{"id":180,"date":"2022-04-01T16:50:37","date_gmt":"2022-04-01T16:50:37","guid":{"rendered":"https:\/\/pharmjournal.asscph.com\/?p=180"},"modified":"2024-07-21T17:52:21","modified_gmt":"2024-07-21T17:52:21","slug":"%d9%86%d8%b3%d8%a8%d8%a9-%d8%a7%d9%84%d8%b1%d9%8a%d8%b2%d9%8a%d8%b3%d8%aa%d9%8a%d9%86-%d8%a5%d9%84%d9%89-%d8%a7%d9%84%d8%a3%d8%af%d9%8a%d8%a8%d9%88%d9%86%d9%8a%d9%83%d8%aa%d9%8a%d9%86-%d8%a8%d9%88","status":"publish","type":"post","link":"https:\/\/pharmjournal.asscph.com\/?p=180","title":{"rendered":"\u0646\u0633\u0628\u0629 \u0627\u0644\u0631\u064a\u0632\u064a\u0633\u062a\u064a\u0646 \u0625\u0644\u0649 \u0627\u0644\u0623\u062f\u064a\u0628\u0648\u0646\u064a\u0643\u062a\u064a\u0646 \u0628\u0648\u0635\u0641 \u0639\u0627\u0645\u0644\u0627\u064b \u062a\u0646\u0628\u0624\u064a\u0627\u064b \u0628\u0645\u0642\u0627\u0648\u0645\u0629 \u0627\u0644\u0623\u0646\u0633\u0648\u0644\u064a\u0646 \u0648\u0639\u0648\u0627\u0645\u0644 \u0627\u0644\u0627\u062e\u062a\u0637\u0627\u0631 \u0627\u0644\u0642\u0644\u0628\u064a\u0629 \u0627\u0644\u0648\u0639\u0627\u0626\u064a\u0629 \u0627\u0644\u0627\u0633\u062a\u0642\u0644\u0627\u0628\u064a\u0629 \u0648\u0627\u0644\u0627\u0644\u062a\u0647\u0627\u0628\u064a\u0629 \u0639\u0646\u062f \u0639\u064a\u0646\u0629 \u0645\u0646 \u0627\u0644\u0633\u0648\u0631\u064a\u064a\u0646 \u0627\u0644\u0645\u0635\u0627\u0628\u064a\u0646 \u0628\u0627\u0644\u0646\u0645\u0637 \u0627\u0644\u062b\u0627\u0646\u064a \u0645\u0646 \u0627\u0644\u062f\u0627\u0621 \u0627\u0644\u0633\u0643\u0631\u064a"},"content":{"rendered":"<p style=\"text-align: justify;\"><strong><span style=\"font-family: 'times new roman', times, serif;\">\u0627\u0644\u0645\u0642\u062f\u0645\u0629 Introduction:<\/span><\/strong><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-family: 'times new roman', times, serif;\">\u0627\u0644\u0623\u0645\u0631\u0627\u0636 \u0627\u0644\u0642\u0644\u0628\u064a\u0629 \u0627\u0644\u0648\u0639\u0627\u0626\u064a\u0629 \u0647\u064a \u0627\u0644\u0633\u0628\u0628 \u0627\u0644\u0623\u0648\u0644 \u0644\u0644\u0648\u0641\u064a\u0627\u062a \u0639\u0627\u0644\u0645\u064a\u0627\u064b\u060c \u0648\u0647\u064a \u0627\u0644\u0645\u0633\u0624\u0648\u0644\u0629 \u0639\u0646 \u062b\u0644\u062b \u0627\u0644\u0648\u0641\u064a\u0627\u062a \u0627\u0644\u0639\u0627\u0644\u0645\u064a\u0629 \u062a\u0642\u0631\u064a\u0628\u0627\u064b.<sup>[1-3]<\/sup> \u0648\u0627\u0644\u0623\u0643\u062b\u0631 \u0627\u0646\u062a\u0634\u0627\u0631\u0627\u064b \u0628\u064a\u0646 \u0647\u0630\u0647 \u0627\u0644\u0623\u0645\u0631\u0627\u0636 \u0647\u0648 \u0645\u0631\u0636 \u0627\u0644\u0642\u0644\u0628 \u0627\u0644\u0625\u0642\u0641\u0627\u0631\u064a ischemic heart disease IHD\u060c \u0648\u0627\u0644\u0630\u064a \u064a\u062f\u0639\u0649 \u0623\u064a\u0636\u0627\u064b \u062f\u0627\u0621 \u0627\u0644\u0642\u0644\u0628 \u0627\u0644\u062a\u0627\u062c\u064a coronary artery disease CAD \u0648\u0627\u0644\u062f\u0627\u0621 \u0627\u0644\u0642\u0644\u0628\u064a \u0627\u0644\u0648\u0639\u0627\u0626\u064a \u0627\u0644\u0639\u0635\u064a\u062f\u064a atherosclerotic cardiovascular disease ACD\u060c \u0648\u0647\u0648 \u0623\u0648\u0644 \u0627\u0644\u0623\u0633\u0628\u0627\u0628 \u0627\u0644\u0645\u0641\u0631\u062f\u0629 \u0644\u0644\u0648\u0641\u064a\u0627\u062a \u0648\u0641\u0642\u062f\u0627\u0646 \u0633\u0646\u0648\u0627\u062a \u0627\u0644\u0639\u0645\u0631 \u0627\u0644\u0645\u0635\u062d\u062d\u0629 \u0648\u0641\u0642 \u0627\u0644\u0625\u0639\u0627\u0642\u0629 \u0641\u064a \u0627\u0644\u0639\u0627\u0644\u0645. \u0648\u062a\u0639\u0648\u062f \u0632\u064a\u0627\u062f\u0629 \u0647\u0630\u0647 \u0627\u0644\u0623\u0645\u0631\u0627\u0636 \u0639\u0627\u0644\u0645\u064a\u0627\u064b \u0625\u0644\u0649 \u0627\u0644\u0632\u064a\u0627\u062f\u0629 \u0627\u0644\u0639\u0627\u0644\u0645\u064a\u0629 \u0641\u064a \u0643\u0644 \u0645\u0646 \u0645\u0639\u062f\u0644\u0627\u062a \u0627\u0644\u062a\u0634\u064a\u0651\u062e \u0648\u0639\u0648\u0627\u0645\u0644 \u0627\u0644\u0627\u062e\u062a\u0637\u0627\u0631 \u0627\u0644\u0642\u0644\u0628\u064a\u0629 \u0627\u0644\u0648\u0639\u0627\u0626\u064a\u0629 \u0627\u0644\u0645\u062e\u062a\u0644\u0641\u0629.<sup>[2-4]<\/sup> \u0648\u0627\u0644\u0639\u0645\u0644\u064a\u0629 \u0627\u0644\u0625\u0645\u0631\u0627\u0636\u064a\u0629 \u0627\u0644\u0631\u0626\u064a\u0633\u0629 \u0641\u064a \u0645\u0631\u0636 \u0627\u0644\u0642\u0644\u0628 \u0627\u0644\u0625\u0642\u0641\u0627\u0631\u064a \u0647\u064a \u0627\u0644\u062a\u0635\u0644\u0628 \u0627\u0644\u0639\u0635\u064a\u062f\u064a\u060c \u0648\u0647\u064a \u0639\u0628\u0627\u0631\u0629 \u0639\u0646 \u062d\u062f\u062b\u064a\u0629 \u0627\u0644\u062a\u0647\u0627\u0628\u064a\u0629 \u0634\u0631\u064a\u0627\u0646\u064a\u0629 \u062a\u062a\u0631\u0627\u0641\u0642 \u0645\u0639 \u062a\u0631\u0633\u0628 \u0627\u0644\u0634\u062d\u0645\u064a\u0627\u062a \u0648\u0627\u0644\u062a\u0628\u062f\u0644\u0627\u062a \u0627\u0644\u0627\u0633\u062a\u0642\u0644\u0627\u0628\u064a\u0629 \u0627\u0644\u0646\u0627\u062c\u0645\u0629 \u0639\u0646 \u0639\u0648\u0627\u0645\u0644 \u0627\u0644\u0627\u062e\u062a\u0637\u0627\u0631 \u0627\u0644\u0642\u0644\u0628\u064a\u0629 \u0627\u0644\u0648\u0639\u0627\u0626\u064a\u0629 \u0627\u0644\u0645\u062e\u062a\u0644\u0641\u0629 \u0648\u0627\u0644\u062a\u064a \u062a\u0634\u0645\u0644 \u0628\u0634\u0643\u0644 \u0631\u0626\u064a\u0633 \u0627\u0644\u063a\u0630\u0627\u0621 \u063a\u064a\u0631 \u0627\u0644\u0635\u062d\u064a \u0648\u0646\u0642\u0635 \u0627\u0644\u0646\u0634\u0627\u0637 \u0627\u0644\u0628\u062f\u0646\u064a \u0648\u0627\u0636\u0637\u0631\u0627\u0628 \u0634\u062d\u0645\u064a\u0627\u062a \u0627\u0644\u062f\u0645 \u0648\u0641\u0631\u0637 \u0633\u0643\u0631 \u0627\u0644\u062f\u0645 \u0648\u0627\u0631\u062a\u0641\u0627\u0639 \u0636\u063a\u0637 \u0627\u0644\u062f\u0645 \u0648\u0627\u0644\u0628\u062f\u0627\u0646\u0629 \u0648\u0627\u0644\u0639\u0645\u0631 \u0648\u063a\u064a\u0631\u0647\u0627.<sup>[1-7] <\/sup><\/span><span style=\"font-family: 'times new roman', times, serif;\">\u0627\u0644\u062f\u0627\u0621 \u0627\u0644\u0633\u0643\u0631\u064a \u0648\u0627\u062d\u062f\u064c \u0645\u0646 \u0623\u0633\u0631\u0639 \u0627\u0644\u062d\u0627\u0644\u0627\u062a \u0627\u0644\u0637\u0627\u0631\u0626\u0629 \u0627\u0644\u0635\u062d\u064a\u0629 \u0627\u0644\u0639\u0627\u0644\u0645\u064a\u0629 \u0627\u0646\u062a\u0634\u0627\u0631\u0627\u064b \u0641\u064a \u0627\u0644\u0642\u0631\u0646 \u0627\u0644\u062d\u0627\u062f\u064a \u0648\u0627\u0644\u0639\u0634\u0631\u064a\u0646\u060c \u0648\u0642\u062f \u0628\u0644\u063a \u0639\u062f\u062f \u0627\u0644\u0645\u0635\u0627\u0628\u064a\u0646 \u0628\u0647 \u0641\u064a \u0627\u0644\u0639\u0627\u0645 2019 \u0641\u064a \u0633\u0648\u0631\u064a\u0627 \u0646\u062d\u0648 1.2 \u0645\u0644\u064a\u0648\u0646 (\u0628\u0645\u0639\u062f\u0644 \u0627\u0646\u062a\u0634\u0627\u0631 \u0646\u062d\u0648 12.3%)\u060c \u0648\u0645\u0646 \u0627\u0644\u0645\u064f\u0642\u062f\u0651\u064e\u0631 \u0623\u0646 \u064a\u0635\u0644 \u0639\u062f\u062f \u0627\u0644\u0645\u0635\u0627\u0628\u064a\u0646 \u0628\u0647 \u0641\u064a \u0627\u0644\u0639\u0627\u0644\u0645 \u0639\u0627\u0645 2045 \u0625\u0644\u0649 700 \u0645\u0644\u064a\u0648\u0646. \u0648\u0642\u062f \u0628\u0644\u063a \u0639\u062f\u062f \u0627\u0644\u0648\u0641\u064a\u0627\u062a \u0644\u0623\u0633\u0628\u0627\u0628 \u062a\u062a\u0639\u0644\u0642 \u0628\u0627\u0644\u062f\u0627\u0621 \u0627\u0644\u0633\u0643\u0631\u064a \u0641\u064a \u0627\u0644\u0639\u0627\u0645 2019 \u0642\u062f \u064a\u0644\u063a \u0646\u062d\u0648 4.2 \u0645\u0644\u064a\u0648\u0646 \u0639\u0627\u0644\u0645\u064a\u0627\u064b.<sup>[8]<\/sup> \u0648\u064a\u062a\u0645\u064a\u0632 \u0627\u0644\u0646\u0645\u0637 \u0627\u0644\u062b\u0627\u0646\u064a \u0645\u0646 \u0627\u0644\u062f\u0627\u0621 \u0627\u0644\u0633\u0643\u0631\u064a T2DM\u060c \u0648\u0627\u0644\u0630\u064a \u064a\u0634\u0643\u0644 \u0646\u062d\u0648 90% \u0645\u0646 \u062d\u0627\u0644\u0627\u062a \u0627\u0644\u062f\u0627\u0621 \u0627\u0644\u0633\u0643\u0631\u064a \u0639\u0627\u0644\u0645\u064a\u0627\u064b\u060c<sup>[8]<\/sup> \u0628\u0622\u0644\u064a\u0629 \u0625\u0645\u0631\u0627\u0636\u064a\u0629 \u062a\u0628\u062f\u0623 \u0628\u0627\u0644\u0628\u062f\u0627\u0646\u0629 \u0648\u062a\u0628\u062f\u0644\u0627\u062a \u0641\u064a \u0627\u0644\u0646\u0633\u064a\u062c \u0627\u0644\u0634\u062d\u0645\u064a \u0648\u0648\u0638\u064a\u0641\u0629 \u0627\u0644\u062e\u0644\u064a\u0629 \u0627\u0644\u0634\u062d\u0645\u064a\u0629 \u062a\u062a\u0631\u0627\u0641\u0642 \u0645\u0639 \u062d\u062f\u062b\u064a\u0629 \u0627\u0644\u062a\u0647\u0627\u0628\u064a\u0629 \u0645\u0645\u0627 \u064a\u0642\u0648\u062f \u0625\u0644\u0649 \u0645\u0642\u0627\u0648\u0645\u0629 \u0627\u0644\u0623\u0646\u0633\u0648\u0644\u064a\u0646 (\u062a\u0639\u0637\u064a\u0644 \u0639\u0645\u0644 \u0627\u0644\u0623\u0646\u0633\u0648\u0644\u064a\u0646) \u0648\u0627\u0644\u0645\u062a\u0644\u0627\u0632\u0645\u0629 \u0627\u0644\u0627\u0633\u062a\u0642\u0644\u0627\u0628\u064a\u0629 \u0648\u062a\u0628\u062f\u0644\u0627\u062a \u0641\u064a \u0648\u0638\u064a\u0641\u0629 \u062e\u0644\u0627\u064a\u0627 \u0628\u064a\u062a\u0627 \u0627\u0644\u0628\u0646\u0643\u0631\u064a\u0627\u0633\u0629. \u0648\u062a\u0639\u0645\u0644 \u0647\u0630\u0647 \u0627\u0644\u0622\u0644\u064a\u0627\u062a \u0627\u0644\u0645\u062a\u0631\u0627\u0628\u0637\u0629\u060c \u0630\u0627\u062a \u0627\u0644\u062a\u0623\u062b\u064a\u0631 \u0627\u0644\u0645\u062a\u0628\u0627\u062f\u0644\u060c \u0639\u0644\u0649 \u062a\u0633\u0631\u064a\u0639 \u062d\u062f\u0648\u062b \u0627\u0644\u062f\u0627\u0621 \u0627\u0644\u0633\u0643\u0631\u064a \u0648\u0645\u0636\u0627\u0639\u0641\u0627\u062a\u0647 \u0627\u0644\u0645\u0632\u0645\u0646\u0629 \u0627\u0644\u0627\u0633\u062a\u0642\u0644\u0627\u0628\u064a\u0629 \u0648\u0627\u0644\u0642\u0644\u0628\u064a\u0629 \u0627\u0644\u0648\u0639\u0627\u0626\u064a\u0629\u060c<sup>[3, 8-21]<\/sup> \u0648\u0627\u0644\u062a\u064a \u062a\u0639\u062a\u0628\u0631 \u0645\u0635\u062f\u0631 \u062e\u0637\u0648\u0631\u0629 \u0627\u0644\u062f\u0627\u0621 \u0627\u0644\u0633\u0643\u0631\u064a \u0627\u0644\u0630\u064a \u064a\u0632\u064a\u062f \u0627\u062e\u062a\u0637\u0627\u0631 \u0645\u0631\u0636 \u0627\u0644\u0642\u0644\u0628 \u0627\u0644\u0625\u0642\u0641\u0627\u0631\u064a \u0628\u0645\u0642\u062f\u0627\u0631 2-3 \u0623\u0636\u0639\u0627\u0641 \u0645\u0642\u0627\u0631\u0646\u0629 \u0628\u063a\u064a\u0631 \u0627\u0644\u0633\u0643\u0631\u064a\u064a\u0646.<sup>[8, 21, 22]<\/sup> \u0648\u0628\u0630\u0644\u0643\u060c \u0641\u0627\u0644\u062f\u0627\u0621 \u0627\u0644\u0633\u0643\u0631\u064a \u0647\u0648 \u0623\u062d\u062f \u0639\u0648\u0627\u0645\u0644 \u0627\u062e\u062a\u0637\u0627\u0631 \u0627\u0644\u0623\u0645\u0631\u0627\u0636 \u0627\u0644\u0642\u0644\u0628\u064a\u0629 \u0627\u0644\u0648\u0639\u0627\u0626\u064a\u0629 \u0627\u0644\u0625\u0642\u0641\u0627\u0631\u064a\u0629 \u0627\u0644\u0645\u0633\u062a\u0642\u0644\u0629 \u0641\u0636\u0644\u0627\u064b \u0639\u0646 \u062a\u0631\u0627\u0641\u0642\u0647 \u0628\u0639\u0648\u0627\u0645\u0644 \u0627\u062e\u062a\u0637\u0627\u0631 \u0623\u062e\u0631\u0649 \u0648\u0645\u0646\u0647\u0627 \u0627\u0631\u062a\u0641\u0627\u0639 \u0636\u063a\u0637 \u0627\u0644\u062f\u0645 \u0648\u0627\u0644\u062d\u0627\u0644\u0629 \u0627\u0644\u0627\u0644\u062a\u0647\u0627\u0628\u064a\u0629 \u0648\u0627\u0644\u0628\u0631\u0648\u0641\u064a\u0644 \u0627\u0644\u0634\u062d\u0645\u064a \u0627\u0644\u0639\u0635\u064a\u062f\u064a (\u0627\u0631\u062a\u0641\u0627\u0639 \u0645\u0633\u062a\u0648\u064a\u0627\u062a \u0643\u0644 \u0645\u0646 \u0627\u0644\u0643\u0648\u0644\u064a\u0633\u062a\u0631\u0648\u0644 \u0627\u0644\u0625\u062c\u0645\u0627\u0644\u064a TC \u0648\u062b\u0644\u0627\u062b\u064a\u0627\u062a \u0623\u0633\u064a\u0644 \u0627\u0644\u063a\u0644\u064a\u0633\u064a\u0631\u0648\u0644 TAG \u0648\u0643\u0648\u0644\u0633\u062a\u0631\u0648\u0644 \u0627\u0644\u0628\u0631\u0648\u062a\u064a\u0646\u0627\u062a \u0627\u0644\u0634\u062d\u0645\u064a\u0629 \u0645\u0646\u062e\u0641\u0636\u0629 \u0627\u0644\u0643\u062b\u0627\u0641\u0629 LDL-C\u060c \u0645\u0639 \u0627\u0646\u062e\u0641\u0627\u0636 \u0643\u0648\u0644\u0633\u062a\u0631\u0648\u0644 \u0627\u0644\u0628\u0631\u0648\u062a\u064a\u0646\u0627\u062a \u0627\u0644\u0634\u062d\u0645\u064a\u0629 \u0645\u0631\u062a\u0641\u0639\u0629 \u0627\u0644\u0643\u062b\u0627\u0641\u0629 HDL-C \u0641\u064a \u0627\u0644\u0645\u0635\u0644) \u0627\u0644\u0646\u0627\u062c\u0645 \u0639\u0646 \u0645\u0642\u0627\u0648\u0645\u0629 \u0627\u0644\u0623\u0646\u0633\u0648\u0644\u064a\u0646.<sup>[6-9, 14, 18, 21, 22]. <\/sup><\/span><span style=\"font-family: 'times new roman', times, serif;\">\u0627\u0644\u0628\u062f\u0627\u0646\u0629 \u0645\u0631\u0636 \u0627\u0633\u062a\u0642\u0644\u0627\u0628\u064a \u0645\u062a\u0639\u062f\u062f \u0627\u0644\u0639\u0648\u0627\u0645\u0644 \u064a\u0646\u062c\u0645 \u0639\u0646 \u062a\u0622\u062b\u0631 \u0639\u0648\u0627\u0645\u0644 \u062c\u064a\u0646\u064a\u0629 \u0645\u0639 \u0639\u0648\u0627\u0645\u0644 \u0645\u062a\u0639\u0644\u0642\u0629 \u0628\u0646\u0645\u0637 \u0627\u0644\u062d\u064a\u0627\u0629 \u0648\u062a\u062a\u0645\u064a\u0632 \u0628\u0632\u064a\u0627\u062f\u0629 \u0645\u0641\u0631\u0637\u0629 \u0641\u064a \u062f\u0647\u0648\u0646 \u0627\u0644\u062c\u0633\u0645 \u0628\u0633\u0628\u0628 \u0639\u062f\u0645 \u0627\u0644\u062a\u0648\u0627\u0632\u0646 \u0628\u064a\u0646 \u0643\u0645\u064a\u0629 \u0627\u0644\u0637\u0639\u0627\u0645 \u0648\u0645\u0635\u0631\u0648\u0641 \u0627\u0644\u0637\u0627\u0642\u0629. \u0648\u0647\u064a \u0645\u0634\u0643\u0644\u0629 \u0635\u062d\u0629 \u0639\u0645\u0648\u0645\u064a\u0629 \u0639\u0627\u0644\u0645\u064a\u0629 \u062a\u062a\u0632\u0627\u064a\u062f \u0628\u0627\u0636\u0637\u0631\u0627\u062f \u0628\u0633\u0628\u0628 \u0632\u064a\u0627\u062f\u0629 \u0646\u0645\u0637 \u0627\u0644\u062d\u064a\u0627\u0629 \u0627\u0644\u0643\u0633\u0648\u0644 \u0648\u0627\u0644\u063a\u0630\u0627\u0621 \u0627\u0644\u063a\u0646\u064a \u0628\u0627\u0644\u0634\u062d\u0645\u064a\u0627\u062a \u0648\u0627\u0644\u0623\u0637\u0639\u0645\u0629 \u0627\u0644\u0645\u0639\u0644\u0628\u0629.<sup>[23-28]<\/sup> \u0648\u0642\u062f \u0623\u0638\u0647\u0631\u062a \u0627\u0644\u062f\u0631\u0627\u0633\u0627\u062a \u0627\u0644\u0648\u0628\u0627\u0626\u064a\u0629 \u062e\u0637\u0648\u0631\u0629 \u0627\u0644\u0628\u062f\u0627\u0646\u0629 \u0641\u064a \u062a\u0637\u0648\u0631 \u0623\u0645\u0631\u0627\u0636 \u0645\u062e\u062a\u0644\u0641\u0629 \u0645\u062b\u0644 \u0645\u0642\u0627\u0648\u0645\u0629 \u0627\u0644\u0623\u0646\u0633\u0648\u0644\u064a\u0646 \u0648\u0627\u0644\u0645\u062a\u0644\u0627\u0632\u0645\u0629 \u0627\u0644\u0627\u0633\u062a\u0642\u0644\u0627\u0628\u064a\u0629 \u0648\u0627\u0644\u0623\u0645\u0631\u0627\u0636 \u0627\u0644\u0642\u0644\u0628\u064a\u0629 \u0627\u0644\u0648\u0639\u0627\u0626\u064a\u0629 \u0648\u0627\u0644\u0646\u0645\u0637 \u0627\u0644\u062b\u0627\u0646\u064a \u0645\u0646 \u0627\u0644\u062f\u0627\u0621 \u0627\u0644\u0633\u0643\u0631\u064a \u0648\u0627\u0631\u062a\u0641\u0627\u0639 \u0636\u063a\u0637 \u0627\u0644\u062f\u0645 \u0648\u0628\u0639\u0636 \u0627\u0644\u0633\u0631\u0637\u0627\u0646\u0627\u062a.<sup>[5-7, 23-25, 29-32]<\/sup> \u0648\u062a\u0641\u064a\u062f \u0627\u0644\u062f\u0631\u0627\u0633\u0627\u062a \u0628\u0623\u0646 \u0627\u0644\u0628\u062f\u0627\u0646\u0629 \u062a\u062a\u0631\u0627\u0641\u0642 \u0645\u0639 \u0648\u062c\u0648\u062f \u0645\u0633\u062a\u0648\u064a\u0627\u062a \u0639\u0627\u0644\u064a\u0629 \u0645\u0646 \u0627\u0644\u0633\u064a\u062a\u0648\u0643\u064a\u0646\u0627\u062a \u0627\u0644\u0627\u0644\u062a\u0647\u0627\u0628\u064a\u0629 \u0648\u062d\u0627\u0644\u0629 \u0645\u0646 \u0627\u0644\u0627\u0644\u062a\u0647\u0627\u0628 \u0627\u0644\u0645\u0632\u0645\u0646 \u0645\u0646\u062e\u0641\u0636 \u0627\u0644\u062f\u0631\u062c\u0629\u060c<sup>[5, 7, 9, 12, 21, 33]<\/sup> \u0648\u0627\u0644\u0628\u062f\u0627\u0646\u0629 \u0627\u0644\u062d\u0634\u0648\u064a\u0629 \u062e\u0635\u0648\u0635\u0627\u064b \u0648\u0627\u0644\u0627\u0644\u062a\u0647\u0627\u0628 \u062f\u0627\u062e\u0644 \u0627\u0644\u0646\u0633\u064a\u062c \u0627\u0644\u0634\u062d\u0645\u064a \u0627\u0644\u0623\u0628\u064a\u0636 \u064a\u0645\u0643\u0646 \u0623\u0646 \u064a\u0643\u0648\u0646\u0627 \u062e\u0637\u0648\u0629 \u062d\u0627\u0633\u0645\u0629 \u0641\u064a \u0627\u0644\u0625\u0633\u0647\u0627\u0645 \u0641\u064a \u0638\u0647\u0648\u0631 \u0645\u0642\u0627\u0648\u0645\u0629 \u0627\u0644\u0623\u0646\u0633\u0648\u0644\u064a\u0646 \u0648\u0627\u0644\u0646\u0645\u0637 \u0627\u0644\u062b\u0627\u0646\u064a \u0645\u0646 \u0627\u0644\u062f\u0627\u0621 \u0627\u0644\u0633\u0643\u0631\u064a \u0648\u0627\u0644\u062a\u0635\u0644\u0628 \u0627\u0644\u0639\u0635\u064a\u062f\u064a.<sup>[5-7, 9, 18, 21, 29, 31, 33-35] <\/sup><\/span><span style=\"font-family: 'times new roman', times, serif;\">\u0644\u0645 \u064a\u0639\u062f \u0645\u0642\u0628\u0648\u0644\u0627\u064b \u0627\u0644\u0646\u0638\u0631 \u0625\u0644\u0649 \u0627\u0644\u0646\u0633\u064a\u062c \u0627\u0644\u0634\u062d\u0645\u064a \u0639\u0644\u0649 \u0623\u0646\u0651\u0647 \u0639\u0636\u0648 \u062e\u0627\u0645\u0644 \u062a\u0642\u062a\u0635\u0631 \u0648\u0638\u064a\u0641\u062a\u0647 \u0639\u0644\u0649 \u062e\u0632\u0646 \u0627\u0644\u0637\u0627\u0642\u0629\u060c \u0641\u0642\u062f \u0623\u0638\u0647\u0631\u062a \u0627\u0644\u062f\u0631\u0627\u0633\u0627\u062a \u0623\u0646\u0647 \u064a\u064f\u0646\u062a\u062c \u0643\u0645\u064a\u0629 \u0643\u0628\u064a\u0631\u0629 \u0645\u0646 \u0645\u0648\u0627\u062f \u0627\u0644\u0625\u0634\u0639\u0627\u0631 \u0627\u0644\u0641\u0639\u0627\u0644\u0629 \u0627\u0644\u062a\u064a \u062a\u0645\u0627\u0631\u0633 \u062a\u0623\u062b\u064a\u0631\u0627\u062a \u0639\u0644\u0649 \u0639\u0645\u0644\u064a\u0627\u062a \u0628\u064a\u0648\u0644\u0648\u062c\u064a\u0629 \u0645\u062e\u062a\u0644\u0641\u0629 \u0628\u0645\u0627 \u0641\u064a \u0630\u0644\u0643 \u0627\u0644\u0627\u0644\u062a\u0647\u0627\u0628 \u0648\u0627\u0644\u0639\u0645\u0644\u064a\u0627\u062a \u0627\u0644\u0627\u0633\u062a\u0642\u0644\u0627\u0628\u064a\u0629.<sup>[31, 36, 37]<\/sup> \u0648\u064a\u064f\u0630\u0643\u0631\u064f \u0647\u0646\u0627 \u0625\u0641\u0631\u0627\u0632 \u0627\u0644\u0646\u0633\u064a\u062c \u0627\u0644\u0634\u062d\u0645\u064a \u0644\u0644\u0639\u062f\u064a\u062f \u0645\u0646 \u0627\u0644\u0647\u0631\u0645\u0648\u0646\u0627\u062a \u0627\u0644\u0628\u0628\u062a\u064a\u062f\u064a\u0629 \u0645\u062b\u0644 \u0627\u0644\u0623\u062f\u064a\u0628\u0648\u0646\u064a\u0643\u062a\u064a\u0646 adiponectin \u0648\u0627\u0644\u0631\u064a\u0632\u064a\u0633\u062a\u064a\u0646 resistin\u060c \u0641\u0636\u0644\u0627\u064b \u0639\u0646 \u0645\u062c\u0645\u0648\u0639\u0629 \u0645\u062a\u0646\u0648\u0639\u0629 \u0645\u0646 \u0645\u0648\u0627\u062f \u0627\u0644\u0625\u0634\u0639\u0627\u0631 \u0627\u0644\u0628\u0631\u0648\u062a\u064a\u0646\u064a\u0629 protein signals \u0627\u0644\u062a\u064a \u062a\u062f\u0639\u0649 \u0645\u062c\u062a\u0645\u0639\u0629\u064b \u0628\u0627\u0633\u0645 \u0627\u0644\u0633\u064a\u062a\u0648\u0643\u064a\u0646\u0627\u062a \u0627\u0644\u0634\u062d\u0645\u064a\u0629 (\u0627\u0644\u0645\u062d\u0631\u0643\u0627\u062a \u0627\u0644\u062e\u0644\u0648\u064a\u0629 \u0627\u0644\u0634\u062d\u0645\u064a\u0629 \u0623\u0648 \u0627\u0644\u0623\u062f\u064a\u0628\u0648\u0633\u064a\u062a\u0648\u0643\u064a\u0646\u0627\u062a adipocytokines)\u060c<sup>[38]<\/sup> \u0648\u0627\u0644\u062a\u064a \u062a\u0634\u0627\u0631\u0643 \u062c\u0645\u064a\u0639\u0647\u0627 \u0641\u064a \u062a\u0646\u0638\u064a\u0645 \u0627\u0644\u0637\u0627\u0642\u0629 \u0648\u0627\u0633\u062a\u0642\u0644\u0627\u0628 \u0627\u0644\u0634\u062d\u0645\u064a\u0627\u062a \u0648\u0627\u0644\u0633\u0643\u0631\u064a\u0627\u062a \u0648\u062a\u0646\u0638\u064a\u0645 \u0636\u063a\u0637 \u0627\u0644\u062f\u0645. \u0648\u0642\u062f \u0631\u064f\u0628\u0637\u062a \u0627\u0644\u0645\u062d\u0631\u0643\u0627\u062a \u0627\u0644\u062e\u0644\u0648\u064a\u0629 \u0627\u0644\u0634\u062d\u0645\u064a\u0629 \u0628\u0637\u0631\u064a\u0642\u0629 \u062a\u0637\u0648\u0631 \u0645\u0642\u0627\u0648\u0645\u0629 \u0627\u0644\u0623\u0646\u0633\u0648\u0644\u064a\u0646 \u0648\u0627\u0644\u062d\u0627\u0644\u0629 \u0627\u0644\u0627\u0644\u062a\u0647\u0627\u0628\u064a\u0629 \u0648\u0627\u0644\u0645\u062a\u0644\u0627\u0632\u0645\u0629 \u0627\u0644\u0627\u0633\u062a\u0642\u0644\u0627\u0628\u064a\u0629 \u0648\u0627\u0644\u0646\u0645\u0637 \u0627\u0644\u062b\u0627\u0646\u064a \u0645\u0646 \u0627\u0644\u062f\u0627\u0621 \u0627\u0644\u0633\u0643\u0631\u064a \u0648\u0627\u0636\u0637\u0631\u0627\u0628 \u0634\u062d\u0645\u064a\u0627\u062a \u0627\u0644\u062f\u0645 \u0648\u0627\u0644\u0623\u0645\u0631\u0627\u0636 \u0627\u0644\u0642\u0644\u0628\u064a\u0629 \u0627\u0644\u0648\u0639\u0627\u0626\u064a\u0629.<sup>[5, 7, 9, 13, 18, 21, 29, 31, 34, 36-38]<\/sup><\/span><\/p>\n<p style=\"text-align: justify;\"><strong><span style=\"font-family: 'times new roman', times, serif;\">\u0627\u0644\u0623\u062f\u064a\u0628\u0648\u0646\u0643\u062a\u064a\u0646 adiponectin<\/span><\/strong><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-family: 'times new roman', times, serif;\">\u0647\u0648 \u0623\u062d\u062f \u0627\u0644\u0645\u062d\u0631\u0643\u0627\u062a \u0627\u0644\u0634\u062d\u0645\u064a\u0629 \u0627\u0644\u0625\u0634\u0639\u0627\u0631\u064a\u0629 \u0648\u064a\u0646\u062a\u062c\u0647 \u0627\u0644\u0646\u0633\u064a\u062c \u0627\u0644\u0634\u062d\u0645\u064a \u062a\u062d\u062a \u0627\u0644\u062c\u0644\u062f \u0628\u0634\u0643\u0644 \u0631\u0626\u064a\u0633\u060c \u0648\u064a\u062a\u0643\u0648\u0646 \u0645\u0646 244 \u062d\u0645\u0636\u0627\u064b \u0623\u0645\u064a\u0646\u064a\u0627\u064b \u0628\u0648\u0632\u0646 \u062c\u0632\u064a\u0626\u064a \u064a\u0628\u0644\u063a \u0646\u062d\u0648 28-30 \u0643\u064a\u0644\u0648 \u062f\u0627\u0644\u062a\u0648\u0646.<sup>[31, 39-41]<\/sup> \u064a\u0639\u0645\u0644 \u0627\u0644\u0623\u062f\u064a\u0628\u0648\u0646\u0643\u062a\u064a\u0646 \u0639\u0628\u0631 \u0646\u0648\u0639\u064a\u0646 \u0645\u0646 \u0627\u0644\u0645\u0633\u062a\u0642\u0628\u0644\u0627\u062a \u0647\u0645\u0627 AdipoR1 \u0648AdipoR2 \u064a\u0648\u062c\u062f\u0627\u0646 \u0641\u064a \u0627\u0644\u0646\u0633\u064a\u062c \u0627\u0644\u0634\u062d\u0645\u064a \u0648\u0627\u0644\u0643\u0628\u062f \u0628\u064a\u0646\u0645\u0627 \u064a\u062d\u062a\u0648\u064a \u0627\u0644\u0639\u0636\u0644 \u0627\u0644\u0647\u064a\u0643\u0644\u064a \u0639\u0644\u0649 \u0627\u0644\u0646\u0648\u0639 \u0627\u0644\u0623\u0648\u0644 \u0641\u0642\u0637.<sup>[31, 42, 43]<\/sup> \u0648\u062a\u062a\u0636\u0645\u0646 \u062a\u0623\u062b\u064a\u0631\u0627\u062a\u0647 \u0627\u0644\u0645\u062a\u0646\u0648\u0639\u0629 \u0632\u064a\u0627\u062f\u0629 \u0627\u0644\u062d\u0633\u0627\u0633\u064a\u0629 \u0644\u0644\u0623\u0646\u0633\u0648\u0644\u064a\u0646 (\u0627\u0644\u062a\u0623\u062b\u064a\u0631 \u0627\u0644\u0645\u0636\u0627\u062f \u0644\u0644\u0633\u0643\u0631\u064a) \u0648\u0632\u064a\u0627\u062f\u0629 \u0623\u0643\u0633\u062f\u0629 \u0627\u0644\u062d\u0645\u0648\u0636 \u0627\u0644\u062f\u0647\u0646\u064a\u0629 \u0648\u0625\u0646\u0642\u0627\u0635 \u062a\u062d\u0631\u0631 \u0627\u0644\u063a\u0644\u0648\u0643\u0648\u0632 \u0645\u0646 \u0627\u0644\u0643\u0628\u062f (\u0646\u0642\u0635 \u0627\u0633\u062a\u062d\u062f\u0627\u062b \u0627\u0644\u063a\u0644\u0648\u0643\u0648\u0632) \u0648\u0632\u064a\u0627\u062f\u0629 \u0642\u0628\u0637 \u0627\u0644\u063a\u0644\u0648\u0643\u0648\u0632 \u0648\u062a\u062e\u0644\u064a\u0642 \u0627\u0644\u062f\u0647\u0648\u0646 \u0641\u0636\u0644\u0627\u064b \u0639\u0646 \u0632\u064a\u0627\u062f\u0629 \u0627\u0633\u062a\u0642\u0644\u0627\u0628 \u0627\u0644\u063a\u0644\u0648\u0643\u0648\u0632 \u0648\u0623\u0643\u0633\u062f\u0629 \u0627\u0644\u062d\u0645\u0648\u0636 \u0627\u0644\u062f\u0647\u0646\u064a\u0629 \u0641\u064a \u0627\u0644\u0639\u0636\u0644 \u0627\u0644\u0647\u064a\u0643\u0644\u064a.<sup>[31, 43-45]<\/sup> \u0648\u062a\u0634\u064a\u0631 \u0627\u0644\u062f\u0631\u0627\u0633\u0627\u062a \u0625\u0644\u0649 \u0623\u0646 \u0645\u0633\u062a\u0648\u064a\u0627\u062a \u0627\u0644\u0623\u062f\u064a\u0628\u0648\u0646\u0643\u062a\u064a\u0646 \u062a\u0646\u0642\u0635 \u0639\u0646\u062f \u0627\u0644\u0628\u062f\u064a\u0646\u064a\u0646 \u0648\u0645\u0631\u0636\u0649 \u0627\u0644\u0627\u0636\u0637\u0631\u0627\u0628\u0627\u062a \u0627\u0644\u0627\u0633\u062a\u0642\u0644\u0627\u0628\u064a\u0629 \u0627\u0644\u0642\u0644\u0628\u064a\u0629\u060c \u0648\u062a\u0632\u062f\u0627\u062f \u0645\u0639 \u0627\u0646\u062e\u0641\u0627\u0636 \u0627\u0644\u0648\u0632\u0646. \u0643\u0645\u0627 \u064a\u0646\u0642\u0635 \u0625\u0641\u0631\u0627\u0632\u0647 \u0641\u064a \u062d\u0627\u0644\u0627\u062a \u0641\u0631\u0637 \u0623\u0646\u0633\u0648\u0644\u064a\u0646 \u0627\u0644\u062f\u0645 \u0648\u0627\u0644\u0643\u0631\u0628 \u0627\u0644\u062a\u0623\u0643\u0633\u062f\u064a \u0648\u0627\u0644\u0627\u0644\u062a\u0647\u0627\u0628 \u0627\u0644\u0645\u0644\u062d\u0648\u0638\u0629 \u0641\u064a \u0627\u0644\u0628\u062f\u0627\u0646\u0629. \u0648\u0643\u0630\u0644\u0643 \u064a\u0646\u0642\u0635 \u0625\u0641\u0631\u0627\u0632\u0647 \u0628\u0641\u0639\u0644 \u0627\u0644\u0648\u0633\u0627\u0626\u0637 \u0627\u0644\u0627\u0644\u062a\u0647\u0627\u0628\u064a\u0629 \u0645\u0645\u0627 \u064a\u0648\u062d\u064a \u0628\u0623\u0646 \u0627\u0644\u0627\u0644\u062a\u0647\u0627\u0628 \u0642\u062f \u064a\u0643\u0648\u0646 \u0627\u0644\u0639\u0627\u0645\u0644 \u0627\u0644\u0631\u0626\u064a\u0633 \u0627\u0644\u0645\u0633\u0647\u0645 \u0641\u064a \u0646\u0642\u0635 \u0645\u0633\u062a\u0648\u064a\u0627\u062a \u0627\u0644\u0623\u062f\u064a\u0628\u0648\u0646\u0643\u062a\u064a\u0646 \u0641\u064a \u062d\u0627\u0644\u0627\u062a \u0645\u0642\u0627\u0648\u0645\u0629 \u0627\u0644\u0623\u0646\u0633\u0648\u0644\u064a\u0646 \u0648\u0627\u0644\u0628\u062f\u0627\u0646\u0629.<sup>[31, 44-49]<\/sup> \u0643\u0645\u0627 \u062a\u0648\u062d\u064a \u0627\u0644\u062f\u0631\u0627\u0633\u0627\u062a \u0628\u0623\u0646 \u0627\u0644\u0623\u062f\u064a\u0628\u0648\u0646\u0643\u062a\u064a\u0646 \u0642\u062f \u064a\u0645\u0646\u0639 \u0627\u0644\u062a\u0635\u0644\u0628 \u0627\u0644\u0639\u0635\u064a\u062f\u064a \u0645\u0646 \u062e\u0644\u0627\u0644 \u0623\u0641\u0639\u0627\u0644\u0647 \u0627\u0644\u0645\u0630\u0643\u0648\u0631\u0629 \u0623\u0639\u0644\u0627\u0647 \u0641\u0636\u0644\u0627\u064b \u0639\u0646 \u062e\u0641\u0636 \u062a\u0634\u0643\u064a\u0644 \u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u0631\u063a\u0648\u064a\u0629 \u0648\u0627\u0644\u062d\u062f\u062b\u064a\u0629 \u0627\u0644\u0627\u0644\u062a\u0647\u0627\u0628\u064a\u0629.<sup>[31, 50]<\/sup> \u0648\u0627\u0644\u0645\u0639\u0637\u064a\u0627\u062a \u0627\u0644\u0633\u0627\u0628\u0642\u0629 \u0643\u0644\u0647\u0627 \u062a\u0648\u062d\u064a \u0628\u062f\u0648\u0631 \u0644\u0644\u0623\u062f\u064a\u0628\u0648\u0646\u0643\u062a\u064a\u0646 \u0641\u064a \u0625\u0645\u0631\u0627\u0636\u064a\u0629 \u0627\u0644\u0646\u0645\u0637 \u0627\u0644\u062b\u0627\u0646\u064a \u0645\u0646 \u0627\u0644\u062f\u0627\u0621 \u0627\u0644\u0633\u0643\u0631\u064a \u0645\u0639 \u0627\u062d\u062a\u0645\u0627\u0644 \u0648\u062c\u0648\u062f \u0639\u0644\u0627\u0642\u0629 \u0628\u064a\u0646 \u0645\u0633\u062a\u0648\u064a\u0627\u062a\u0647 \u0648\u0628\u0639\u0636 \u0639\u0648\u0627\u0645\u0644 \u0627\u0644\u0627\u062e\u062a\u0637\u0627\u0631 \u0627\u0644\u0642\u0644\u0628\u064a\u0629 \u0627\u0644\u0648\u0639\u0627\u0626\u064a\u0629 \u0627\u0644\u062a\u064a \u062a\u0632\u064a\u062f \u0639\u0646\u062f \u0645\u0631\u0636\u0649 \u0627\u0644\u0633\u0643\u0631\u064a \u0645\u062b\u0644 \u0627\u0636\u0637\u0631\u0627\u0628 \u0627\u0644\u0634\u062d\u0645\u064a\u0627\u062a \u0648\u0627\u0644\u062d\u0627\u0644\u0629 \u0627\u0644\u0627\u0644\u062a\u0647\u0627\u0628\u064a\u0629 \u0648\u0645\u0642\u0627\u0648\u0645\u0629 \u0627\u0644\u0623\u0646\u0633\u0648\u0644\u064a\u0646 \u0648\u063a\u064a\u0631\u0647\u0627.<\/span><\/p>\n<p style=\"text-align: justify;\"><strong><span style=\"font-family: 'times new roman', times, serif;\">\u0627\u0644\u0631\u064a\u0632\u064a\u0633\u062a\u064a\u0646 Resistin<\/span><\/strong><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-family: 'times new roman', times, serif;\">\u0647\u0648 \u0639\u062f\u064a\u062f \u0628\u0628\u062a\u064a\u062f \u063a\u0646\u064a \u0628\u0627\u0644\u0633\u064a\u0633\u062a\u0626\u064a\u0646 \u0648\u064a\u062a\u0643\u0648\u0646 \u0645\u0646 108 \u062d\u0645\u0648\u0636 \u0623\u0645\u064a\u0646\u064a\u0629\u060c \u0648\u064a\u0628\u0644\u063a \u0648\u0632\u0646\u0647 \u0627\u0644\u062c\u0632\u064a\u0626\u064a 11.3 \u0643\u064a\u0644\u0648 \u062f\u0627\u0644\u062a\u0648\u0646. \u0648\u064a\u0641\u0631\u0632 \u0639\u0646\u062f \u0627\u0644\u0628\u0634\u0631 \u0628\u0634\u0643\u0644 \u0631\u0626\u064a\u0633 \u0645\u0646 \u0627\u0644\u0628\u0627\u0644\u0639\u0627\u062a \u0648\u0627\u0644\u0648\u062d\u064a\u062f\u0627\u062a \u0636\u0645\u0646 \u0627\u0644\u0646\u0633\u064a\u062c \u0627\u0644\u0634\u062d\u0645\u064a \u0648\u0645\u0646 \u0637\u0644\u0627\u0626\u0639 \u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u0634\u062d\u0645\u064a\u0629.<sup>[31, 51]<\/sup> \u0625\u0646\u0647 \u064a\u0642\u0627\u0648\u0645 \u0639\u0645\u0644 \u0627\u0644\u0623\u0646\u0633\u0648\u0644\u064a\u0646\u060c \u0648\u0645\u0646 \u0647\u0646\u0627 \u062c\u0627\u0621 \u0627\u0633\u0645\u0647\u060c \u0648\u064a\u062d\u062f\u062b \u062e\u0644\u0644\u0627 \u0641\u064a \u0627\u0633\u062a\u062a\u0628\u0627\u0628 \u0627\u0644\u063a\u0644\u0648\u0643\u0648\u0632 \u0639\u0646\u062f \u0627\u0644\u062c\u0631\u0630\u0627\u0646 \u0645\u0645\u0627 \u064a\u0642\u0648\u062f \u0625\u0644\u0649 \u062a\u0637\u0648\u0631 \u0627\u0644\u0646\u0645\u0637 \u0627\u0644\u062b\u0627\u0646\u064a \u0645\u0646 \u0627\u0644\u062f\u0627\u0621 \u0627\u0644\u0633\u0643\u0631\u064a. \u0648\u064a\u0628\u062f\u0648 \u0623\u0646\u0647 \u0627\u0644\u0631\u0627\u0628\u0637 \u0628\u064a\u0646 \u0627\u0644\u0628\u062f\u0627\u0646\u0629 \u0627\u0644\u062d\u0634\u0648\u064a\u0629 \u0648\u0645\u0642\u0627\u0648\u0645\u0629 \u0627\u0644\u0623\u0646\u0633\u0648\u0644\u064a\u0646.<sup>[51-53] <\/sup><\/span><span style=\"font-family: 'times new roman', times, serif;\">\u0645\u0646\u0630 \u0627\u0643\u062a\u0634\u0627\u0641 \u0627\u0644\u0631\u064a\u0632\u064a\u0633\u062a\u064a\u0646 \u0641\u064a \u0627\u0644\u0639\u0627\u0645 2001\u060c \u0648\u0627\u0644\u062a\u0639\u0627\u0631\u0636 \u0645\u0648\u062c\u0648\u062f \u062d\u0648\u0644 \u062f\u0648\u0631\u0647 \u0641\u064a \u0627\u0644\u0625\u0646\u0633\u0627\u0646. \u0648\u0631\u063a\u0645 \u0627\u0644\u0645\u0639\u0637\u064a\u0627\u062a \u0627\u0644\u0642\u0648\u064a\u0629 \u0639\u0646 \u062a\u0623\u062b\u064a\u0631\u0627\u062a\u0647 \u0627\u0644\u0645\u0631\u0636\u064a\u0629 \u0641\u064a \u0627\u0644\u062c\u0631\u0630\u0627\u0646\u060c \u0628\u0645\u0627 \u0641\u064a \u0630\u0644\u0643 \u0627\u0633\u062a\u062a\u0628\u0627\u0628 \u0627\u0644\u0623\u0646\u0633\u0648\u0644\u064a\u0646 \u0648\u0645\u0642\u0627\u0648\u0645\u062a\u0647<sup>[54, 55]<\/sup>\u060c \u0625\u0644\u0627 \u0623\u0646\u0647\u060c \u0648\u0644\u0633\u0648\u0621 \u0627\u0644\u062d\u0638\u060c \u0644\u0645 \u064a\u0643\u0646 \u0645\u0645\u0643\u0646\u0627\u064b \u062a\u0637\u0628\u064a\u0642 \u0647\u0630\u0647 \u0627\u0644\u0645\u0639\u0644\u0648\u0645\u0627\u062a \u0639\u0644\u0649 \u0627\u0644\u0628\u0634\u0631 \u0644\u0623\u0633\u0628\u0627\u0628 \u0639\u062f\u0629 \u0623\u0647\u0645\u0647\u0627 \u0627\u0644\u0645\u0633\u062a\u0648\u0649 \u0627\u0644\u0645\u0646\u062e\u0641\u0636 \u0645\u0646 \u0627\u0644\u062a\u062c\u0627\u0646\u0633 \u0628\u064a\u0646 \u0631\u064a\u0632\u064a\u0633\u062a\u064a\u0646 \u0627\u0644\u0628\u0634\u0631 \u0648\u0627\u0644\u062c\u0631\u0630\u0627\u0646 \u0648\u0627\u0644\u0630\u064a \u0644\u0645 \u064a\u062a\u062c\u0627\u0648\u0632 35% \u0645\u0646 \u0627\u0644\u062d\u0645\u0648\u0636 \u0627\u0644\u0623\u0645\u064a\u0646\u064a\u0629<sup>[52]<\/sup>. \u0648\u0628\u0642\u064a\u062a \u0627\u0644\u0639\u0644\u0627\u0642\u0629 \u0628\u064a\u0646 \u0645\u0633\u062a\u0648\u064a\u0627\u062a\u0647 \u0627\u0644\u0645\u0635\u0644\u064a\u0629 \u0648\u0627\u0644\u0646\u0645\u0637 \u0627\u0644\u062b\u0627\u0646\u064a \u0645\u0646 \u0627\u0644\u062f\u0627\u0621 \u0627\u0644\u0633\u0643\u0631\u064a \u0623\u0648 \u0645\u0642\u0627\u0648\u0645\u0629 \u0627\u0644\u0623\u0646\u0633\u0648\u0644\u064a\u0646 \u0623\u0648 \u0627\u0644\u0628\u062f\u0627\u0646\u0629 \u063a\u064a\u0631 \u0648\u0627\u0636\u062d\u0629 \u0639\u0646\u062f \u0627\u0644\u0625\u0646\u0633\u0627\u0646 \u0643\u0645\u0627 \u0628\u0642\u064a \u0627\u0631\u062a\u0628\u0627\u0637 \u0627\u0644\u0645\u0633\u062a\u0648\u064a\u0627\u062a \u0627\u0644\u0639\u0627\u0644\u064a\u0629 \u0645\u0646\u0647 \u0645\u0639 \u0647\u0630\u0647 \u0627\u0644\u062d\u0627\u0644\u0627\u062a \u0627\u0644\u0645\u0631\u0636\u064a\u0629 \u0645\u062b\u0627\u0631\u0627\u064b \u0644\u0644\u062c\u062f\u0644<sup>[31, 51, 56-58]<\/sup>. \u0648\u0642\u062f \u0623\u0643\u062f\u062a \u0627\u0644\u0645\u0631\u0627\u062c\u0639\u0627\u062a \u0627\u0644\u062d\u062f\u064a\u062b\u0629 \u0647\u0630\u0627 \u0627\u0644\u062a\u0639\u0627\u0631\u0636 \u0641\u064a \u0646\u062a\u0627\u0626\u062c \u0627\u0644\u062f\u0631\u0627\u0633\u0627\u062a \u0639\u0644\u0649 \u0627\u0644\u0631\u064a\u0632\u064a\u0633\u062a\u064a\u0646 \u0648\u062f\u0648\u0631\u0647 \u0641\u064a \u0627\u0644\u062a\u0633\u0628\u0628 \u0628\u0645\u0642\u0627\u0648\u0645\u0629 \u0627\u0644\u0623\u0646\u0633\u0648\u0644\u064a\u0646 \u0648\u0627\u0644\u0627\u0633\u062a\u062c\u0627\u0628\u0629 \u0627\u0644\u0627\u0644\u062a\u0647\u0627\u0628\u064a\u0629 \u0648\u062a\u062d\u0631\u064a\u0636 \u062a\u0646\u0634\u064a\u0637 \u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u0628\u0637\u0627\u0646\u064a\u0629 \u0627\u0644\u0648\u0639\u0627\u0626\u064a\u0629 \u0627\u0644\u0630\u064a \u064a\u0641\u0636\u064a \u0625\u0644\u0649 \u0627\u0644\u062a\u0635\u0644\u0628 \u0627\u0644\u0639\u0635\u064a\u062f\u064a \u0639\u0646\u062f \u0627\u0644\u0625\u0646\u0633\u0627\u0646.<sup>[21, 31, 51, 58-60]<\/sup> \u0643\u0645\u0627 \u0623\u0638\u0647\u0631 \u0642\u064a\u0627\u0633 \u0645\u0633\u062a\u0648\u064a\u0627\u062a \u0627\u0644\u0631\u064a\u0632\u064a\u0633\u062a\u064a\u0646 \u0639\u0646\u062f \u0627\u0644\u0645\u0635\u0627\u0628\u064a\u0646 \u0628\u0627\u0644\u0628\u062f\u0627\u0646\u0629 \u063a\u064a\u0631 \u0627\u0644\u0635\u062d\u064a\u0629 \u0627\u0633\u062a\u0642\u0644\u0627\u0628\u064a\u0627\u064b \u0648\u0627\u0644\u0628\u062f\u0627\u0646\u0629 \u0627\u0644\u0633\u0648\u064a\u0629 \u0627\u0633\u062a\u0642\u0644\u0627\u0628\u064a\u0627\u064b \u0646\u062a\u0627\u0626\u062c \u0645\u062a\u0646\u0627\u0642\u0636\u0629\u060c \u0641\u0636\u0644\u0627\u064b \u0639\u0646 \u0625\u0638\u0647\u0627\u0631 \u0627\u0644\u0631\u064a\u0632\u064a\u0633\u062a\u064a\u0646 \u0643\u0648\u0627\u0635\u0645 \u0627\u0644\u062a\u0647\u0627\u0628\u064a \u0641\u064a \u062d\u0627\u0644\u0629 \u0627\u0644\u062a\u0635\u0644\u0628 \u0627\u0644\u0639\u0635\u064a\u062f\u064a.<sup>[31, 51, 61-63] <\/sup><\/span><span style=\"font-family: 'times new roman', times, serif;\">\u062a\u0648\u062d\u064a \u0627\u0644\u0645\u0639\u0637\u064a\u0627\u062a \u0627\u0644\u0633\u0627\u0628\u0642\u0629 \u0643\u0644\u0647\u0627 \u0628\u0623\u0646 \u0641\u0647\u0645 \u0627\u0644\u0639\u0644\u0627\u0642\u0627\u062a \u0627\u0644\u0645\u062d\u062a\u0645\u0644\u0629 \u0644\u0644\u0623\u062f\u064a\u0628\u0648\u0646\u0643\u062a\u064a\u0646 \u0648\u0627\u0644\u0631\u064a\u0632\u0633\u062a\u064a\u0646 \u0645\u0639 \u0625\u0645\u0631\u0627\u0636\u064a\u0629 \u0627\u0644\u0628\u062f\u0627\u0646\u0629 \u0648\u0627\u0644\u062d\u0627\u0644\u0629 \u0627\u0644\u0627\u0644\u062a\u0647\u0627\u0628\u064a\u0629 \u0648\u0645\u0642\u0627\u0648\u0645\u0629 \u0627\u0644\u0623\u0646\u0633\u0648\u0644\u064a\u0646 \u0648\u0627\u0644\u0646\u0645\u0637 \u0627\u0644\u062b\u0627\u0646\u064a \u0645\u0646 \u0627\u0644\u062f\u0627\u0621 \u0627\u0644\u0633\u0643\u0631\u064a \u0648\u0639\u0648\u0627\u0645\u0644 \u0627\u0644\u0627\u062e\u062a\u0637\u0627\u0631 \u0627\u0644\u0642\u0644\u0628\u064a\u0629 \u0627\u0644\u0648\u0639\u0627\u0626\u064a\u0629 \u0631\u0628\u0645\u0627 \u064a\u0633\u0627\u0645 \u0641\u064a \u062a\u0648\u062c\u064a\u0647 \u062e\u0637\u0648\u0627\u062a \u0627\u0644\u0631\u0639\u0627\u064a\u0629 \u0627\u0644\u0635\u062d\u064a\u0629 \u0646\u062d\u0648 \u0627\u0644\u062a\u062e\u0641\u064a\u0641 \u0645\u0646 \u0639\u0648\u0627\u0645\u0644 \u0627\u0644\u0627\u062e\u062a\u0637\u0627\u0631 \u0647\u0630\u0647 \u0648\u0627\u0644\u062a\u0642\u0644\u064a\u0644 \u0645\u0646 \u0627\u0646\u062a\u0634\u0627\u0631 \u0627\u0644\u0623\u0645\u0631\u0627\u0636 \u0627\u0644\u0642\u0644\u0628\u064a\u0629 \u0627\u0644\u0648\u0639\u0627\u0626\u064a\u0629\u060c \u0627\u0644\u0633\u0628\u0628 \u0627\u0644\u0623\u0648\u0644 \u0644\u0644\u0648\u0641\u064a\u0627\u062a \u0648\u0627\u0644\u0625\u0639\u0627\u0642\u0629 \u0639\u0627\u0644\u0645\u064a\u0627\u064b. \u0648\u0647\u062f\u0641 \u0647\u0630\u0627 \u0627\u0644\u0628\u062d\u062b \u0647\u0648 \u0645\u062d\u0627\u0648\u0644\u0629 \u0627\u0633\u062a\u0643\u0634\u0627\u0641 \u0639\u0644\u0627\u0642\u0629 \u0647\u0630\u064a\u0646 \u0627\u0644\u0647\u0631\u0645\u0648\u0646\u064a\u0646 \u0645\u0639 \u0645\u0642\u0627\u0648\u0645\u0629 \u0627\u0644\u0623\u0646\u0633\u0648\u0644\u064a\u0646 \u0648\u0639\u0648\u0627\u0645\u0644 \u0627\u0644\u0627\u062e\u062a\u0637\u0627\u0631 \u0627\u0644\u0642\u0644\u0628\u064a\u0629 \u0627\u0644\u0648\u0639\u0627\u0626\u064a\u0629 \u0627\u0644\u0627\u0633\u062a\u0642\u0644\u0627\u0628\u064a\u0629 \u0648\u0627\u0644\u0627\u0644\u062a\u0647\u0627\u0628\u064a\u0629.<\/span><\/p>\n<p style=\"text-align: justify;\"><strong><span style=\"font-family: 'times new roman', times, serif;\">\u0627\u0644\u0645\u0648\u0627\u062f \u0648\u0627\u0644\u0637\u0631\u0627\u0626\u0642 Materials and Methods<\/span><\/strong><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-family: 'times new roman', times, serif;\"><strong>\u0645\u0643\u0627\u0646 \u0627\u0644\u062f\u0631\u0627\u0633\u0629 \u0648\u0625\u062c\u0627\u0632\u062a\u0647\u0627 \u0648\u0627\u0644\u0645\u0634\u0627\u0631\u0643\u0648\u0646: <\/strong>\u0643\u0627\u0646\u062a \u0625\u062c\u0627\u0632\u0629 \u0625\u062c\u0631\u0627\u0621 \u0647\u0630\u0627 \u0627\u0644\u0628\u062d\u062b \u0645\u0646 \u0642\u0628\u0644 \u0645\u062c\u0644\u0633 \u062c\u0627\u0645\u0639\u0629 \u062f\u0645\u0634\u0642 \u0628\u0639\u062f \u0645\u0648\u0627\u0641\u0642\u0629 \u0645\u062c\u0644\u0633 \u0643\u0644\u064a\u0629 \u0627\u0644\u0637\u0628 \u0627\u0644\u0628\u0634\u0631\u064a \u0627\u0644\u062a\u064a \u0623\u062c\u0631\u064a\u062a \u0627\u062e\u062a\u0628\u0627\u0631\u0627\u062a \u0627\u0644\u062f\u0631\u0627\u0633\u0629 \u0641\u064a \u0645\u062e\u0627\u0628\u0631\u0647\u0627 \u0641\u064a \u062d\u064a\u0646 \u0627\u062e\u062a\u064a\u0631 \u0627\u0644\u0645\u0634\u0627\u0631\u0643\u0648\u0646 \u0641\u064a \u0627\u0644\u062f\u0631\u0627\u0633\u0629 \u0639\u0634\u0648\u0627\u0626\u064a\u0627\u064b \u0645\u0646 \u0645\u0634\u0641\u0649 \u0627\u0644\u0645\u0648\u0627\u0633\u0627\u0629 \u0627\u0644\u062c\u0627\u0645\u0639\u064a \u0628\u062f\u0645\u0634\u0642 (\u0648\u0632\u0627\u0631\u0629 \u0627\u0644\u062a\u0639\u0644\u064a\u0645 \u0627\u0644\u0639\u0627\u0644\u064a \u0648\u0627\u0644\u0628\u062d\u062b \u0627\u0644\u0639\u0644\u0645\u064a) \u0648\u0627\u0644\u0639\u064a\u0627\u062f\u0627\u062a \u0627\u0644\u0634\u0627\u0645\u0644\u0629 \u0627\u0644\u062a\u0627\u0628\u0639\u0629 \u0644\u0648\u0632\u0627\u0631\u0629 \u0627\u0644\u0635\u062d\u0629. \u0648\u0642\u062f \u0634\u0645\u0644\u062a \u0627\u0644\u062f\u0631\u0627\u0633\u0629 159 \u0634\u062e\u0635\u0627\u064b (79 \u0623\u0646\u062b\u0649 \u064880 \u0630\u0643\u0631\u0627\u064b) \u062a\u0645 \u062a\u0648\u0632\u064a\u0639\u0647\u0645 \u0639\u0644\u0649 \u062b\u0644\u0627\u062b \u0645\u062c\u0645\u0648\u0639\u0627\u062a: (1) \u0645\u062c\u0645\u0648\u0639\u0629 \u0627\u0644\u0634\u0648\u0627\u0647\u062f: 40 \u0634\u062e\u0635\u0627\u064b \u0645\u0646 \u0627\u0644\u0623\u0633\u0648\u064a\u0627\u0621 \u0638\u0627\u0647\u0631\u064a\u0627\u064b (19 \u0623\u0646\u062b\u0649 \u064821 \u0630\u0643\u0631\u0627\u064b) \u0648\u0627\u0644\u0645\u0642\u0627\u0631\u0628\u064a\u0646 \u0644\u0645\u062c\u0645\u0648\u0639\u0629 \u0627\u0644\u0645\u0631\u0636\u0649 \u0645\u0646 \u062d\u064a\u062b \u0627\u0644\u062c\u0646\u0633 \u0648\u0627\u0644\u0639\u0645\u0631\u061b (2) \u0645\u062c\u0645\u0648\u0639\u0629 \u0645\u0631\u0636\u0649 \u0627\u0644\u0646\u0645\u0637 \u0627\u0644\u062b\u0627\u0646\u064a \u0645\u0646 \u0627\u0644\u062f\u0627\u0621 \u0627\u0644\u0633\u0643\u0631\u064a \u063a\u064a\u0631 \u0627\u0644\u0645\u0635\u0627\u0628\u064a\u0646 \u0628\u0645\u0631\u0636 \u0627\u0644\u0625\u0642\u0641\u0627\u0631 \u0627\u0644\u0642\u0644\u0628\u064a IHD: 60 \u0645\u0631\u064a\u0636\u0627\u064b (29 \u0623\u0646\u062b\u0649 \u064831 \u0630\u0643\u0631\u0627\u064b)\u061b (3) \u0645\u062c\u0645\u0648\u0639\u0629 \u0645\u0631\u0636\u0649 \u0627\u0644\u0646\u0645\u0637 \u0627\u0644\u062b\u0627\u0646\u064a \u0645\u0646 \u0627\u0644\u062f\u0627\u0621 \u0627\u0644\u0633\u0643\u0631\u064a \u0627\u0644\u0645\u0635\u0627\u0628\u064a\u0646 \u0628\u0645\u0631\u0636 \u0627\u0644\u0625\u0642\u0641\u0627\u0631 \u0627\u0644\u0642\u0644\u0628\u064a: 59 \u0645\u0631\u064a\u0636\u0627\u064b (31 \u0623\u0646\u062b\u0649 \u064828 \u0630\u0643\u0631\u0627\u064b). \u0648\u0628\u0627\u0644\u0625\u0636\u0627\u0641\u0629 \u0625\u0644\u0649 \u062f\u0631\u0627\u0633\u0629 \u0647\u0630\u0647 \u0627\u0644\u0645\u062c\u0645\u0648\u0639\u0627\u062a \u0627\u0644\u062b\u0644\u0627\u062b \u0628\u0648\u0635\u0641\u0647\u0627 \u0645\u062c\u0645\u0648\u0639\u0627\u062a \u0645\u0633\u062a\u0642\u0644\u0629\u060c \u0641\u0642\u062f \u062a\u0636\u0645\u0646\u062a \u0627\u0644\u062f\u0631\u0627\u0633\u0627\u062a \u0627\u0644\u0625\u062d\u0635\u0627\u0626\u064a\u0629 \u0641\u064a \u0647\u0630\u0627 \u0627\u0644\u0628\u062d\u062b \u0623\u064a\u0636\u0627\u064b \u0627\u0639\u062a\u0628\u0627\u0631 \u0627\u0644\u0645\u062c\u0645\u0648\u0639\u062a\u064a\u0646 \u0627\u0644\u062b\u0627\u0646\u064a\u0629 \u0648\u0627\u0644\u062b\u0627\u0644\u062b\u0629 \u0643\u0645\u062c\u0645\u0648\u0639\u0629 \u0648\u0627\u062d\u062f\u0629 \u0633\u0645\u064a\u0651\u062a \u0645\u062c\u0645\u0648\u0639\u0629 \u0627\u0644\u0645\u0631\u0636\u0649 \u0627\u0644\u0633\u0643\u0631\u064a\u064a\u0646\u060c \u0648\u0634\u0645\u0644\u062a 119 \u0645\u0631\u064a\u0636\u0627\u064b \u0628\u0627\u0644\u0646\u0645\u0637 \u0627\u0644\u062b\u0627\u0646\u064a \u0645\u0646 \u0627\u0644\u062f\u0627\u0621 \u0627\u0644\u0633\u0643\u0631\u064a (60 \u0623\u0646\u062b\u0649 \u064859 \u0630\u0643\u0631\u0627\u064b).<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-family: 'times new roman', times, serif;\"><strong>\u0645\u0639\u0627\u064a\u064a\u0631 \u0627\u0644\u0627\u0633\u062a\u0628\u0639\u0627\u062f:<\/strong> \u0627\u0644\u0645\u0631\u0636 \u0627\u0644\u0645\u0632\u0645\u0646 \u0645\u062b\u0644 \u0627\u0644\u0642\u0635\u0648\u0631 \u0627\u0644\u0643\u0644\u0648\u064a \u0623\u0648 \u0627\u0644\u0645\u0631\u0636 \u0627\u0644\u0643\u0628\u062f\u064a\u060c \u0648\u0627\u0644\u0645\u0634\u0627\u0643\u0644 \u0627\u0644\u063a\u062f\u064a\u0629 \u0627\u0644\u0635\u0645\u0627\u0648\u064a\u0629 \u0648\u062e\u0635\u0648\u0635\u0627\u064b \u062f\u0627\u0621 \u0643\u0648\u0634\u064a\u0646\u063a \u0648\u0627\u0644\u0627\u0636\u0637\u0631\u0627\u0628\u0627\u062a \u0627\u0644\u062f\u0631\u0642\u064a\u0629\u060c \u0648\u0627\u0644\u0633\u064a\u062f\u0627\u062a \u0627\u0644\u062d\u0648\u0627\u0645\u0644 \u0648\u0627\u0644\u0645\u0631\u0636\u0639\u0627\u062a\u060c \u0648\u0627\u0644\u0645\u0631\u0636\u0649 \u0627\u0644\u0630\u064a\u0646 \u064a\u062a\u0646\u0627\u0648\u0644\u0648\u0646 \u0639\u0644\u0627\u062c\u0627\u062a \u062f\u0648\u0627\u0626\u064a\u0629 \u0633\u062a\u064a\u0631\u0648\u0626\u064a\u062f\u064a\u0629 \u0642\u0634\u0631\u064a\u0629 \u0623\u0648 \u0645\u0636\u0627\u062f\u0627\u062a \u0627\u0644\u0627\u0643\u062a\u0626\u0627\u0628 \u0623\u0648 \u0645\u0636\u0627\u062f\u0627\u062a \u0627\u0644\u0627\u0644\u062a\u0647\u0627\u0628 \u063a\u064a\u0631 \u0627\u0644\u0633\u062a\u064a\u0631\u0648\u0626\u064a\u062f\u064a\u0629\u060c \u0648\u0627\u0644\u0643\u062d\u0648\u0644\u064a\u0648\u0646 \u0648\u0627\u0644\u0645\u062f\u062e\u0646\u0648\u0646\u060c \u0648\u0648\u062c\u0648\u062f \u0642\u0635\u0629 \u0627\u0646\u062e\u0641\u0627\u0636 \u0648\u0632\u0646 \u0623\u0643\u062b\u0631 \u0645\u0646 3 \u0643\u063a \u062e\u0644\u0627\u0644 \u0627\u0644\u0634\u0647\u0631\u064a\u0646 \u0627\u0644\u0645\u0627\u0636\u064a\u064a\u0646 \u0623\u0648 \u062c\u0631\u0627\u062d\u0629 \u062d\u062f\u064a\u062b\u0629 \u0623\u0648 \u0646\u0638\u0627\u0645 \u062d\u0645\u064a\u0629 \u063a\u0630\u0627\u0626\u064a\u0629 \u062e\u0627\u0635\u0629 \u062e\u0644\u0627\u0644 \u0627\u0644\u0623\u0634\u0647\u0631 \u0627\u0644\u0633\u062a\u0629 \u0627\u0644\u0645\u0627\u0636\u064a\u0629 \u0623\u0648 \u062a\u0646\u0627\u0648\u0644 \u0645\u0639\u0627\u0644\u062c\u0629 \u062f\u0648\u0627\u0626\u064a\u0629 \u0623\u0648 \u0628\u062f\u064a\u0644\u0629 \u0623\u0648 \u0645\u062a\u0645\u0645\u0629 \u062a\u062e\u0641\u0636 \u0648\u0632\u0646 \u0627\u0644\u062c\u0633\u0645 \u0623\u0648 \u0634\u062d\u0645\u064a\u0627\u062a \u0627\u0644\u062f\u0645 \u0623\u0648 \u0627\u0644\u0623\u062f\u0648\u064a\u0629 \u0645\u0646 \u0635\u0646\u0641 Thiazolidinediones (TZDs).<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-family: 'times new roman', times, serif;\"><strong>\u0646\u0648\u0639 \u0627\u0644\u062f\u0631\u0627\u0633\u0629 \u0648\u0632\u0645\u0646 \u0625\u062c\u0631\u0627\u0626\u0647\u0627:<\/strong> \u0627\u0644\u062f\u0631\u0627\u0633\u0629 \u0645\u0646 \u0646\u0645\u0637 \u0627\u0644\u062d\u0627\u0644\u0629 &#8211; \u0627\u0644\u0634\u0627\u0647\u062f \u0648\u0642\u062f \u0623\u062c\u0631\u064a\u062a \u0641\u064a \u0627\u0644\u0641\u062a\u0631\u0629 \u0645\u0627 \u0628\u064a\u0646 \u062a\u0634\u0631\u064a\u0646 \u0627\u0644\u062b\u0627\u0646\u064a 2018 \u0648\u0622\u0628 2020.<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-family: 'times new roman', times, serif;\"><strong>\u062a\u0634\u062e\u064a\u0635 \u0627\u0644\u062f\u0627\u0621 \u0627\u0644\u0633\u0643\u0631\u064a \u0648\u0627\u0644\u0625\u0642\u0641\u0627\u0631 \u0627\u0644\u0642\u0644\u0628\u064a:<\/strong> \u062c\u0631\u0649 \u062a\u0634\u062e\u064a\u0635 \u0627\u0644\u062f\u0627\u0621 \u0627\u0644\u0633\u0643\u0631\u064a \u0627\u0633\u062a\u0646\u0627\u062f\u0627\u064b \u0625\u0644\u0649 \u0645\u0639\u0627\u064a\u064a\u0631 \u0645\u0646\u0638\u0645\u0629 \u0627\u0644\u0635\u062d\u0629 \u0627\u0644\u0639\u0627\u0644\u0645\u064a\u0629 (2019) \u0628\u062d\u064a\u062b \u064a\u0643\u0648\u0646 \u0627\u0644\u0634\u062e\u0635 \u0645\u0631\u064a\u0636\u0627\u064b \u0628\u0627\u0644\u062f\u0627\u0621 \u0627\u0644\u0633\u0643\u0631\u064a \u0625\u0630\u0627 \u0643\u0627\u0646 \u0633\u0643\u0631 \u0627\u0644\u062f\u0645 \u0627\u0644\u0635\u064a\u0627\u0645\u064a 126 \u0645\u0644\u063a\/\u062f\u0644 \u0641\u0645\u0627 \u0641\u0648\u0642.<strong><sup>[22]<\/sup><\/strong> \u0623\u0645\u0627 \u062a\u0634\u062e\u064a\u0635 \u0645\u0631\u0636 \u0627\u0641\u0642\u0641\u0627\u0631 \u0627\u0644\u0642\u0644\u0628\u064a \u0641\u0642\u062f \u0627\u0639\u062a\u0645\u062f \u0639\u0644\u0649 \u0645\u0639\u0627\u064a\u064a\u0631 \u0645\u0646\u0638\u0645\u0629 \u0627\u0644\u0635\u062d\u0629 \u0627\u0644\u0639\u0627\u0644\u0645\u064a\u0629 \u0627\u0644\u062a\u064a \u062a\u062a\u0636\u0645\u0646 \u0642\u0635\u0629 \u0627\u0644\u0623\u0644\u0645 \u0627\u0644\u0646\u0645\u0648\u0630\u062c\u064a \u0648\u0632\u064a\u0627\u062f\u0629 \u0627\u0644\u0648\u0627\u0635\u0645\u0627\u062a \u0627\u0644\u0643\u064a\u0645\u064a\u0627\u0626\u064a\u0629 \u0627\u0644\u062d\u064a\u0648\u064a\u0629 \u0627\u0644\u0642\u0644\u0628\u064a\u0629 \u0648\u0627\u0644\u062a\u0628\u062f\u0644\u0627\u062a \u0627\u0644\u0645\u0634\u062e\u0635\u0629 \u0641\u064a \u062a\u062e\u0637\u064a\u0637 \u0627\u0644\u0642\u0644\u0628 \u0627\u0644\u0643\u0647\u0631\u0628\u064a\u061b \u0648\u064a\u0643\u0648\u0646 \u0627\u0644\u062a\u0634\u062e\u064a\u0635 \u0625\u064a\u062c\u0627\u0628\u064a\u0627\u064b \u0625\u0630\u0627 \u062a\u062d\u0642\u0642 \u0627\u062b\u0646\u064a\u0646 \u0641\u0623\u0643\u062b\u0631 \u0645\u0646 \u0647\u0630\u0647 \u0627\u0644\u0645\u0639\u0627\u064a\u064a\u0631<strong><sup>[64]<\/sup><\/strong>.<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-family: 'times new roman', times, serif;\"><strong>\u0642\u064a\u0627\u0633 \u0636\u063a\u0637 \u0627\u0644\u062f\u0645 \u0648\u0645\u0646\u0633\u0628 \u0643\u062a\u0644\u0629 \u0627\u0644\u062c\u0633\u0645 <\/strong><strong>BMI<\/strong><strong>:<\/strong> \u062c\u0631\u0649 \u0627\u0644\u062d\u0635\u0648\u0644 \u0639\u0644\u0649 \u062c\u0645\u064a\u0639 \u0627\u0644\u0642\u064a\u0627\u0633\u0627\u062a \u0648\u062a\u0633\u062c\u064a\u0644\u0647\u0627 \u0641\u064a \u0627\u0644\u0635\u0628\u0627\u062d \u0628\u0639\u062f \u0635\u064a\u0627\u0645 14 \u0633\u0627\u0639\u0629 \u0648\u0641\u0642\u064b\u0627 \u0644\u0644\u0628\u0631\u0648\u062a\u0648\u0643\u0648\u0644\u0627\u062a \u0627\u0644\u0645\u0646\u0634\u0648\u0631\u0629. \u062a\u0645 \u0642\u064a\u0627\u0633 \u0636\u063a\u0637 \u0627\u0644\u062f\u0645 \u0645\u0631\u062a\u064a\u0646 (\u0628\u0641\u0627\u0635\u0644 10 \u062f\u0642\u0627\u0626\u0642) \u0628\u0648\u0636\u0639\u064a\u0629 \u0627\u0644\u062c\u0644\u0648\u0633 \u0628\u0639\u062f \u0631\u0627\u062d\u0629 \u0644\u0645\u062f\u0629 10-15 \u062f\u0642\u064a\u0642\u0629 \u0648\u0645\u0646 \u062b\u0645 \u062a\u0633\u062c\u064a\u0644 \u0645\u062a\u0648\u0633\u0637 \u0627\u0644\u0642\u064a\u0627\u0633\u064a\u0646. \u0623\u0645\u0627 \u0645\u0646\u0633\u0628 \u0643\u062a\u0644\u0629 \u0627\u0644\u062c\u0633\u0645 (\u0643\u063a\/\u0645<sup>2<\/sup>) \u0641\u0642\u062f \u062a\u0645 \u062d\u0633\u0627\u0628\u0647 \u0628\u0642\u0633\u0645\u0629 \u0648\u0632\u0646 \u0627\u0644\u062c\u0633\u0645 (\u0627\u0644\u0645\u0633\u062c\u0644 \u0639\u0644\u0649 \u0645\u0642\u064a\u0627\u0633 \u0631\u0642\u0645\u064a \u0645\u064f\u0639\u0627\u064a\u0631\u060c \u0645\u0639 \u0627\u0631\u062a\u062f\u0627\u0621 \u0645\u0644\u0627\u0628\u0633 \u062e\u0641\u064a\u0641\u0629 \u0641\u0642\u0637 \u0648\u062f\u0648\u0646 \u0623\u062d\u0630\u064a\u0629) \u0639\u0644\u0649 \u0645\u0631\u0628\u0639 \u0637\u0648\u0644 \u0627\u0644\u062c\u0633\u0645 \u0628\u0648\u0636\u0639\u064a\u0629 \u0627\u0644\u0648\u0642\u0648\u0641.<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-family: 'times new roman', times, serif;\"><strong>\u0627\u0639\u062a\u064a\u0627\u0646 \u0627\u0644\u062f\u0645 \u0648\u0627\u0644\u0642\u064a\u0627\u0633\u0627\u062a \u0627\u0644\u0643\u064a\u0645\u064a\u0627\u0626\u064a\u0629 \u0627\u0644\u062d\u064a\u0648\u064a\u0629:<\/strong> \u0628\u0639\u062f \u0635\u064a\u0627\u0645 \u0644\u064a\u0644\u0629 \u0643\u0627\u0645\u0644\u0629 (14 \u0633\u0627\u0639\u0629)\u060c \u062c\u0631\u0649 \u062c\u0645\u0639 \u0639\u064a\u0646\u0627\u062a \u0627\u0644\u062f\u0645 \u0627\u0644\u0648\u0631\u064a\u062f\u064a \u0641\u064a \u0623\u0646\u0627\u0628\u064a\u0628 \u0645\u062e\u062a\u0644\u0641\u0629 \u0644\u0644\u062d\u0635\u0648\u0644 \u0639\u0644\u0649 \u0627\u0644\u0628\u0644\u0627\u0632\u0645\u0627 \u0648\u0627\u0644\u0645\u0635\u0644. \u062a\u0645 \u0641\u0635\u0644 \u0627\u0644\u0639\u064a\u0646\u0627\u062a \u0625\u0644\u0649 \u0623\u062c\u0632\u0627\u0621 \u0648\u062a\u062c\u0645\u064a\u062f\u0647\u0627 \u0641\u0648\u0631\u0627\u064b \u0639\u0646\u062f \u062f\u0631\u062c\u0629 \u0627\u0644\u062d\u0631\u0627\u0631\u0629 20 \u062f\u0631\u062c\u0629 \u0645\u0626\u0648\u064a\u0629 \u062a\u062d\u062a \u0627\u0644\u0635\u0641\u0631 \u062d\u062a\u0649 \u0645\u0648\u0639\u062f \u0625\u062c\u0631\u0627\u0621 \u0627\u0644\u0642\u064a\u0627\u0633\u0627\u062a \u0627\u0644\u0643\u064a\u0645\u064a\u0627\u0626\u064a\u0629 \u0627\u0644\u062d\u064a\u0648\u064a\u0629. \u0648\u0642\u062f \u0642\u064a\u0633 \u0645\u0633\u062a\u0648\u0649 \u0627\u0644\u063a\u0644\u0648\u0643\u0648\u0632 \u0641\u064a \u0627\u0644\u0628\u0644\u0627\u0632\u0645\u0627 (\u0628\u0627\u0633\u062a\u062e\u062f\u0627\u0645 EDTA \u0643\u0645\u0636\u0627\u062f \u062a\u062e\u062b\u0631) \u0648\u0634\u062d\u0645\u064a\u0627\u062a \u0627\u0644\u0645\u0635\u0644 \u0628\u0627\u0644\u0637\u0631\u0627\u0626\u0642 \u0627\u0644\u0644\u0648\u0646\u064a\u0629 \u0628\u0627\u0633\u062a\u062e\u062f\u0627\u0645 \u0637\u0648\u0627\u0642\u0645 \u0627\u0644\u0643\u0648\u0627\u0634\u0641 \u0627\u0644\u0645\u0639\u0631\u0648\u0641\u0629. \u0623\u0645\u0627 \u0627\u0644\u0623\u0646\u0633\u0648\u0644\u064a\u0646 \u0641\u062a\u0645\u062a \u0645\u0639\u0627\u064a\u0631\u062a\u0647 \u0628\u0627\u0633\u062a\u062e\u062f\u0627\u0645 \u0637\u0627\u0642\u0645 \u0643\u0648\u0627\u0634\u0641 \u0628\u0637\u0631\u064a\u0642\u0629 \u0645\u0642\u0627\u064a\u0633\u0629 \u0627\u0644\u0645\u0645\u062a\u0632 \u0627\u0644\u0645\u0646\u0627\u0639\u064a \u0627\u0644\u0645\u0631\u062a\u0628\u0637 \u0628\u0627\u0644\u0625\u0646\u0632\u064a\u0645 (ELISA)\u060c \u0628\u064a\u0646\u0645\u0627 \u062a\u0645 \u0642\u064a\u0627\u0633 CRP \u0628\u0627\u0644\u0637\u0631\u064a\u0642\u0629 \u0627\u0644\u0639\u0643\u0631\u064a\u0629. <\/span><span style=\"font-family: 'times new roman', times, serif;\">\u0627\u0633\u062a\u064f\u062e\u062f\u0645 \u063a\u0644\u0648\u0643\u0648\u0632 \u0627\u0644\u0628\u0644\u0627\u0632\u0645\u0627 \u0627\u0644\u0635\u064a\u0627\u0645\u064a (FPG) \u0648\u0645\u0633\u062a\u0648\u064a\u0627\u062a \u0627\u0644\u0623\u0646\u0633\u0648\u0644\u064a\u0646 \u0627\u0644\u0635\u064a\u0627\u0645\u064a \u0644\u062d\u0633\u0627\u0628 \u0645\u062f\u0649 \u0645\u0642\u0627\u0648\u0645\u0629 \u0627\u0644\u0623\u0646\u0633\u0648\u0644\u064a\u0646 (HOMA-IR) \u0645\u0646 \u062e\u0644\u0627\u0644 \u0627\u0644\u0645\u0639\u0627\u062f\u0644\u0629 \u0627\u0644\u062a\u0627\u0644\u064a\u0629<strong><sup>[65]<\/sup><\/strong>:<\/span><\/p>\n<p style=\"text-align: center;\"><span style=\"font-family: 'times new roman', times, serif;\">HOMA-IR = [\u0627\u0644\u0623\u0646\u0633\u0648\u0644\u064a\u0646 (\u0645\u064a\u0643\u0631\u0648 \u0648\u062d\u062f\u0629 \u062f\u0648\u0644\u064a\u0629\/\u0645\u0644) \u00d7 \u063a\u0644\u0648\u0643\u0648\u0632 \u0627\u0644\u0628\u0644\u0627\u0632\u0645\u0627 (\u0645\u0644\u063a\/\u062f\u0644) \u00f7 405]<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-family: 'times new roman', times, serif;\">\u062c\u0631\u0649 \u062d\u0633\u0627\u0628 \u0645\u0633\u062a\u0648\u0649 \u0627\u0644\u0643\u0648\u0644\u064a\u0633\u062a\u0631\u0648\u0644 \u062e\u0627\u0631\u062c \u0627\u0644\u0628\u0631\u0648\u062a\u064a\u0646\u0627\u062a \u0627\u0644\u0634\u062d\u0645\u064a\u0629 \u0645\u0631\u062a\u0641\u0639\u0629 \u0627\u0644\u0643\u062b\u0627\u0641\u0629 non-HDL-C (\u0645\u0644\u063a\/\u062f\u0644) \u0628\u0637\u0631\u062d \u0645\u0633\u062a\u0648\u0649 HDL-C (\u0645\u0644\u063a\/\u062f\u0644) \u0645\u0646 \u0645\u0633\u062a\u0648\u0649 \u0643\u0648\u0644\u064a\u0633\u062a\u0631\u0648\u0644 \u0627\u0644\u0645\u0635\u0644 \u0627\u0644\u0625\u062c\u0645\u0627\u0644\u064a TC (\u0645\u0644\u063a\/\u062f\u0644)\u061b \u0628\u064a\u0646\u0645\u0627 \u062a\u0645 \u062a\u0642\u062f\u064a\u0631 \u0645\u0633\u062a\u0648\u0649 \u0643\u0648\u0644\u064a\u0633\u062a\u0631\u0648\u0644 \u0627\u0644\u0628\u0631\u0648\u062a\u064a\u0646\u0627\u062a \u0627\u0644\u0634\u062d\u0645\u064a\u0629 \u0645\u0646\u062e\u0641\u0636\u0629 \u0627\u0644\u0643\u062b\u0627\u0641\u0629 LDL-C (\u0645\u0644\u063a\/\u062f\u0644) \u0645\u0646 \u0642\u064a\u0645 HDL-C \u0648TC \u0648TAG \u0628\u0627\u0633\u062a\u062e\u062f\u0627\u0645 \u0645\u0639\u0627\u062f\u0644\u0629 \u0641\u0631\u064a\u062f\u0648\u0627\u0644\u062f<strong><sup>[66]<\/sup><\/strong>:<\/span><\/p>\n<p style=\"text-align: center;\"><span style=\"font-family: 'times new roman', times, serif;\">LDL-C = TC \u2012 [HDL-C + (TAG \u00f7 5)]<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-family: 'times new roman', times, serif;\"><strong>\u0627\u0644\u0627\u0639\u062a\u0628\u0627\u0631\u0627\u062a \u0627\u0644\u0623\u062e\u0644\u0627\u0642\u064a\u0629:<\/strong> \u062a\u0645 \u0634\u0631\u062d \u0627\u0644\u062f\u0631\u0627\u0633\u0629 \u0648\u0627\u0644\u063a\u0631\u0636 \u0645\u0646\u0647\u0627 \u0644\u0643\u0644 \u0627\u0644\u0645\u0634\u0627\u0631\u0643\u064a\u0646 \u0627\u0644\u0630\u064a\u0646 \u0623\u064f\u0628\u0644\u063a\u0648\u0627 \u0623\u064a\u0636\u0627\u064b \u0628\u062d\u0642\u0647\u0645 \u0641\u064a \u0625\u0646\u0647\u0627\u0621 \u0645\u0634\u0627\u0631\u0643\u062a\u0647\u0645 \u0641\u064a \u0627\u0644\u062f\u0631\u0627\u0633\u0629 \u0641\u064a \u0623\u064a \u0648\u0642\u062a \u062f\u0648\u0646 \u0623\u064a \u062a\u0623\u062b\u064a\u0631 \u0639\u0644\u0649 \u0631\u0639\u0627\u064a\u062a\u0647\u0645 \u0627\u0644\u0635\u062d\u064a\u0629. \u0643\u0645\u0627 \u0648\u0642\u0651\u0639 \u0627\u0644\u0645\u0634\u0627\u0631\u0643\u0648\u0646 (\u0623\u0648 \u0642\u062f\u0645\u0648\u0627 \u0634\u0641\u0647\u064a\u0627\u064b \u0641\u064a \u0628\u0639\u0636 \u0627\u0644\u0623\u062d\u064a\u0627\u0646) \u0639\u0644\u0649 \u0627\u0644\u0645\u0648\u0627\u0641\u0642\u0629 \u0627\u0644\u0645\u0633\u062a\u0646\u064a\u0631\u0629.<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-family: 'times new roman', times, serif;\"><strong>\u0627\u0644\u062a\u062d\u0644\u064a\u0644 \u0627\u0644\u0625\u062d\u0635\u0627\u0626\u064a:<\/strong> \u0623\u062c\u0631\u064a\u062a \u0627\u0644\u0627\u062e\u062a\u0628\u0627\u0631\u0627\u062a \u0627\u0644\u0625\u062d\u0635\u0627\u0626\u064a\u0629 \u0628\u0627\u0633\u062a\u062e\u062f\u0627\u0645 \u0627\u0644\u0625\u0635\u062f\u0627\u0631 22.0 \u0645\u0646 \u0628\u0631\u0645\u062c\u064a\u0627\u062a SPSS (\u0634\u0631\u0643\u0629 IBM Inc.\u060c \u0634\u064a\u0643\u0627\u063a\u0648\u060c \u0627\u0644\u0648\u0644\u0627\u064a\u0627\u062a \u0627\u0644\u0645\u062a\u062d\u062f\u0629 \u0627\u0644\u0623\u0645\u0631\u064a\u0643\u064a\u0629). \u0648\u0639\u064f\u0631\u0636\u062a \u0627\u0644\u0646\u062a\u0627\u0626\u062c \u0639\u0644\u0649 \u0634\u0643\u0644 \u0645\u062a\u0648\u0633\u0637 \u00b1 \u0627\u0646\u062d\u0631\u0627\u0641 \u0645\u0639\u064a\u0627\u0631\u064a SD. \u0648\u062a\u0645\u062a \u0645\u0642\u0627\u0631\u0646\u0629 \u0642\u064a\u0645 \u0627\u0644\u0645\u062a\u0648\u0633\u0637\u0627\u062a \u0628\u0627\u0633\u062a\u062e\u062f\u0627\u0645 \u0627\u062e\u062a\u0628\u0627\u0631 \u062a\u062d\u0644\u064a\u0644 \u0627\u0644\u062a\u0628\u0627\u064a\u0646 \u0623\u062d\u0627\u062f\u064a \u0627\u0644\u0627\u062a\u062c\u0627\u0647 (one-way ANOVA) \u0645\u062a\u0628\u0648\u0639\u0627\u064b \u0628\u0627\u062e\u062a\u0628\u0627\u0631 \u0628\u0648\u0646\u0641\u064a\u0631\u0648\u0646\u064a Bonferroni (\u0644\u0643\u0634\u0641 \u0635\u0645\u0648\u062f \u0627\u0644\u062a\u0628\u0627\u064a\u0646 \u0628\u064a\u0646 \u0627\u0644\u0645\u062c\u0645\u0648\u0639\u062a\u064a\u0646 \u0627\u0644\u062b\u0627\u0646\u064a\u0629 \u0648\u0627\u0644\u062b\u0627\u0644\u062b\u0629) \u0623\u0648 \u0627\u062e\u062a\u0628\u0627\u0631 t-test. \u0623\u0645\u0627 \u0627\u0644\u0627\u0631\u062a\u0628\u0627\u0637\u0627\u062a correlations \u0628\u064a\u0646 \u0627\u0644\u0645\u062a\u063a\u064a\u0631\u0627\u062a \u0641\u0642\u062f \u0642\u064f\u064a\u0651\u0645\u062a \u0628\u0627\u0633\u062a\u062e\u062f\u0627\u0645 \u0645\u0639\u0627\u0645\u0644 \u0627\u0631\u062a\u0628\u0627\u0637 \u0628\u064a\u0631\u0633\u0648\u0646 \u0645\u062a\u0628\u0648\u0639\u0627\u064b \u0628\u062a\u062d\u0644\u064a\u0644 \u0627\u0644\u062a\u062d\u0648\u0641 \u0627\u0644\u0625\u0645\u062f\u0627\u062f\u064a \u0627\u0644\u062b\u0646\u0627\u0626\u064a logistic binary regression. \u0628\u0627\u0644\u0625\u0636\u0627\u0641\u0629 \u0644\u0630\u0644\u0643\u060c \u0641\u0642\u062f \u0627\u0633\u062a\u064f\u062e\u0631\u062c\u062a \u0645\u0633\u0627\u062d\u0629 \u0627\u0644\u0645\u0646\u0637\u0642\u0629 \u0627\u0644\u0648\u0627\u0642\u0639\u0629 \u0623\u0633\u0641\u0644 \u0645\u0646\u062d\u0646\u0649 AUC \u062e\u0627\u0635\u064a\u0629 \u062a\u0634\u063a\u064a\u0644 \u0627\u0644\u0645\u0633\u062a\u0642\u0628\u0644 ROC. \u0648\u0641\u064a \u0643\u0644 \u0627\u0644\u062d\u0627\u0644\u0627\u062a \u062a\u0645 \u0627\u0639\u062a\u0628\u0627\u0631 \u0642\u064a\u0645\u0629 P \u0627\u0644\u0623\u0642\u0644 \u0645\u0646 0.05 \u0630\u0627\u062a \u062f\u0644\u0627\u0644\u0629 \u0625\u062d\u0635\u0627\u0626\u064a\u0629.<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-family: 'times new roman', times, serif;\"><strong>\u00a0<\/strong><strong>\u0627\u0644\u0646\u062a\u0627\u0626\u062c <\/strong><strong>Results<\/strong><\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-family: 'times new roman', times, serif;\">\u064a\u064e\u0639\u0631\u0636 \u0627\u0644\u062c\u062f\u0648\u0644 (1) \u062a\u0648\u0632\u0639 \u0627\u0644\u0645\u0634\u0627\u0631\u0643\u064a\u0646 \u0639\u0644\u0649 \u0627\u0644\u0645\u062c\u0645\u0648\u0639\u0627\u062a \u0627\u0644\u062b\u0644\u0627\u062b \u0648\u0645\u0642\u0627\u0631\u0646\u0629 \u0627\u0644\u0623\u0639\u0645\u0627\u0631 \u0648\u0627\u0644\u062c\u0646\u0633 \u0648\u0645\u0646\u0633\u0628 \u0643\u062a\u0644\u0629 \u0627\u0644\u062c\u0633\u0645 \u0641\u064a\u0645\u0627 \u0628\u064a\u0646\u0647\u0627. \u0648\u0647\u0648 \u064a\u0638\u0647\u0631 \u0627\u0644\u062a\u0648\u0627\u0641\u0642 \u0628\u064a\u0646 \u0645\u062c\u0645\u0648\u0639\u0627\u062a \u0627\u0644\u062f\u0631\u0627\u0633\u0629 \u0627\u0644\u062b\u0644\u0627\u062b \u0645\u0646 \u062d\u064a\u062b \u0627\u0644\u0639\u0645\u0631 \u0648\u0627\u0644\u062c\u0646\u0633 (<em>P<\/em><em> &gt; 0.01<\/em>). \u0623\u0645\u0627 \u0645\u0646\u0633\u0628 \u0643\u062a\u0644\u0629 \u0627\u0644\u062c\u0633\u0645 BMI \u0641\u0642\u062f \u0643\u0627\u0646 \u0645\u062e\u062a\u0644\u0641\u0627\u064b \u0628\u0634\u0643\u0644 \u0645\u0639\u062a\u062f \u0628\u0647 \u0625\u062d\u0635\u0627\u0626\u064a\u0627 \u0628\u064a\u0646 \u0627\u0644\u0645\u062c\u0645\u0648\u0639\u0627\u062a \u0627\u0644\u062b\u0644\u0627\u062b \u062d\u064a\u062b \u0643\u0627\u0646\u062a \u0642\u064a\u0645\u062a\u0647 \u0623\u0643\u0628\u0631 \u0641\u064a \u0645\u062c\u0645\u0648\u0639\u062a\u064a \u0645\u0631\u0636\u0649 \u0627\u0644\u0633\u0643\u0631\u064a (\u0623\u0643\u0628\u0631 \u0627\u0644\u0642\u064a\u0645 \u0641\u064a \u0645\u0631\u0636\u0649 \u0627\u0644\u0625\u0642\u0641\u0627\u0631 \u0627\u0644\u0642\u0644\u0628\u064a) \u0645\u0642\u0627\u0631\u0646\u0629 \u0628\u0645\u062c\u0645\u0648\u0639\u0629 \u0627\u0644\u0634\u0648\u0627\u0647\u062f (<em>P<\/em><em> &lt; 0.001<\/em>). <\/span><span style=\"font-family: 'times new roman', times, serif;\">\u0643\u0645\u0627 \u064a\u0639\u0631\u0636 \u0627\u0644\u062c\u062f\u0648\u0644 (2) \u0627\u0644\u0645\u062a\u062b\u0627\u0628\u062a\u0627\u062a \u0627\u0644\u0633\u0631\u064a\u0631\u064a\u0629 \u0648\u0627\u0644\u0645\u062e\u0628\u0631\u064a\u0629 \u0627\u0644\u0645\u062f\u0631\u0648\u0633\u0629 \u0641\u064a \u0645\u062c\u0645\u0648\u0639\u0627\u062a \u0627\u0644\u062f\u0631\u0627\u0633\u0629 \u0627\u0644\u062b\u0644\u0627\u062b\u061b \u0648\u0647\u0648 \u064a\u064f\u0638\u0647\u0631 \u0623\u0646\u0651 \u0627\u0644\u062a\u0628\u0627\u064a\u0646\u0627\u062a \u0628\u064a\u0646 \u0627\u0644\u0645\u062c\u0645\u0648\u0639\u0627\u062a \u0641\u064a \u0642\u064a\u0645 \u0645\u062a\u0648\u0633\u0637\u0627\u062a \u062c\u0645\u064a\u0639 \u0627\u0644\u0645\u062a\u062b\u0627\u0628\u062a\u0627\u062a\u060c \u0628\u0627\u0633\u062a\u062b\u0646\u0627\u0621 \u0646\u0633\u0628\u0629 \u0627\u0644\u0631\u064a\u0632\u0633\u062a\u064a\u0646 \u0625\u0644\u0649 \u0627\u0644\u0623\u0646\u0633\u0648\u0644\u064a\u0646\u060c \u0645\u0639\u062a\u062f\u0651\u064c \u0628\u0647\u0627 \u0625\u062d\u0635\u0627\u0626\u064a\u0627\u064b (\u0642\u064a\u0645\u0629 <em>P<\/em> \u0627\u0644\u0623\u0642\u0644 \u0645\u0646 0.001 \u0641\u064a \u0643\u0644 \u0627\u0644\u062d\u0627\u0644\u0627\u062a). \u0648\u0642\u062f \u0643\u0627\u0646\u062a \u0642\u064a\u0645 \u0645\u062a\u0648\u0633\u0637\u0627\u062a \u0636\u063a\u0637\u00a0 \u0627\u0644\u062f\u0645 \u0648\u0633\u0643\u0631 \u0627\u0644\u0628\u0644\u0627\u0632\u0645\u0627 \u0648\u0627\u0644\u0623\u0646\u0633\u0648\u0644\u064a\u0646 \u0648\u0645\u0642\u0627\u0648\u0645\u0629 \u0627\u0644\u0623\u0646\u0633\u0648\u0644\u064a\u0646 (HOMA-IR) \u0648\u0627\u0644\u062d\u0627\u0644\u0629 \u0627\u0644\u0627\u0644\u062a\u0647\u0627\u0628\u064a\u0629 (CRP) \u0648\u0627\u0644\u0628\u0631\u0648\u0641\u064a\u0644 \u0627\u0644\u0634\u062d\u0645\u064a (\u0628\u0627\u0633\u062a\u062b\u0646\u0627\u0621 HDL-C) \u0648\u0627\u0644\u0631\u064a\u0632\u064a\u0633\u062a\u064a\u0646 \u0648\u0646\u0633\u0628\u062a\u0647 \u0625\u0644\u0649 \u0627\u0644\u0623\u062f\u064a\u0628\u0648\u0646\u0643\u062a\u064a\u0646 \u0647\u064a \u0627\u0644\u0623\u0639\u0644\u0649 \u0641\u064a \u0645\u062c\u0645\u0648\u0639\u0629 \u0627\u0644\u0633\u0643\u0631\u064a\u064a\u0646 \u0627\u0644\u0645\u0635\u0627\u0628\u064a\u0646 \u0628\u0645\u0631\u0636 \u0627\u0644\u0642\u0644\u0628 \u0627\u0644\u0625\u0642\u0641\u0627\u0631\u064a \u062a\u0644\u064a\u0647\u0627 \u0645\u062c\u0645\u0648\u0639\u0629 \u0627\u0644\u0633\u0643\u0631\u064a\u064a\u0646 \u063a\u064a\u0631 \u0627\u0644\u0645\u0635\u0627\u0628\u064a\u0646 \u0628\u0645\u0631\u0636 \u0627\u0644\u0642\u0644\u0628 \u0627\u0644\u0625\u0642\u0641\u0627\u0631\u064a \u0648\u0623\u062e\u064a\u0631\u0627\u064b \u0645\u062c\u0645\u0648\u0639\u0629 \u0627\u0644\u0634\u0648\u0627\u0647\u062f \u0635\u0627\u062d\u0628\u0629 \u0627\u0644\u0642\u064a\u0645 \u0627\u0644\u0623\u062f\u0646\u0649. \u0648\u0642\u062f \u0627\u0646\u0642\u0644\u0628 \u062a\u0631\u062a\u064a\u0628 \u0627\u0644\u0642\u064a\u0645 \u0647\u0630\u0627 \u0645\u0639 \u0642\u064a\u0645 HDL-C \u0648\u0627\u0644\u0623\u062f\u064a\u0628\u0648\u0646\u0643\u062a\u064a\u0646 \u062d\u064a\u062b \u062c\u0627\u0621\u062a \u0627\u0644\u0642\u064a\u0645 \u0627\u0644\u0623\u0639\u0644\u0649 \u0641\u064a \u0645\u062c\u0645\u0648\u0639\u0629 \u0627\u0644\u0634\u0648\u0627\u0647\u062f \u0648\u062a\u0646\u0627\u0642\u0635\u062a \u0645\u0639 \u0648\u062c\u0648\u062f \u0627\u0644\u0646\u0645\u0637 \u0627\u0644\u062b\u0627\u0646\u064a \u0645\u0646 \u0627\u0644\u062f\u0627\u0621 \u0627\u0644\u0633\u0643\u0631\u064a\u060c \u0648\u0643\u0627\u0646\u062a \u0641\u064a \u0623\u062f\u0646\u0627\u0647\u0627 \u0641\u064a \u0645\u062c\u0645\u0648\u0639\u0629 \u0627\u0644\u0633\u0643\u0631\u064a\u064a\u0646 \u0627\u0644\u0645\u0635\u0627\u0628\u064a\u0646 \u0628\u0645\u0631\u0636 \u0627\u0644\u0642\u0644\u0628 \u0627\u0644\u0625\u0642\u0641\u0627\u0631\u064a (\u0642\u064a\u0645\u0629 <em>P<\/em> \u0623\u0642\u0644 \u0645\u0646 0.001 \u0641\u064a \u0643\u0644 \u0627\u0644\u062d\u0627\u0644\u0627\u062a).<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-family: 'times new roman', times, serif;\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-520 \" src=\"https:\/\/pharmjournal.asscph.com\/wp-content\/uploads\/2022\/04\/1-22-e1698856545596-300x198.png\" alt=\"\" width=\"509\" height=\"336\" srcset=\"https:\/\/pharmjournal.asscph.com\/wp-content\/uploads\/2022\/04\/1-22-e1698856545596-300x198.png 300w, https:\/\/pharmjournal.asscph.com\/wp-content\/uploads\/2022\/04\/1-22-e1698856545596-1024x677.png 1024w, https:\/\/pharmjournal.asscph.com\/wp-content\/uploads\/2022\/04\/1-22-e1698856545596-768x508.png 768w, https:\/\/pharmjournal.asscph.com\/wp-content\/uploads\/2022\/04\/1-22-e1698856545596-1536x1016.png 1536w, https:\/\/pharmjournal.asscph.com\/wp-content\/uploads\/2022\/04\/1-22-e1698856545596-2048x1354.png 2048w\" sizes=\"auto, (max-width: 509px) 100vw, 509px\" \/><\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-family: 'times new roman', times, serif;\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-521 \" src=\"https:\/\/pharmjournal.asscph.com\/wp-content\/uploads\/2022\/04\/1-23-e1698856754325-207x300.png\" alt=\"\" width=\"498\" height=\"722\" srcset=\"https:\/\/pharmjournal.asscph.com\/wp-content\/uploads\/2022\/04\/1-23-e1698856754325-207x300.png 207w, https:\/\/pharmjournal.asscph.com\/wp-content\/uploads\/2022\/04\/1-23-e1698856754325-707x1024.png 707w, https:\/\/pharmjournal.asscph.com\/wp-content\/uploads\/2022\/04\/1-23-e1698856754325-768x1112.png 768w, https:\/\/pharmjournal.asscph.com\/wp-content\/uploads\/2022\/04\/1-23-e1698856754325-1060x1536.png 1060w, https:\/\/pharmjournal.asscph.com\/wp-content\/uploads\/2022\/04\/1-23-e1698856754325-1414x2048.png 1414w\" sizes=\"auto, (max-width: 498px) 100vw, 498px\" \/><\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-family: 'times new roman', times, serif;\">\u0648\u0639\u0646\u062f \u0645\u0642\u0627\u0631\u0646\u0629 \u0627\u0644\u0645\u062a\u062b\u0627\u0628\u062a\u0627\u062a \u0627\u0644\u0645\u062f\u0631\u0648\u0633\u0629 \u0628\u064a\u0646 \u0627\u0644\u0630\u0643\u0648\u0631 \u0648\u0627\u0644\u0625\u0646\u0627\u062b \u0636\u0645\u0646 \u0643\u0644 \u0645\u062c\u0645\u0648\u0639\u0629 (\u0627\u0644\u0645\u0639\u0637\u064a\u0627\u062a \u063a\u064a\u0631 \u0645\u0639\u0631\u0648\u0636\u0629 \u0641\u064a \u0627\u0644\u062c\u062f\u0627\u0648\u0644)\u060c \u0627\u0646\u062d\u0635\u0631 \u0627\u0644\u0627\u0639\u062a\u062f\u0627\u062f \u0627\u0644\u0625\u062d\u0635\u0627\u0626\u064a \u0644\u0644\u062a\u0628\u0627\u064a\u0646\u0627\u062a \u0641\u064a \u0645\u062c\u0645\u0648\u0639\u0629 \u0627\u0644\u0634\u0648\u0627\u0647\u062f \u0639\u0644\u0649 \u0627\u0644\u0632\u064a\u0627\u062f\u0629 \u0639\u0646\u062f \u0627\u0644\u0625\u0646\u0627\u062b \u0645\u0642\u0627\u0631\u0646\u0629 \u0628\u0627\u0644\u0630\u0643\u0648\u0631 \u0641\u064a \u0643\u0644 \u0645\u0646 \u0636\u063a\u0637 \u0627\u0644\u062f\u0645 \u0627\u0644\u0625\u0646\u0642\u0628\u0627\u0636\u064a (121.6 \u00b1 5.0 \u0645\u0642\u0627\u0628\u0644 117.7 \u00b1 5.4 \u0645\u0645 \u0632\u0626\u0628\u0642\u064a\u061b <em>P<\/em><em> &lt; 0.05<\/em>) \u0648\u0627\u0644\u0643\u0648\u0644\u064a\u0633\u062a\u0631\u0648\u0644 \u0627\u0644\u0625\u062c\u0645\u0627\u0644\u064a (128.1 \u00b1 14.7 \u0645\u0642\u0627\u0628\u0644 112.4 \u00b1 11.8 \u0645\u0644\u063a\/\u062f\u0644\u061b <em>P<\/em><em> &lt; 0.01<\/em>) \u0648LDL-C (61.8 \u00b1 15.8 \u0645\u0642\u0627\u0628\u0644 40.4 \u00b1 13.0 \u0645\u0644\u063a\/\u062f\u0644\u061b <em>P<\/em><em> &lt; 0.001<\/em>) \u0648non-HDL-C (81.8 \u00b1 17.7 \u0645\u0642\u0627\u0628\u0644 59.6 \u00b1 15.0 \u0645\u0644\u063a\/\u062f\u0644\u061b <em>P<\/em><em> &lt; 0.001<\/em>) \u0648\u0646\u0633\u0628\u0629 \u00a0TC \u0625\u0644\u0649 HDL-C (2.8 \u00b1 0.5 \u0645\u0642\u0627\u0628\u0644 2.2 \u00b1 0.4\u061b <em>P<\/em><em> &lt; 0.001<\/em>) \u0648\u0646\u0633\u0628\u0629 LDL-C \u0625\u0644\u0649 HDL-C (1.4 \u00b1 0.5 \u0645\u0642\u0627\u0628\u0644 0.8 \u00b1 0.3\u061b <em>P<\/em><em> &lt; 0.001<\/em>) \u0648\u0646\u0633\u0628\u0629 non-HDL-C \u0625\u0644\u0649 HDL-C (1.8 \u00b1 0.5 \u0645\u0642\u0627\u0628\u0644 1.2 \u00b1 0.4 \u0645\u0644\u063a\/\u062f\u0644\u061b <em>P<\/em><em> &lt; 0.001<\/em>)\u061b \u0641\u064a \u062d\u064a\u0646 \u0643\u0627\u0646\u062a \u0642\u064a\u0645 HDL-C \u0623\u062e\u0641\u0636 \u0639\u0646\u062f \u0627\u0644\u0625\u0646\u0627\u062b \u0645\u0642\u0627\u0631\u0646\u0629 \u0628\u0627\u0644\u0630\u0643\u0648\u0631 \u0641\u064a \u0647\u0630\u0647 \u0627\u0644\u0645\u062c\u0645\u0648\u0639\u0629 (46.3 \u00b1 5.2 \u0645\u0642\u0627\u0628\u0644 52.8 \u00b1 4.0 \u0645\u0644\u063a\/\u062f\u0644\u061b <em>P<\/em><em> &lt; 0.001<\/em>). \u0623\u0645\u0627 \u0641\u064a \u0645\u062c\u0645\u0648\u0639\u0629 \u0627\u0644\u0633\u0643\u0631\u064a\u064a\u0646 \u063a\u064a\u0631 \u0627\u0644\u0645\u0635\u0627\u0628\u064a\u0646 \u0628\u0645\u0631\u0636 \u0627\u0644\u0642\u0644\u0628 \u0627\u0644\u0625\u0642\u0641\u0627\u0631\u064a \u0641\u0642\u062f \u0627\u0642\u062a\u0635\u0631 \u062a\u0623\u062b\u064a\u0631 \u0627\u0644\u062c\u0646\u0633 \u0639\u0644\u0649 \u0627\u0644\u0627\u0631\u062a\u0641\u0627\u0639 \u0627\u0644\u0645\u0639\u062a\u062f \u0628\u0647 \u0625\u062d\u0635\u0627\u0626\u064a\u0627\u064b \u0639\u0646\u062f \u0627\u0644\u0625\u0646\u0627\u062b \u0645\u0642\u0627\u0628\u0644 \u0627\u0644\u0630\u0643\u0648\u0631 \u0641\u064a \u0642\u064a\u0645 \u0643\u0644 \u0645\u0646 HDL-C (41.6 \u00b1 3.0 \u0645\u0642\u0627\u0628\u0644 37.9 \u00b1 2.9 \u0645\u0644\u063a\/\u062f\u0644\u061b <em>P<\/em><em> &lt; 0.001<\/em>) \u0648\u0646\u0633\u0628\u0629 \u0627\u0644\u0631\u064a\u0632\u0633\u062a\u064a\u0646 \u0639\u0644\u0649 \u0627\u0644\u0623\u0646\u0633\u0648\u0644\u064a\u0646 (1.10 \u00b1 0.47 \u0645\u0642\u0627\u0628\u0644 0.89 \u00b1 0.25\u061b <em>P<\/em><em> &lt; 0.05<\/em>)\u060c \u0648\u0639\u0644\u0649 \u0627\u0644\u0627\u0646\u062e\u0641\u0627\u0636 \u0627\u0644\u0645\u0639\u062a\u062f \u0628\u0647 \u0625\u062d\u0635\u0627\u0626\u064a\u0627\u064b \u0639\u0646\u062f \u0627\u0644\u0625\u0646\u0627\u062b \u0645\u0642\u0627\u0628\u0644 \u0627\u0644\u0630\u0643\u0648\u0631 \u0641\u064a \u0642\u064a\u0645 \u0643\u0644 \u0645\u0646 LDL-C (118.5 \u00b1 14.3 \u0645\u0642\u0627\u0628\u0644 127.1 \u00b1 9.2 \u0645\u0644\u063a\/\u062f\u0644\u061b <em>P<\/em><em> &lt; 0.01<\/em>) \u0648non-HDL-C (148.2 \u00b1 16.4 \u0645\u0642\u0627\u0628\u0644 157.9 \u00b1 13.0 \u0645\u0644\u063a\/\u062f\u0644\u061b <em>P<\/em><em> &lt; 0.05<\/em>) \u0648\u0646\u0633\u0628\u0629 \u00a0TC \u0625\u0644\u0649 HDL-C (4.6 \u00b1 0.6 \u0645\u0642\u0627\u0628\u0644 5.2 \u00b1 0.7\u061b <em>P<\/em><em> &lt; 0.01<\/em>) \u0648\u0646\u0633\u0628\u0629 LDL-C \u0625\u0644\u0649 HDL-C (2.9 \u00b1 0.5 \u0645\u0642\u0627\u0628\u0644 3.4 \u00b1 0.5\u061b <em>P<\/em><em> &lt; 0.001<\/em>) \u0648\u0646\u0633\u0628\u0629 non-HDL-C \u0625\u0644\u0649 HDL-C (3.6 \u00b1 0.6 \u0645\u0642\u0627\u0628\u0644 4.2 \u00b1 0.7\u061b <em>P<\/em><em> &lt; 0.05<\/em>). \u0648\u0623\u062e\u064a\u0631\u0627\u064b\u060c \u0641\u0642\u062f \u0643\u0627\u0646 \u0627\u0644\u0627\u0639\u062a\u062f\u0627\u062f \u0627\u0644\u0625\u062d\u0635\u0627\u0626\u064a \u0644\u0644\u0641\u0631\u0648\u0642 \u0628\u064a\u0646 \u0627\u0644\u0645\u062a\u062b\u0627\u0628\u062a\u0627\u062a \u0641\u064a \u0645\u062c\u0645\u0648\u0639\u0629 \u0627\u0644\u0633\u0643\u0631\u064a\u064a\u0646 \u0627\u0644\u0645\u0635\u0627\u0628\u064a\u0646 \u0628\u0645\u0631\u0636 \u0627\u0644\u0642\u0644\u0628 \u0627\u0644\u0625\u0642\u0641\u0627\u0631\u064a \u0645\u0642\u062a\u0635\u0631\u0627\u064b \u0639\u0644\u0649 \u0646\u0642\u0635 \u0627\u0644\u0645\u062a\u062b\u0627\u0628\u062a\u0627\u062a \u0627\u0644\u062a\u0627\u0644\u064a\u0629 \u0639\u0646\u062f \u0627\u0644\u0625\u0646\u0627\u062b \u0645\u0642\u0627\u0628\u0644 \u0627\u0644\u0630\u0643\u0648\u0631: \u0627\u0644\u0643\u0648\u0644\u064a\u0633\u062a\u0631\u0648\u0644 \u0627\u0644\u0625\u062c\u0645\u0627\u0644\u064a (227.5 \u00b1 27.9 \u0645\u0642\u0627\u0628\u0644 244.0 \u00b1 24.3 \u0645\u0644\u063a\/\u062f\u0644) \u0648LDL-C (158.2 \u00b1 27.6 \u0645\u0642\u0627\u0628\u0644 175.0 \u00b1 22.3 \u0645\u0644\u063a\/\u062f\u0644) \u0648non-HDL-C (191.6 \u00b1 32.3 \u0645\u0642\u0627\u0628\u0644 207.7 \u00b1 26.4 \u0645\u0644\u063a\/\u062f\u0644)\u060c \u0648\u0643\u0627\u0646\u062a \u0642\u064a\u0645\u0629 <em>P<\/em><em> &lt; 0.05<\/em> \u0641\u064a \u0627\u0644\u062d\u0627\u0644\u0627\u062a \u0627\u0644\u062b\u0644\u0627\u062b. <\/span><span style=\"font-family: 'times new roman', times, serif;\">\u0648\u0641\u064a\u0645\u0627 \u064a\u062a\u0639\u0644\u0642 \u0628\u0646\u0648\u0639 \u0645\u0639\u0627\u0644\u062c\u0629 \u0627\u0644\u0633\u0643\u0631\u064a\u060c \u0643\u0627\u0646 \u0647\u0646\u0627\u0643 33 \u0645\u0631\u064a\u0636\u0627\u064b \u064a\u062a\u0644\u0642\u0648\u0646 \u0627\u0644\u0639\u0644\u0627\u062c\u0627\u062a \u0627\u0644\u0641\u0645\u0648\u064a\u0629 \u0627\u0644\u062e\u0627\u0641\u0636\u0629 \u0644\u0633\u0643\u0631 \u0627\u0644\u062f\u0645 \u0645\u0642\u0627\u0628\u0644 27 \u0645\u0631\u064a\u0636\u0627\u064b \u0639\u0644\u0649 \u0627\u0644\u062d\u0645\u064a\u0629 \u0627\u0644\u063a\u0630\u0627\u0626\u064a\u0629 \u0641\u0642\u0637 \u0641\u064a \u0645\u062c\u0645\u0648\u0639\u0629 \u0627\u0644\u0633\u0643\u0631\u064a\u064a\u0646 \u062f\u0648\u0646 \u0645\u0631\u0636 \u0627\u0644\u0642\u0644\u0628 \u0627\u0644\u0625\u0642\u0641\u0627\u0631\u064a. \u0644\u0645 \u064a\u064f\u0638\u0647\u0631 \u0627\u062e\u062a\u0628\u0627\u0631 t \u0627\u0639\u062a\u062f\u0627\u062f\u0627\u064b \u0625\u062d\u0635\u0627\u0626\u064a\u0627\u064b \u0644\u0644\u062a\u0628\u0627\u064a\u0646 \u0641\u064a \u0627\u0644\u0645\u062a\u062b\u0627\u0628\u062a\u0627\u062a \u0627\u0644\u0645\u062f\u0631\u0648\u0633\u0629 \u0628\u064a\u0646 \u0647\u0627\u062a\u064a\u0646 \u0627\u0644\u0645\u062c\u0645\u0648\u0639\u062a\u064a\u0646 \u0627\u0644\u0641\u0631\u0639\u064a\u062a\u064a\u0646 \u0625\u0644\u0627 \u0641\u064a \u062d\u0627\u0644\u0629 \u0646\u0633\u0628\u0629 \u0627\u0644\u0631\u064a\u0632\u0633\u062a\u064a\u0646 \u0625\u0644\u0649 \u0627\u0644\u0623\u0646\u0633\u0648\u0644\u064a\u0646 (0.86 \u00b1 0.26 \u0645\u0639 \u0627\u0644\u0639\u0644\u0627\u062c\u0627\u062a \u0627\u0644\u0641\u0645\u0648\u064a\u0629 \u0645\u0642\u0627\u0628\u0644 1.14 \u00b1 0.46 \u0645\u0639 \u0627\u0644\u062d\u0645\u064a\u0629 \u0627\u0644\u063a\u0630\u0627\u0626\u064a\u0629\u061b <em>P<\/em><em> &lt; 0.01<\/em>). \u0623\u0645\u0627 \u0641\u064a \u0645\u062c\u0645\u0648\u0639\u0629 \u0627\u0644\u0633\u0643\u0631\u064a\u064a\u0646 \u0627\u0644\u0645\u0635\u0627\u0628\u064a\u0646 \u0628\u0645\u0631\u0636 \u0627\u0644\u0642\u0644\u0628 \u0627\u0644\u0625\u0642\u0641\u0627\u0631\u064a (59 \u0645\u0631\u064a\u0636\u0627\u064b: 20 \u0645\u0631\u064a\u0636\u0627\u064b \u0639\u0644\u0649 \u0627\u0644\u062d\u0645\u064a\u0629 \u0627\u0644\u063a\u0630\u0627\u0626\u064a\u0629 \u064827 \u0645\u0631\u064a\u0636\u0627\u064b \u0639\u0644\u0649 \u0627\u0644\u0639\u0644\u0627\u062c\u0627\u062a \u0627\u0644\u0641\u0645\u0648\u064a\u0629 \u0627\u0644\u062e\u0627\u0641\u0636\u0629 \u0644\u0633\u0643\u0631 \u0627\u0644\u062f\u0645 \u064812 \u0645\u0631\u064a\u0636\u0627\u064b \u0639\u0644\u0649 \u0627\u0644\u0623\u0646\u0633\u0648\u0644\u064a\u0646) \u0648\u0641\u064a \u0645\u062c\u0645\u0648\u0639\u0629 \u0627\u0644\u0633\u0643\u0631\u064a\u064a\u0646 \u062c\u0645\u064a\u0639\u0647\u0645 (119 \u0645\u0631\u064a\u0636\u0627\u064b: 47 \u0645\u0631\u064a\u0636\u0627\u064b \u0639\u0644\u0649 \u0627\u0644\u062d\u0645\u064a\u0629 \u0627\u0644\u063a\u0630\u0627\u0626\u064a\u0629 \u064860 \u0645\u0631\u064a\u0636\u0627\u064b \u0639\u0644\u0649 \u0627\u0644\u0639\u0644\u0627\u062c\u0627\u062a \u0627\u0644\u0641\u0645\u0648\u064a\u0629 \u0627\u0644\u062e\u0627\u0641\u0636\u0629 \u0644\u0633\u0643\u0631 \u0627\u0644\u062f\u0645 \u064812 \u0645\u0631\u064a\u0636\u0627\u064b \u0639\u0644\u0649 \u0627\u0644\u0623\u0646\u0633\u0648\u0644\u064a\u0646) \u0641\u0644\u0645 \u064a\u0638\u0647\u0631 \u0627\u062e\u062a\u0628\u0627\u0631 \u0627\u0644\u0623\u0646\u0648\u0641\u0627 \u0623\u064a \u062a\u0623\u062b\u064a\u0631 \u0645\u0639\u062a\u062f \u0628\u0647 \u0625\u062d\u0635\u0627\u0626\u064a\u0627 \u0639\u0644\u0649 \u0627\u0644\u062a\u0628\u0627\u064a\u0646\u0627\u062a \u0641\u064a \u0627\u0644\u0645\u062a\u062b\u0627\u0628\u062a\u0627\u062a \u0627\u0644\u0645\u062f\u0631\u0648\u0633\u0629 \u0648\u0641\u0642 \u0646\u0645\u0637 \u0627\u0644\u0639\u0644\u0627\u062c. <\/span><span style=\"font-family: 'times new roman', times, serif;\">\u064a\u0639\u0631\u0636 \u0627\u0644\u062c\u062f\u0648\u0644 (3) \u0646\u062a\u0627\u0626\u062c \u062f\u0631\u0627\u0633\u0629 \u0627\u0644\u0627\u0631\u062a\u0628\u0627\u0637\u0627\u062a [\u0642\u064a\u0645 \u0645\u0639\u0627\u0645\u0644 \u0627\u0644\u0627\u0631\u062a\u0628\u0627\u0637 \u0648\u0641\u0642 \u0628\u064a\u0631\u0633\u0648\u0646 (r) \u0645\u0639 \u0627\u0644\u0627\u0639\u062a\u062f\u0627\u062f \u0627\u0644\u0625\u062d\u0635\u0627\u0626\u064a (\u0642\u064a\u0645 <em>P<\/em>)] \u0628\u064a\u0646 \u0643\u0644 \u0645\u0646 \u0627\u0644\u0623\u062f\u064a\u0628\u0648\u0646\u0643\u062a\u064a\u0646 \u0648\u0627\u0644\u0631\u064a\u0632\u064a\u0633\u062a\u064a\u0646 \u0648\u0646\u0633\u0628\u062a\u0647 \u0625\u0644\u0649 \u0643\u0644 \u0645\u0646 \u0627\u0644\u0623\u0646\u0633\u0648\u0644\u064a\u0646 \u0648\u0627\u0644\u0631\u064a\u0632\u064a\u0633\u062a\u064a\u0646 \u0645\u0646 \u062c\u0647\u0629\u060c \u0648\u0628\u064a\u0646 \u0645\u062e\u062a\u0644\u0641 \u0627\u0644\u0645\u062a\u062b\u0627\u0628\u062a\u0627\u062a \u0627\u0644\u0645\u062a\u0647\u0645\u0629 \u0639\u0644\u0649 \u0623\u0646\u0647\u0627 \u0639\u0648\u0627\u0645\u0644 \u0627\u062e\u062a\u0637\u0627\u0631 \u0644\u0644\u0645\u0631\u0636 \u0627\u0644\u0642\u0644\u0628\u064a \u0627\u0644\u0625\u0642\u0641\u0627\u0631\u064a \u0641\u064a \u0645\u062c\u0645\u0648\u0639\u0627\u062a \u0627\u0644\u062f\u0631\u0627\u0633\u0629 \u0627\u0644\u062b\u0644\u0627\u062b. \u0648\u0643\u0645\u0627 \u064a\u0638\u0647\u0631 \u0641\u064a \u0627\u0644\u062c\u062f\u0648\u0644\u060c \u0644\u0645 \u064a\u0643\u0646 \u0647\u0646\u0627\u0643 \u0623\u064a \u0627\u0631\u062a\u0628\u0627\u0637 \u0645\u0639\u062a\u062f \u0628\u0647 \u0625\u062d\u0635\u0627\u0626\u064a\u0627\u064b \u0644\u0623\u064a \u0645\u0646 \u0642\u064a\u0645 \u0647\u0630\u0647 \u0627\u0644\u0647\u0631\u0645\u0648\u0646\u0627\u062a \u0648\u0627\u0644\u0646\u0633\u0628 \u0645\u0639 \u0627\u0644\u0639\u0645\u0631 \u0641\u064a \u0627\u0644\u0645\u062c\u0645\u0648\u0639\u0627\u062a \u0627\u0644\u062b\u0644\u0627\u062b \u0627\u0644\u0645\u062f\u0631\u0648\u0633\u0629. \u0643\u0645\u0627 \u064a\u0648\u0636\u062d \u0627\u0644\u062c\u062f\u0648\u0644 (3) \u0623\u0646\u0651 \u0642\u064a\u0645 \u0627\u0644\u0623\u062f\u064a\u0628\u0648\u0646\u0643\u062a\u064a\u0646 \u0627\u0631\u062a\u0628\u0637\u062a \u0627\u0631\u062a\u0628\u0627\u0637\u0627\u064b \u0625\u064a\u062c\u0627\u0628\u064a\u0627\u064b \u0645\u0639\u062a\u062f\u0627\u064b \u0628\u0647 \u0625\u062d\u0635\u0627\u0626\u064a\u0627\u064b (<em>P<\/em><em> \u0623\u0642\u0644 \u0645\u0646 0.05<\/em> <em>\u0623\u0648 0.01<\/em>) \u0641\u064a \u0627\u0644\u0645\u062c\u0645\u0648\u0639\u0627\u062a \u0627\u0644\u062b\u0644\u0627\u062b \u0645\u0639 \u0642\u064a\u0645 HDL-C \u0630\u0627\u062a \u0627\u0644\u062a\u0623\u062b\u064a\u0631 \u0627\u0644\u0648\u0627\u0642\u064a \u0645\u0646 \u0645\u0631\u0636 \u0627\u0644\u0642\u0644\u0628 \u0627\u0644\u0625\u0642\u0641\u0627\u0631\u064a\u061b \u0641\u064a \u062d\u064a\u0646 \u0643\u0627\u0646 \u0627\u0644\u0627\u0631\u062a\u0628\u0627\u0637 \u0633\u0644\u0628\u064a\u0627\u064b \u0645\u0639 \u0639\u0648\u0627\u0645\u0644 \u0627\u0644\u0627\u062e\u062a\u0637\u0627\u0631 \u0627\u0644\u0642\u0644\u0628\u064a\u0629 \u0627\u0644\u0645\u062e\u062a\u0644\u0641\u0629 \u062c\u0645\u064a\u0639\u0647\u0627 [\u0636\u063a\u0637 \u0627\u0644\u062f\u0645 \u0648\u0627\u0644\u0628\u062f\u0627\u0646\u0629 (BMI) \u0648\u0627\u0644\u0633\u0643\u0631 \u0627\u0644\u0635\u064a\u0627\u0645\u064a \u0648\u0627\u0644\u0623\u0646\u0633\u0648\u0644\u064a\u0646 \u0627\u0644\u0635\u064a\u0627\u0645\u064a \u0648\u0645\u0642\u0627\u0648\u0645\u0629 \u0627\u0644\u0623\u0646\u0633\u0648\u0644\u064a\u0646 (HOMA-IR) \u0648\u0627\u0644\u062d\u0627\u0644\u0629 \u0627\u0644\u0627\u0644\u062a\u0647\u0627\u0628\u064a\u0629 (CRP) \u0648TAG \u0648TC \u0648LDL-C \u0648non-HDL-C \u0648\u0646\u0633\u0628 \u0627\u0644\u0645\u062a\u062b\u0627\u0628\u062a\u0627\u062a \u0627\u0644\u062b\u0644\u0627\u062b \u0627\u0644\u0623\u062e\u064a\u0631\u0629 \u0625\u0644\u0649 HDL-C] \u0641\u064a \u0645\u062c\u0645\u0648\u0639\u062a\u064a \u0627\u0644\u0634\u0648\u0627\u0647\u062f \u0648\u0627\u0644\u0633\u0643\u0631\u064a\u064a\u0646 \u0627\u0644\u0645\u0635\u0627\u0628\u064a\u0646 \u0628\u0645\u0631\u0636 \u0627\u0644\u0625\u0642\u0641\u0627\u0631 \u0627\u0644\u0642\u0644\u0628\u064a (<em>P<\/em><em> \u0623\u0642\u0644 \u0645\u0646 0.01<\/em> \u0641\u064a \u0643\u0644 \u0627\u0644\u062d\u0627\u0644\u0627\u062a). \u0623\u0645\u0627 \u0641\u064a \u0645\u062c\u0645\u0648\u0639\u0629 \u0627\u0644\u0633\u0643\u0631\u064a\u064a\u0646 \u063a\u064a\u0631 \u0627\u0644\u0645\u0635\u0627\u0628\u064a\u0646 \u0628\u0645\u0631\u0636 \u0627\u0644\u0625\u0642\u0641\u0627\u0631 \u0627\u0644\u0642\u0644\u0628\u064a \u0641\u0642\u062f \u0627\u0642\u062a\u0635\u0631 \u0627\u0644\u0627\u0639\u062a\u062f\u0627\u062f \u0627\u0644\u0625\u062d\u0635\u0627\u0626\u064a \u0644\u0644\u0627\u0631\u062a\u0628\u0627\u0637 \u0627\u0644\u0633\u0644\u0628\u064a \u0644\u0644\u0623\u062f\u064a\u0628\u0648\u0646\u0643\u062a\u064a\u0646 \u0645\u0639 \u0639\u0648\u0627\u0645\u0644 \u0627\u0644\u0627\u062e\u062a\u0637\u0627\u0631 \u0627\u0644\u0642\u0644\u0628\u064a\u0629 \u0639\u0644\u0649 \u0642\u064a\u0645 BMI (<em>P<\/em><em> \u0623\u0642\u0644 \u0645\u0646 0.01<\/em>) \u0648TC \u0648LDL-C \u0648non-HDL-C (<em>P<\/em><em> \u0623\u0642\u0644 \u0645\u0646 0.05<\/em> \u0641\u064a \u0643\u0644 \u0627\u0644\u062d\u0627\u0644\u0627\u062a) \u0648\u0646\u0633\u0628 \u0627\u0644\u0645\u062a\u062b\u0627\u0628\u062a\u0627\u062a \u0627\u0644\u062b\u0644\u0627\u062b \u0627\u0644\u0623\u062e\u064a\u0631\u0629 \u0625\u0644\u0649 HDL-C (<em>P<\/em><em> \u0623\u0642\u0644 \u0645\u0646 0.01<\/em> \u0641\u064a \u0643\u0644 \u0627\u0644\u062d\u0627\u0644\u0627\u062a) (\u0627\u0644\u062c\u062f\u0648\u0644 3). <\/span><span style=\"font-family: 'times new roman', times, serif;\">\u0623\u0645\u0627 \u0642\u064a\u0645 \u0627\u0644\u0631\u064a\u0632\u064a\u0633\u062a\u064a\u0646 \u0641\u0642\u062f \u0627\u0631\u062a\u0628\u0637\u062a\u060c \u0648\u0641\u064a \u0627\u0644\u0645\u062c\u0645\u0648\u0639\u0627\u062a \u0627\u0644\u062b\u0644\u0627\u062b\u060c \u0627\u0631\u062a\u0628\u0627\u0637\u0627\u064b \u0633\u0644\u0628\u064a\u0627\u064b \u0645\u0639\u062a\u062f\u0627\u064b \u0628\u0647 \u0625\u062d\u0635\u0627\u0626\u064a\u0627\u064b \u0645\u0639 \u0642\u064a\u0645 HDL-C (<em>P<\/em><em> \u0623\u0642\u0644 \u0645\u0646 0.05<\/em> \u0641\u064a \u0645\u062c\u0645\u0648\u0639\u0629 \u0627\u0644\u0634\u0648\u0627\u0647\u062f \u0648<em> \u0623\u0642\u0644 \u0645\u0646 0.01<\/em> \u0641\u064a \u0645\u062c\u0645\u0648\u0639\u062a\u064a \u0627\u0644\u0633\u0643\u0631\u064a)\u060c \u0648\u0627\u0631\u062a\u0628\u0627\u0637\u0627\u064b \u0625\u064a\u062c\u0627\u0628\u064a\u0627\u064b \u0645\u0639 \u0639\u0648\u0627\u0645\u0644 \u0627\u0644\u0627\u062e\u062a\u0637\u0627\u0631 \u0627\u0644\u0642\u0644\u0628\u064a\u0629 \u0627\u0644\u0645\u062e\u062a\u0644\u0641\u0629 \u062c\u0645\u064a\u0639\u0647\u0627 (<em>P<\/em><em> \u0623\u0642\u0644 \u0645\u0646 0.01<\/em> \u0641\u064a \u0627\u0644\u062d\u0627\u0644\u0627\u062a \u062c\u0645\u064a\u0639\u0647\u0627 \u0639\u062f\u0627 \u0627\u0644\u0636\u063a\u0637 \u0627\u0644\u0627\u0646\u0642\u0628\u0627\u0636\u064a \u0641\u064a \u0645\u062c\u0645\u0648\u0639\u0629 \u0627\u0644\u0633\u0643\u0631\u064a\u064a\u0646 \u0645\u0639 \u0627\u0644\u0645\u0631\u0636 \u0627\u0644\u0642\u0644\u0628\u064a \u0627\u0644\u0625\u0642\u0641\u0627\u0631\u064a \u0648\u0627\u0644\u0623\u0646\u0633\u0648\u0644\u064a\u0646 \u0648\u0646\u0633\u0628 \u0627\u0644\u0634\u062d\u0645\u064a\u0627\u062a \u0627\u0644\u062b\u0644\u0627\u062b \u0641\u064a \u0645\u062c\u0645\u0648\u0639\u0629 \u0627\u0644\u0634\u0648\u0627\u0647\u062f \u062d\u064a\u062b \u0643\u0627\u0646\u062a <em>P<\/em><em> \u0623\u0642\u0644 \u0645\u0646 0.05<\/em>) (\u0627\u0644\u062c\u062f\u0648\u0644 3). <\/span><span style=\"font-family: 'times new roman', times, serif;\">\u0648\u0627\u0642\u062a\u0635\u0631\u062a \u0627\u0644\u0627\u0631\u062a\u0628\u0627\u0637\u0627\u062a \u0627\u0644\u0645\u0647\u0645\u0629 \u0625\u062d\u0635\u0627\u0626\u064a\u0627\u064b \u0644\u0642\u064a\u0645 \u0646\u0633\u0628\u0629 \u0627\u0644\u0631\u064a\u0632\u064a\u0633\u062a\u064a\u0646 \u0639\u0644\u0649 \u0627\u0644\u0623\u0646\u0633\u0648\u0644\u064a\u0646 \u0645\u0639 \u0627\u0644\u0645\u062a\u062b\u0627\u0628\u062a\u0627\u062a \u0627\u0644\u0623\u062e\u0631\u0649 \u0641\u064a \u0645\u062c\u0645\u0648\u0639\u0629 \u0627\u0644\u0634\u0648\u0627\u0647\u062f \u0639\u0644\u0649 \u0627\u0644\u0627\u0631\u062a\u0628\u0627\u0637 \u0627\u0644\u0625\u064a\u062c\u0627\u0628\u064a \u0645\u0639 CRP (<em>P<\/em><em> \u0623\u0642\u0644 \u0645\u0646 0.05<\/em>)\u060c \u0648\u0641\u064a \u0645\u062c\u0645\u0648\u0639\u0629 \u0627\u0644\u0633\u0643\u0631\u064a\u064a\u0646 \u062f\u0648\u0646 \u0627\u0644\u0645\u0631\u0636 \u0627\u0644\u0642\u0644\u0628\u064a \u0627\u0644\u0625\u0642\u0641\u0627\u0631\u064a \u0639\u0644\u0649 \u0627\u0644\u0627\u0631\u062a\u0628\u0627\u0637 \u0627\u0644\u0633\u0644\u0628\u064a \u0645\u0639 \u0627\u0644\u0633\u0643\u0631 \u0627\u0644\u0635\u064a\u0627\u0645\u064a \u0648\u0627\u0644\u0623\u0646\u0633\u0648\u0644\u064a\u0646 \u0627\u0644\u0635\u064a\u0627\u0645\u064a \u0648HOMA-IR \u0648CRP (<em>P<\/em><em> \u0623\u0642\u0644 \u0645\u0646 0.01<\/em> \u0641\u064a \u0627\u0644\u062d\u0627\u0644\u0627\u062a \u062c\u0645\u064a\u0639\u0647\u0627) (\u0627\u0644\u062c\u062f\u0648\u0644 3). \u0623\u0645\u0627 \u0641\u064a \u0645\u062c\u0645\u0648\u0639\u0629 \u0627\u0644\u0633\u0643\u0631\u064a\u064a\u0646 \u0645\u0639 \u0627\u0644\u0645\u0631\u0636 \u0627\u0644\u0642\u0644\u0628\u064a \u0627\u0644\u0625\u0642\u0641\u0627\u0631\u064a \u0641\u0643\u0627\u0646 \u0646\u0645\u0637 \u0627\u0631\u062a\u0628\u0627\u0637\u0627\u062a \u0646\u0633\u0628\u0629 \u0627\u0644\u0631\u064a\u0632\u064a\u0633\u062a\u064a\u0646 \u0639\u0644\u0649 \u0627\u0644\u0623\u0646\u0633\u0648\u0644\u064a\u0646 \u0645\u0639 \u0627\u0644\u0645\u062a\u062b\u0627\u0628\u062a\u0627\u062a \u0627\u0644\u0623\u062e\u0631\u0649 \u0645\u0634\u0627\u0628\u0647\u0627\u064b \u062a\u0642\u0631\u064a\u0628\u0627\u064b \u0644\u0646\u0645\u0637 \u0627\u0631\u062a\u0628\u0627\u0637\u0627\u062a \u0627\u0644\u0623\u062f\u064a\u0628\u0648\u0646\u0643\u062a\u064a\u0646 (\u0627\u0644\u062c\u062f\u0648\u0644 3) \u062d\u064a\u062b \u0627\u0631\u062a\u0628\u0637\u062a \u0647\u0630\u0647 \u0627\u0644\u0646\u0633\u0628\u0629 \u0625\u064a\u062c\u0627\u0628\u064a\u0627\u064b \u0645\u0639 HDL-C \u0648\u0633\u0644\u0628\u064a\u0627\u064b \u0645\u0639 \u0636\u063a\u0637 \u0627\u0644\u062f\u0645 \u0627\u0644\u0627\u0646\u0642\u0628\u0627\u0636\u064a \u0648CRP \u0648TAG \u0648TC \u0648BMI \u0648\u0627\u0644\u0633\u0643\u0631 \u0627\u0644\u0635\u064a\u0627\u0645\u064a \u0648\u0627\u0644\u0623\u0646\u0633\u0648\u0644\u064a\u0646 \u0627\u0644\u0635\u064a\u0627\u0645\u064a \u0648HOMA-IR \u0648LDL-C \u0648non-HDL-C\u060c \u0648\u0646\u0633\u0628\u0629 \u0643\u0644 \u0645\u0646 TC \u0648LDL-C \u0648non-HDL-C \u0625\u0644\u0649 HDL-C (\u0627\u0644\u062c\u062f\u0648\u0644 3). <\/span><span style=\"font-family: 'times new roman', times, serif;\">\u0648\u0627\u0631\u062a\u0628\u0637\u062a \u0642\u064a\u0645 \u0646\u0633\u0628\u0629 \u0627\u0644\u0631\u064a\u0632\u064a\u0633\u062a\u064a\u0646 \u0625\u0644\u0649 \u0627\u0644\u0623\u062f\u064a\u0628\u0648\u0646\u0643\u062a\u064a\u0646 \u0627\u0631\u062a\u0628\u0627\u0637\u0627\u064b \u0633\u0644\u0628\u064a\u0627\u064b \u0645\u0639\u062a\u062f\u0627\u064b \u0628\u0647 \u0625\u062d\u0635\u0627\u0626\u064a\u0627\u064b \u0641\u064a \u0627\u0644\u0645\u062c\u0645\u0648\u0639\u0627\u062a \u0627\u0644\u062b\u0644\u0627\u062b \u0645\u0639 \u0642\u064a\u0645 HDL-C \u0630\u0627\u062a \u0627\u0644\u062a\u0623\u062b\u064a\u0631 \u0627\u0644\u0648\u0627\u0642\u064a \u0645\u0646 \u0645\u0631\u0636 \u0627\u0644\u0642\u0644\u0628 \u0627\u0644\u0625\u0642\u0641\u0627\u0631\u064a (<em>P<\/em><em> \u0623\u0642\u0644 \u0645\u0646 0.01<\/em>)\u061b \u0641\u064a \u062d\u064a\u0646 \u0643\u0627\u0646 \u0627\u0631\u062a\u0628\u0627\u0637\u0647\u0627 \u0625\u064a\u062c\u0627\u0628\u064a\u0627\u064b \u0645\u0639 \u0639\u0648\u0627\u0645\u0644 \u0627\u0644\u0627\u062e\u062a\u0637\u0627\u0631 \u0627\u0644\u0642\u0644\u0628\u064a\u0629 \u0627\u0644\u0645\u062e\u062a\u0644\u0641\u0629 \u062c\u0645\u064a\u0639\u0647\u0627 (\u0636\u063a\u0637 \u0627\u0644\u062f\u0645 \u0648BMI \u0648\u0627\u0644\u0633\u0643\u0631 \u0627\u0644\u0635\u064a\u0627\u0645\u064a \u0648\u0627\u0644\u0623\u0646\u0633\u0648\u0644\u064a\u0646 \u0627\u0644\u0635\u064a\u0627\u0645\u064a \u0648HOMA-IR \u0648CRP \u0648TAG \u0648TC \u0648LDL-C \u0648non-HDL-C \u0648\u0646\u0633\u0628 \u0627\u0644\u0645\u062a\u062b\u0627\u0628\u062a\u0627\u062a \u0627\u0644\u062b\u0644\u0627\u062b \u0627\u0644\u0623\u062e\u064a\u0631\u0629 \u0625\u0644\u0649 HDL-C) \u0641\u064a \u0627\u0644\u0645\u062c\u0645\u0648\u0639\u0627\u062a \u0627\u0644\u062b\u0644\u0627\u062b [<em>P<\/em><em> \u0623\u0642\u0644 \u0645\u0646 0.01<\/em> \u0641\u064a \u0627\u0644\u062d\u0627\u0644\u0627\u062a \u0643\u0644\u0647\u0627 \u0639\u062f\u0627 \u0636\u063a\u0637 \u0627\u0644\u062f\u0645 \u0627\u0644\u0627\u0646\u0642\u0628\u0627\u0636\u064a \u0648TAG \u0641\u064a \u0645\u062c\u0645\u0648\u0639\u0629 \u0627\u0644\u0633\u0643\u0631\u064a\u064a\u0646 \u063a\u064a\u0631 \u0627\u0644\u0645\u0635\u0627\u0628\u064a\u0646 \u0628\u0645\u0631\u0636 \u0627\u0644\u0625\u0642\u0641\u0627\u0631 \u0627\u0644\u0642\u0644\u0628\u064a (<em>P<\/em><em> \u0623\u0642\u0644 \u0645\u0646 0.05<\/em>)] (\u0627\u0644\u062c\u062f\u0648\u0644 3). <\/span><span style=\"font-family: 'times new roman', times, serif;\">\u0646\u062a\u0627\u0626\u062c \u062a\u062d\u0644\u064a\u0644 \u0627\u0644\u062a\u062d\u0648\u0641 \u0627\u0644\u0644\u0648\u062c\u064a\u0633\u062a\u064a (\u0627\u0644\u0625\u0645\u062f\u0627\u062f\u064a) \u0627\u0644\u062b\u0646\u0627\u0626\u064a logistic binary regression \u0645\u0639\u0631\u0648\u0636\u0629 \u0641\u064a \u0627\u0644\u062c\u062f\u0648\u0644 (4) \u0648\u062a\u0638\u0647\u0631 \u0646\u0633\u0628\u0629 \u0627\u0644\u0623\u0631\u062c\u062d\u064a\u0629 \u0627\u0644\u0623\u0639\u0644\u0649 \u0644\u0646\u0633\u0628\u0629 \u0627\u0644\u0631\u064a\u0632\u0633\u062a\u064a\u0646 \u0625\u0644\u0649 \u0627\u0644\u0623\u062f\u064a\u0628\u0648\u0646\u0643\u062a\u064a\u0646 (1.67 = OR) \u062b\u0645 \u0627\u0644\u0631\u064a\u0632\u064a\u0633\u062a\u064a\u0646 (1.35 = OR) \u062b\u0645 \u0627\u0644\u0623\u062f\u064a\u0628\u0648\u0646\u0643\u062a\u064a\u0646 (0.74 = OR) (<em>P<\/em><em> \u0623\u0642\u0644 \u0645\u0646 0.001<\/em> \u0641\u064a \u0627\u0644\u062d\u0627\u0644\u0627\u062a \u0627\u0644\u062b\u0644\u0627\u062b) \u062b\u0645 \u0646\u0633\u0628\u0629 \u0627\u0644\u0631\u064a\u0632\u0633\u062a\u064a\u0646 \u0625\u0644\u0649 \u0627\u0644\u0623\u0646\u0633\u0648\u0644\u064a\u0646 (0.34 = OR\u061b <em>0.059 = P<\/em>) (\u0627\u0644\u062c\u062f\u0648\u0644 4). \u0648\u064a\u0639\u0631\u0636 \u0627\u0644\u0634\u0643\u0644 (1) \u0646\u062a\u0627\u0626\u062c \u0627\u062e\u062a\u0628\u0627\u0631 \u0645\u0646\u062d\u0646\u0649 \u062e\u0627\u0635\u064a\u0629 \u062a\u0634\u063a\u064a\u0644 \u0627\u0644\u0645\u0633\u062a\u0642\u0628\u0644 ROC \u0648\u0625\u062d\u0635\u0627\u0626\u064a\u0627\u062a \u0627\u0644\u0645\u0633\u0627\u062d\u0629 \u062a\u062d\u062a\u0647 AUC\u060c \u0648\u064a\u064f\u0638\u0647\u0631 \u0627\u0644\u0642\u062f\u0631\u0629 \u0627\u0644\u062a\u0646\u0628\u0624\u064a\u0629 \u0627\u0644\u0625\u064a\u062c\u0627\u0628\u064a\u0629 \u0644\u0644\u0631\u064a\u0632\u064a\u0633\u062a\u064a\u0646 (0.812 = AUC) \u0648\u0646\u0633\u0628\u0629 \u0627\u0644\u0631\u064a\u0632\u064a\u0633\u062a\u064a\u0646 \u0639\u0644\u0649 \u0627\u0644\u0623\u062f\u064a\u0628\u0648\u0646\u0643\u062a\u064a\u0646 (0.850 = AUC) \u0648\u0627\u0644\u0642\u062f\u0631\u0629 \u0627\u0644\u062a\u0646\u0628\u0624\u064a\u0629 \u0627\u0644\u0648\u0642\u0627\u0626\u064a\u0629 \u0644\u0644\u0623\u062f\u064a\u0628\u0648\u0646\u0643\u062a\u064a\u0646 (0.812 = AUC) (<em>0.001 &gt; P<\/em> \u0641\u064a \u0627\u0644\u062d\u0627\u0644\u0627\u062a \u0643\u0644\u0647\u0627). \u0623\u0645\u0627 \u0646\u0633\u0628\u0629 \u0627\u0644\u0631\u064a\u0632\u064a\u0633\u062a\u064a\u0646 \u0625\u0644\u0649 \u0627\u0644\u0623\u0646\u0633\u0648\u0644\u064a\u0646 \u0641\u0644\u0645 \u062a\u0639\u0637 \u0642\u064a\u0645\u0629 \u0630\u0627\u062a \u0627\u0639\u062a\u062f\u0627\u062f \u0625\u062d\u0635\u0627\u0626\u064a.<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-family: 'times new roman', times, serif;\"><strong>\u0627\u0644\u0645\u0646\u0627\u0642\u0634\u0629 <\/strong><strong>Discussion<\/strong><\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-family: 'times new roman', times, serif;\">\u062c\u0627\u0621\u062a \u0646\u062a\u0627\u0626\u062c \u0647\u0630\u0647 \u0627\u0644\u062f\u0631\u0627\u0633\u0629 \u0645\u062a\u0648\u0627\u0641\u0642\u0629 \u0645\u0639 \u0645\u0627 \u062a\u0639\u0631\u0636\u0647 \u0627\u0644\u0646\u0634\u0631\u064a\u0627\u062a \u0627\u0644\u0637\u0628\u064a\u0629 \u0645\u0646 \u0646\u0627\u062d\u064a\u0629 \u0632\u064a\u0627\u062f\u0629 \u0639\u0648\u0627\u0645\u0644 \u0627\u0644\u0627\u062e\u062a\u0637\u0627\u0631 \u0627\u0644\u0642\u0644\u0628\u064a\u0629 \u0627\u0644\u0648\u0639\u0627\u0626\u064a\u0629 [\u0632\u064a\u0627\u062f\u0629 BMI \u0648\u0636\u063a\u0637 \u0627\u0644\u062f\u0645 \u0648\u0645\u0642\u0627\u0648\u0645\u0629 \u0627\u0644\u0623\u0646\u0633\u0648\u0644\u064a\u0646 (HOMA-IR) \u0648CRP \u0648TC \u0648TAG \u0648LDL-C \u0648non-HDL-C \u0648\u0627\u0646\u062e\u0641\u0627\u0636 HDL-C] \u0639\u0646\u062f \u0645\u0631\u0636\u0649 \u0627\u0644\u0646\u0645\u0637 \u0627\u0644\u062b\u0627\u0646\u064a \u0645\u0646 \u0627\u0644\u062f\u0627\u0621 \u0627\u0644\u0633\u0643\u0631\u064a \u0645\u0642\u0627\u0631\u0646\u0629 \u0628\u0627\u0644\u0623\u0633\u0648\u064a\u0627\u0621\u061b \u0648\u0643\u0630\u0644\u0643 \u0643\u0627\u0646\u062a \u0634\u062f\u0629 \u0639\u0648\u0627\u0645\u0644 \u0627\u0644\u0627\u062e\u062a\u0637\u0627\u0631 \u0647\u0630\u0647 \u0623\u0639\u0644\u0649 \u0639\u0646\u062f \u0625\u0635\u0627\u0628\u0629 \u0647\u0624\u0644\u0627\u0621 \u0627\u0644\u0645\u0631\u0636\u0649 \u0628\u0645\u0631\u0636 \u0627\u0644\u0642\u0644\u0628 \u0627\u0644\u0625\u0642\u0641\u0627\u0631\u064a.<strong><sup>[4, 7, 11, 16, 18, 21, 32, 43]<\/sup><\/strong> \u0648\u0639\u0644\u0649 \u0627\u0644\u0631\u063a\u0645 \u0645\u0646 \u0627\u0644\u0645\u0639\u0627\u0631\u0641 \u0648\u0627\u0644\u062f\u0631\u0627\u0633\u0627\u062a \u062d\u0648\u0644 \u0627\u0644\u0639\u0644\u0627\u0642\u0629 \u0627\u0644\u0645\u062a\u0628\u0627\u062f\u0644\u0629 \u0644\u0644\u0628\u062f\u0627\u0646\u0629 \u0648\u0645\u0642\u0627\u0648\u0645\u0629 \u0627\u0644\u0623\u0646\u0633\u0648\u0644\u064a\u0646 \u0648\u0627\u0644\u0627\u0644\u062a\u0647\u0627\u0628 \u0648\u0627\u0644\u0646\u0645\u0637 \u0627\u0644\u062b\u0627\u0646\u064a \u0645\u0646 \u0627\u0644\u062f\u0627\u0621 \u0627\u0644\u0633\u0643\u0631\u064a\u060c \u0648\u0627\u0631\u062a\u0628\u0627\u0637 \u0647\u0630\u0647 \u0627\u0644\u0625\u0645\u0631\u0627\u0636\u064a\u0627\u062a \u0628\u0627\u062e\u062a\u0637\u0627\u0631 \u0627\u0644\u0623\u0645\u0631\u0627\u0636 \u0627\u0644\u0642\u0644\u0628\u064a\u0629 \u0627\u0644\u0648\u0639\u0627\u0626\u064a\u0629 \u0627\u0644\u0625\u0642\u0641\u0627\u0631\u064a\u0629\u060c \u0644\u0627 \u062a\u0632\u0627\u0644 \u0627\u0644\u0622\u0644\u064a\u0629 \u0627\u0644\u062d\u0642\u064a\u0642\u064a\u0629 \u0628\u0639\u064a\u062f\u0629 \u0639\u0646 \u0627\u0644\u0641\u0647\u0645 \u0627\u0644\u062a\u0627\u0645 \u0645\u0645\u0627 \u064a\u0633\u062a\u062f\u0639\u064a \u0627\u0644\u0645\u0632\u064a\u062f \u0645\u0646 \u0627\u0644\u0628\u062d\u062b \u0641\u064a\u0647\u0627.<strong><sup>[7, 21, 32]<\/sup><\/strong><\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-family: 'times new roman', times, serif;\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-522 \" src=\"https:\/\/pharmjournal.asscph.com\/wp-content\/uploads\/2022\/04\/1-24-e1698856959705-178x300.png\" alt=\"\" width=\"575\" height=\"969\" \/><\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-family: 'times new roman', times, serif;\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-523 \" src=\"https:\/\/pharmjournal.asscph.com\/wp-content\/uploads\/2022\/04\/1-25-e1698857074837-300x99.png\" alt=\"\" width=\"585\" height=\"193\" srcset=\"https:\/\/pharmjournal.asscph.com\/wp-content\/uploads\/2022\/04\/1-25-e1698857074837-300x99.png 300w, https:\/\/pharmjournal.asscph.com\/wp-content\/uploads\/2022\/04\/1-25-e1698857074837-1024x340.png 1024w, https:\/\/pharmjournal.asscph.com\/wp-content\/uploads\/2022\/04\/1-25-e1698857074837-768x255.png 768w, https:\/\/pharmjournal.asscph.com\/wp-content\/uploads\/2022\/04\/1-25-e1698857074837-1536x509.png 1536w, https:\/\/pharmjournal.asscph.com\/wp-content\/uploads\/2022\/04\/1-25-e1698857074837-2048x679.png 2048w\" sizes=\"auto, (max-width: 585px) 100vw, 585px\" \/><\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-family: 'times new roman', times, serif;\">\u062a\u0644\u0642\u064a \u0646\u062a\u0627\u0626\u062c \u0647\u0630\u0647 \u0627\u0644\u062f\u0631\u0627\u0633\u0629 \u0627\u0644\u0636\u0648\u0621 \u0639\u0644\u0649 \u062f\u0648\u0631 \u0627\u062b\u0646\u064a\u0646 \u0645\u0646 \u0627\u0644\u0623\u062f\u064a\u0628\u0648\u0643\u064a\u0646\u0627\u062a \u0641\u064a \u0625\u0646\u0642\u0627\u0635 \u0627\u0644\u0627\u062e\u062a\u0637\u0627\u0631 \u0627\u0644\u0642\u0644\u0628\u064a \u0627\u0644\u0648\u0639\u0627\u0626\u064a (\u0627\u0644\u0623\u062f\u064a\u0628\u0648\u0646\u0643\u062a\u064a\u0646) \u0648\u0632\u064a\u0627\u062f\u062a\u0647 (\u0627\u0644\u0631\u064a\u0632\u064a\u0633\u062a\u064a\u0646 \u0648\u0646\u0633\u0628\u062a\u0647 \u0625\u0644\u0649 \u0627\u0644\u0623\u062f\u064a\u0628\u0648\u0646\u0643\u062a\u064a\u0646) \u0639\u0646\u062f \u0639\u064a\u0646\u0629 \u0645\u0646 \u0627\u0644\u0645\u0631\u0636\u0649 \u0627\u0644\u0633\u0648\u0631\u064a\u064a\u0646 \u0627\u0644\u0645\u0635\u0627\u0628\u064a\u0646 \u0628\u0627\u0644\u0646\u0645\u0637 \u0627\u0644\u062b\u0627\u0646\u064a \u0645\u0646 \u0627\u0644\u062f\u0627\u0621 \u0627\u0644\u0633\u0643\u0631\u064a. \u0644\u0642\u062f \u0638\u0647\u0631 \u0628\u0648\u0636\u0648\u062d \u0641\u064a \u0647\u0630\u0647 \u0627\u0644\u062f\u0631\u0627\u0633\u0629 \u0623\u0646 \u0645\u0633\u062a\u0648\u064a\u0627\u062a <strong>\u0627\u0644\u0623\u062f\u064a\u0628\u0648\u0646\u0643\u062a\u064a\u0646<\/strong> \u0645\u0646\u062e\u0641\u0636\u0629 \u0639\u0646\u062f \u0627\u0644\u0633\u0643\u0631\u064a\u064a\u0646 \u0645\u0642\u0627\u0631\u0646\u0629 \u0628\u0627\u0644\u0623\u0633\u0648\u064a\u0627\u0621 (<em>0.001&gt;P<\/em>)\u060c \u0643\u0645\u0627 \u0627\u0646\u062e\u0641\u0636\u062a \u0645\u0633\u062a\u0648\u064a\u0627\u062a\u0647 \u0623\u0643\u062b\u0631 \u0639\u0646\u062f\u0645\u0627 \u0627\u0642\u062a\u0631\u0646 \u0627\u0644\u062f\u0627\u0621 \u0627\u0644\u0633\u0643\u0631\u064a \u0628\u0645\u0631\u0636 \u0627\u0644\u0642\u0644\u0628 \u0627\u0644\u0625\u0642\u0641\u0627\u0631\u064a (<em>0.001&gt;P<\/em>) (\u0627\u0644\u062c\u062f\u0648\u0644 2). \u0643\u0645\u0627 \u0643\u0627\u0646\u062a \u0645\u0633\u062a\u0648\u064a\u0627\u062a\u0647 \u0645\u0631\u062a\u0628\u0637\u0629 \u0639\u0643\u0633\u064a\u0627\u064b \u0645\u0639 \u0639\u0648\u0627\u0645\u0644 \u0627\u0644\u0627\u062e\u062a\u0637\u0627\u0631 \u0627\u0644\u0642\u0644\u0628\u064a\u0629 \u0627\u0644\u0648\u0639\u0627\u0626\u064a\u0629 \u062c\u0645\u064a\u0639\u0647\u0627 [\u0632\u064a\u0627\u062f\u0629 BMI \u0648\u0636\u063a\u0637 \u0627\u0644\u062f\u0645 \u0648\u0645\u0642\u0627\u0648\u0645\u0629 \u0627\u0644\u0623\u0646\u0633\u0648\u0644\u064a\u0646 (HOMA-IR) \u0648CRP \u0648TC \u0648TAG \u0648LDL-C \u0648non-HDL-C \u0648\u0627\u0646\u062e\u0641\u0627\u0636 HDL-C] \u0639\u0646\u062f \u0645\u0631\u0636\u0649 \u0627\u0644\u0646\u0645\u0637 \u0627\u0644\u062b\u0627\u0646\u064a \u0645\u0646 \u0627\u0644\u062f\u0627\u0621 \u0627\u0644\u0633\u0643\u0631\u064a \u0627\u0644\u0645\u0635\u0627\u0628\u064a\u0646 \u0628\u0645\u0631\u0636 \u0627\u0644\u0642\u0644\u0628 \u0627\u0644\u0625\u0642\u0641\u0627\u0631\u064a (\u0627\u0644\u062c\u062f\u0648\u0644 3). \u0641\u0636\u0644\u0627\u064b \u0639\u0646 \u0630\u0644\u0643 \u0641\u0642\u062f \u0623\u0648\u062d\u0649 \u062a\u062d\u0644\u064a\u0644 \u0627\u0644\u062a\u062d\u0648\u0641 \u0628\u0627\u0644\u0642\u064a\u0645\u0629 \u0627\u0644\u062a\u0646\u0628\u0624\u064a\u0629 \u0627\u0644\u0648\u0642\u0627\u0626\u064a\u0629 \u0644\u0645\u0633\u062a\u0648\u064a\u0627\u062a \u0627\u0644\u0623\u062f\u064a\u0628\u0648\u0646\u0643\u062a\u064a\u0646 (0.74 = OR\u061b <em>0.001&gt;P<\/em>) \u0639\u0644\u0649 \u0627\u0644\u0645\u0631\u0636 \u0627\u0644\u0642\u0644\u0628\u064a \u0627\u0644\u0625\u0642\u0641\u0627\u0631\u064a (\u0627\u0644\u062c\u062f\u0648\u0644 4)\u061b \u0648\u0647\u0648 \u0645\u0627 \u0623\u062b\u0628\u062a\u062a\u0647 \u0627\u0644\u0645\u0633\u0627\u062d\u0629 \u062a\u062d\u062a \u0645\u0646\u062d\u0646\u0649 AUC \u062e\u0627\u0635\u064a\u0629 \u062a\u0634\u063a\u064a\u0644 \u0627\u0644\u0645\u0633\u062a\u0642\u0628\u0644 ROC \u0648\u0627\u0644\u062a\u064a \u0648\u0635\u0644\u062a \u0625\u0644\u0649 0.812 \u0628\u0627\u0639\u062a\u062f\u0627\u062f \u0623\u0642\u0644 \u0645\u0646 0.001 (\u0627\u0644\u0634\u0643\u0644 1). \u062a\u0648\u062d\u064a \u0647\u0630\u0647 \u0627\u0644\u0645\u0639\u0637\u064a\u0627\u062a \u0643\u0644\u0647\u0627 \u0628\u0627\u0644\u062f\u0648\u0631 \u0627\u0644\u0630\u064a \u064a\u0624\u062f\u0651\u064a\u0647 \u0646\u0642\u0635 \u0627\u0644\u0623\u062f\u064a\u0628\u0648\u0646\u0643\u062a\u064a\u0646 \u0641\u064a \u0625\u0645\u0631\u0627\u0636\u064a\u0629 \u0627\u0644\u0646\u0645\u0637 \u0627\u0644\u062b\u0627\u0646\u064a \u0645\u0646 \u0627\u0644\u062f\u0627\u0621 \u0627\u0644\u0633\u0643\u0631\u064a \u0648\u0639\u0644\u0627\u0642\u0629 \u0645\u0633\u062a\u0648\u064a\u0627\u062a\u0647 \u0645\u0639 \u0639\u0648\u0627\u0645\u0644 \u0627\u0644\u0627\u062e\u062a\u0637\u0627\u0631 \u0627\u0644\u0642\u0644\u0628\u064a\u0629 \u0627\u0644\u0648\u0639\u0627\u0626\u064a\u0629 \u0627\u0644\u0631\u0626\u064a\u0633\u0629 \u0627\u0644\u062a\u064a \u062a\u0632\u064a\u062f \u0639\u0646\u062f \u0645\u0631\u0636\u0649 \u0627\u0644\u0633\u0643\u0631\u064a (\u0645\u0642\u0627\u0648\u0645\u0629 \u0627\u0644\u0623\u0646\u0633\u0648\u0644\u064a\u0646 \u0648\u0627\u0636\u0637\u0631\u0627\u0628 \u0627\u0644\u0634\u062d\u0645\u064a\u0627\u062a \u0648\u0627\u0644\u062d\u0627\u0644\u0629 \u0627\u0644\u0627\u0644\u062a\u0647\u0627\u0628\u064a\u0629) \u0648\u0642\u062f\u0631\u062a\u0647 \u0627\u0644\u062a\u0646\u0628\u0624\u064a\u0629 \u0628\u0627\u0644\u0645\u0631\u0636 \u0627\u0644\u0642\u0644\u0628\u064a \u0627\u0644\u0625\u0642\u0641\u0627\u0631\u064a \u0639\u0646\u062f \u0639\u064a\u0646\u0629 \u0627\u0644\u0645\u0631\u0636\u0649 \u0627\u0644\u0633\u0648\u0631\u064a\u064a\u0646 \u0627\u0644\u0645\u062f\u0631\u0648\u0633\u0629. \u062a\u062a\u0648\u0627\u0641\u0642 \u0647\u0630\u0647 \u0627\u0644\u0646\u062a\u0627\u0626\u062c \u0645\u0639 \u0627\u0644\u062f\u0631\u0627\u0633\u0627\u062a \u0648\u0627\u0644\u0645\u0631\u0627\u062c\u0639\u0627\u062a \u0627\u0644\u062a\u064a \u062a\u062b\u0628\u062a \u0627\u0631\u062a\u0628\u0627\u0637 \u0646\u0642\u0635 \u0627\u0644\u0623\u062f\u064a\u0628\u0648\u0646\u0643\u062a\u064a\u0646 \u0628\u0627\u0644\u0628\u062f\u0627\u0646\u0629 \u0648\u0645\u0642\u0627\u0648\u0645\u0629 \u0627\u0644\u0623\u0646\u0633\u0648\u0644\u064a\u0646 \u0648\u0627\u0644\u0645\u062a\u0644\u0627\u0632\u0645\u0629 \u0627\u0644\u0627\u0633\u062a\u0642\u0644\u0627\u0628\u064a\u0629 \u0648\u0627\u0644\u062d\u0627\u0644\u0629 \u0627\u0644\u0627\u0644\u062a\u0647\u0627\u0628\u064a\u0629 \u0648\u0625\u0645\u0631\u0627\u0636\u064a\u0629 \u0627\u0644\u062f\u0627\u0621 \u0627\u0644\u0633\u0643\u0631\u064a \u0648\u0627\u0636\u0637\u0631\u0627\u0628 \u0634\u062d\u0645\u064a\u0627\u062a \u0627\u0644\u062f\u0645 \u0648\u0627\u0644\u062a\u0635\u0644\u0628 \u0627\u0644\u0639\u0635\u064a\u062f\u064a.<strong><sup>[5, 6, 9, 18, 29, 31, 34, 37, 41, 46, 49, 67-69]<\/sup><\/strong> \u0648\u064a\u0645\u0643\u0646 \u062a\u0641\u0633\u064a\u0631 \u0647\u0630\u0627 \u0627\u0644\u062f\u0648\u0631 \u0627\u0644\u0630\u064a \u064a\u0624\u062f\u0651\u064a\u0647 \u0646\u0642\u0635 \u0627\u0644\u0623\u062f\u064a\u0628\u0648\u0646\u0643\u062a\u064a\u0646 \u0641\u064a \u0625\u0645\u0631\u0627\u0636\u064a\u0629 \u0627\u0644\u062f\u0627\u0621 \u0627\u0644\u0633\u0643\u0631\u064a \u0648\u0627\u0644\u0645\u0631\u0636 \u0627\u0644\u0642\u0644\u0628\u064a \u0627\u0644\u0625\u0642\u0641\u0627\u0631\u064a \u0645\u0646 \u062e\u0644\u0627\u0644 \u0646\u0642\u0635 \u062f\u0648\u0631\u0647 \u0627\u0644\u0633\u0648\u064a \u0627\u0644\u0645\u062a\u0645\u062b\u0644 \u0641\u064a \u0632\u064a\u0627\u062f\u0629 \u0642\u0628\u0637 \u0627\u0644\u063a\u0644\u0648\u0643\u0648\u0632 \u0648\u0627\u0633\u062a\u0647\u0644\u0627\u0643\u0647\u060c \u0648\u062e\u0641\u0636 \u0627\u0633\u062a\u062d\u062f\u0627\u062b \u0627\u0644\u063a\u0644\u0648\u0643\u0648\u0632\u060c \u0648\u0632\u064a\u0627\u062f\u0629 \u062a\u0642\u0648\u064a\u0636 \u0627\u0644\u062f\u0647\u0648\u0646 (\u062a\u0646\u0634\u064a\u0637 \u0627\u0644\u0623\u0643\u0633\u062f\u0629 \u0627\u0644\u0628\u064a\u062a\u0627\u0626\u064a\u0629 \u0644\u0644\u062d\u0645\u0648\u0636 \u0627\u0644\u062f\u0647\u0646\u064a\u0629) \u0648\u0627\u0644\u0648\u0642\u0627\u064a\u0629 \u0645\u0646 \u0627\u0644\u0627\u0633\u062a\u0645\u0627\u062a\u0629 apoptosis \u0648\u062d\u0645\u0627\u064a\u0629 \u0627\u0644\u0639\u0636\u0644\u0629 \u0627\u0644\u0642\u0644\u0628\u064a\u0629 \u0648\u0632\u064a\u0627\u062f\u0629 \u0627\u0644\u062d\u0633\u0627\u0633\u064a\u0629 \u0644\u0644\u0623\u0646\u0633\u0648\u0644\u064a\u0646 \u0648\u062e\u0641\u0636 \u0627\u0644\u062d\u0627\u0644\u0629 \u0627\u0644\u0627\u0644\u062a\u0647\u0627\u0628\u064a\u0629.<strong><sup>[31, 35, 36, 39, 41, 46, 50, 67, 68] <\/sup><\/strong><\/span><span style=\"font-family: 'times new roman', times, serif;\">\u0643\u0645\u0627 \u062a\u062b\u0628\u062a \u0646\u062a\u0627\u0626\u062c \u0627\u0644\u062f\u0631\u0627\u0633\u0629 \u0627\u0644\u062d\u0627\u0644\u064a\u0629 \u062f\u0648\u0631 \u0627\u0644\u0631\u064a\u0632\u064a\u0633\u062a\u064a\u0646 \u0641\u064a \u0625\u0645\u0631\u0627\u0636\u064a\u0629 \u0627\u0644\u0646\u0645\u0637 \u0627\u0644\u062b\u0627\u0646\u064a \u0645\u0646 \u0627\u0644\u062f\u0627\u0621 \u0627\u0644\u0633\u0643\u0631\u064a \u0648\u0639\u0644\u0627\u0642\u0629 \u0645\u0633\u062a\u0648\u064a\u0627\u062a\u0647 \u0645\u0639 \u0639\u0648\u0627\u0645\u0644 \u0627\u0644\u0627\u062e\u062a\u0637\u0627\u0631 \u0627\u0644\u0642\u0644\u0628\u064a\u0629 \u0627\u0644\u0648\u0639\u0627\u0626\u064a\u0629 \u0627\u0644\u0631\u0626\u064a\u0633\u0629 \u0627\u0644\u062a\u064a \u062a\u0632\u064a\u062f \u0639\u0646\u062f \u0645\u0631\u0636\u0649 \u0627\u0644\u0633\u0643\u0631\u064a (\u0645\u0642\u0627\u0648\u0645\u0629 \u0627\u0644\u0623\u0646\u0633\u0648\u0644\u064a\u0646 \u0648\u0627\u0636\u0637\u0631\u0627\u0628 \u0627\u0644\u0634\u062d\u0645\u064a\u0627\u062a \u0648\u0627\u0644\u062d\u0627\u0644\u0629 \u0627\u0644\u0627\u0644\u062a\u0647\u0627\u0628\u064a\u0629) \u0648\u0642\u062f\u0631\u062a\u0647 \u0627\u0644\u062a\u0646\u0628\u0624\u064a\u0629 \u0628\u0627\u0644\u0645\u0631\u0636 \u0627\u0644\u0642\u0644\u0628\u064a \u0627\u0644\u0625\u0642\u0641\u0627\u0631\u064a \u0639\u0646\u062f \u0639\u064a\u0646\u0629 \u0627\u0644\u0645\u0631\u0636\u0649 \u0627\u0644\u0633\u0648\u0631\u064a\u064a\u0646 \u0627\u0644\u0645\u062f\u0631\u0648\u0633\u0629. \u0644\u0642\u062f \u0643\u0627\u0646 \u0648\u0627\u0636\u062d\u0627\u064b \u0627\u0631\u062a\u0641\u0627\u0639 \u0642\u064a\u0645 \u0627\u0644\u0631\u064a\u0632\u064a\u0633\u062a\u064a\u0646 \u0639\u0646\u062f \u0645\u0631\u0636\u0649 \u0627\u0644\u0633\u0643\u0631\u064a \u0648\u062a\u0641\u0627\u0642\u0645 \u0647\u0630\u0627 \u0627\u0644\u0627\u0631\u062a\u0641\u0627\u0639 \u0639\u0646\u062f \u0625\u0635\u0627\u0628\u0629 \u0647\u0624\u0644\u0627\u0621 \u0627\u0644\u0645\u0631\u0636\u0649 \u0628\u0627\u0644\u0645\u0631\u0636 \u0627\u0644\u0625\u0642\u0641\u0627\u0631\u064a \u0627\u0644\u0642\u0644\u0628\u064a (\u0627\u0644\u062c\u062f\u0648\u0644 2)\u060c \u0648\u0627\u0631\u062a\u0628\u0637\u062a \u0645\u0633\u062a\u0648\u064a\u0627\u062a\u0647 \u0625\u064a\u062c\u0627\u0628\u064a\u0627\u064b \u0645\u0639 \u0634\u062f\u0629 \u0639\u0648\u0627\u0645\u0644 \u0627\u062e\u062a\u0637\u0627\u0631 \u0627\u0644\u0645\u0631\u0636 \u0627\u0644\u0642\u0644\u0628\u064a \u0627\u0644\u0625\u0642\u0641\u0627\u0631\u064a \u0627\u0644\u0645\u062e\u062a\u0644\u0641\u0629 [\u0632\u064a\u0627\u062f\u0629 BMI \u0648\u0636\u063a\u0637 \u0627\u0644\u062f\u0645 \u0648\u0645\u0642\u0627\u0648\u0645\u0629 \u0627\u0644\u0623\u0646\u0633\u0648\u0644\u064a\u0646 (HOMA-IR) \u0648CRP \u0648TC \u0648TAG \u0648LDL-C \u0648non-HDL-C \u0648\u0627\u0646\u062e\u0641\u0627\u0636 HDL-C] \u0639\u0646\u062f \u0645\u0631\u0636\u0649 \u0627\u0644\u0646\u0645\u0637 \u0627\u0644\u062b\u0627\u0646\u064a \u0645\u0646 \u0627\u0644\u062f\u0627\u0621 \u0627\u0644\u0633\u0643\u0631\u064a \u0627\u0644\u0645\u0635\u0627\u0628\u064a\u0646 \u0628\u0645\u0631\u0636 \u0627\u0644\u0642\u0644\u0628 \u0627\u0644\u0625\u0642\u0641\u0627\u0631\u064a (\u0627\u0644\u062c\u062f\u0648\u0644 3). \u062b\u0645 \u062c\u0627\u0621\u062a \u0646\u062a\u0627\u0626\u062c \u0627\u062e\u062a\u0628\u0627\u0631 \u0627\u0644\u062a\u062d\u0648\u0641 (1.35 = OR\u061b <em>0.001&gt;P<\/em>) (\u0627\u0644\u062c\u062f\u0648\u0644 4) \u0648\u0627\u0644\u0645\u0633\u0627\u062d\u0629 \u062a\u062d\u062a \u0645\u0646\u062d\u0646\u0649 \u062e\u0627\u0635\u064a\u0629 \u062a\u0634\u063a\u064a\u0644 \u0627\u0644\u0645\u0633\u062a\u0642\u0628\u0644 [0.812=AUC\u061b <em>P<\/em> \u0623\u0642\u0644 \u0645\u0646 0.001 (\u0627\u0644\u0634\u0643\u0644 1)] \u0644\u062a\u062b\u0628\u062a \u0642\u062f\u0631\u0629 \u0645\u0633\u062a\u0648\u064a\u0627\u062a \u0627\u0644\u0631\u064a\u0632\u064a\u0633\u062a\u064a\u0646 \u0639\u0644\u0649 \u0627\u0644\u062a\u0646\u0628\u0624 \u0628\u0627\u0644\u0645\u0631\u0636 \u0627\u0644\u0642\u0644\u0628\u064a \u0627\u0644\u0625\u0642\u0641\u0627\u0631\u064a. \u0648\u0642\u062f \u062c\u0627\u0621\u062a \u0647\u0630\u0647 \u0627\u0644\u0646\u062a\u0627\u0626\u062c \u0645\u062a\u0648\u0627\u0641\u0642\u0629 \u0645\u0639 \u0628\u0639\u0636 \u0627\u0644\u062f\u0631\u0627\u0633\u0627\u062a \u0648\u0627\u0644\u0645\u0631\u0627\u062c\u0639\u0627\u062a \u0627\u0644\u0639\u0644\u0645\u064a\u0629 \u0648\u0645\u062a\u0639\u0627\u0631\u0636\u0629 \u0645\u0639 \u063a\u064a\u0631\u0647\u0627\u060c \u0627\u0644\u0623\u0645\u0631 \u0627\u0644\u0630\u064a \u064a\u0639\u0643\u0633 \u0627\u0644\u062a\u0639\u0627\u0631\u0636 \u0627\u0644\u0645\u0648\u062c\u0648\u062f \u062d\u062a\u0649 \u0627\u0644\u0622\u0646 \u062d\u0648\u0644 \u062f\u0648\u0631 \u0627\u0644\u0631\u064a\u0632\u064a\u0633\u062a\u064a\u0646 \u0641\u064a \u0627\u0644\u0622\u0644\u064a\u0627\u062a \u0627\u0644\u0625\u0645\u0631\u0627\u0636\u064a\u0629\u060c \u0648\u062e\u0635\u0648\u0635\u0627\u064b \u0625\u062b\u0628\u0627\u062a \u0627\u0644\u0639\u0644\u0627\u0642\u0629 \u0628\u064a\u0646 \u0645\u0633\u062a\u0648\u064a\u0627\u062a\u0647 \u0627\u0644\u0645\u0631\u062a\u0641\u0639\u0629 \u0641\u064a \u0627\u0644\u0645\u0635\u0644 \u0639\u0646\u062f \u0627\u0644\u0628\u0634\u0631 \u0648\u0643\u0644 \u0645\u0646 \u0627\u0644\u0628\u062f\u0627\u0646\u0629 \u0648\u0645\u0642\u0627\u0648\u0645\u0629 \u0627\u0644\u0623\u0646\u0633\u0648\u0644\u064a\u0646 \u0648\u0627\u0644\u0646\u0645\u0637 \u0627\u0644\u062b\u0627\u0646\u064a \u0645\u0646 \u0627\u0644\u062f\u0627\u0621 \u0627\u0644\u0633\u0643\u0631\u064a \u0648\u0639\u0648\u0627\u0645\u0644 \u0627\u0644\u0627\u062e\u062a\u0637\u0627\u0631 \u0627\u0644\u0642\u0644\u0628\u064a\u0629 \u0627\u0644\u0648\u0639\u0627\u0626\u064a\u0629 \u0627\u0644\u0634\u062d\u0645\u064a\u0629\u060c \u0639\u0644\u0649 \u0627\u0644\u0631\u063a\u0645 \u0645\u0646 \u0625\u062b\u0628\u0627\u062a \u0623\u0646\u0647 \u064a\u0624\u062b\u0631 \u0641\u064a \u0627\u0633\u062a\u062a\u0628\u0627\u0628 \u0627\u0644\u0623\u0646\u0633\u0648\u0644\u064a\u0646.<strong><sup>[31, 51, 56, 61, 62, 70-73]<\/sup><\/strong> \u0648\u0631\u0628\u0645\u0627 \u064a\u0639\u0648\u062f \u0647\u0630\u0627 \u0627\u0644\u062a\u0639\u0627\u0631\u0636 \u0628\u064a\u0646 \u0627\u0644\u062f\u0631\u0627\u0633\u0627\u062a \u0625\u0644\u0649 \u0635\u063a\u0631 \u062d\u062c\u0645 \u0639\u064a\u0646\u0627\u062a \u0627\u0644\u062f\u0631\u0627\u0633\u0627\u062a \u0648\u0627\u062e\u062a\u0644\u0627\u0641 \u062e\u0635\u0627\u0626\u0635 \u0627\u0644\u062c\u0645\u0647\u0631\u0627\u062a \u0627\u0644\u0645\u062f\u0631\u0648\u0633\u0629\u060c \u0628\u0645\u0627 \u0641\u064a \u0630\u0644\u0643 \u0627\u0644\u0623\u0639\u0631\u0627\u0642\u060c \u0648\u0627\u0633\u062a\u062e\u062f\u0627\u0645 \u0645\u0642\u0627\u064a\u0633\u0627\u062a \u063a\u064a\u0631 \u0645\u0639\u064a\u0651\u0631\u0629 \u0644\u0642\u064a\u0627\u0633 \u0645\u0633\u062a\u0648\u064a\u0627\u062a \u0627\u0644\u0631\u064a\u0632\u064a\u0633\u062a\u064a\u0646.<strong><sup>[70, 74]<\/sup><\/strong> \u0648\u0644\u0639\u0644 \u0627\u0644\u0625\u062c\u0645\u0627\u0639 \u0627\u0644\u0623\u0643\u0628\u0631 \u0641\u064a \u0627\u0644\u062f\u0631\u0627\u0633\u0627\u062a \u0643\u0627\u0646 \u0645\u062a\u0648\u0627\u0641\u0642\u0627\u064b \u0645\u0639 \u0627\u0644\u062f\u0631\u0627\u0633\u0629 \u0627\u0644\u062d\u0627\u0644\u064a\u0629\u060c \u0648\u0647\u0648 \u0645\u0627 \u064a\u062a\u0639\u0644\u0642 \u0628\u0627\u0644\u062f\u0648\u0631 \u0627\u0644\u0630\u064a \u064a\u0624\u062f\u0651\u064a\u0647 \u0627\u0644\u0631\u064a\u0632\u064a\u0633\u062a\u064a\u0646 \u0641\u064a \u0627\u0644\u0627\u0633\u062a\u062c\u0627\u0628\u0629 \u0627\u0644\u0627\u0644\u062a\u0647\u0627\u0628\u064a\u0629 \u0648\u062a\u0646\u0634\u064a\u0637\u0647\u0627 \u0645\u0645\u0627 \u0642\u062f \u064a\u0643\u0648\u0646 \u0646\u0642\u0637\u0629 \u0627\u0644\u0627\u0646\u0637\u0644\u0627\u0642 \u0646\u062d\u0648 \u062a\u0641\u0633\u064a\u0631 \u062f\u0648\u0631\u0647 \u0641\u064a \u0627\u0644\u062d\u062f\u062b\u064a\u0627\u062a \u0627\u0644\u0645\u0631\u0636\u064a\u0629 \u0627\u0644\u0623\u062e\u0631\u0649 \u0643\u0645\u0642\u0627\u0648\u0645\u0629 \u0627\u0644\u0623\u0646\u0633\u0648\u0644\u064a\u0646 \u0648\u0645\u0627 \u064a\u062a\u0628\u0639\u0647\u0627 \u0645\u0646 \u062a\u063a\u064a\u0631\u0627\u062a \u0641\u064a \u0628\u0631\u0648\u0641\u064a\u0644 \u0627\u0644\u0634\u062d\u0645\u064a\u0627\u062a \u0648\u0627\u0644\u0646\u0645\u0637 \u0627\u0644\u062b\u0627\u0646\u064a \u0645\u0646 \u0627\u0644\u062f\u0627\u0621 \u0627\u0644\u0633\u0643\u0631\u064a \u0648\u0625\u062d\u062f\u0627\u062b \u0627\u0644\u062a\u0635\u0644\u0628 \u0627\u0644\u0639\u0635\u064a\u062f\u064a \u0639\u0628\u0631 \u062a\u063a\u064a\u0631\u0627\u062a \u0641\u064a \u0648\u0638\u064a\u0641\u0629 \u0627\u0644\u0628\u0637\u0627\u0646\u0629 \u0627\u0644\u0648\u0639\u0627\u0626\u064a\u0629 \u0627\u0644\u062f\u0645\u0648\u064a\u0629 \u0645\u0646 \u062e\u0644\u0627\u0644 \u0632\u064a\u0627\u062f\u0629 \u062d\u0648\u0627\u062f\u062b \u0627\u0644\u0627\u0646\u062a\u0633\u0627\u062e \u0627\u0644\u0645\u0624\u062f\u064a\u0629 \u0625\u0644\u0649 \u0632\u064a\u0627\u062f\u0629 \u0627\u0644\u062a\u0639\u0628\u064a\u0631 \u0639\u0646 \u0628\u0639\u0636 \u0627\u0644\u0633\u064a\u062a\u0648\u0643\u064a\u0646\u0627\u062a \u0645\u0627\u0642\u0628\u0644 \u0627\u0644\u0627\u0644\u062a\u0647\u0627\u0628\u064a\u0629 \u0645\u062b\u0644 \u0627\u0644\u0625\u0646\u062a\u0631\u0644\u0648\u0643\u064a\u0646\u0627\u062a 1 \u06486 \u064812 \u0648\u0639\u0627\u0645\u0644 \u0646\u062e\u0631 \u0627\u0644\u0648\u0631\u0645-\u0623\u0644\u0641\u0627 \u0648\u063a\u064a\u0631\u0647\u0627.<strong><sup>[5, 9, 11, 14, 18, 31, 32, 37, 38, 51, 55, 60, 61, 63, 70] <\/sup><\/strong><\/span><span style=\"font-family: 'times new roman', times, serif;\">\u0648\u0623\u062e\u064a\u0631\u0627\u064b\u060c \u0641\u0642\u062f \u0623\u062b\u0628\u062a\u062a \u0646\u062a\u0627\u0626\u062c \u0627\u0644\u062f\u0631\u0627\u0633\u0629 \u0627\u0644\u062d\u0627\u0644\u064a\u0629\u060c \u0648\u0644\u0644\u0645\u0631\u0629 \u0627\u0644\u0623\u0648\u0644\u0649 \u0639\u0644\u0649 \u062d\u062f \u0639\u0644\u0645 \u0627\u0644\u0645\u0624\u0644\u0641\u064a\u0646\u060c \u0623\u0646 \u0623\u0641\u0636\u0644 \u0627\u0644\u0639\u0648\u0627\u0645\u0644 \u0627\u0644\u062a\u0646\u0628\u0624\u064a\u0629 \u0628\u0627\u0644\u0645\u0631\u0636 \u0627\u0644\u0642\u0644\u0628 \u0627\u0644\u0625\u0642\u0641\u0627\u0631\u064a \u0647\u0648 \u0646\u0633\u0628\u0629 \u0627\u0644\u0631\u064a\u0632\u064a\u0633\u062a\u064a\u0646 \u0625\u0644\u0649 \u0627\u0644\u0623\u062f\u064a\u0628\u0648\u0646\u0643\u062a\u064a\u0646 \u0627\u0644\u062a\u064a \u062a\u0632\u0627\u064a\u062f\u062a \u0628\u0634\u0643\u0644 \u0645\u0639\u062a\u062f \u0628\u0647 \u0625\u062d\u0635\u0627\u0626\u064a\u0627 \u0645\u0646 \u0645\u062c\u0645\u0648\u0639\u0629 \u0627\u0644\u0623\u0633\u0648\u064a\u0627\u0621 \u0625\u0644\u0649 \u0627\u0644\u0645\u0635\u0627\u0628\u064a\u0646 \u0628\u0627\u0644\u0646\u0645\u0637 \u0627\u0644\u062b\u0627\u0646\u064a \u0645\u0646 \u0627\u0644\u062f\u0627\u0621 \u0627\u0644\u0633\u0643\u0631\u064a \u0644\u062a\u0635\u0644 \u0625\u0644\u0649 \u0627\u0644\u0642\u064a\u0645 \u0627\u0644\u0623\u0639\u0644\u0649 \u0639\u0646\u062f \u0623\u0648\u0644\u0626\u0643 \u0627\u0644\u0633\u0643\u0631\u064a\u064a\u0646 \u0627\u0644\u0645\u0635\u0627\u0628\u064a\u0646 \u0628\u0645\u0631\u0636 \u0627\u0644\u0642\u0644\u0628 \u0627\u0644\u0625\u0642\u0641\u0627\u0631\u064a (\u0627\u0644\u062c\u062f\u0648\u0644 2). \u0648\u062a\u0646\u0627\u0633\u0628\u062a \u0645\u0633\u062a\u0648\u064a\u0627\u062a\u0647\u0627 \u0639\u0646\u062f \u0645\u0631\u0636\u0649 \u0627\u0644\u0642\u0644\u0628 \u0647\u0624\u0644\u0627\u0621 \u0637\u0631\u062f\u0627\u064b \u0645\u0639 \u0634\u062f\u0629 \u0639\u0648\u0627\u0645\u0644 \u0627\u062e\u062a\u0637\u0627\u0631 \u0627\u0644\u0645\u0631\u0636 \u0627\u0644\u0642\u0644\u0628\u064a \u0627\u0644\u0625\u0642\u0641\u0627\u0631\u064a \u0627\u0644\u0645\u062e\u062a\u0644\u0641\u0629 [\u0632\u064a\u0627\u062f\u0629 BMI \u0648\u0636\u063a\u0637 \u0627\u0644\u062f\u0645 \u0648\u0645\u0642\u0627\u0648\u0645\u0629 \u0627\u0644\u0623\u0646\u0633\u0648\u0644\u064a\u0646 (HOMA-IR) \u0648CRP \u0648TC \u0648TAG \u0648LDL-C \u0648non-HDL-C \u0648\u0627\u0646\u062e\u0641\u0627\u0636 HDL-C] (\u0627\u0644\u062c\u062f\u0648\u0644 3) \u0648\u0623\u0639\u0637\u062a \u0623\u0639\u0644\u0649 \u0642\u064a\u0645\u0629 \u0644\u0646\u0633\u0628\u0629 \u0627\u0644\u0623\u0631\u062c\u062d\u064a\u0629 \u0641\u064a \u0627\u062e\u062a\u0628\u0627\u0631 \u0627\u0644\u062a\u062d\u0648\u0641 (1.67 = OR\u061b <em>0.001&gt;P<\/em>) (\u0627\u0644\u062c\u062f\u0648\u0644 4) \u0648\u0623\u0639\u0644\u0649 \u0642\u064a\u0645\u0629 \u0644\u0644\u0645\u0633\u0627\u062d\u0629 \u062a\u062d\u062a \u0645\u0646\u062d\u0646\u0649 \u062e\u0627\u0635\u064a\u0629 \u062a\u0634\u063a\u064a\u0644 \u0627\u0644\u0645\u0633\u062a\u0642\u0628\u0644 [0.850=AUC\u061b <em>P<\/em> \u0623\u0642\u0644 \u0645\u0646 0.001 (\u0627\u0644\u0634\u0643\u0644 1)]. \u0648\u0631\u0628\u0645\u0627 \u062a\u0639\u0643\u0633 \u0647\u0630\u0647 \u0627\u0644\u0646\u0633\u0628\u0629 \u0627\u0644\u0645\u062d\u0635\u0644\u0629 \u0627\u0644\u0646\u0647\u0627\u0626\u064a\u0629 \u0644\u0644\u0623\u0641\u0639\u0627\u0644 \u0627\u0644\u0645\u062a\u0639\u0627\u0643\u0633\u0629 \u0627\u0644\u062a\u064a \u064a\u0645\u0627\u0631\u0633\u0647\u0627 \u0647\u0630\u0627\u0646 \u0627\u0644\u0647\u0631\u0645\u0648\u0646\u0627\u0646 \u0639\u0644\u0649 \u0627\u0644\u062d\u0627\u0644\u0629 \u0627\u0644\u0627\u0633\u062a\u0642\u0644\u0627\u0628\u064a\u0629 \u0648\u0627\u0644\u0627\u0644\u062a\u0647\u0627\u0628\u064a\u0629 \u0644\u062c\u0633\u0645 \u0627\u0644\u0625\u0646\u0633\u0627\u0646. \u0648\u0644\u0639\u0644 \u0645\u0646 \u0627\u0644\u0645\u0641\u064a\u062f \u0627\u0644\u0628\u062d\u062b \u0623\u0643\u062b\u0631 \u0641\u064a \u0647\u0630\u0647 \u0627\u0644\u0646\u0642\u0637\u0629 \u0645\u0646 \u062e\u0644\u0627\u0644 \u062f\u0631\u0627\u0633\u0627\u062a \u0623\u0643\u062b\u0631 \u062a\u062e\u0635\u0635\u0627\u064b \u0648\u0628\u062d\u062c\u0645 \u0639\u064a\u0646\u0629 \u0623\u0643\u0628\u0631 \u062a\u0634\u0645\u0644 \u0645\u062e\u062a\u0644\u0641 \u062f\u0631\u062c\u0627\u062a \u0627\u0644\u0628\u062f\u0627\u0646\u0629 \u0648\u0645\u0642\u0627\u0648\u0645\u0629 \u0627\u0644\u0623\u0646\u0633\u0648\u0644\u064a\u0646.<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-family: 'times new roman', times, serif;\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-524 \" src=\"https:\/\/pharmjournal.asscph.com\/wp-content\/uploads\/2022\/04\/1-26-e1698857261506-300x242.png\" alt=\"\" width=\"574\" height=\"463\" srcset=\"https:\/\/pharmjournal.asscph.com\/wp-content\/uploads\/2022\/04\/1-26-e1698857261506-300x242.png 300w, https:\/\/pharmjournal.asscph.com\/wp-content\/uploads\/2022\/04\/1-26-e1698857261506-1024x824.png 1024w, https:\/\/pharmjournal.asscph.com\/wp-content\/uploads\/2022\/04\/1-26-e1698857261506-768x618.png 768w, https:\/\/pharmjournal.asscph.com\/wp-content\/uploads\/2022\/04\/1-26-e1698857261506-1536x1237.png 1536w, https:\/\/pharmjournal.asscph.com\/wp-content\/uploads\/2022\/04\/1-26-e1698857261506-2048x1649.png 2048w\" sizes=\"auto, (max-width: 574px) 100vw, 574px\" \/><\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-family: 'times new roman', times, serif;\"><strong>\u0627\u0644\u0627\u0633\u062a\u0646\u062a\u0627\u062c <\/strong><strong>Conclusion<\/strong><\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-family: 'times new roman', times, serif;\">\u0623\u0644\u0642\u062a \u0627\u0644\u062f\u0631\u0627\u0633\u0629 \u0627\u0644\u062d\u0627\u0644\u064a\u0629 \u0627\u0644\u0636\u0648\u0621 \u0639\u0644\u0649 \u0627\u062e\u062a\u0644\u0627\u0641 \u0645\u0633\u062a\u0648\u064a\u0627\u062a \u0627\u0644\u0631\u064a\u0632\u064a\u0633\u062a\u064a\u0646 \u0648\u0627\u0644\u0623\u062f\u064a\u0628\u0648\u0646\u0643\u062a\u064a\u0646 \u0648\u0627\u0644\u0646\u0633\u0628\u0629 \u0628\u064a\u0646\u0647\u0645\u0627 \u0628\u064a\u0646 \u0627\u0644\u0623\u0633\u0648\u064a\u0627\u0621 \u0648\u0645\u0631\u0636\u0649 \u0627\u0644\u0633\u0643\u0631\u064a \u0648\u0645\u0631\u0636\u0649 \u0627\u0644\u0642\u0644\u0628 \u0627\u0644\u0625\u0642\u0641\u0627\u0631\u064a \u0627\u0644\u0633\u0643\u0631\u064a\u064a\u0646. \u0644\u0642\u062f \u0627\u0631\u062a\u0628\u0637\u062a \u0627\u0644\u0645\u0633\u062a\u0648\u064a\u0627\u062a \u0627\u0644\u0645\u0646\u062e\u0641\u0636\u0629 \u0645\u0646 \u0627\u0644\u0623\u062f\u064a\u0628\u0648\u0646\u0643\u062a\u064a\u0646 \u0648\u0627\u0644\u0645\u0633\u062a\u0648\u064a\u0627\u062a \u0627\u0644\u0645\u0631\u062a\u0641\u0639\u0629 \u0645\u0646 \u0627\u0644\u0631\u064a\u0632\u064a\u0633\u062a\u064a\u0646 \u0645\u0639 \u0634\u062f\u0629 \u0639\u0648\u0627\u0645\u0644 \u0627\u0644\u062e\u062a\u0637\u0627\u0631 \u0627\u0644\u0642\u0644\u0628\u064a\u0629 \u0627\u0644\u0648\u0639\u0627\u0626\u064a\u0629 \u0627\u0644\u0645\u062e\u062a\u0644\u0641\u0629 \u0639\u0646\u062f \u0645\u0631\u0636\u0649 \u0627\u0644\u0633\u0643\u0631\u064a \u0627\u0644\u0645\u0635\u0627\u0628\u064a\u0646 \u0628\u0645\u0631\u0636 \u0627\u0644\u0642\u0644\u0628 \u0627\u0644\u0625\u0642\u0641\u0627\u0631\u064a \u0648\u0623\u0648\u062d\u062a \u0628\u0625\u0645\u0643\u0627\u0646 \u0627\u0633\u062a\u062e\u062f\u0627\u0645\u0647\u0645\u0627 \u0648\u0627\u0635\u0645\u064a\u0646 \u062d\u064a\u0648\u064a\u064a\u0646 \u0645\u0641\u064a\u062f\u064a\u0646 \u0648\u0639\u0627\u0645\u0644\u0627\u064b \u062a\u0646\u0628\u0624\u064a\u0627\u064b \u0648\u0647\u062f\u0641\u0627\u064b \u0639\u0644\u0627\u062c\u064a\u0627\u064b \u0641\u064a \u062d\u0627\u0644\u0627\u062a \u0627\u0644\u0628\u062f\u0627\u0646\u0629 \u0648\u0645\u0627 \u064a\u0631\u0627\u0641\u0642\u0647\u0627 \u0645\u0646 \u0645\u0642\u0627\u0648\u0645\u0629 \u0644\u0644\u0623\u0646\u0633\u0648\u0644\u064a\u0646 \u0648\u0627\u0644\u0646\u0645\u0637 \u0627\u0644\u062b\u0627\u0646\u064a \u0645\u0646 \u0627\u0644\u062f\u0627\u0621 \u0627\u0644\u0633\u0643\u0631\u064a \u0648\u0645\u0631\u0636 \u0627\u0644\u0642\u0644\u0628 \u0627\u0644\u0625\u0642\u0641\u0627\u0631\u064a. \u0643\u0645\u0627 \u0623\u0648\u062d\u062a \u0627\u0644\u062f\u0631\u0627\u0633\u0629 \u0628\u0627\u0644\u062f\u0648\u0631 \u0627\u0644\u062a\u0646\u0628\u0624\u064a \u0627\u0644\u0625\u0646\u0630\u0627\u0631\u064a \u0627\u0644\u0645\u0647\u0645 \u0644\u0646\u0633\u0628\u0629 \u0627\u0644\u0631\u064a\u0632\u064a\u0633\u062a\u064a\u0646 \u0625\u0644\u0649 \u0627\u0644\u0623\u062f\u064a\u0628\u0648\u0646\u0643\u062a\u064a\u0646 \u0641\u064a \u062d\u0627\u0644\u0627\u062a \u0627\u0644\u0645\u0631\u0636 \u0627\u0644\u0642\u0644\u0628\u064a \u0627\u0644\u0625\u0642\u0641\u0627\u0631\u064a\u060c \u0627\u0644\u0623\u0645\u0631 \u0627\u0644\u0630\u064a \u064a\u062d\u062a\u0627\u062c \u0625\u0644\u0649 \u0627\u0644\u0645\u0632\u064a\u062f \u0645\u0646 \u0627\u0644\u062f\u0631\u0627\u0633\u0627\u062a \u0627\u0644\u0645\u062a\u062e\u0635\u0635\u0629 \u0644\u0625\u062b\u0628\u0627\u062a \u0647\u0630\u0647 \u0627\u0644\u0642\u064a\u0645\u0629 \u0648\u0627\u0644\u0625\u0641\u0627\u062f\u0629 \u0645\u0646\u0647\u0627 \u0641\u064a \u0645\u062c\u0627\u0644 \u0627\u0644\u062a\u062e\u0641\u064a\u0641 \u0645\u0646 \u0639\u0648\u0627\u0645\u0644 \u0627\u0644\u0627\u062e\u062a\u0637\u0627\u0631 \u0627\u0644\u0642\u0644\u0628\u064a\u0629 \u0627\u0644\u0648\u0639\u0627\u0626\u064a\u0629 \u0627\u0644\u0645\u062e\u062a\u0644\u0641\u0629.<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u0627\u0644\u0645\u0642\u062f\u0645\u0629 Introduction: \u0627\u0644\u0623\u0645\u0631\u0627\u0636 \u0627\u0644\u0642\u0644\u0628\u064a\u0629 \u0627\u0644\u0648\u0639\u0627\u0626\u064a\u0629 \u0647\u064a \u0627\u0644\u0633\u0628\u0628 \u0627\u0644\u0623\u0648\u0644 \u0644\u0644\u0648\u0641\u064a\u0627\u062a \u0639\u0627\u0644\u0645\u064a\u0627\u064b\u060c \u0648\u0647\u064a \u0627\u0644\u0645\u0633\u0624\u0648\u0644\u0629 \u0639\u0646 \u062b\u0644\u062b \u0627\u0644\u0648\u0641\u064a\u0627\u062a \u0627\u0644\u0639\u0627\u0644\u0645\u064a\u0629 \u062a\u0642\u0631\u064a\u0628\u0627\u064b.[1-3] \u0648\u0627\u0644\u0623\u0643\u062b\u0631 \u0627\u0646\u062a\u0634\u0627\u0631\u0627\u064b \u0628\u064a\u0646 \u0647\u0630\u0647 \u0627\u0644\u0623\u0645\u0631\u0627\u0636&#8230; <br \/><a href=\"https:\/\/pharmjournal.asscph.com\/?p=180\">\u0627\u0642\u0631\u0623 \u0627\u0644\u0645\u0632\u064a\u062f<\/a><\/p>\n","protected":false},"author":1,"featured_media":524,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[136],"tags":[],"class_list":["post-180","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-136","issue-133","volume-8"],"acf":[],"_links":{"self":[{"href":"https:\/\/pharmjournal.asscph.com\/index.php?rest_route=\/wp\/v2\/posts\/180","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/pharmjournal.asscph.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/pharmjournal.asscph.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/pharmjournal.asscph.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/pharmjournal.asscph.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=180"}],"version-history":[{"count":0,"href":"https:\/\/pharmjournal.asscph.com\/index.php?rest_route=\/wp\/v2\/posts\/180\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/pharmjournal.asscph.com\/index.php?rest_route=\/wp\/v2\/media\/524"}],"wp:attachment":[{"href":"https:\/\/pharmjournal.asscph.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=180"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/pharmjournal.asscph.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=180"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/pharmjournal.asscph.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=180"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}