u062d\u0635\u0627\u0626\u064a\u0627\u064b \u0641\u064a \u0645\u0633\u062a\u0648\u064a\u0627\u062a \u0627\u0644\u0643\u064a\u0645\u064a\u0631\u064a\u0646 \u0627\u0644\u0645\u0635\u0644\u064a\u0651\u064e\u0629 \u0644\u062f\u0649 \u0645\u062c\u0645\u0648\u0639\u0629 \u0627\u0644\u0633\u0643\u0631\u064a\u064a\u0646 \u0623\u0633\u0648\u064a\u0627\u0621 \u0627\u0644\u0648\u0632\u0646 \u0645\u0642\u0627\u0631\u0646\u0629\u064b \u0645\u0639 \u0645\u0633\u062a\u0648\u064a\u0627\u062a\u0647 \u0644\u062f\u0649 \u0645\u062c\u0645\u0648\u0639\u0629 \u0623\u0633\u0648\u064a\u0627\u0621 \u0627\u0644\u0648\u0632\u0646 P<0.0001)) \u0648\u0644\u0645 \u064a\u0643\u0646 \u0647\u0646\u0627\u0644\u0643 \u0641\u0631\u0642 \u064a\u064f\u0639\u062a\u062f\u0651\u064f \u0628\u0647 \u0625\u062d\u0635\u0627\u0626\u064a\u0627\u064b \u0645\u0642\u0627\u0631\u0646\u0629\u064b \u0645\u0639 \u0645\u062c\u0645\u0648\u0639\u0629 \u0627\u0644\u0628\u062f\u064a\u0646\u064a\u0646 P=0.719)). \u0644\u0648\u062d\u0638 \u0627\u0631\u062a\u0641\u0627\u0639 \u0645\u0639\u062a\u062f\u0651\u064c \u0628\u0647 \u0641\u064a \u0645\u0633\u062a\u0648\u064a\u0627\u062a \u0627\u0644\u0643\u064a\u0645\u064a\u0631\u064a\u0646 \u0627\u0644\u0645\u0635\u0644\u064a\u0651\u064e\u0629 \u0644\u062f\u0649 \u0645\u062c\u0645\u0648\u0639\u0629 \u0627\u0644\u0628\u062f\u064a\u0646\u064a\u0646 \u0645\u0642\u0627\u0631\u0646\u0629 \u0645\u0639 \u0645\u062c\u0645\u0648\u0639\u0629 \u0623\u0633\u0648\u064a\u0627\u0621 \u0627\u0644\u0648\u0632\u0646 P=0.045)) (\u0627\u0644\u062c\u062f\u0648\u0644 2).<\/strong><\/span><\/p>\n

\u0627\u0644\u062c\u062f\u0648\u0644 (2): \u0627\u0644\u0641\u0631\u0648\u0642 \u0627\u0644\u062b\u0646\u0627\u0626\u064a\u0629 \u0628\u064a\u0646 \u0645\u062c\u0645\u0648\u0639\u0627\u062a \u0627\u0644\u062f\u0631\u0627\u0633\u0629 \u0644\u0645\u062a\u063a\u064a\u0631\u0627\u062a \u0627\u0644\u0645\u062f\u0631\u0648\u0633\u0629.<\/strong><\/span><\/p>\n\n\n\n\n\n\n\n\n\n\n
\u0627\u0644\u0645\u062c\u0645\u0648\u0639\u0627\u062a \u0627\u0644\u062b\u0646\u0627\u0626\u064a\u0629 \u0627\u0644\u0645\u0642\u0627\u0631\u0646\u0629<\/strong><\/span><\/td>\nChemerina<\/sup><\/strong><\/span><\/td>\nBMIb<\/sup><\/strong><\/span><\/td>\nWCb<\/sup><\/strong><\/span><\/td>\n<\/tr>\n
\u0645\u062c\u0645\u0648\u0639\u0629 \u0627\u0644\u0633\u0643\u0631\u064a\u064a\u0646 \u0627\u0644\u0628\u062f\u064a\u0646\u064a\u0646-\u0645\u062c\u0645\u0648\u0639\u0629 \u0627\u0644\u0633\u0643\u0631\u064a\u064a\u0646 \u0623\u0633\u0648\u064a\u0627\u0621 \u0627\u0644\u0648\u0632\u0646<\/strong><\/span><\/td>\n0.022*<\/sup><\/span><\/td>\n<0.0001*<\/sup><\/span><\/td>\n<0.0001*<\/sup><\/span><\/td>\n<\/tr>\n
\u0645\u062c\u0645\u0648\u0639\u0629 \u0627\u0644\u0633\u0643\u0631\u064a\u064a\u0646 \u0627\u0644\u0628\u062f\u064a\u0646\u064a\u0646-\u0645\u062c\u0645\u0648\u0639\u0629 \u0627\u0644\u0628\u062f\u064a\u0646\u064a\u0646<\/strong><\/span><\/td>\n0.025*<\/sup><\/span><\/td>\n0.449<\/span><\/td>\n0.191<\/span><\/td>\n<\/tr>\n
\u0645\u062c\u0645\u0648\u0639\u0629 \u0627\u0644\u0633\u0643\u0631\u064a\u064a\u0646 \u0627\u0644\u0628\u062f\u064a\u0646\u064a\u0646-\u0645\u062c\u0645\u0648\u0639\u0629 \u0623\u0633\u0648\u064a\u0627\u0621 \u0627\u0644\u0648\u0632\u0646<\/strong><\/span><\/td>\n<0.0001*<\/sup><\/span><\/td>\n<0.0001*<\/sup><\/span><\/td>\n<0.0001*<\/sup><\/span><\/td>\n<\/tr>\n
\u0645\u062c\u0645\u0648\u0639\u0629 \u0627\u0644\u0633\u0643\u0631\u064a\u064a\u0646 \u0623\u0633\u0648\u064a\u0627\u0621 \u0627\u0644\u0648\u0632\u0646-\u0645\u062c\u0645\u0648\u0639\u0629 \u0627\u0644\u0628\u062f\u064a\u0646\u064a\u0646<\/strong><\/span><\/td>\n0.719<\/span><\/td>\n<0.0001*<\/sup><\/span><\/td>\n0.001*<\/sup><\/span><\/td>\n<\/tr>\n
\u0645\u062c\u0645\u0648\u0639\u0629 \u0627\u0644\u0633\u0643\u0631\u064a\u064a\u0646 \u0623\u0633\u0648\u064a\u0627\u0621 \u0627\u0644\u0648\u0632\u0646-\u0645\u062c\u0645\u0648\u0639\u0629 \u0623\u0633\u0648\u064a\u0627\u0621 \u0627\u0644\u0648\u0632\u0646<\/strong><\/span><\/td>\n<0.0001*<\/sup><\/span><\/td>\n0.574<\/span><\/td>\n0.007*<\/sup><\/span><\/td>\n<\/tr>\n
\u0645\u062c\u0645\u0648\u0639\u0629 \u0627\u0644\u0628\u062f\u064a\u0646\u064a\u0646-\u0645\u062c\u0645\u0648\u0639\u0629 \u0623\u0633\u0648\u064a\u0627\u0621 \u0627\u0644\u0648\u0632\u0646<\/strong><\/span><\/td>\n0.045*<\/sup><\/span><\/td>\n<0.001*<\/sup><\/span><\/td>\n\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 <0.001*<\/sup><\/span><\/td>\n<\/tr>\n
*: P<0.05, a: Scheffe Test, b: Mann-Whitney Test.<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

 <\/p>\n

 <\/p>\n

 <\/p>\n

 <\/p>\n

\u0645\u0642\u0627\u0631\u0646\u0629 \u0642\u064a\u0645 \u0645\u0646\u0633\u0628 <\/strong>BMI<\/strong> \u0628\u064a\u0646 \u0627\u0644\u0645\u062c\u0645\u0648\u0639\u0627\u062a \u0627\u0644\u0645\u062f\u0631\u0648\u0633\u0629.<\/strong><\/span><\/p>\n

\u0643\u0627\u0646 \u0647\u0646\u0627\u0644\u0643 \u0641\u0631\u0642 \u064a\u064f\u0639\u062a\u062f\u0651\u064f \u0628\u0647 \u0625\u062d\u0635\u0627\u0626\u064a\u0627\u064b \u0641\u064a \u0642\u064a\u0645 \u0645\u0646\u0633\u0628 BMI \u0628\u064a\u0646 \u0645\u062c\u0645\u0648\u0639\u0627\u062a \u0627\u0644\u062f\u0631\u0627\u0633\u0629 \u0627\u0644\u062b\u0644\u0627\u062b (0.0001>P) (\u0627\u0644\u062c\u062f\u0648\u0644 <\/strong>1<\/strong>)<\/strong>. \u0644\u0648\u062d\u0638 \u0627\u0631\u062a\u0641\u0627\u0639 \u0645\u0639\u062a\u062f\u0651\u064c \u0628\u0647 \u0625\u062d\u0635\u0627\u0626\u064a\u0627\u064b \u0641\u064a \u0642\u064a\u0645 \u0645\u0646\u0633\u0628 BMI \u0644\u062f\u0649 \u0645\u062c\u0645\u0648\u0639\u0629 \u0627\u0644\u0633\u0643\u0631\u064a\u064a\u0646 \u0627\u0644\u0628\u062f\u064a\u0646\u064a\u0646 \u0645\u0642\u0627\u0631\u0646\u0629\u064b \u0645\u0639 \u0645\u062c\u0645\u0648\u0639\u0629 \u0627\u0644\u0633\u0643\u0631\u064a\u064a\u0646 \u0623\u0633\u0648\u064a\u0627\u0621 \u0627\u0644\u0648\u0632\u0646 (0.0001>(P \u0648\u0645\u062c\u0645\u0648\u0639\u0629 \u0623\u0633\u0648\u064a\u0627\u0621 \u0627\u0644\u0648\u0632\u0646 (0.0001>(P \u0648\u0639\u062f\u0645 \u0648\u062c\u0648\u062f \u0641\u0631\u0642 \u064a\u064f\u0639\u062a\u062f\u0651\u064f \u0628\u0647 \u0625\u062d\u0635\u0627\u0626\u064a\u0627\u064b \u0645\u0642\u0627\u0631\u0646\u0629 \u0645\u0639 \u0645\u062c\u0645\u0648\u0639\u0629 \u0627\u0644\u0628\u062f\u064a\u0646\u064a\u0646 P=0.449)). \u0648\u062c\u062f \u0627\u0646\u062e\u0641\u0627\u0636 \u064a\u064f\u0639\u062a\u062f\u0651\u064f \u0628\u0647 \u0625\u062d\u0635\u0627\u0626\u064a\u0627\u064b \u0641\u064a \u0642\u064a\u0645 \u0645\u0646\u0633\u0628 BMI \u0644\u062f\u0649 \u0645\u062c\u0645\u0648\u0639\u0629 \u0627\u0644\u0633\u0643\u0631\u064a\u064a\u0646 \u0623\u0633\u0648\u064a\u0627\u0621 \u0627\u0644\u0648\u0632\u0646 \u0645\u0642\u0627\u0631\u0646\u0629\u064b \u0645\u0639 \u0645\u062c\u0645\u0648\u0639\u0629 \u0627\u0644\u0628\u062f\u064a\u0646\u064a\u0646 (0.0001>(P \u0648\u0639\u062f\u0645 \u0648\u062c\u0648\u062f \u0641\u0631\u0642 \u064a\u064f\u0639\u062a\u062f\u0651\u064f \u0628\u0647 \u0625\u062d\u0635\u0627\u0626\u064a\u0627\u064b \u0645\u0642\u0627\u0631\u0646\u0629\u064b \u0645\u0639 \u0645\u062c\u0645\u0648\u0639\u0629 \u0623\u0633\u0648\u064a\u0627\u0621 \u0627\u0644\u0648\u0632\u0646 P=0.574)). \u0644\u0648\u062d\u0638 \u0627\u0631\u062a\u0641\u0627\u0639 \u0645\u0639\u062a\u062f\u0651\u064c \u0628\u0647 \u0641\u064a \u0642\u064a\u0645 \u0645\u0646\u0633\u0628 BMI \u0644\u062f\u0649 \u0645\u062c\u0645\u0648\u0639\u0629 \u0627\u0644\u0628\u062f\u064a\u0646\u064a\u0646 \u0645\u0642\u0627\u0631\u0646\u0629 \u0645\u0639 \u0645\u062c\u0645\u0648\u0639\u0629 \u0623\u0633\u0648\u064a\u0627\u0621 \u0627\u0644\u0648\u0632\u0646 P<0.001)) (\u0627\u0644\u062c\u062f\u0648\u0644 2)<\/strong>.<\/span><\/p>\n

\u0645\u0642\u0627\u0631\u0646\u0629 \u0642\u064a\u0645 <\/strong>WC<\/strong> \u0628\u064a\u0646 \u0627\u0644\u0645\u062c\u0645\u0648\u0639\u0627\u062a \u0627\u0644\u0645\u062f\u0631\u0648\u0633\u0629.<\/strong><\/span><\/p>\n

\u0643\u0627\u0646 \u0647\u0646\u0627\u0644\u0643 \u0641\u0631\u0642 \u064a\u064f\u0639\u062a\u062f\u064f\u0651 \u0628\u0647 \u0625\u062d\u0635\u0627\u0626\u064a\u0627\u064b \u0641\u064a \u0642\u064a\u0645 WC \u0628\u064a\u0646 \u0645\u062c\u0645\u0648\u0639\u0627\u062a \u0627\u0644\u062f\u0631\u0627\u0633\u0629 \u0627\u0644\u062b\u0644\u0627\u062b (0.0001>P) (\u0627\u0644\u062c\u062f\u0648\u0644 <\/strong>1<\/strong>)<\/strong>. \u0627\u0631\u062a\u0641\u0639\u062a \u0642\u064a\u0645 WC \u0628\u0634\u0643\u0644 \u0645\u0639\u062a\u062f\u0651\u064d \u0628\u0647 \u0625\u062d\u0635\u0627\u0626\u064a\u0627\u064b \u0644\u062f\u0649 \u0645\u062c\u0645\u0648\u0639\u0629 \u0627\u0644\u0633\u0643\u0631\u064a\u064a\u0646 \u0627\u0644\u0628\u062f\u064a\u0646\u064a\u0646 \u0645\u0642\u0627\u0631\u0646\u0629\u064b \u0645\u0639 \u0645\u062c\u0645\u0648\u0639\u0629 \u0627\u0644\u0633\u0643\u0631\u064a\u064a\u0646 \u0623\u0633\u0648\u064a\u0627\u0621 \u0627\u0644\u0648\u0632\u0646 (0.0001>(P \u0648\u0645\u062c\u0645\u0648\u0639\u0629 \u0623\u0633\u0648\u064a\u0627\u0621 \u0627\u0644\u0648\u0632\u0646 (0.0001>P) \u0648\u0644\u0645 \u0646\u062c\u062f \u0641\u0631\u0642\u0627\u064b \u064a\u064f\u0639\u062a\u062f\u0651\u064f \u0628\u0647 \u0625\u062d\u0635\u0627\u0626\u064a\u0627\u064b \u0645\u0642\u0627\u0631\u0646\u0629 \u0645\u0639 \u0645\u062c\u0645\u0648\u0639\u0629 \u0627\u0644\u0628\u062f\u064a\u0646\u064a\u0646 (P=0.191). \u0648\u062c\u062f \u0627\u0646\u062e\u0641\u0627\u0636 \u064a\u064f\u0639\u062a\u062f\u0651\u064f \u0628\u0647 \u0625\u062d\u0635\u0627\u0626\u064a\u0627\u064b \u0641\u064a \u0642\u064a\u0645 WC \u0644\u062f\u0649 \u0645\u062c\u0645\u0648\u0639\u0629 \u0627\u0644\u0633\u0643\u0631\u064a\u064a\u0646 \u0623\u0633\u0648\u064a\u0627\u0621 \u0627\u0644\u0648\u0632\u0646 \u0645\u0642\u0627\u0631\u0646\u0629\u064b \u0645\u0639 \u0645\u062c\u0645\u0648\u0639\u0629 \u0627\u0644\u0628\u062f\u064a\u0646\u064a\u0646 (0.001=P)\u060c \u0643\u0645\u0627 \u0643\u0627\u0646 \u0647\u0646\u0627\u0644\u0643 \u0627\u0631\u062a\u0641\u0627\u0639 \u064a\u064f\u0639\u062a\u062f\u0651\u064f \u0628\u0647 \u0625\u062d\u0635\u0627\u0626\u064a\u0627\u064b \u0641\u064a \u0642\u064a\u0645 WC \u0644\u062f\u0649 \u0645\u062c\u0645\u0648\u0639\u0629 \u0627\u0644\u0633\u0643\u0631\u064a\u064a\u0646 \u0623\u0633\u0648\u064a\u0627\u0621 \u0627\u0644\u0648\u0632\u0646 \u0645\u0642\u0627\u0631\u0646\u0629\u064b \u0645\u0639 \u0645\u062c\u0645\u0648\u0639\u0629 \u0623\u0633\u0648\u064a\u0627\u0621 \u0627\u0644\u0648\u0632\u0646 P=0.007)). \u0644\u0648\u062d\u0638 \u0627\u0631\u062a\u0641\u0627\u0639 \u0645\u0639\u062a\u062f\u0651\u064c \u0628\u0647 \u0641\u064a \u0642\u064a\u0645 WC \u0644\u062f\u0649 \u0645\u062c\u0645\u0648\u0639\u0629 \u0627\u0644\u0628\u062f\u064a\u0646\u064a\u0646 \u0645\u0642\u0627\u0631\u0646\u0629 \u0645\u0639 \u0645\u062c\u0645\u0648\u0639\u0629 \u0623\u0633\u0648\u064a\u0627\u0621 \u0627\u0644\u0648\u0632\u0646 P<0.001)) (\u0627\u0644\u062c\u062f\u0648\u0644 2)<\/strong>.<\/span><\/p>\n

\u062a\u0642\u064a\u064a\u0645 \u0639\u0644\u0627\u0642\u0629 \u0627\u0644\u0627\u0631\u062a\u0628\u0627\u0637 \u0628\u064a\u0646 \u0645\u0633\u062a\u0648\u064a\u0627\u062a \u0627\u0644\u0643\u064a\u0645\u064a\u0631\u064a\u0646 \u0627\u0644\u0645\u0635\u0644\u064a\u0651\u064e\u0629 \u0645\u0639 \u0642\u064a\u0645 <\/strong>WC<\/strong> \u0644\u062f\u0649 \u0645\u062c\u0645\u0648\u0639\u0629 \u0627\u0644\u0633\u0643\u0631\u064a\u064a\u0646 \u0627\u0644\u0628\u062f\u064a\u0646\u064a\u0646 \u0648\u0645\u062c\u0645\u0648\u0639\u0629 \u0627\u0644\u0633\u0643\u0631\u064a\u064a\u0646 \u0623\u0633\u0648\u064a\u0627\u0621 \u0627\u0644\u0648\u0632\u0646.<\/strong><\/span><\/p>\n

\u0627\u0631\u062a\u0628\u0637\u062a \u0645\u0633\u062a\u0648\u064a\u0627\u062a \u0627\u0644\u0643\u064a\u0645\u064a\u0631\u064a\u0646 \u0627\u0644\u0645\u0635\u0644\u064a\u0651\u064e\u0629 \u0628\u0634\u0643\u0644 \u0625\u064a\u062c\u0627\u0628\u064a \u0648\u0645\u0639\u062a\u062f\u0651\u064d \u0628\u0647 \u0625\u062d\u0635\u0627\u0626\u064a\u0627\u064b \u0645\u0639 \u0642\u064a\u0645 WC \u0644\u062f\u0649 \u0645\u062c\u0645\u0648\u0639\u0629 \u0627\u0644\u0633\u0643\u0631\u064a\u064a\u0646 \u0627\u0644\u0628\u062f\u064a\u0646\u064a\u0646\u060c (R=0.651, P<0.0001) (\u0627\u0644\u0634\u0643\u0644 2)<\/strong>\u060c \u0648\u0644\u062f\u0649 \u0645\u062c\u0645\u0648\u0639\u0629 \u0627\u0644\u0633\u0643\u0631\u064a\u064a\u0646 \u0623\u0633\u0648\u064a\u0627\u0621 \u0627\u0644\u0648\u0632\u0646 (R=0.358, P=0.041) (\u0627\u0644\u0634\u0643\u0644 3)<\/strong>.<\/span><\/p>\n

\"\"<\/p>\n

\u0627\u0644\u0645\u0646\u0627\u0642\u0634\u0629\u00a0<\/strong><\/span><\/p>\n

\u0642\u064f\u0645\u0646\u0627 \u0641\u064a \u0647\u0630\u0647 \u0627\u0644\u062f\u0631\u0627\u0633\u0629 \u0628\u062a\u0642\u064a\u064a\u0645 \u0645\u0633\u062a\u0648\u064a\u0627\u062a \u0627\u0644\u0643\u064a\u0645\u064a\u0631\u064a\u0646 \u0627\u0644\u0645\u0635\u0644\u064a\u0651\u064e\u0629 \u0644\u062f\u0649 \u0627\u0644\u0628\u062f\u064a\u0646\u064a\u0651\u0646 \u0648\u0623\u0633\u0648\u064a\u0627\u0621 \u0627\u0644\u0648\u0632\u0646 \u0645\u0646 \u0627\u0644\u0633\u0643\u0631\u064a\u064a\u0651\u0650\u0646 \u0645\u0646 \u0627\u0644\u0646\u0645\u0637 2 \u0648\u0627\u0633\u062a\u0642\u0635\u0627\u0621 \u0639\u0644\u0627\u0642\u0629 \u0647\u0630\u0647 \u0627\u0644\u0645\u0633\u062a\u0648\u064a\u0627\u062a \u0645\u0639 \u0642\u064a\u0645 \u0645\u064f\u062d\u064a\u0637 \u0627\u0644\u062e\u0635\u0631 \u0648\u0627\u0644\u0630\u064a \u064a\u064f\u0645\u062b\u0644 \u0627\u0644\u062f\u0651\u064f\u0647\u0648\u0646 \u0627\u0644\u062d\u0634\u0648\u064a\u0629\u060c \u0645\u0646 \u0623\u062c\u0644 \u0641\u0647\u0645 \u062f\u0648\u0631 \u0627\u0644\u0643\u064a\u0645\u064a\u0631\u064a\u0646 \u0641\u064a \u0647\u0630\u0627 \u0627\u0644\u0645\u0631\u0636 \u0628\u0634\u0643\u0644 \u0623\u0641\u0636\u0644 \u0628\u062a\u0648\u0633\u0637 \u0627\u0644\u0633\u0645\u0646\u0629 \u0627\u0644\u062d\u0634\u0648\u064a\u0629 \u0648\u0644\u0644\u062a\u062d\u0642\u0642 \u0645\u0646 \u0635\u062d\u0629 \u0641\u0631\u0636\u064a\u0629 \u0627\u0631\u062a\u0641\u0627\u0639 \u0645\u0633\u062a\u0648\u064a\u0627\u062a \u0627\u0644\u0643\u064a\u0645\u064a\u0631\u064a\u0646 \u0627\u0644\u0645\u0635\u0644\u064a\u0651\u064e\u0629 \u0644\u062f\u0649 \u0627\u0644\u0633\u0643\u0631\u064a\u064a\u0651\u0650\u0646 \u0645\u0646 \u0627\u0644\u0646\u0645\u0637 2 \u0633\u0648\u0627\u0621 \u0627\u0644\u0628\u062f\u064a\u0646\u064a\u0651\u0650\u0646 \u0623\u0648 \u0623\u0633\u0648\u064a\u0627\u0621 \u0627\u0644\u0648\u0632\u0646. <\/span>\u0623\u064e\u0638\u0647\u0631\u062a \u0646\u062a\u0627\u0626\u062c\u0646\u0627 \u0627\u0631\u062a\u0641\u0627\u0639\u0627\u064b \u0645\u0639\u062a\u062f\u0627\u064b \u0628\u0647 \u0625\u062d\u0635\u0627\u0626\u064a\u0627\u064b \u0641\u064a \u0645\u0633\u062a\u0648\u064a\u0627\u062a \u0627\u0644\u0643\u064a\u0645\u064a\u0631\u064a\u0646 \u0627\u0644\u0645\u0635\u0644\u064a\u0651\u064e\u0629 \u0644\u062f\u0649 \u0645\u062c\u0645\u0648\u0639\u0629 \u0627\u0644\u0628\u062f\u064a\u0646\u064a\u0651\u0650\u0646 \u0627\u0644\u0633\u0643\u0631\u064a\u064a\u0651\u0650\u0646 \u0645\u0642\u0627\u0631\u0646\u0629\u064b \u0645\u0639 \u0645\u062c\u0645\u0648\u0639\u0629 \u0627\u0644\u0633\u0643\u0631\u064a\u064a\u0651\u0646 \u0623\u0633\u0648\u064a\u0627\u0621 \u0627\u0644\u0648\u0632\u0646 \u0648\u0645\u0639 \u0645\u062c\u0645\u0648\u0639\u0629 \u0623\u0633\u0648\u064a\u0627\u0621 \u0627\u0644\u0648\u0632\u0646. \u0643\u0645\u0627 \u0644\u0648\u062d\u0638 \u0627\u0631\u062a\u0641\u0627\u0639 \u0645\u0639\u062a\u062f\u0651\u064c \u0628\u0647 \u0625\u062d\u0635\u0627\u0626\u064a\u0627\u064b \u0641\u064a \u0645\u0633\u062a\u0648\u064a\u0627\u062a \u0627\u0644\u0643\u064a\u0645\u064a\u0631\u064a\u0646 \u0627\u0644\u0645\u0635\u0644\u064a\u0651\u064e\u0629 \u0644\u062f\u0649 \u0645\u062c\u0645\u0648\u0639\u0629 \u0627\u0644\u0628\u062f\u064a\u0646\u064a\u0651\u0650\u0646 \u0645\u0642\u0627\u0631\u0646\u0629\u064b \u0645\u0639 \u0645\u062c\u0645\u0648\u0639\u0629 \u0623\u0633\u0648\u064a\u0627\u0621 \u0627\u0644\u0648\u0632\u0646. \u0642\u062f \u064a\u064f\u0641\u064e\u0633\u0651\u064e\u0631\u064f \u0630\u0644\u0643 \u0648\u0641\u0642 \u0645\u0627 \u0630\u0643\u0631\u062a\u0647 \u0627\u0644\u0623\u062f\u0628\u064a\u0627\u062a \u0627\u0644\u0633\u0627\u0628\u0642\u0629\u060c \u0644\u0643\u0648\u0646 \u0627\u0644\u0623\u0646\u0633\u062c\u0629 \u0627\u0644\u0634\u062d\u0645\u064a\u0629 \u0627\u0644\u0628\u064a\u0636\u0627\u0621 \u0627\u0644\u0645\u0635\u062f\u0631 \u0627\u0644\u0631\u0626\u064a\u0633\u064a \u0644\u0627\u0631\u062a\u0641\u0627\u0639 \u0645\u0633\u062a\u0648\u064a\u0627\u062a \u0627\u0644\u0643\u064a\u0645\u064a\u0631\u064a\u0646 \u0627\u0644\u0645\u0635\u0644\u064a\u0651\u064e\u0629 \u0648\u0627\u0645\u062a\u0644\u0627\u0643 \u0627\u0644\u0645\u062c\u0645\u0648\u0639\u0627\u062a \u0627\u0644\u0628\u062f\u064a\u0646\u0629 \u0644\u0643\u062a\u0644\u0629 \u0634\u062d\u0645\u064a\u0629 \u0623\u0643\u0628\u0631 \u0645\u0642\u0627\u0631\u0646\u0629 \u0645\u0639 \u0627\u0644\u0645\u062c\u0645\u0648\u0639\u0627\u062a \u0633\u0648\u064a\u0651\u064e\u0629 \u0627\u0644\u0648\u0632\u0646 (3, 16). \u0639\u064e\u0644\u0627\u0648\u0629\u064b \u0639\u0644\u0649 \u0630\u0644\u0643\u060c \u064a\u0648\u062c\u062f \u062a\u0623\u062b\u064a\u0631 \u0645\u062a\u0628\u0627\u062f\u0644 \u0628\u064a\u0646 \u0627\u0644\u0643\u064a\u0645\u064a\u0631\u064a\u0646 \u0648\u0627\u0644\u0633\u0645\u0646\u0629. \u0625\u0630 \u062a\u064e\u062a\u0645\u064a\u0632 \u0627\u0644\u0633\u0645\u0646\u0629 \u0628\u062d\u062f\u0648\u062b \u062a\u0648\u0633\u0639 \u0641\u064a \u0627\u0644\u0623\u0646\u0633\u062c\u0629 \u0627\u0644\u0634\u062d\u0645\u064a\u0629 \u0639\u0628\u0631 \u0641\u064e\u0631\u0637 \u062a\u0646\u0633\u062c \u0648\u062a\u064e\u0636\u062e\u0645 \u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u0634\u062d\u0645\u064a\u0629 (14) \u0648\u0647\u064f\u0645\u0627 \u0645\u0646 \u0627\u0644\u0639\u0645\u0644\u064a\u0627\u062a \u0627\u0644\u062a\u064a \u064a\u064f\u0639\u0632\u0632\u0647\u0627 \u0627\u0644\u0643\u064a\u0645\u064a\u0631\u064a\u0646 \u0648\u062a\u064e\u0632\u064a\u062f \u0645\u0646 \u0645\u0633\u062a\u0648\u064a\u0627\u062a\u0647 \u0627\u0644\u062f\u0645\u0648\u064a\u0629 (24) \u0639\u0628\u0631 \u062a\u064e\u062d\u0641\u064a\u0632 \u0627\u0644\u0643\u064a\u0645\u064a\u0631\u064a\u0646 \u0644\u0644\u0639\u062f\u064a\u062f \u0645\u0646 \u0645\u064e\u0633\u0627\u0631\u0627\u062a \u0627\u0644\u0625\u0634\u0627\u0631\u0629 \u0628\u0645\u0627 \u0641\u064a\u0647\u0627 Mitogen Activated Protein Kinase Extracellular Signal, Regulated Kinase 1\/2 (MAPK, ERK 1\/2)\u060c \u0648\u0641\u0642 \u0645\u0627 \u0630\u0643\u0631\u0647 \u00a0(14, 15, 25, 26). \u0643\u0645\u0627 \u064a\u064f\u0624\u062b\u0631 \u0627\u0644\u0643\u064a\u0645\u064a\u0631\u064a\u0646 \u0641\u064a \u0623\u064e\u0646\u0645\u0627\u0637 \u062e\u0644\u0648\u064a\u0651\u064e\u0629 \u0645\u062a\u0646\u0648\u0639\u0629 \u0628\u0645\u0627 \u0641\u064a\u0647\u0627 \u0637\u064e\u0644\u0627\u0626\u0639 \u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u0634\u062d\u0645\u064a\u0629 Preadipocytes \u0648\u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u062c\u0630\u0639\u064a\u0651\u064e\u0629 \u0627\u0644\u0648\u0633\u064a\u0637\u0629 \u0627\u0644\u0646\u0642\u0648\u064a\u0629 Bone Marrow Mesenchymal Stem Cells (BMSCs) \u0648\u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u0639\u0636\u0644\u064a\u0651\u064e\u0629 Myoblast cells \u0648\u064a\u0648\u062c\u0647 \u062a\u0645\u0627\u064a\u0632\u0647\u0627 \u0646\u062d\u0648 \u0627\u0644\u062a\u0643\u0648\u064f\u0651\u0646 \u0627\u0644\u0634\u062d\u0645\u064a\u0651\u0650\u060c \u0645\u0645\u0627 \u064a\u064e\u0646\u062a\u062c \u0639\u0646\u0647 \u0632\u064a\u0627\u062f\u0629 \u0641\u064a \u0639\u062f\u062f \u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u0634\u062d\u0645\u064a\u0629 \u0627\u0644\u0646\u0627\u0636\u062c\u0629 \u0648\u0627\u0644\u062a\u064a \u062a\u0632\u064a\u062f \u0628\u062f\u0648\u0631\u0647\u0627 \u0645\u0646 \u0625\u0646\u062a\u0627\u062c \u0627\u0644\u0643\u064a\u0645\u064a\u0631\u064a\u0646 \u0648\u0645\u0633\u062a\u0648\u064a\u0627\u062a\u0647 \u0627\u0644\u062f\u0645\u0648\u064a\u0629 (15, 25). \u0645\u0645\u0627 \u064a\u064f\u062b\u0628\u062a \u0648\u062c\u0648\u062f \u062a\u0623\u062b\u064a\u0631 \u0645\u062a\u0628\u0627\u062f\u0644 \u0628\u064a\u0646 \u0627\u0644\u0643\u064a\u0645\u064a\u0631\u064a\u0646 \u0648\u0627\u0644\u0633\u0645\u0646\u0629 \u0648\u064a\u064f\u0624\u0643\u0651\u0650\u062f \u0646\u062a\u0627\u0626\u062c \u0647\u0630\u0647 \u0627\u0644\u062f\u0631\u0627\u0633\u0629\u060c \u062d\u064a\u062b \u0627\u0650\u0645\u062a\u0644\u0643\u062a \u0645\u062c\u0645\u0648\u0639\u062a\u0627 \u0627\u0644\u0633\u0643\u0631\u064a\u064a\u0646 \u0627\u0644\u0628\u062f\u064a\u0646\u064a\u0646 \u0648\u0627\u0644\u0628\u062f\u064a\u0646\u064a\u0646 \u0643\u062a\u0644\u0629 \u0634\u062d\u0645\u064a\u0629 \u0645\u062a\u0648\u0633\u0639\u0629 \u0648\u0632\u064a\u0627\u062f\u0629 \u0641\u064a \u062a\u062c\u0645\u0639 \u0627\u0644\u062f\u0651\u064f\u0647\u0648\u0646 \u0636\u0645\u0646 \u0627\u0644\u0645\u0646\u0637\u0642\u0629 \u0627\u0644\u062d\u0634\u0648\u064a\u0629 \u0646\u0638\u0631\u0627\u064b \u0644\u0627\u0631\u062a\u0641\u0627\u0639 \u0642\u064a\u0645 BMI \u0648WC \u0645\u0642\u0627\u0631\u0646\u0629 \u0645\u0639 \u0645\u062c\u0645\u0648\u0639\u062a\u064a \u0627\u0644\u0633\u0643\u0631\u064a\u064a\u0646 \u0623\u0633\u0648\u064a\u0627\u0621 \u0627\u0644\u0648\u0632\u0646 \u0648\u0623\u0633\u0648\u064a\u0627\u0621 \u0627\u0644\u0648\u0632\u0646 (\u0627\u0644\u062c\u062f\u0648\u0644 2)<\/strong>\u060c \u0627\u0644\u0623\u0645\u0631 \u0627\u0644\u0630\u064a \u064a\u064e\u062a\u0633\u0628\u0628 \u0641\u064a \u0632\u064a\u0627\u062f\u0629 \u0625\u0650\u0646\u062a\u0627\u062c \u0627\u0644\u0643\u064a\u0645\u064a\u0631\u064a\u0646 \u0648\u0645\u064f\u0633\u062a\u0648\u064a\u0627\u062a\u0647 \u0627\u0644\u0645\u0635\u0644\u064a\u0651\u064e\u0629. \u0643\u0627\u0646\u062a \u0647\u0630\u0647 \u0627\u0644\u0646\u062a\u0627\u0626\u062c \u0645\u062a\u0641\u0642\u0629 \u0645\u0639 \u0645\u0627 \u062a\u0648\u0635\u0644\u062a \u0625\u0644\u064a\u0647 \u062f\u0631\u0627\u0633\u0629 \u0627\u0644\u0634\u0627\u0641\u0639\u064a \u0648\u0622\u062e\u0631\u064a\u0646\u060c 2019 \u0641\u064a \u0645\u0635\u0631 (23)\u060c \u0648\u062f\u0631\u0627\u0633\u0629 \u0645\u064a\u0631 \u0648\u0622\u062e\u0631\u064a\u0646\u060c 2022 \u0641\u064a \u0627\u0644\u0633\u0639\u0648\u062f\u064a\u0629 (12)\u060c \u0648\u0627\u0644\u0630\u064a\u0646 \u0648\u062c\u062f\u0648\u0627 \u0627\u0631\u062a\u0641\u0627\u0639\u0627\u064b \u0645\u064f\u0639\u062a\u062f\u0627\u064b \u0628\u0647 \u0625\u062d\u0635\u0627\u0626\u064a\u0627\u064b \u0641\u064a \u0645\u0633\u062a\u0648\u064a\u0627\u062a \u0627\u0644\u0643\u064a\u0645\u064a\u0631\u064a\u0646 \u0627\u0644\u0645\u0635\u0644\u064a\u0651\u064e\u0629 \u0644\u062f\u0649 \u0645\u062c\u0645\u0648\u0639\u0629 \u0627\u0644\u0633\u0643\u0631\u064a\u064a\u0651\u0650\u0646 \u0627\u0644\u0628\u062f\u064a\u0646\u064a\u0651\u0650\u0646 \u0645\u0642\u0627\u0631\u0646\u0629\u064b \u0645\u0639 \u0645\u062c\u0645\u0648\u0639\u0629 \u0623\u0633\u0648\u064a\u0627\u0621 \u0627\u0644\u0648\u0632\u0646. \u0643\u0645\u0627 \u0627\u0650\u062a\u0641\u0642\u062a \u0646\u062a\u0627\u0626\u062c\u0646\u0627 \u0645\u0639 \u0646\u062a\u064a\u062c\u0629 \u062f\u0631\u0627\u0633\u0629 \u0633\u064a\u0646 \u0648\u0622\u062e\u0631\u064a\u0646\u060c 2019 \u0641\u064a \u0627\u0644\u0647\u0646\u062f (27)\u060c \u0648\u0627\u0644\u0630\u064a\u0646 \u0648\u062c\u062f\u0648\u0627 \u0627\u0631\u062a\u0641\u0627\u0639\u0627\u064b \u0645\u064f\u0639\u062a\u062f\u0651\u064e\u0627\u064b \u0628\u0647 \u0625\u062d\u0635\u0627\u0626\u064a\u0627\u064b \u0641\u064a \u0645\u0633\u062a\u0648\u064a\u0627\u062a \u0627\u0644\u0643\u064a\u0645\u064a\u0631\u064a\u0646 \u0627\u0644\u0645\u0635\u0644\u064a\u0651\u064e\u0629 \u0644\u062f\u0649 \u0645\u062c\u0645\u0648\u0639\u0629 \u0627\u0644\u0633\u0643\u0631\u064a\u064a\u0651\u0650\u0646 \u0627\u0644\u0628\u062f\u064a\u0646\u064a\u0651\u0650\u0646 \u0645\u0642\u0627\u0631\u0646\u0629\u064b \u0645\u0639 \u0645\u062c\u0645\u0648\u0639\u0629 \u0627\u0644\u0633\u0643\u0631\u064a\u064a\u0651\u0650\u0646 \u0623\u0633\u0648\u064a\u0627\u0621 \u0627\u0644\u0648\u0632\u0646. \u0643\u0645\u0627 \u062a\u064e\u0648\u0627\u0641\u0642\u062a \u0647\u0630\u0647 \u0627\u0644\u0646\u062a\u064a\u062c\u0629 \u0645\u0639 \u0646\u062a\u064a\u062c\u0629 \u0625\u062d\u062f\u0649 \u0627\u0644\u062f\u0631\u0627\u0633\u0627\u062a\u060c 2021 \u0641\u064a \u0645\u0635\u0631 (22)\u060c \u0648\u0627\u0644\u0630\u064a\u0646 \u0648\u062c\u062f\u0648\u0627 \u0627\u0631\u062a\u0641\u0627\u0639\u0627\u064b \u0645\u064f\u0639\u062a\u062f\u0651\u064e\u0627\u064b \u0628\u0647 \u0625\u062d\u0635\u0627\u0626\u064a\u0627\u064b \u0641\u064a \u0645\u0633\u062a\u0648\u064a\u0627\u062a \u0627\u0644\u0643\u064a\u0645\u064a\u0631\u064a\u0646 \u0627\u0644\u0645\u0635\u0644\u064a\u0651\u064e\u0629 \u0644\u062f\u0649 \u0645\u062c\u0645\u0648\u0639\u0629 \u0627\u0644\u0628\u062f\u064a\u0646\u064a\u0651\u0650\u0646 \u0645\u0642\u0627\u0631\u0646\u0629\u064b \u0645\u0639 \u0645\u062c\u0645\u0648\u0639\u0629 \u0623\u0633\u0648\u064a\u0627\u0621 \u0627\u0644\u0648\u0632\u0646. <\/span>\u0623\u064a\u0636\u0627\u064b\u060c \u0648\u064f\u062c\u062f\u0646\u0627 \u0627\u0631\u062a\u0641\u0627\u0639\u0627\u064b \u0645\u064f\u0639\u062a\u062f\u0627\u064b \u0628\u0647 \u0625\u062d\u0635\u0627\u0626\u064a\u0627\u064b \u0641\u064a \u0645\u0633\u062a\u0648\u064a\u0627\u062a \u0627\u0644\u0643\u064a\u0645\u064a\u0631\u064a\u0646 \u0627\u0644\u0645\u0635\u0644\u064a\u0651\u064e\u0629 \u0644\u062f\u0649 \u0645\u062c\u0645\u0648\u0639\u0629 \u0627\u0644\u0633\u0643\u0631\u064a\u064a\u0651\u0650\u0646 \u0627\u0644\u0628\u062f\u064a\u0646\u064a\u0651\u0650\u0646 \u0645\u0642\u0627\u0631\u0646\u0629\u064b \u0645\u0639 \u0645\u062c\u0645\u0648\u0639\u0629 \u0627\u0644\u0628\u062f\u064a\u0646\u064a\u0651\u0650\u0646\u060c \u064a\u064f\u0645\u0643\u0646 \u062a\u0641\u0633\u064a\u0631 \u0630\u0644\u0643 \u0628\u0633\u0628\u0628 \u0642\u0650\u062f\u0631\u0629 \u0627\u0644\u0623\u0646\u0633\u062c\u0629 \u0627\u0644\u0634\u062d\u0645\u064a\u0629 \u0644\u062f\u0649 \u0627\u0644\u0633\u0643\u0631\u064a\u064a\u0651\u0650\u0646 \u0639\u0644\u0649 \u0625\u0646\u062a\u0627\u062c \u0648\u062a\u062d\u0631\u064a\u0631 \u0643\u0645\u064a\u0629 \u0623\u0643\u0628\u0631 \u0645\u0646 \u0627\u0644\u0643\u064a\u0645\u064a\u0631\u064a\u0646 \u0645\u0642\u0627\u0631\u0646\u0629\u064b \u0645\u0639 \u0627\u0644\u0628\u062f\u064a\u0646\u064a\u0651\u0646 \u0627\u0644\u0645\u0637\u0627\u0628\u0642\u064a\u0646 \u0645\u0646 \u062d\u064a\u062b BMI\u060c \u0645\u0645\u0627 \u064a\u0632\u064a\u062f \u0645\u0646 \u0645\u0633\u062a\u0648\u064a\u0627\u062a \u0627\u0644\u0643\u064a\u0645\u064a\u0631\u064a\u0646 \u0627\u0644\u0645\u0635\u0644\u064a\u0651\u064e\u0629 \u0644\u062f\u0649 \u0647\u0624\u0644\u0627\u0621 \u0627\u0644\u0645\u0631\u0636\u0649 (28). \u0648\u0642\u062f \u0648\u064f\u062c\u062f\u062a \u0646\u062a\u064a\u062c\u0629 \u0645\u0645\u0627\u062b\u0644\u0629 \u0644\u0644\u0646\u062a\u064a\u062c\u0629 \u0627\u0644\u0633\u0627\u0628\u0642\u0629 \u0641\u064a \u062f\u0631\u0627\u0633\u0629 \u0639\u0628\u062f \u0627\u0644\u062d\u0645\u064a\u062f \u0648\u0622\u062e\u0631\u064a\u0646\u060c 2019 \u0641\u064a \u0645\u0635\u0631 (29). <\/span>\u0643\u0645\u0627 \u0623\u064e\u0634\u0627\u0631\u062a \u062f\u0631\u0627\u0633\u062a\u0646\u0627 \u0627\u0644\u062d\u0627\u0644\u064a\u0629 \u0625\u0644\u0649 \u0648\u064f\u062c\u0648\u062f \u0627\u0631\u062a\u0641\u0627\u0639 \u0645\u064f\u0639\u062a\u062f\u0651\u064d \u0628\u0647 \u0625\u062d\u0635\u0627\u0626\u064a\u0627\u064b \u0641\u064a \u0645\u0633\u062a\u0648\u064a\u0627\u062a \u0627\u0644\u0643\u064a\u0645\u064a\u0631\u064a\u0646 \u0627\u0644\u0645\u0635\u0644\u064a\u0651\u064e\u0629 \u0644\u062f\u0649 \u0645\u062c\u0645\u0648\u0639\u0629 \u0627\u0644\u0633\u0643\u0631\u064a\u064a\u0651\u0650\u0646 \u0623\u0633\u0648\u064a\u0627\u0621 \u0627\u0644\u0648\u0632\u0646 \u0639\u0646\u062f \u0627\u0644\u0645\u0642\u0627\u0631\u0646\u0629 \u0645\u0639 \u0645\u062c\u0645\u0648\u0639\u0629 \u0623\u0633\u0648\u064a\u0627\u0621 \u0627\u0644\u0648\u0632\u0646. \u0642\u062f \u064a\u064f\u0639\u0632\u0649 \u0630\u0644\u0643 \u0648\u0641\u0642 \u0645\u0627 \u0630\u0643\u0631\u062a\u0647 \u0627\u0644\u0623\u062f\u0628\u064a\u0627\u062a \u0627\u0644\u0633\u0627\u0628\u0642\u0629 \u0625\u0644\u0649 \u0645\u064f\u0639\u0627\u0646\u0627\u0629 \u0623\u063a\u0644\u0628 \u0627\u0644\u0633\u0643\u0631\u064a\u064a\u0651\u0650\u0646 \u0623\u0633\u0648\u064a\u0627\u0621 \u0627\u0644\u0648\u0632\u0646 \u0645\u0646 \u0632\u064a\u0627\u062f\u0629 \u0641\u064a \u0627\u0644\u0623\u0646\u0633\u062c\u0629 \u0627\u0644\u0634\u062d\u0645\u064a\u0629 \u0627\u0644\u0628\u064a\u0636\u0627\u0621 \u0627\u0644\u062d\u0634\u0648\u064a\u0629 \u0648\u0627\u0644\u062a\u064a \u062a\u064e\u0632\u064a\u062f \u0628\u062f\u0648\u0631\u0647\u0627 \u0645\u0646 \u0625\u0650\u0641\u0631\u0627\u0632 \u0627\u0644\u0643\u064a\u0645\u064a\u0631\u064a\u0646 \u0627\u0644\u0634\u062d\u0645\u064a \u0644\u062f\u0649 \u0627\u0644\u0633\u0643\u0631\u064a\u064a\u0651\u0650\u0646 \u0623\u0633\u0648\u064a\u0627\u0621 \u0627\u0644\u0648\u0632\u0646 (11, 30)\u060c \u0645\u0645\u0627 \u064a\u0631\u0641\u0639 \u0645\u0646 \u0645\u0633\u062a\u0648\u064a\u0627\u062a \u0627\u0644\u0643\u064a\u0645\u064a\u0631\u064a\u0646 \u0627\u0644\u0645\u0635\u0644\u064a\u0651\u064e\u0629 \u0644\u062f\u0649 \u0647\u0624\u0644\u0627\u0621 \u0627\u0644\u0645\u0631\u0636\u0649. \u0648\u0642\u062f \u0623\u0638\u0647\u0631\u062a \u0646\u062a\u0627\u0626\u062c \u0647\u0630\u0647 \u0627\u0644\u062f\u0631\u0627\u0633\u0629 \u0627\u0650\u0645\u062a\u0644\u0627\u0643 \u0645\u062c\u0645\u0648\u0639\u0629 \u0627\u0644\u0633\u0643\u0631\u064a\u064a\u0646 \u0623\u0633\u0648\u064a\u0627\u0621 \u0627\u0644\u0648\u0632\u0646 \u0644\u0643\u062a\u0644\u0629 \u062d\u0634\u0648\u064a\u0629 \u0623\u0643\u0628\u0631 (\u0646\u0638\u0631\u0627\u064b \u0644\u0627\u0631\u062a\u0641\u0627\u0639 \u0642\u064a\u0645 WC) \u0645\u0642\u0627\u0631\u0646\u0629\u064b \u0645\u0639 \u0645\u062c\u0645\u0648\u0639\u0629 \u0623\u0633\u0648\u064a\u0627\u0621 \u0627\u0644\u0648\u0632\u0646\u060c \u0645\u0645\u0627 \u0642\u062f \u064a\u0632\u064a\u062f \u0645\u0646 \u0625\u0641\u0631\u0627\u0632 \u0627\u0644\u0643\u064a\u0645\u064a\u0631\u064a\u0646 \u0648\u0645\u0646 \u062b\u0645\u0651\u064e \u064a\u0631\u0641\u0639 \u0645\u0646 \u0645\u0633\u062a\u0648\u064a\u0627\u062a\u0647 \u0627\u0644\u0645\u0635\u0644\u064a\u0651\u064e\u0629. \u0643\u0627\u0646\u062a \u0647\u0630\u0647 \u0627\u0644\u0646\u062a\u064a\u062c\u0629 \u0645\u064f\u062a\u0648\u0627\u0641\u0642\u0629 \u0645\u0639 \u062f\u0650\u0631\u0627\u0633\u0629 \u0627\u0644\u0634\u0627\u0641\u0639\u064a \u0648\u0622\u062e\u0631\u064a\u0646\u060c 2016 \u0641\u064a \u0645\u0635\u0631(23) \u060c \u0648\u0645\u064f\u062a\u062e\u0627\u0644\u0641\u0629 \u0645\u0639 \u062f\u0650\u0631\u0627\u0633\u0629 \u0645\u064a\u0631 \u0648\u0622\u062e\u0631\u064a\u0646\u060c 2022 \u0641\u064a \u0627\u0644\u0633\u0639\u0648\u062f\u064a\u0629 (12) \u0648\u0642\u062f \u064a\u064f\u0641\u064e\u0633\u0651\u064e\u0631\u064f \u0630\u0644\u0643 \u0628\u0633\u0628\u0628 \u0635\u063a\u0631 \u062d\u062c\u0645 \u0645\u062c\u0645\u0648\u0639\u0629 \u0627\u0644\u0633\u0643\u0631\u064a\u064a\u0651\u0650\u0646 \u0644\u062f\u0649 \u062f\u0631\u0627\u0633\u0629 \u0645\u064a\u0631 n=12 \u0648\u0648\u062c\u0648\u062f \u0643\u062a\u0644\u0629 \u0634\u062d\u0645\u064a\u0629 \u062d\u0634\u0648\u064a\u0629 \u0645\u062a\u0634\u0627\u0628\u0647\u0629 \u0644\u062f\u0649 \u0645\u062c\u0645\u0648\u0639\u062a\u064a \u0627\u0644\u0633\u0643\u0631\u064a\u064a\u0651\u0650\u0646 \u0623\u0633\u0648\u064a\u0627\u0621 \u0627\u0644\u0648\u0632\u0646 \u0648\u0623\u0633\u0648\u064a\u0627\u0621 \u0627\u0644\u0648\u0632\u0646 \u0644\u062f\u0649 \u062f\u0631\u0627\u0633\u062a\u0647\u0645. <\/span>\u0643\u0645\u0627 \u0623\u064e\u062b\u0628\u062a\u062a \u062f\u0631\u0627\u0633\u062a\u0646\u0627 \u0648\u062c\u0648\u062f \u0639\u0644\u0627\u0642\u0629 \u0627\u0631\u062a\u0628\u0627\u0637 \u064a\u064f\u0639\u062a\u062f\u0651\u064f \u0628\u0647\u0627 \u0625\u062d\u0635\u0627\u0626\u064a\u0627\u064b \u0628\u064a\u0646 \u0645\u0633\u062a\u0648\u064a\u0627\u062a \u0627\u0644\u0643\u064a\u0645\u064a\u0631\u064a\u0646 \u0627\u0644\u0645\u0635\u0644\u064a\u0651\u064e\u0629 \u0648\u0642\u064a\u0645 \u0645\u062d\u064a\u0637 \u0627\u0644\u062e\u0635\u0631 \u0644\u062f\u0649 \u0645\u062c\u0645\u0648\u0639\u0629 \u0627\u0644\u0633\u0643\u0631\u064a\u064a\u0651\u0650\u0646 \u0627\u0644\u0628\u062f\u064a\u0646\u064a\u0651\u0650\u0646 \u0648\u0645\u062c\u0645\u0648\u0639\u0629 \u0627\u0644\u0633\u0643\u0631\u064a\u064a\u0651\u0650\u0646 \u0623\u0633\u0648\u064a\u0627\u0621 \u0627\u0644\u0648\u0632\u0646. \u0642\u062f \u064a\u064f\u0641\u064e\u0633\u0651\u064e\u0631\u064f \u0627\u0631\u062a\u0628\u0627\u0637 \u0645\u0633\u062a\u0648\u064a\u0627\u062a \u0627\u0644\u0643\u064a\u0645\u064a\u0631\u064a\u0646 \u0645\u0639 \u0642\u0650\u064a\u0645 \u0645\u062d\u064a\u0637 \u0627\u0644\u062e\u0635\u0631 \u0644\u062f\u0649 \u0627\u0644\u0633\u0643\u0631\u064a\u064a\u0651\u0650\u0646 \u0627\u0644\u0628\u062f\u064a\u0646\u064a\u0651\u0650\u0646 \u0628\u0648\u062c\u0648\u062f \u062a\u064e\u0623\u062b\u064a\u0631 \u0645\u062a\u0628\u0627\u062f\u0644 \u0628\u064a\u0646 \u062a\u062d\u0631\u0631 \u0627\u0644\u0643\u064a\u0645\u064a\u0631\u064a\u0646 \u0648\u0627\u0644\u062a\u0647\u0627\u0628 \u0648\u062a\u064e\u0648\u0633\u0639 \u0627\u0644\u0623\u0646\u0633\u062c\u0629 \u0627\u0644\u0634\u062d\u0645\u064a\u0629 \u0627\u0644\u062d\u0634\u0648\u064a\u0629 \u0641\u064a \u062d\u0627\u0644\u0629 \u0627\u0644\u0633\u0645\u0646\u0629 \u0648\u0627\u0644\u062a\u064a \u062a\u0645\u062b\u0644 \u0627\u0644\u0645\u064e\u0635\u062f\u0631 \u0627\u0644\u0623\u0633\u0627\u0633\u064a \u0644\u0627\u0631\u062a\u0641\u0627\u0639 \u0627\u0644\u0643\u064a\u0645\u064a\u0631\u064a\u0646 \u0627\u0644\u0645\u0635\u0644\u064a \u0644\u062f\u0649 \u0627\u0644\u0633\u0643\u0631\u064a\u064a\u0651\u0650\u0646. \u0625\u0630 \u064a\u064e\u062d\u062b \u0627\u0644\u0643\u064a\u0645\u064a\u0631\u064a\u0646 \u0639\u0644\u0649 \u062c\u0630\u0628 \u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u0645\u0646\u0627\u0639\u064a\u0629 \u0627\u0644\u0627\u0644\u062a\u0647\u0627\u0628\u064a\u0651\u064e\u0629 \u0628\u0645\u0627 \u0641\u064a\u0647\u0627 \u0628\u0644\u0627\u0639\u0645 \u0645\u0646 \u0627\u0644\u0646\u0645\u0637 M1 (Macrophage M1) (8, 14, 31) \u0627\u0644\u0645\u064e\u0639\u0631\u0648\u0641\u0629 \u0628\u0642\u064f\u062f\u0631\u062a\u0647\u0627 \u0639\u0644\u0649 \u062a\u064e\u062d\u0631\u064a\u0631 \u0627\u0644\u0639\u062f\u064a\u062f \u0645\u0646 \u0627\u0644\u0633\u064a\u062a\u0648\u0643\u064a\u0646\u0627\u062a \u0627\u0644\u0627\u0644\u062a\u0647\u0627\u0628\u064a\u0651\u064e\u0629 \u0627\u0644\u0645\u062d\u0631\u0651\u0650\u0636\u0629\u064e \u0644\u0645\u064f\u0642\u0627\u0648\u0645\u0629 \u0627\u0644\u0623\u0646\u0633\u0648\u0644\u064a\u0646 \u0648\u0627\u0644\u0633\u0643\u0631\u064a (31). \u0643\u0645\u0627 \u064a\u064f\u0639\u0632\u0632 \u0627\u0644\u0643\u064a\u0645\u064a\u0631\u064a\u0646 \u0628\u0634\u0643\u0644 \u0645\u0628\u0627\u0634\u0631 \u0645\u0646 \u062a\u062d\u0631\u064f\u0651\u0631 \u0628\u0639\u0636 \u0627\u0644\u0633\u064a\u062a\u0648\u0643\u064a\u0646\u0627\u062a \u0627\u0644\u0627\u0644\u062a\u0647\u0627\u0628\u064a\u0651\u0629 \u0648\u0627\u0644\u0645\u064f\u0633\u0628\u0628\u0629 \u0644\u0645\u064f\u0642\u0627\u0648\u0645\u0629 \u0627\u0644\u0623\u0646\u0633\u0648\u0644\u064a\u0646 \u0648\u0627\u0644\u0633\u0643\u0631\u064a \u0644\u062f\u0649 \u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u0634\u062d\u0645\u064a\u0651\u0629 \u0628\u0645\u0627 \u0641\u064a\u0647\u0627 TNF-\u03b1)) \u0648\u0627\u0644\u0630\u064a \u064a\u0632\u064a\u062f \u0644\u0627\u062d\u0642\u0627\u064b \u0645\u0646 \u062a\u0646\u0634\u064a\u0637 \u0627\u0644\u0643\u064a\u0645\u064a\u0631\u064a\u0646 (10, 14, 18). \u0627\u0644\u0623\u0645\u0631 \u0627\u0644\u0630\u064a \u064a\u064f\u0624\u0643\u0651\u0650\u062f \u0639\u0644\u0649 \u0623\u0646\u0651\u064e \u0627\u0644\u0643\u064a\u0645\u064a\u0631\u064a\u0646 \u0623\u064e\u062f\u064a\u0628\u0648\u0643\u064a\u0646 \u062d\u0634\u0648\u064a \u0645\u064f\u0631\u062a\u0628\u0637 \u0628\u062e\u064e\u0644\u0644 \u0627\u0644\u0623\u0646\u0633\u062c\u0629 \u0627\u0644\u0634\u062d\u0645\u064a\u0629 \u0644\u062f\u0649 \u0627\u0644\u0633\u0643\u0631\u064a\u064a\u0651\u0650\u0646 \u0627\u0644\u0628\u062f\u064a\u0646\u064a\u0651\u0650\u0646. \u0648\u0642\u062f \u0643\u0627\u0646\u062a \u0642\u064a\u0645 \u0645\u062d\u064a\u0637 \u0627\u0644\u062e\u0635\u0631 \u0644\u062f\u0649 \u0645\u062c\u0645\u0648\u0639\u0629 \u0627\u0644\u0633\u0643\u0631\u064a\u064a\u0651\u0650\u0646 \u0627\u0644\u0628\u062f\u064a\u0646\u064a\u0651\u0650\u0646 \u0641\u064a \u0647\u0630\u0647 \u0627\u0644\u062f\u0631\u0627\u0633\u0629 \u0623\u0639\u0644\u0649 \u0645\u0642\u0627\u0631\u0646\u0629\u064b \u0645\u0639 \u0645\u062c\u0645\u0648\u0639\u0629 \u0623\u0633\u0648\u064a\u0627\u0621 \u0627\u0644\u0648\u0632\u0646\u060c \u0645\u0645\u0627 \u0642\u062f \u064a\u064e\u0632\u064a\u062f \u0645\u0646 \u0625\u0650\u0641\u0631\u0627\u0632 \u0627\u0644\u0643\u064a\u0645\u064a\u0631\u064a\u0646 \u0648\u0645\u0646 \u062b\u0645\u0651\u064e \u0645\u0646 \u0645\u0633\u062a\u0648\u064a\u0627\u062a\u0647 \u0627\u0644\u0645\u0635\u0644\u064a\u0651\u064e\u0629. \u0643\u0627\u0646\u062a \u0647\u0630\u0647 \u0627\u0644\u0646\u062a\u0627\u0626\u062c \u0645\u062a\u0648\u0627\u0641\u0642\u0629 \u0645\u0639 \u0646\u062a\u0627\u0626\u062c \u062f\u0631\u0627\u0633\u0629 \u0644\u0627\u0643\u0634\u0645\u064a \u0648\u0622\u062e\u0631\u064a\u0646\u060c 2022 \u0641\u064a \u0627\u0644\u0647\u0646\u062f\u00a0 (32). <\/span>\u0625\u0644\u0649 \u062c\u0627\u0646\u0628 \u0630\u0644\u0643\u060c \u0642\u062f \u064a\u064f\u0639\u0632\u0649 \u0627\u0631\u062a\u0628\u0627\u0637 \u0645\u0633\u062a\u0648\u064a\u0627\u062a \u0627\u0644\u0643\u064a\u0645\u064a\u0631\u064a\u0646 \u0645\u0639 \u0642\u0650\u064a\u064e\u0645 \u0645\u062d\u064a\u0637 \u0627\u0644\u062e\u0635\u0631 \u0644\u062f\u0649 \u0627\u0644\u0633\u0643\u0631\u064a\u064a\u0650\u0646 \u0648\u0641\u0642 \u0645\u0627 \u0630\u0643\u0631\u062a\u0647 \u0627\u0644\u0623\u062f\u0628\u064a\u0627\u062a \u0627\u0644\u0633\u0627\u0628\u0642\u0629 \u0625\u0644\u0649 \u0627\u0645\u062a\u0644\u0627\u0643 \u0627\u0644\u0633\u0643\u0631\u064a\u064a\u0651\u0650\u0646 \u0623\u0633\u0648\u064a\u0627\u0621 \u0627\u0644\u0648\u0632\u0646 \u0627\u0633\u062a\u0639\u062f\u0627\u062f\u0627\u064b \u0623\u0643\u0628\u0631 \u0644\u062a\u0631\u0633\u0628 \u0627\u0644\u062f\u0651\u064f\u0647\u0648\u0646 \u0636\u0645\u0646 \u0627\u0644\u0645\u0646\u0637\u0642\u0629 \u0627\u0644\u062d\u0634\u0648\u064a\u0651\u064e\u0629 (33) \u0648\u0627\u0631\u062a\u0628\u0627\u0637 \u0627\u0644\u0633\u0643\u0631\u064a \u0645\u0646 \u0627\u0644\u0646\u0645\u0637 2 \u0645\u0639 \u0627\u0644\u0623\u0646\u0633\u062c\u0629 \u0627\u0644\u0634\u062d\u0645\u064a\u0629 \u0627\u0644\u062d\u0634\u0648\u064a\u0651\u064e\u0629 \u0628\u062f\u0644\u0627\u064b \u0645\u0646 \u0627\u0644\u0633\u0645\u0646\u0629 \u0627\u0644\u0643\u064f\u0644\u064a\u0651\u064e\u0629 (34) \u0648\u0627\u0644\u062a\u064a \u062a\u064f\u0639\u062f\u0651\u064f \u0645\u064e\u0635\u062f\u0631\u0627\u064b \u0631\u0626\u064a\u0633\u064a\u0627\u064b \u0644\u0627\u0631\u062a\u0641\u0627\u0639 \u0627\u0644\u0645\u0633\u062a\u0648\u064a\u0627\u062a \u0627\u0644\u0645\u0635\u0644\u064a\u0651\u064e\u0629 \u0644\u0644\u0643\u064a\u0645\u064a\u0631\u064a\u0646 (5)\u060c \u062d\u064a\u062b \u064a\u064f\u0641\u0631\u0632 \u0627\u0644\u0643\u064a\u0645\u064a\u0631\u064a\u0646 \u0628\u0645\u0633\u062a\u0648\u064a\u0627\u062a \u0645\u0631\u062a\u0641\u0639\u0629 \u0645\u0646 \u0627\u0644\u0623\u0646\u0633\u062c\u0629 \u0627\u0644\u0634\u062d\u0645\u064a\u0629 \u0627\u0644\u062d\u0634\u0648\u064a\u0629 \u0644\u062f\u0649 \u0647\u0624\u0644\u0627\u0621 \u0627\u0644\u0645\u0631\u0636\u0649 \u0627\u0644\u0623\u0645\u0631 \u0627\u0644\u0630\u064a \u064a\u0632\u064a\u062f \u0645\u0646 \u0645\u064f\u0633\u062a\u0648\u064a\u0627\u062a\u0647 \u0627\u0644\u0645\u0635\u0644\u064a\u0651\u064e\u0629 (19, 35). \u0645\u0645\u0627 \u064a\u064f\u0641\u0633\u0651\u0650\u0631\u064f \u0627\u0644\u0646\u062a\u0627\u0626\u062c \u0627\u0644\u062a\u064a \u062d\u0635\u0644\u0646\u0627 \u0639\u0644\u064a\u0647\u0627\u060c \u062d\u064a\u062b \u0627\u0650\u0645\u062a\u0644\u0643\u062a \u0645\u062c\u0645\u0648\u0639\u0629 \u0627\u0644\u0633\u0643\u0631\u064a\u064a\u0651\u0650\u0646 \u0623\u0633\u0648\u064a\u0627\u0621 \u0627\u0644\u0648\u0632\u0646 \u0645\u062d\u064a\u0637 \u062e\u0635\u0631 \u0623\u0639\u0644\u0649 \u0645\u0642\u0627\u0631\u0646\u0629\u064b \u0645\u0639 \u0645\u062c\u0645\u0648\u0639\u0629 \u0623\u0633\u0648\u064a\u0627\u0621 \u0627\u0644\u0648\u0632\u0646\u00a0 (P=0.007)\u060c \u0643\u0627\u0646\u062a \u0647\u0630\u0647 \u0627\u0644\u0646\u062a\u0627\u0626\u062c \u0645\u062a\u0648\u0627\u0641\u0642\u0629 \u0645\u0639 \u062f\u0631\u0627\u0633\u0629 \u0647\u0627\u0646 \u0648\u0622\u062e\u0631\u064a\u0646 \u0641\u064a \u0643\u0648\u0631\u064a\u0627 (30).<\/span><\/p>\n

\u0627\u0644\u0627\u0633\u062a\u0646\u062a\u0627\u062c\u0627\u062a\u00a0<\/strong><\/span><\/p>\n

\u0623\u0638\u0647\u0631\u062a \u0646\u062a\u0627\u0626\u062c \u0647\u0630\u0647 \u0627\u0644\u062f\u0631\u0627\u0633\u0629 \u0627\u0631\u062a\u0641\u0627\u0639\u0627\u064b \u0645\u0639\u062a\u062f\u0627\u064b \u0628\u0647 \u0625\u062d\u0635\u0627\u0626\u064a\u0627\u064b \u0641\u064a \u0645\u0633\u062a\u0648\u064a\u0627\u062a \u0627\u0644\u0643\u064a\u0645\u064a\u0631\u064a\u0646 \u0627\u0644\u0645\u0635\u0644\u064a\u0651\u064e\u0629 \u0644\u062f\u0649 \u0627\u0644\u0633\u0643\u0631\u064a\u064a\u0651\u0650\u0646 \u0645\u0646 \u0627\u0644\u0646\u0645\u0637 2 \u0645\u0642\u0627\u0631\u0646\u0629\u064b \u0645\u0639 \u0627\u0644\u0623\u0635\u062d\u0627\u0621 \u0648\u062a\u0631\u0627\u0641\u0642\u062a \u0645\u0633\u062a\u0648\u064a\u0627\u062a\u0647 \u0627\u0644\u0623\u0634\u062f \u0627\u0631\u062a\u0641\u0627\u0639\u0627\u064b \u0645\u0639 \u0627\u0644\u0628\u062f\u064a\u0646\u064a\u0651\u0650\u0646 \u0627\u0644\u0633\u0643\u0631\u064a\u064a\u0651\u0650\u0646\u060c \u0643\u0645\u0627 \u0627\u0631\u062a\u0628\u0637\u062a \u0645\u0633\u062a\u0648\u064a\u0651\u0627\u062a \u0627\u0644\u0643\u064a\u0645\u064a\u0631\u064a\u0646 \u0627\u0644\u0645\u0635\u0644\u064a\u0651\u064e\u0629 \u0645\u0639 \u0642\u064a\u0645 \u0645\u062d\u064a\u0637 \u0627\u0644\u062e\u0635\u0631 \u0644\u062f\u0649 \u0643\u0644\u0627 \u0627\u0644\u0645\u062c\u0645\u0648\u0639\u062a\u064a\u0646 \u0627\u0644\u0645\u064e\u0631\u0636\u064a\u062a\u064a\u0646. \u0645\u0645\u0651\u0627 \u064a\u064f\u0624\u0643\u0651\u0650\u062f\u064f \u0639\u0644\u0649 \u0623\u0646\u0651\u064e \u0627\u0644\u0643\u064a\u0645\u064a\u0631\u064a\u0646 \u0623\u064e\u062f\u064a\u0628\u0648\u0643\u064a\u0646 \u0645\u064f\u0641\u0631\u0632 \u0645\u0646 \u0627\u0644\u0623\u0646\u0633\u062c\u0629 \u0627\u0644\u0634\u062d\u0645\u064a\u0629 \u0627\u0644\u062d\u0634\u0648\u064a\u0651\u064e\u0629 \u0627\u0644\u0645\u062a\u0636\u062e\u0645\u0651\u0650\u0629 \u0644\u062f\u0649 \u0627\u0644\u0633\u0643\u0631\u064a\u064a\u0651\u0650\u0646 \u0645\u0646 \u0627\u0644\u0646\u0645\u0637 2 \u0648\u0623\u0646\u0651\u064e \u0627\u0644\u0643\u064a\u0645\u064a\u0631\u064a\u0646 \u0645\u0646 \u0627\u0644\u0628\u0631\u0648\u062a\u064a\u0646\u0627\u062a \u0630\u0627\u062a \u0627\u0644\u0625\u0641\u0631\u0627\u0632 \u0627\u0644\u0645\u062a\u063a\u064a\u0631 \u0648\u0627\u0644\u0645\u0624\u0647\u0628\u0629 \u0644\u062a\u0637\u0648\u0631 \u0627\u0644\u0633\u0643\u0631\u064a \u0645\u0646 \u0627\u0644\u0646\u0645\u0637 2.<\/span><\/p>\n

\n","protected":false},"excerpt":{"rendered":"

\u0627\u0644\u0645\u0642\u062f\u0645\u0629 \u064a\u064f\u0639\u0651\u062f\u064f \u0627\u0644\u0633\u0643\u0631\u064a \u0645\u0646 \u0627\u0644\u0646\u0645\u0637 2 (Type 2 Diabetes Mellitus T2DM) \u0623\u064e\u062d\u062f \u0627\u0644\u0623\u0645\u0631\u0627\u0636 \u0627\u0644\u0627\u0633\u062a\u0642\u0644\u0627\u0628\u064a\u0629 \u0627\u0644\u0645\u064f\u0632\u0645\u0646\u0629 \u0627\u0644\u0645\u062a\u0632\u0627\u064a\u062f\u0629 \u0639\u0627\u0644\u0645\u064a\u0627\u064b\u060c \u0648\u0627\u0644\u062a\u064a \u062a\u064e\u062a\u0635\u0641 \u0628\u0627\u0631\u062a\u0641\u0627\u0639 \u0645\u0633\u062a\u0648\u064a\u0627\u062a \u063a\u0644\u0648\u0643\u0648\u0632…
\u0627\u0642\u0631\u0623 \u0627\u0644\u0645\u0632\u064a\u062f<\/a><\/p>\n","protected":false},"author":2,"featured_media":1608,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[136],"tags":[],"class_list":["post-1607","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-136","issue-154","volume-9","year-149"],"acf":[],"_links":{"self":[{"href":"https:\/\/pharmjournal.asscph.com\/index.php?rest_route=\/wp\/v2\/posts\/1607","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/pharmjournal.asscph.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/pharmjournal.asscph.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/pharmjournal.asscph.com\/index.php?rest_route=\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/pharmjournal.asscph.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=1607"}],"version-history":[{"count":0,"href":"https:\/\/pharmjournal.asscph.com\/index.php?rest_route=\/wp\/v2\/posts\/1607\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/pharmjournal.asscph.com\/index.php?rest_route=\/wp\/v2\/media\/1608"}],"wp:attachment":[{"href":"https:\/\/pharmjournal.asscph.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=1607"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/pharmjournal.asscph.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=1607"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/pharmjournal.asscph.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=1607"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}